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Conjoined twins

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https://www.readbyqxmd.com/read/28621033/dicephalic-parapagus-conjoined-twins-in-a-large-fruit-eating-bat-genus-artibeus-chiroptera-phyllostomidae
#1
M R Nogueira, A Ventura, C C P da Veiga, L R Monteiro, N L Pinheiro, A L Peracchi
Conjoined twinning is an embryological anomaly rarely reported in wild mammals and with only two previous records in Chiroptera. Here, we report a case of dicephalic parapagus conjoined twins in the Neotropical phyllostomid genus Artibeus. These twins are males and present separated heads and necks, but a conjoined trunk with an expanded upper thoracic region. They developed two complete forelimbs and two complete hindlimbs, all laterally to the trunk. There is a volume in the upper midback and between the heads that resembles a third rudimentary medial forelimb, but X-ray images only suggest the presence of medial skeletal elements of the pectoral girdle (clavicle and scapulae) in this region...
June 16, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28611167/fetal-mri-of-thoraco-omphalopagus-conjoined-twins
#2
Hazrini Abdullah, Nyazirah Abdul Wahab, Khatijah Abu Bakar
No abstract text is available yet for this article.
June 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28567407/roshan-s-telemedicine-expanding-the-frontier-of-quality-healthcare-through-mobile-technology
#3
Shainoor Khoja
The article highlights the power of mobile technology in expanding access to quality healthcare by telling the story of the first successful operation by Afghan doctors to separate conjoined twins at The French Medical Institute for Mothers and Children (FMIC) in Kabul, Afghanistan's capital. Roshan, Afghanistan's leading telecommunications provider, set up the telemedicine link in 2007, connecting three hospitals in Kandahar, Bamiyan and Badakhshan Provinces to FMIC in Kabul, and all three to one of the best and most modern hospitals in the region: The Aga Khan University Hospital in Karachi, Pakistan...
2017: MHealth
https://www.readbyqxmd.com/read/28559234/etiology-and-clinical-presentation-of-birth-defects-population-based-study
#4
Marcia L Feldkamp, John C Carey, Janice L B Byrne, Sergey Krikov, Lorenzo D Botto
Objective To assess causation and clinical presentation of major birth defects.Design Population based case cohort.Setting Cases of birth defects in children born 2005-09 to resident women, ascertained through Utah's population based surveillance system. All records underwent clinical re-review.Participants 5504 cases among 270 878 births (prevalence 2.03%), excluding mild isolated conditions (such as muscular ventricular septal defects, distal hypospadias).Main outcome measures The primary outcomes were the proportion of birth defects with a known etiology (chromosomal, genetic, human teratogen, twinning) or unknown etiology, by morphology (isolated, multiple, minors only), and by pathogenesis (sequence, developmental field defect, or known pattern of birth defects)...
May 30, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28298949/first-trimester-diagnosis-of-conjoined-twins-in-a-multifetal-pregnancy-after-assisted-reproduction-technique-using-hdlive-rendering
#5
Pedro Teixeira Castro, Heron Werner, Edward Araujo Júnior
No abstract text is available yet for this article.
March 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/28251228/conjoined-twins-in-a-triplet-pregnancy-a-rare-obstetrical-dilemma
#6
Huseyin C Ozcan, Mete G Ugur, Aynur Mustafa, Irfan Kutlar
Conjoined twins are derived from division of a single fertilized ovum after the twelfth day of fertilization. Triplet conjoined twin is considered as a unique phenomenon that is accompanied with a wide variety of congenital abnormalities and also hazardous consequences for both fetuses and parents. We present an extremely rare case of conjoined twins in a triplet pregnancy with symmetric thoracoomphalopagus that was diagnosed in prenatal period by using ultrasound scanning and MRI. In triplet pregnancies, we should be aware about the possibility of conjoined twins...
March 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28231064/three-dimensional-ultrasound-for-prenatal-assessment-of-conjoined-twins-additional-advantages
#7
Tuangsit Wataganara, Pornpimol Ruangvutilert, Prasert Sunsaneevithayakul, Kusol Russameecharoen, Katika Nawapun, Nisarat Phithakwatchara
Conjoined twins are a rare, but serious, complication of monozygotic twins. Early prenatal diagnosis of conjoined twins is increasingly made with transvaginal ultrasound and color Doppler studies. Most prenatally diagnosed conjoined twins are terminated due to the high perinatal mortality, but advancement in pediatric surgery has allowed for successful postnatal separation in a small number of cases, and some parents may consider this option over termination of pregnancy. It is important to get a detailed prenatal ultrasound for the site and extent of fusion for an accurate categorization...
February 23, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28202184/high-prevalence-of-same-sex-twins-in-patients-with-cloacal-exstrophy-support-for-embryological-association-with-monozygotic-twinning
#8
Brenna S Fullerton, Eric A Sparks, Amber M Hall, Cristine S Velazco, Biren P Modi, Dennis P Lund, Tom Jaksic, W Hardy Hendren
PURPOSE: Previous studies have hypothesized that cloacal exstrophy may be caused by errors early in embryological development related to monozygotic twinning. This study reports the prevalence of twins in a large cohort of patients with cloacal exstrophy. METHODS: Patients with cloacal exstrophy treated 1974-2015 were reviewed for reports of multiple gestation or conjoined twinning. The genetic sex of the patient and their twin, and any mention of anomaly in the twin were recorded...
May 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28195364/conjoined-twins-from-conception-to-separation-a-review
#9
REVIEW
Asma Mian, Nader Ishak Gabra, Tanuj Sharma, Nitsa Topale, Jerzy Gielecki, R Shane Tubbs, Marios Loukas
Conjoined twins are suggested to result from aberrant embryogenesis. The two main theories proposed to explain the phenomena are fission and fusion. The incidence rate is 1 in 50,000 births; however, since about 60% of the cases are stillborn, the true incidence is approximated at 1 in 200,000. There is a higher predisposition towards female than male gender with a ratio of 3:1. Conjoined twins are classified based upon the site of attachment. The extent of organ sharing, especially the heart, determines the possibility and prognosis of a separation procedure...
April 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28190730/leftward-flow-determines-laterality-in-conjoined-twins
#10
Matthias Tisler, Thomas Thumberger, Isabelle Schneider, Axel Schweickert, Martin Blum
Conjoined twins fused at the thorax display an enigmatic left-right defect: although left twins are normal, laterality is disturbed in one-half of right twins [1-3]. Molecularly, this randomization corresponds to a lack of asymmetric Nodal cascade induction in right twins [4]. We studied leftward flow [5, 6] at the left-right organizer (LRO) [7, 8] in thoracopagus twins in Xenopus, which displayed a duplicated, fused, and ciliated LRO. Cilia were motile and produced a leftward flow from the right LRO margin of the right to the left margin of the left twin...
February 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28186636/triplet-pregnancy-from-the-transfer-of-two-blastocysts-demonstrating-a-twin-reversed-arterial-perfusion-sequence-with-a-conjoined-twins-pump-fetus
#11
Hongxia Yuan, Qichang Zhou, Jing Li, Shi Zeng
No abstract text is available yet for this article.
February 10, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28132423/xenopus-an-ideal-model-organism-to-study-laterality-in-conjoined-twins
#12
REVIEW
Matthias Tisler, Axel Schweickert, Martin Blum
Conjoined twins occur at low frequency in all vertebrates including humans. Many twins fused at the chest or abdomen display a very peculiar laterality defect: while the left twin is normal with respect to asymmetric organ morphogenesis and placement (situs solitus), the organ situs is randomized in right twins. Although this phenomenon has fascinated already some of the founders of experimental embryology in the 19th and early 20th century, such as Dareste, Fol, Warynsky and Spemann, its embryological basis has remained enigmatic...
January 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28051055/thoracic-heteropagus-conjoined-twins-associated-to-an-omphalocele-report-of-a-case-and-complete-review-of-the-literature
#13
Kotti Ahmed, Ben Dhaou Mahdi, Zitouni Hayet, Louati Hamdi, Jallouli Mohamed, Mhiri Riadh
Heteropagus twins are an extremely rare event with an incidence of 1-2 million live births that represents, sometimes, a real challenge for paediatric surgeons. The majority of cases have complete or partial duplication of the pelvis and/or lower extremities. Thoracic heteropagus conjoined twins is a rare condition in which a grossly defective foetus (the parasite) is attached to the thorax of the main foetus (the autosite). We describe a case of a parasitic heteropagus attached at the chest wall with a rare presentation of giant exomphalos on the autosite...
October 2016: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/28038484/-the-first-record-of-the-delivery-of-conjoined-twins-in-the-srem-county-in-the-19th-century
#14
Jovan Maksimović, Marko Maksimović
In this paper is presented the first original document of the delivery of conjoined twins on the territory of the present-day Vojvodina. The document number 1224 consists of two handwritten quires. On the first page of the first quire are a description and a drawing of the delivered twins. The delivery was described and drawn by Dr. Ernest Furjaković, a shire physician in Ruma and the secondary physicus of the Srem County, who attended and handled the delivery. The conjoined twins were delivered in the night between 2 and 3 April 1852 in Mali Radinci, a small village in the Srem County nearby Ruma, in the far south of the Habsburg Monarchy...
December 2016: Acta Medico-historica Adriatica: AMHA
https://www.readbyqxmd.com/read/27977489/conjoined-twin-separation-integration-of-three-dimensional-modeling-for-optimization-of-surgical-planning
#15
Benjamin C Wood, Sarah R Sher, Benjamin J Mitchell, Albert K Oh, Gary F Rogers, Michael J Boyajian
Conjoined twinning is a rare anomaly, with an incidence of approximately 1 in 100,000 live births. There is a high perinatal mortality rate, but twins who survive pose reconstructive challenges that require meticulous preoperative planning. The authors describe the senior surgeon's career experience with conjoined twin separation, and the evolution of medical modeling and 3-dimensional imaging as a critical component in presurgical planning.The authors performed a retrospective review of all consecutive patients of conjoined twin separation at a single institution from January 2004 to December 2013...
January 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27942061/anaesthetic-challenges-in-conjoined-twins-separation-surgery
#16
Suvarna Kaniyil, Priyanka Pavithran, K K Mubarak, Taznim Mohamed
Conjoined twins are a rare congenital anomaly of unknown aetiology. We report the successful anaesthetic management of separation of ischiopagus tetrapus conjoined twins. The importance of a multidisciplinary approach, thorough pre-operative evaluation and planning, vigilant monitoring and anticipation of complications such as massive blood and fluid loss, haemodynamic instability, hypothermia and intensive, post-operative care are emphasised.
November 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27895537/tissue-expansion-in-children
#17
REVIEW
Tara L Braun, Kristy L Hamilton, Laura A Monson, Edward P Buchanan, Larry H Hollier
Tissue expansion is a well-established surgical method that has been creatively applied to the management of many congenital and acquired pediatric conditions, including the removal of giant congenital melanocytic nevi and the separation of conjoined twins. Careful preoperative planning and patient follow-up are required to achieve the proper results and minimize complications. Special considerations for pediatric patients are present during each step of the process, from patient selection to postoperative care...
November 2016: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/27872725/a-case-of-monocephalusrachipagus-tribrachius-tetrapus-in-a-puppy
#18
Adonis Pino, Arlenis Pérez, Aine Seavers, Guillermo Hermo
Caudal duplication (dipygus) is an uncommon pathologic of conjoined twinning. The conjoined malformation is classified according to the nature and site of the union. We report the presence of this malformation in a female crossbreed puppy. The puppy was delivered by caesarean section following a prolonged period of dystocia. External findings showed a single head (monocephalus) and a normal cranium with no fissure in the medial line detected. The thorax displayed a caudal duplication arising from the lumbosacral region (rachipagus)...
2016: Veterinary Research Forum
https://www.readbyqxmd.com/read/27832667/simulation-based-patient-specific-multidisciplinary-team-training-in-preparation-for-the-resuscitation-and-stabilization-of-conjoined-twins
#19
Nicole K Yamada, Janene H Fuerch, Louis P Halamek
The resuscitation of conjoined twins is a rare and complex clinical challenge. We detail how patient-specific, in situ simulation can be used to prepare a large, multidisciplinary team of health care professionals (HCPs) to deliver safe, efficient, and effective care to such patients. In this case, in situ simulation allowed an 18-person team to address the clinical and ergonomic challenges anticipated for this neonatal resuscitation. The HCPs trained together as an intact team in the actual delivery room environment to probe for human and system weaknesses prior to this unique delivery, and optimized communication, teamwork, and other behavioral skills as they prepared for the simultaneous resuscitation of two patients who were physically joined to one another...
May 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/27783004/separation-of-thoraco-omphalo-ischiopagus-conjoined-twins-surgical-planning-management-and-outcomes
#20
Jeffrey G Trost, Lawrence O Lin, Sarah Jane Clark, David Y Khechoyan, Larry H Hollier, Edward P Buchanan
BACKGROUND: Conjoined twins are a rare medical phenomenon that offers a unique challenge for medical professionals. The complex anatomy of conjoined twins dictates their survival and amenability to separation, making each case different in terms of medical management, surgical planning, and patient outcomes. Thoraco-omphalo-ischiopagus twins, joined from the thorax to the pelvis, are one of the rarest orientations recorded in the medical literature, and successful separation of this subset of conjoined twins has not been documented...
November 2016: Plastic and Reconstructive Surgery
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