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https://www.readbyqxmd.com/read/29229797/capturing-the-flow-beneath-water-waves
#1
REVIEW
A Nachbin, R Ribeiro-Junior
Recently, the authors presented two numerical studies for capturing the flow structure beneath water waves (Nachbin and Ribeiro-Junior 2014 Disc. Cont. Dyn. Syst. A34, 3135-3153 (doi:10.3934/dcds.2014.34.3135); Ribeiro-Junior et al. 2017 J. Fluid Mech.812, 792-814 (doi:10.1017/jfm.2016.820)). Closed orbits for irrotational waves with an opposing current and stagnation points for rotational waves were some of the issues addressed. This paper summarizes the numerical strategies adopted for capturing the flow beneath irrotational and rotational water waves...
January 28, 2018: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29222766/electrical-velocimetry-for-non-invasive-monitoring-of-the-closure-of-the-ductus-arteriosus-in-preterm-infants
#2
Ana Rodríguez Sánchez de la Blanca, M Sánchez Luna, N González Pacheco, M Arriaga Redondo, N Navarro Patiño
Closure of a patent ductus arteriosus (PDA) in preterm infants modifies cardiac output and induces adaptive changes in the hemodynamic situation. The present study aims to analyze those changes, through a non-invasive cardiac output monitor based on blood electrical velocimetry, in preterm babies. A prospective observational study of preterm infants with a gestational age of less than 28 weeks, and a hemodynamic significant PDA, requires intravenous ibuprofen or surgical closure. All patients were monitored with electrical velocimetry before treatment and through the following 72 h...
December 8, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29204456/erratum-publisher-s-note-enzyme-transient-state-kinetics-in-crystal-and-solution-from-the-perspective-of-a-time-resolved-crystallographer-struct-dyn-1-024701-2014
#3
Marius Schmidt, Dilano K Saldin
[This corrects the article DOI: 10.1063/1.4869472.].
November 2017: Structural Dynamics (Melville, N.Y.)
https://www.readbyqxmd.com/read/29203229/effects-on-hedonic-feeding-energy-expenditure-and-balance-of-the-non-opioid-peptide-dyn-a2-17
#4
B Alvarez, T Barrientos, L Gac, J A Teske, C E Perez-Leighton
The dynorphin (DYN) peptide family includes opioid and non-opioid peptides, yet the physiological role of the non-opioid DYN peptides remains poorly understood. Recent evidence shows that administering the non-opioid peptide DYN-A2-17 into the paraventricular hypothalamic nucleus (PVN) simultaneously increased short-term intake of standard rodent chow and spontaneous physical activity (SPA). The present studies aimed to expand upon the mechanisms and role of DYN-A2-17 on food intake and energy expenditure. Injection of DYN-A2-17 in PVN increased SPA, energy expenditure and wheel running in the absence of food...
December 1, 2017: Neuroscience
https://www.readbyqxmd.com/read/29200842/hemodynamic-and-gas-exchange-effects-of-inhaled-iloprost-in-patients-with-copd-and-pulmonary-hypertension
#5
Lan Wang, Yuan-Zhe Jin, Qin-Hua Zhao, Rong Jiang, Wen-Hui Wu, Su-Gang Gong, Jing He, Jin-Ming Liu, Zhi-Cheng Jing
Studies have shown that vasodilators such as iloprost can be useful for treating pulmonary hypertension (PH). However, in patients with COPD, vasodilators may inhibit hypoxic pulmonary vasoconstriction and impair gas exchange. The efficacy and safety of iloprost inhalation was assessed in 67 patients with PH associated with COPD (COPD-PH), diagnosed by right heart catheterization. Of these, 37 patients had severe PH (mean pulmonary arterial pressure [mPAP] >35 mmHg or mPAP 25-35 mmHg with low cardiac index [<2...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29190756/visualizing-the-spatiotemporal-map-of-rac-activation-in-bovine-aortic-endothelial-cells-under-laminar-and-disturbed-flows
#6
Shuai Shao, Cheng Xiang, Kairong Qin, Aziz Ur Rehman Aziz, Xiaoling Liao, Bo Liu
Disturbed flow can eliminate the alignment of endothelial cells in the direction of laminar flow, and significantly impacts on atherosclerosis in collateral arteries near the bifurcation and high curvature regions. While shear stress induced Rac polarity has been shown to play crucial roles in cell polarity and migration, little is known about the spatiotemporal map of Rac under disturbed flow, and the mechanism of flow-induced cell polarity still needs to be elucidated. In this paper, disturbed flow or laminar flow with 15 dyn/cm2 of average shear stress was applied on bovine aortic endothelial cells (BAECs) for 30 minutes...
2017: PloS One
https://www.readbyqxmd.com/read/29187777/comments-on-coexistence-of-hidden-chaotic-attractors-in-a-novel-no-equilibrium-system-nonlinear-dyn-doi-10-1007-s11071-016-3170-x
#7
REVIEW
Ivo Petráš
In this comment, an enhancement of issue published in the paper "Coexistence of hidden chaotic attractors in a novel no-equilibrium system" (Nonlinear Dyn, doi:10.1007/s11071-016-3170-x) is addressed. We have shown that the proposed novel autonomous chaotic system can be extended to its fractional-order version where hidden attractors as well as other dynamical properties of the new no-equilibrium system can be observed. A created MATLAB function for the new fractional-order no-equilibrium system is also presented...
2017: Nonlinear Dynamics
https://www.readbyqxmd.com/read/29187198/preliminary-reference-intervals-and-the-impact-of-citrate-storage-time-for-thrombelastography-in-cats-including-delta-and-the-velocity-curve
#8
Carolin Engelen, Andreas Moritz, Franziska Barthel, Natali Bauer
BACKGROUND: Thrombelastography is a useful tool in assessment of hemostasis. Beside the traditional variables, the velocity curve and the variable delta have lately earned attention. The velocity curve provides knowledge about the speed of clot formation including information about thrombin generation. Delta, which only reflects enzymatic coagulation, allows the determination of the origin of hypercoagulability when compared to clot rigidity, a variable that reflects both platelet and enzymatic activity...
November 29, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29126680/anesthetic-and-perioperative-considerations-for-combined-heart-kidney-transplantation
#9
Santiago Mc Loughlin, Juan C Bianco, Ricardo G Marenchino
OBJECTIVE: To describe detailed perioperative features of combined heart and kidney transplant (HKT). DESIGN: Retrospective study. SETTING: Tertiary care university hospital. PARTICIPANTS: All consecutive HKT recipients aged 18 years and older. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: After approval of the Institutional Review Board, the authors studied all consecutive adult patients who underwent HKT between January 2013 and July 2016...
September 15, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29112103/vasopressin-in-vasodilatory-shock-for-both-left-and-right-heart-anomalous-pediatric-patients-after-cardiac-surgery
#10
Zhongyuan Lu, Xu Wang, Juxian Yang, Shoujun Li, Jun Yan
Although the use of vasopressin has become common place in pediatric patients with vasodilatory shock after cardiac surgery, its efficacy and hemodynamic effects have not been systematically documented. Furthermore, previous studies were mainly limited patients with left heart anomalies. To date, the use of vasopressin in patients with right heart anomalies hasn't yet been reported. To clarify the hemodynamic effects of vasopressin on pediatric patients with vasodilatory shock after cardiopulmonary bypass, 70 consecutive patients, most of whom with right heart anomalies were retrospectively analyzed in Fuwai Hospital from October 2013 to September 2015...
November 3, 2017: Shock
https://www.readbyqxmd.com/read/29058488/evaluation-of-different-metrics-as-an-index-for-the-assessment-of-arterial-stiffness
#11
Camille Leblanc, Hilary R Strong, Reza Tabrizchi
Elevated intravascular pressure is a contributing factor to increased arterial stiffness, and is a risk factor for cardiovascular morbidity and mortality. Assessment of arterial stiffness is of importance in evaluating cardiovascular risk. Pulse wave velocity (PWV) has been broadly used in the assessment of arterial stiffness. We compared three different metrics of arterial stiffness to PWV. Hemodynamic recordings were carried out in anesthetized hypertensive and normotensive rats (n = 25; 13-14 weeks old)...
October 23, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29052842/shear-stress-upregulates-regeneration-related-immediate-early-genes-in-liver-progenitors-in-3d-ecm-like-microenvironments
#12
Kenichiro Nishii, Erik Brodin, Taylor Renshaw, Rachael Weesner, Emma Moran, Shay Soker, Jessica L Sparks
The role of fluid stresses in activating the hepatic stem/progenitor cell regenerative response is not well understood. This study hypothesized that immediate early genes (IEGs) with known links to liver regeneration will be upregulated in liver progenitor cells (LPCs) exposed to in vitro shear stresses on the order of those produced from elevated interstitial flow after partial hepatectomy. The objectives were: (1) to develop a shear flow chamber for application of fluid stress to LPCs in 3D culture; and (2) to determine the effects of fluid stress on IEG expression in LPCs...
October 20, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29052613/dynorphin-counteracts-orexin-in-the-paraventricular-nucleus-of-the-thalamus-cellular-and-behavioral-evidence
#13
Alessandra Matzeu, Marsida Kallupi, Olivier George, Paul Schweitzer, Rémi Martin-Fardon
The orexin (Orx) system plays a critical role in drug addiction and reward-related behaviors. The dynorphin (Dyn) system promotes depressive-like behavior and plays a key role in the aversive effects of stress. Orx and Dyn are co-released and have opposing functions in reward and motivation in the ventral tegmental area (VTA). Previous studies suggested that OrxA transmission in the posterior paraventricular nucleus of the thalamus (pPVT) participates in cocaine-seeking behavior. This study determined whether Orx and Dyn interact in the pPVT...
October 20, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29023796/hemodynamic-parameters-and-baroreflex-sensitivity-during-head-up-tilt-test-in-patients-with-neurally-mediated-syncope
#14
Sung Ho Lee, Ji Hyun Yang, Hye Ran Yim, Jungwae Park, Seung-Jung Park, Kyoung-Min Park, Young Keun On, June Soo Kim
BACKGROUND: We aimed to investigate differences in hemodynamic parameters and the role of baroreflex sensitivity (BRS) in patients with a history of neurally mediated syncope (NMS) compared with a control group. METHODS: Hemodynamic parameters and BRS were continuously measured non-invasively using a Finometer at rest and during passive head-up tilt test (HUT) in patients with a history of NMS (n = 55) and a control group (n = 77). The tilting period was divided into pretest (resting supine position), initial (first 3 minutes of tilting), last (last 3 minutes of tilting), and recovery (3 minutes after tilting was complete) periods...
October 10, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28983180/positive-solutions-of-fractional-integral-equations-by-the-technique-of-measure-of-noncompactness
#15
Hemant Kumar Nashine, Reza Arab, Ravi P Agarwal, Manuel De la Sen
In the present study, we work on the problem of the existence of positive solutions of fractional integral equations by means of measures of noncompactness in association with Darbo's fixed point theorem. To achieve the goal, we first establish new fixed point theorems using a new contractive condition of the measure of noncompactness in Banach spaces. By doing this we generalize Darbo's fixed point theorem along with some recent results of (Aghajani et al. (J. Comput. Appl. Math. 260:67-77, 2014)), (Aghajani et al...
2017: Journal of Inequalities and Applications
https://www.readbyqxmd.com/read/28979628/determination-in-vivo-viability-of-a-transfused-platelet-product-by-corrected-count-increment-and-percentage-platelet-response
#16
Nancy Wanjiru Thuku, Kibet Shikuku, Amos Mbugua
INTRODUCTION: For many years, platelet concentrates have been used for the prevention as well as treatment of bleeding disorders, especially in those patients with haematological problems involving platelet disorders as well as refractoriness, In addition, platelet concentrates (PCs) have been widely used to support patients undergoing bone marrow transplantation or who are receiving myelotoxic treatments. The aim of this study was to determine the quality of platelet concentrates by assessing platelet counts, volume, pH changes, swirling, residue of the red blood cells and white blood cell counts...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28975714/comparing-the-performance-of-three-panels-rules-of-blood-smear-review-criteria-on-an-italian-multicenter-evaluation
#17
S Pipitone, L Germagnoli, G Da Rin, A Di Fabio, A Fanelli, F Fiorini, S Francione, A Marini, A Papa, A Benegiamo, T Lari, F Siviero, M Lorubbio, M Borin, M Seghezzi, M L Ciardelli, F Dima, M Gioia, S Buoro
BACKGROUND: The aims of this study were to compare the diagnostic accuracy of blood smear review criteria, by means of three different panel rules, those proposed by: the International Consensus Group for Hematology [41-ICGH rules], the Italian Survey [IS rules] and the Working Group on Hematology-SIBioC (WGH) consensus rules (WGH rules). METHODS: This study is based on 2707 peripheral blood (PB) samples referred for routine hematological testing to the WGH-associated laboratories displaced all over the Italian territory...
October 3, 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28949623/global-method-for-electron-correlation
#18
Mario Piris
The current work presents a new single-reference method for capturing at the same time the static and dynamic electron correlation. The starting point is a determinant wave function formed with natural orbitals obtained from a new interacting-pair model. The latter leads to a natural orbital functional (NOF) capable of recovering the complete intrapair, but only the static interpair correlation. Using the solution of the NOF, two new energy functionals are defined for both dynamic (E^{dyn}) and static (E^{sta}) correlation...
August 11, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28938829/point-to-set-dynamic-length-scale-in-binary-lennard-jones-glass-formers
#19
Baicheng Mei, Zhenhua Wang, Yuyuan Lu, Hongfei Li, Lijia An
Our recent molecular dynamics simulation results of binary particle glass-former systems demonstrated that the non-monotonic temperature T-dependence of the point-to-set dynamic length scale ξc(dyn) in harmonic (HM) systems is not an intrinsic property of bulk liquids but originates from wall effects. We would expect our results to apply equally to other simple models, such as Lennard-Jones (LJ) systems. However, Hocky et al. presented a monotonic T-dependent ξc(dyn) in a LJ system. Therefore, the present work employs molecular dynamics simulations to investigate the T-dependent behavior of ξc(dyn) in the LJ system employed by Hocky et al...
September 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28919201/macitentan-for-the-treatment-of-inoperable-chronic-thromboembolic-pulmonary-hypertension-merit-1-results-from-the-multicentre-phase-2-randomised-double-blind-placebo-controlled-study
#20
Hossein-Ardeschir Ghofrani, Gérald Simonneau, Andrea M D'Armini, Peter Fedullo, Luke S Howard, Xavier Jaïs, David P Jenkins, Zhi-Cheng Jing, Michael M Madani, Nicolas Martin, Eckhard Mayer, Kelly Papadakis, Dominik Richard, Nick H Kim
BACKGROUND: Macitentan is beneficial for long-term treatment of pulmonary arterial hypertension. The microvasculopathy of chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension are similar. METHODS: The phase 2, double-blind, randomised, placebo-controlled MERIT-1 trial assessed macitentan in 80 patients with CTEPH adjudicated as inoperable. Patients identified as WHO functional class II-IV with a pulmonary vascular resistance (PVR) of at least 400 dyn·s/cm(5) and a walk distance of 150-450 m in 6 min were randomly assigned (1:1), via an interactive voice/web response system, to receive oral macitentan (10 mg once a day) or placebo...
October 2017: Lancet Respiratory Medicine
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