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Jesús M López, Lorena Morales, Agustín González
The present immunohistochemical study represents a detailed spatiotemporal analysis of the localization of orexin-immunoreactive (OX-ir) cells and fibers throughout development in the brain of the anuran amphibian Xenopus laevis, a model frequently used in developmental studies. Anurans undergo remarkable physiological changes during the early life stages, and very little is known about the ontogeny and the localization of the centers that control functions such as appetite and feed ingestion in the developing brain...
October 22, 2016: Brain, Behavior and Evolution
Laleh Majari Kasmaee, Asghar Aryanfar, Zarui Chikneyan, Michael R Hoffmann, Agustín J Colussi
Understanding the mechanism of formation of solid-electrolyte interphases (SEI) is key to the prospects of lithium metal batteries (LMB). Here, we investigate via cyclic voltammetry, impedance spectroscopy and chronoamperometry the role of kinetics in controlling the properties of the SEI generated from the reduction of propylene carbonate (PC, a typical solvent in LMB). Our observations are consistent with the operation of a radical chain PC electropolymerization into polymer units whose complexity increases at lower initiation rates...
September 16, 2016: Chemical Physics Letters
Agustin Ramirez
The presentation will focus on the different guidelines we have actually in hands (JNCHT 8, ESH / ESC, ISH) and compare them to the last Latin-American Society of Hypertension Guidelines to be published in this year.In this way, we will focus our attention in the socio-economic problem of the different countries in LA and the differences we have included in our Guidelines due to the actual needs in LA.Additionally we will specially mention the special populations from LA like andineans, people living over 500m from sea level, and the different black populations that are different from those described in North America...
September 2016: Journal of Hypertension
Virginia Almadana Pacheco, Ana Paulina Gómez-Bastero Fernández, Agustín Valido Morales, Estefanía Luque Crespo, Soledad Monserrat, Teodoro Montemayor Rubio
: There is evidence of the relationship between mental illness and smoking and increased risk of depressive episodes after quitting smoking, even with specific treatments for abstinence. OBJECTIVE: To assess the influence of a cessation program on the emotional state of patients by measuring levels of anxiety / depression and differences depending on the presence of psychiatric history. METHOD: A prospective observational study of patients taking part in a combined program (pharmacological and cognitive-behavioral) for giving up smoking...
October 7, 2016: Adicciones
Rebecca Z Krouse, Christine A Sorkness, Jeremy J Wildfire, Agustin Calatroni, Rebecca Gruchalla, Gurjit K Khurana Hershey, Meyer Kattan, Andrew H Liu, Melanie Makhija, Stephen J Teach, Joseph B West, Robert A Wood, Edward M Zoratti, Peter J Gergen
CASI is a quantitative measure of asthma severity that was introduced in the Journal of Allergy and Clinical Immunology in March 2012. This follow-up letter expands upon the initial report by comparing the CASI to an expert clinican assessment of asthma severity. Using expert assessment, we establish risk levels for CASI and calculate other useful parameters such as the minimal important difference (MID) and minimal important effect size.
October 12, 2016: Journal of Allergy and Clinical Immunology
Nayeli Rivera-Ramírez, Wilber Montejo-López, María-Cristina López-Méndez, Agustín Guerrero-Hernández, Anayansi Molina-Hernández, Ubaldo García-Hernández, José-Antonio Arias-Montaño
The histamine H3 receptor (H3R) is abundantly expressed in the Central Nervous System where it regulates several functions pre and postsynaptically. H3Rs couple to Gαi/o proteins and trigger or modulate several intracellular signaling pathways, including the cAMP/PKA pathway and the opening of N- and P/Q-type voltage-gated Ca(2+) channels. In transfected cells, activation of the human H3R of 445 amino acids (hH3R445) results in phospholipase C (PLC) stimulation and release of Ca(2+) from intracellular stores...
October 12, 2016: Neurochemistry International
Juan Luis Blas Laina, Yurema González Ruiz, Elena Gonzalvo González, María Pilar Sanz Moncasi, Agustín Rodríguez Borobia
No abstract text is available yet for this article.
October 12, 2016: Gastroenterología y Hepatología
Jan J W A Boei, Sylvia Vermeulen, Binie Klein, Pieter S Hiemstra, Renate M Verhoosel, Danyel G J Jennen, Agustin Lahoz, Hans Gmuender, Harry Vrieling
Differentiated human bronchial epithelial cells in air liquid interface cultures (ALI-PBEC) represent a promising alternative for inhalation studies with rodents as these 3D airway epithelial tissue cultures recapitulate the human airway in multiple aspects, including morphology, cell type composition, gene expression and xenobiotic metabolism. We performed a detailed longitudinal gene expression analysis during the differentiation of submerged primary human bronchial epithelial cells into ALI-PBEC to assess the reproducibility and inter-individual variability of changes in transcriptional activity during this process...
October 13, 2016: Archives of Toxicology
Victor B Arias, Daniel E Nuñez, Agustín Martínez-Molina, Fernando P Ponce, Benito Arias
The Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnostic criteria assume that the 18 symptoms carry the same weight in an Attention Deficit with Hyperactivity Disorder (ADHD) diagnosis and bear the same discriminatory capacity. However, it is reasonable to think that symptoms may differ in terms of severity and even in the reliability with they represent the disorder. To test this hypothesis, the aim of this study was to calibrate in a sample of Spanish children (age 4-7; n = 784) a scale for assessing the symptoms of ADHD proposed by Diagnostic and Statistical Manual of Mental Disorders, IV-TR within the framework of Item Response Theory...
2016: PloS One
Thalita Dallapícula Ramos, Ricardo J Cassella, Miguel de la Guardia, Agustín Pastor, Francesc A Esteve-Turrillas
The versatile, easy, and rapid atmospheric monitor (VERAM), a passive sampler device widely used for air monitoring, was evaluated as passive sampler for the determination of 23 pesticides in water. Gas chromatography with mass spectrometry detection was employed for determination of pesticides after microwave-assisted-extraction and specific clean-up of deployed samplers. The proposed methodology reached method detection levels from 2 to 10 ng pesticide per sampler. Sampling rate (Rs) was determined for every pesticide from an uptake isotherm study performed at three different concentration levels (50, 125, and 250 ng L(-1))...
October 12, 2016: Analytical and Bioanalytical Chemistry
Andrew M Wright, Agustin Zapata, Michael H Baumann, Joshua S Elmore, Alexander F Hoffman, Carl R Lupica
Clinical descriptions of cocaine addiction include compulsive drug seeking and maladaptive decision-making despite substantial aversive consequences. Research suggests that this may result from altered orbitofrontal cortex (OFC) function and its participation in outcome-based behavior. Clinical and animal studies also implicate serotonin in the regulation of OFC function in addiction and other neuropsychiatric disorders. Here we test the hypothesis that exposure to cocaine, through self-administration (CSA) or yoked-administration (CYA), alters the regulation of OFC function by 5-HT...
October 12, 2016: Cerebral Cortex
Marlène Dupraz, Céline Toty, Valérie Noël, Agustin Estrada-Peňa, Jacob González-Solís, Thierry Boulinier, Jean-Pierre Dujardin, Karen D McCoy
Host specific adaptations in parasites can lead to the divergence of conspecific populations. However, this divergence can be difficult to measure because morphological changes may not be expressed or because obvious changes may simply reflect phenotypic plasticity. Combining both genetic and phenotypic information can enable a better understanding of the divergence process and help identify the underlying selective forces, particularly in closely-related species groups. Here, we link genetic and morphometric data to understand divergence patterns within the Ornithodoros (Carios) capensis complex, a group of soft ticks (Argasidae) exploiting colonial seabirds across the globe...
October 8, 2016: Infection, Genetics and Evolution
Aline Priscila Ataíde, Felipe Paiva Fonseca, Alan Roger Santos Silva, Jacks Jorge Júnior, Márcio Ajudarte Lopes, Pablo Agustin Vargas
OBJECTIVES: Oral lesions affecting infants account for approximately 10% of all samples from diagnostic services and studies investigating the distribution of these lesions in pediatrics from different geographic areas are desired to improve the diagnostic knowledge of clinicians. Therefore, the aim of this study is to describe the distribution of oral lesions in a southeastern Brazilian population. METHODS: The oral pathology files of the University of Campinas was retrospectively reviewed for all cases diagnosed from 2000 to 2014 affecting patients 16-years-old and younger...
November 2016: International Journal of Pediatric Otorhinolaryngology
Paula J Busse, Janette M Birmingham, Agustin Calatroni, Joseph Manzi, Anna Goryachokovsky, Giselle Fontela, Alex Federman, Juan Wisnivesky
BACKGROUND: Aged asthma patients experience increased morbidity and mortality. Knowledge of the aging effect on airway inflammation and asthma control is limited. OBJECTIVE: To compare airway inflammation and its relationship with asthma control in aged vs. younger patients and determine if differences are asthma-specific or due to "inflamm-aging." METHODS: Prospective study of aged (>60 years) and younger (21-40 years) inner-city asthma patients...
October 7, 2016: Journal of Allergy and Clinical Immunology
Valeria C Colombo, Leandro R Antoniazzi, Agustín A Fasano, Pablo M Beldomenico, Santiago Nava
The aim of this communication is to report, for the first time, the occurrence of Amblyomma triste in Santa Fe province, Argentina, and to add a new isolation place for Amblyomma tigrinum. Both species of ticks are vectors of Rickettsia parkeri, a spotted fever group rickettsia. Ticks were recovered from tourists in August 2014 and December 2015 at the Federico Wildermuth Foundation (31° 59'S, 61° 24'O), San Martin Department, Santa Fe province. Five adult ticks were morphologically identified as A. tigrinum (3 females and 1 male) and A...
2016: Medicina
Laura Martínez-Rodríguez, Javier Estañ, Jose D Bermudez, Agustin Molina, Veronica Hortelano, Cecilia Martinez-Costa
No abstract text is available yet for this article.
October 7, 2016: Early Human Development
Leandro Castañeyra-Ruiz, Ibrahim González-Marrero, Luis G Hernández-Abad, Emilia M Carmona-Calero, Gundela Meyer, Agustín Castañeyra-Perdomo
The choroid plexuses (ChP) are highly vascularized tissues suspended from each of the cerebral ventricles. Their main function is to secret cerebrospinal fluid (CSF) that fills the ventricles and the subarachnoid spaces, forming a crucial system for the development and maintenance of the CNS. However, despite the essential role of the ChP-CSF system to regulate the CNS in a global manner, it still remains one of the most understudied areas in neurobiology. Here we define by immunohistochemistry the expression of different proteins involved in the maturation and functionality of the ChP from the late embryological period to maturity...
2016: Frontiers in Neuroanatomy
Cesar García-Hernández, Javier Arece-García, Rolando Rojo-Rubio, German David Mendoza-Martínez, Benito Albarrán-Portillo, José Fernando Vázquez-Armijo, Leonel Avendaño-Reyes, Agustín Olmedo-Juárez, Carine Marie-Magdeleine, Yoel López-Leyva
Forty-five Pelibuey sheep were experimentally infested with nematodes to evaluate the effect of three free condensed tannin (FCT) levels of Lysiloma acapulcensis on fecal egg counts (FECs), packed cell volumes (PCV), ocular mucosa colors (OMC), average daily gain (ADG), and adult nematode count. Five treatments were used: 12.5, 25.0, and 37.5 mg of FCT kg(-1) of body weight (BW); sterile water (control); and ivermectine (0.22 mg kg(-1) of BW) as chemical group. The data were processed through repeated measurement analysis...
October 7, 2016: Tropical Animal Health and Production
Sofía P Brandariz, Agustín González Reymúndez, Bettina Lado, Marcos Malosetti, Antonio Augusto Franco Garcia, Martín Quincke, Jarislav von Zitzewitz, Marina Castro, Iván Matus, Alejandro Del Pozo, Ariel J Castro, Lucía Gutiérrez
BACKGROUND: Whole-genome genotyping techniques like Genotyping-by-sequencing (GBS) are being used for genetic studies such as Genome-Wide Association (GWAS) and Genomewide Selection (GS), where different strategies for imputation have been developed. Nevertheless, imputation error may lead to poor performance (i.e. smaller power or higher false positive rate) when complete data is not required as it is for GWAS, and each marker is taken at a time. The aim of this study was to compare the performance of GWAS analysis for Quantitative Trait Loci (QTL) of major and minor effect using different imputation methods when no reference panel is available in a wheat GBS panel...
October 4, 2016: BMC Genomics
Emilia Matallana, Agustín Aranda
Wine yeast deals with many stress conditions during its biotechnological use. Biomass production and its dehydration produce major oxidative stress, while hyperosmotic shock, ethanol toxicity and starvation are relevant during grape juice fermentation. Most stress response mechanisms described in laboratory strains of Saccharomyces cerevisiae are useful for understanding the molecular machinery devoted to deal with harsh conditions during industrial wine yeast uses. However, the particularities of these strains themselves, and the media and conditions employed, need to be specifically looked at when studying protection mechanisms...
October 7, 2016: Letters in Applied Microbiology
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