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Conjoined twins

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https://www.readbyqxmd.com/read/29657701/early-prenatal-diagnosis-of-parapagus-conjoined-twins
#1
Ângela Melo, Rita Dinis, António Portugal, Ana Isabel Sousa, Isabel Cerveira
Conjoined twinning occurs in 1/100 of monozygotic twins, 1/50,000 gestations and 1/250,000 live births. It is the consequence of a division event at the primitive streak stage of the human embryonic development, about 13-14 days after fertilisation, in monochorionic monoamniotic gestations. A healthy pregnant woman, Gravida 2 Para 1, was admitted into our Fetal Medicine Unit to perform the first trimester ultrasound. A diagnosis of conjoined parapagus twinning based on ultrasound features was made at 11 weeks of gestation, and the couple decided to terminate the pregnancy...
March 28, 2018: Clinics and Practice
https://www.readbyqxmd.com/read/29622914/tail-like-congenital-duplication-of-lower-extremity-extra-leg-or-vestigial-parasitic-twin
#2
Temesgen Mekonnen
Background: Congenital duplication of lower extremity, either complete or incomplete is extremely rare. Only 26 cases had been reported till 2010, of which only 5 cases had feature of complete duplication. Theories have been proposed that the cause of this abnormality includes maternal factors like diabetes and usage of teratogenic drugs. Duplication of lower extremity may mimic that of vestigial parasitic twin; phenotypically, it appears as an individual with extra appendage or limbs...
January 2018: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29547166/surgical-nuances-in-the-separation-of-craniopagus-twins-our-experience-and-a-follow-up-of-15-years
#3
Muralidhar Pai K, R Chandrasekhar Naidu, A Raja, Y S Rai, Niranjan Kumar, Anand Kini, Santhosh Joseph, Vinod Hegde, H S Ballal, Ramoorthi Rao, Saroja V Sharma, Vinay Kumar Valakatte
Craniopagus twins are conjoined twins fused at the cranium. This is the rarest anomaly seen in conjoined twins and craniopagus twins account for 2- 6% of conjoined twins. Conjoined twins are also extremely rare, with the anomaly seen in about 10-20 subjects per billion births. A female preponderance has been noted. Craniopagus twins can be classified into complete or partial, depending on whether or not they have shared dural venous sinuses. They can be further classified into angular or total depending on the alignment of the inter-twin longitudinal axis...
March 2018: Neurology India
https://www.readbyqxmd.com/read/29542428/a-possible-twin-the-1960s-twin-study-revisited-twin-research-twin-to-twin-heart-transplantation-distinguishing-monozygotic-twins-twin-conceptions-via-oocyte-donation-factors-affecting-craniofacial-traits-in-the-media-triplet-delivery-in-the-uk-conjoined-twins
#4
Nancy L Segal
This article begins with the story of a 51-year-old Los Angeles, California man, Justin Goldberg, whose daughter caught a glimpse of his striking look-alike at a popular market. Many people have so-called doppelgängers, but this occurrence is especially intriguing - the individual in question, born in New York City in the mid-1960s to an unwed mother, was an adoptee placed by the Louise Wise Adoption Agency. This agency, under the guidance of a prominent psychiatrist, decided to place twins in separate homes...
March 15, 2018: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29482703/epigastric-heteropagus-conjoined-twins
#5
Arshad Khushdil, Hafsa Niaz, Zeeshan Ahmed
Heteropagus twins are an extremely rare form of asymmetrical conjoined monochorial, monoamniotic twins with an estimated incidence of less than one per one million live births. An often used synonym is parasitic twins. We report a very rare case of epigastric heteropagus twins with a large omphalocoele. The parasite had fully formed pelvis, lower limbs and upper limbs with male genitalia and it was attached to the autosite in the epigastrium.
March 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29446009/the-ethics-of-separating-conjoined-twins-two-arguments-against
#6
Luke Kallberg
I argue that the separation of conjoined twins in infancy or early childhood is unethical (rare exceptions aside). Cases may be divided into three types: both twins suffer from lethal abnormalities, only one twin has a lethal abnormality, or neither twin does. In the first kind of case, there is no reason to separate, since both twins will die regardless of treatment. In the third kind of case, I argue that separation at an early age is unethical because the twins are likely to achieve an irreplaceably good quality of life-the goods of conjoinment-that separation takes away...
February 2018: Theoretical Medicine and Bioethics
https://www.readbyqxmd.com/read/29445482/successful-management-of-a-parasitic-ischiopagus-conjoined-twins-in-a-low-income-setting
#7
Arlindo Rosario Muhelo, Genni Montemezzo, Liviana Da Dalt, Olivier Manzungu Wingi, Daniele Trevisanuto, Piergiorgio Gamba, Damiano Pizzol, Elena Cavaliere
Ischiopagus parasites are fetal defects attached to a relatively normal twin by pelvis. This is the first reported case of parasitic ischiopagus twins without prenatal diagnosis successfully managed in Mozambique. A multidisciplinary team was involved in the supernumerary limbs excision. After 7 months, the infant has a normal development.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29401126/successful-separation-of-conjoined-twins-the-contemporary-experience-and-historic-review-in-memphis
#8
Terri Lynn Carlson, Robyn Daugherty, Amie Miller, Uzoma Ben Gbulie, Robert Wallace
Conjoined twins are a rare phenomenon with historically poor outcomes after separation. We present a review of 8 sets of conjoined twins operated on in Memphis, Tenn, from 1953-2016. Except for 1 set of twins, before 2010, all experienced at least 1 fatality either before, during, or as a result of separation. Since 2010, we have separated an additional 2 sets of conjoined twins with no mortality related to the separation, although 1 of the first twins had significant cardiac and respiratory abnormalities and died several years after the separation...
February 2, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29399953/history-and-highlights-of-the-teratological-collection-in-the-museum-anatomicum-of-leiden-university-the-netherlands
#9
Lucas L Boer, Peter L J Boek, Andries J van Dam, Roelof-Jan Oostra
The anatomical collection of the Anatomical Museum of Leiden University Medical Center (historically referred to as Museum Anatomicum Academiae Lugduno-Batavae) houses and maintains more than 13,000 unique anatomical, pathological and zoological specimens, and include the oldest teratological specimens of The Netherlands. Throughout four centuries hundreds of teratological specimens were acquired by more than a dozen collectors. Due to the rich history of this vast collection, teratological specimens can be investigated in a unique retrospective sight going back almost four centuries...
March 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29375901/conjoined-twins-role-of-imaging-and-recent-advances
#10
Rishi Philip Mathew, Swati Francis, Ram Shenoy Basti, Hadihally B Suresh, Annie Rajarathnam, Prema D Cunha, Sujaya V Rao
Introduction: Conjoined twins are identical twins with fused bodies, joined in utero. They are rare complications of monochorionic twinning. The purpose of this study is to describe the various types of conjoined twins, the role of imaging and recent advances aiding in their management. Material and methods: This was a twin institutional study involving 3 cases of conjoined twins diagnosed over a period of 6 years from 2010 to 2015. All the 3 cases were identified antenatally by ultrasound...
December 2017: Journal of Ultrasonography
https://www.readbyqxmd.com/read/29368903/-anesthesic-management-during-total-organic-separation-of-pygopagus-conjoined-twins
#11
Mayra Lizeth Nava-Martínez, Enriqueta Macias-Miranda, Karla Guadalupe Lozada-Rosete, Juan José Dosta-Herrera
BACKGROUND: Conjoined twins are among the most rare and challenging congenital malformations. The incidence varies from 1:30 000 to 1:200 000 live births. Pygopagus twins account for about 10 to 18% of all conjoined twins. CLINICAL CASE: We report the case of male conjoined pygopagus twins. They shared medullary canal, anal canal and sacrococcygeal region, without any degree of cross circulation. At the moment of the surgery, twin 1 had congenital heart disease without medical treatment...
January 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29321278/spemann-mangold-grafts
#12
Hélène Cousin
In 1924, Hans Spemann and Hilde Mangold (née Pröscholdt) published their famous work describing the transplantation of dorsal blastopore lip of one newt gastrula embryo onto the ventral side of a host embryo at the same stage. They performed these grafts using two newt species with different pigmentation ( Triturus taeniatus and Triturus cristatus ) to follow the fate of the grafted tissue. These experiments resulted in the development of conjoined twins attached through their belly. Because of the difference in embryo pigmentation between the two Triturus species, they determined that the bulk of the secondary embryo arose from the host embryo while the grafted tissue per se gave increase to the notochord and a few somitic cells...
January 10, 2018: Cold Spring Harbor Protocols
https://www.readbyqxmd.com/read/29248882/-mutiny-on-the-crown-two-cases-of-rare-cephalic-malformations
#13
Kashish Khanna, Minu Bajpai, Alisha Gupta, Prabudh Goel
The presentation and management of two bizarre congenital cephalic curiosities at the two extremes of the clinical spectrum are discussed herewith. Case 1: presented to us as a neonate with a scalp swelling mirror-imaging her head and face. The journey from clinics to wards and to the operation theatre and to her home is introspected. Case 2: presented to us as dicephalous dibrachius dipus parapagus conjoined twins. The detailed work-up of individual organ systems, the multidisciplinary approach to management and the final outcome are discussed...
December 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29103407/musical-interests-and-talent-twin-jazz-musicians-and-twin-studies-twin-research-loss-of-a-preterm-multiple-conjoined-twin-conception-depression-in-fathers-of-twins-twin-to-twin-transfusion-syndrome-twin-news-high-achieving-twins-twin-children-of-a-tennis-star
#14
Nancy L Segal
Findings from twin studies of musical interests and talent are reviewed as a backdrop to the lives and careers of twin jazz musicians, Peter and Will Anderson. The Anderson twins exemplify many aspects of twin research, namely their matched musical abilities, shared musical interests, and common career. This overview is followed by reviews of studies and case reports of bereavement in families who have lost a preterm multiple birth infant, the conception of conjoined twins following in vitro fertilization (IVF), depression in fathers of twins, and twin-to-twin transfusion incidence in monochorionic-diamniotic IVF twin pairs...
December 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29065049/bioinformatics-associated-with-conjoined-twin-separation
#15
Sarah Jane Commander, Samantha J Jacques, Mark S Lloyd, Audra Rushing, Helena Karlberg, Edward P Buchanan
The separation of conjoined twins is a rare event in the medical field and presents many unique challenges to overcome. With the complexities of today's interconnected healthcare technology and electronic medical record, there are many intricate details that need significant attention to guarantee proper care and accurate record keeping for conjoined twins. Items that require attention are how to digitally represent the twins-as 1 patient or 2, how to incorporate the physiological monitors into the medical record, and how to ensure the proper amount of infrastructure, equipment, and space...
January 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29064095/prenatal-sonographic-diagnosis-of-cephalopagus-conjoined-twins-at-14-weeks-of-pregnancy
#16
Serenat Eris Yalcin, Mehmet Ozgur Akkurt, And Yavuz, Yakup Yalcin, Mekin Sezik
Conjoined twins are extremely rare and are a type of monozygotic twins that occur due to an incomplete embryonic division on postconception day 13 to 15. Eight different types of conjoined twins have been described in the literature. Management of the condition depends on the site and extent of the union. We present a case of cephalopagus twins diagnosed at 14 weeks of gestation.
October 24, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29057694/early-unexpected-diagnosis-of-fetal-life-limiting-malformation-antenatal-palliative-care-and-parental-decision
#17
Federico Mariona, Marianne Burnett, Melody Zoma, Janice Blake, Hanna Khouri
INTRODUCTION: Conjoined twins are an infrequent occurrence in obstetric practice. Live-conjoined twins on a late preterm triplet pregnancy is an even rarer event. OBJECTIVE: The objective of this study is to emphasize the critical importance of perinatal palliative care and non-directive parental counseling, informed decision making and respect for autonomy following full disclosure of findings, fetal life-limiting diagnosis, treatment alternatives, maternal-fetal potential complications, and most likely perinatal outcomes...
November 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29033752/anesthetic-management-of-craniopagus-conjoined-twins-in-a-remote-location
#18
Monu Yadav, Ramakrishnaprasad Chikkala, Dilip Kulkarni, R Gopinath
No abstract text is available yet for this article.
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28940234/canine-conjoined-twinning-a-pathoanatomical-study-of-a-lhasa-apso-symmetrical-cephalothoracopagus
#19
E Moura, B Thon, C T Pimpão
A female pair of conjoined twins of the Lhasa Apso canine breed was subjected to tomographic and anatomical examinations. The twins had only one head and neck. The two ribcages were joined, extending to the umbilicus, with duplicated structures thereafter. They had three thoracic limbs and two pelvic girdles with four limbs, as well as a number of abnormalities in their internal organs. The data obtained were compared with the rare canine cases reported so far and with human cases.
September 20, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28938130/learning-in-the-machine-the-symmetries-of-the-deep-learning-channel
#20
Pierre Baldi, Peter Sadowski, Zhiqin Lu
In a physical neural system, learning rules must be local both in space and time. In order for learning to occur, non-local information must be communicated to the deep synapses through a communication channel, the deep learning channel. We identify several possible architectures for this learning channel (Bidirectional, Conjoined, Twin, Distinct) and six symmetry challenges: (1) symmetry of architectures; (2) symmetry of weights; (3) symmetry of neurons; (4) symmetry of derivatives; (5) symmetry of processing; and (6) symmetry of learning rules...
November 2017: Neural Networks: the Official Journal of the International Neural Network Society
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