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https://www.readbyqxmd.com/read/29906700/patient-characteristics-and-treatment-patterns-in-patients-with-newly-diagnosed-epilepsy-a-us-database-analysis
#1
Edward Faught, Sandra Helmers, David Thurman, Hyunmi Kim, Linda Kalilani
OBJECTIVE: The objective of this study was to determine patient characteristics and antiepileptic drug (AED) treatment patterns in patients with newly diagnosed epilepsy in a United States (US) population followed for ≥180 days. METHODS: In this retrospective cohort study, Commercial, Supplemental Medicare, and Medicaid insurance claims from US-based Truven Health MarketScan® claims database were analyzed for incident epilepsy cases (index date: January 2010-June 2013; prior baseline of 2 years [1 year for ages 1 to <2 years; none for those <1 year])...
June 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29904156/contrasting-effectiveness-and-cost-effectiveness-of-colorectal-cancer-screening-under-commercial-insurance-vs-medicare
#2
Uri Ladabaum, Ajitha Mannalithara, Joel V Brill, Zachary Levin, M Kate Bundorf
OBJECTIVES: Most cost-effectiveness analyses of colorectal cancer (CRC) screening assume Medicare payment rates and a lifetime horizon. Our aims were to examine the implications of differential payment levels and time horizons for commercial insurers vs. Medicare on the cost-effectiveness of CRC screening. METHODS: We used our validated Markov cohort simulation of CRC screening in the average risk US population to examine CRC screening at ages 50-64 under commercial insurance, and at ages 65-80 under Medicare, using a health-care sector perspective...
June 15, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29903000/assessing-out-of-pocket-expenditures-for-primary-health-care-how-responsive-is-the-democratic-republic-of-congo-health-system-to-providing-financial-risk-protection
#3
Samia Laokri, Rieza Soelaeman, David R Hotchkiss
BACKGROUND: The goal of universal health coverage is challenging for chronically under-resourced health systems. Although household out-of-pocket payments are the most important source of health financing in low-income countries, relatively little is known about the drivers of primary health care expenditure and the predictability of the burden associated with high fee-for-service payments. This study describes out-of-pocket health expenditure and investigates demand- and supply-side drivers of excessive costs in the Democratic Republic of Congo (DRC), a central African country in the midst of a process of reforming its health financing system towards universal health coverage...
June 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29902309/risk-factors-for-corrective-septorhinoplasty-associated-with-initial-treatment-of-isolated-nasal-fracture
#4
Kevin Li, Sami P Moubayed, Emily Spataro, Sam P Most
Importance: Initial treatment of nasal fractures can result in long-standing cosmetic or functional defects, but the risk factors for subsequent septorhinoplasty have not been explored. Objective: To assess the risk factors for septorhinoplasty after the initial treatment of isolated nasal fracture. Design, Setting, and Participants: This retrospective population-based analysis of US patients diagnosed with nasal fracture between January 1, 2007, and December 31, 2015, used insurance claims data from the Commercial and Medicare Supplemental categories of the Truven Health MarketScan database...
June 14, 2018: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29901745/patient-features-and-survival-of-pediatric-aplastic-anemia-in-the-usa-a-large-institution-experience
#5
M J Hossain, S Xie
Background: We performed the first epidemiologic investigation to examine association of demographics and clinical characteristics at diagnosis, as well as health care expense coverage, with survival of US children with aplastic anemia (AA). Methods: We obtained electronic medical record data of 1140 children aged 0-19 years diagnosed with AA followed at a pediatric health system between 2004 and 2014. Kaplan-Meier curve and Cox proportional hazards regressions were used...
June 13, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29890870/economic-burden-work-and-school-productivity-in-individuals-with-tuberous-sclerosis-and-their-families
#6
Anne M Skalicky, Anne M Rentz, Zhimei Liu, Qayyim Said, Jo Anne Nakagawa, Michael D Frost, James W Wheless, David W Dunn
AIMS: Tuberous sclerosis complex (TSC) is a multi-organ autosomal-dominant, genetic disorder with incomplete penetrance. The multiple manifestations of TSC and impacts to numerous organ systems represent significant disease, health care and treatment burden. The economic and employment burden of the disease on individuals and their families is poorly understood. This study assessed the cost of illness and work and school productivity burden associated with TSC in a cross-sectional web-survey sample...
June 11, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29888273/health-related-effects-of-the-elderly-care-program
#7
Young-Eun Kim, Seok-Won Hong
Objectives: This study aimed to determine the health-related effects of elderly care through the elderly program (ECEP) compared to those who were put on standby. Methods: Analysis was conducted concerning the demographic characteristics and chronic disease prevalence status of 108,803 ECEP participants from 2007 to 2013 and 33,932 recipients of elderly care by the elderly (ECE) in 2013. A survey was conducted to determine the effects of emotional support on 508 elders who received ECE in 2014...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29872347/lifetime-risks-loss-of-life-expectancy-and-health-care-expenditures-for-19-types-of-cancer-in-taiwan
#8
Tzu-Yi Wu, Chia-Hua Chung, Chia-Ni Lin, Jing-Shiang Hwang, Jung-Der Wang
Background: The mortality rates for different cancers are no longer an efficient tool for making national policy. The purpose of this study were to quantify the lifetime risks, life expectancies (LEs) after diagnosis, expected years of life lost (EYLL), and lifetime health care expenditures for 19 major cancers in Taiwan. Methods: A total of 831,314 patients with 19 pathologically proven cancers were abstracted from the Taiwan Cancer Registry from 1998 to 2012. They were linked to the National Mortality Registry (1998-2014) and National Health Insurance reimbursement database (1998-2013) for survival and health care costs...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29866616/examination-of-universal-purchase-programs-as-a-driver-of-vaccine-uptake-among-us-states-1995-2014
#9
Karen Mulligan, Julia Thornton Snider, Phyllis Arthur, Gregory Frank, Mahlet Tebeka, Amy Walker, Jason Abrevaya
BACKGROUND: Immunization against numerous potentially life-threatening illnesses has been a great public health achievement. In the United States, the Vaccines for Children (VFC) program has provided vaccines to uninsured and underinsured children since the early 1990s, increasing vaccination rates. In recent years, some states have adopted Universal Purchase (UP) programs with the stated aim of further increasing vaccination rates. Under UP programs, states also purchase vaccines for privately-insured children at federally-contracted VFC prices and bill private health insurers for the vaccines through assessments...
June 1, 2018: Vaccine
https://www.readbyqxmd.com/read/29866596/interferon-gamma-release-assay-based-screening-for-pediatric-latent-tuberculosis-infection-in-an-urban-primary-care-network
#10
James Gaensbauer, Bryn Gonzales, Robert Belknap, Michael L Wilson, Mary E O'Connor
OBJECTIVE: To assess outcomes from a QuantiFERON-tuberculosis (TB) Gold (QFT)-based screening for pediatric latent TB infection (LTBI) in the Denver Health Community Health System (CHS), an urban primary-care network in the US. STUDY DESIGN: We retrospectively analyzed all QFTs (n = 6685) performed on children aged 2-18 years between January 5, 2011, and August 18, 2014. Risk factors for positive testing in the CHS population were identified by logistic regression, and further assessed using a case-control comparison...
June 1, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29865926/the-association-between-adherence-to-levothyroxine-and-economic-and-clinical-outcomes-in-patients-with-hypothyroidism-in-the-us
#11
Zsolt Hepp, Maureen J Lage, Ramon Espaillat, Ved V Gossain
OBJECTIVE: To evaluate outcomes associated with adherence to levothyroxine (LT4) in the US adult hypothyroidism population. METHODS: We used data from Truven's MarketScan databases from July 1, 2011 through December 31, 2015. Patients aged 18 or older were diagnosed with hypothyroidism (confirmed at least twice) and prescribed LT4. Patients were excluded if they did not have continuous insurance coverage or if they received a diagnosis of thyroid cancer or pregnancy during the study period...
June 5, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29863425/effects-of-laparoscopic-surgery-on-survival-quality-of-care-and-utilization-of-patients-with-colon-cancer-a-population-based-study
#12
Elise Chia-Hui Tan, Ming-Chin Yang, Chien-Chih Chen
OBJECTIVE: Laparoscopy is a safe and effective treatment for colon cancer. However, its effects on short- and long-term health outcomes and medical utilization are not fully elucidated. The study aimed to compare short- and long-term utilization and health outcomes of colon cancer patients who underwent either laparoscopic or open surgery in a population-based cohort. METHODS: This study was conducted by linking data from Taiwan Cancer Registry, National Health Insurance claims, and Death Registry...
June 4, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29860373/hepatitis-b-vaccination-and-screening-among-foreign-born-women-of-reproductive-age-in-the-united-states-2013-2015
#13
Greta A Kilmer, Laurie K Barker, Kathleen N Ly, Ruth B Jiles
Background: Mother-to-child transmission of hepatitis B can be prevented with vaccination and screening. Foreign-born women living in the United States may have lower vaccination coverage and greater lifetime exposure to hepatitis B virus than US-born women. Objective: To determine if self-reported hepatitis B vaccination and screening differ between US-born and foreign-born women of reproductive age and examine predictors. Methods: National Health Interview Survey data from 2013-2015 were pooled to estimate prevalence of lifetime history of hepatitis B vaccination and screening self-reported by women aged 18-44 years who were born in the United States or elsewhere (foreign-born)...
June 1, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29858004/rates-of-escalation-to-triple-copd-therapy-among-incident-users-of-lama-and-lama-laba
#14
Beth Hahn, Michael Hull, Cori Blauer-Peterson, Ami R Buikema, Riju Ray, Richard H Stanford
BACKGROUND: Improved outcomes have been reported for patients with chronic obstructive pulmonary disease (COPD) receiving combination long-acting muscarinic antagonist/long-acting β2 -agonist (LAMA/LABA) therapy compared with LAMA monotherapy. However, little is known about the relative characteristics of these patients and their rates of escalation to triple therapy (TT, combining a LAMA, LABA, and inhaled corticosteroid). This study aimed to characterize patients initiating treatment with the LAMA tiotropium (TIO) and the fixed-dose LAMA/LABA combination therapy umeclidinium/vilanterol (UMEC/VI), and to compare rates of escalation to TT between patients receiving these therapies...
June 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29851732/the-impact-of-worksite-clinics-on-teacher-healthcare-utilization-and-cost-self-reported-health-status-and-student-academic-achievement-growth-in-a-public-school-district
#15
John B Engberg, Jon Harris-Shapiro, David Hines, Patti McCarver, Harry H Liu
OBJECTIVE: To examine the impact of worksite clinics on healthcare utilization and cost, self-reported health status, and student achievement growth in a public school district. METHODS: We used insurance claims, health risk assessment, and student achievement growth data for active teachers during 2007-2015. A difference-in-differences approach was applied to measure the impact of worksite clinics. RESULTS: Compared to using a community-based clinic as the usual source of primary care, using a worksite clinic was associated with significantly lower inpatient admissions (53 vs...
May 29, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29843664/predictors-of-latent-tuberculosis-infection-treatment-completion-in-the-us-private-sector-an-analysis-of-administrative-claims-data
#16
Erica L Stockbridge, Thaddeus L Miller, Erin K Carlson, Christine Ho
BACKGROUND: Factors that affect latent tuberculosis infection (LTBI) treatment completion in the US have not been well studied beyond public health settings. This gap was highlighted by recent health insurance-related regulatory changes that are likely to increase LTBI treatment by private sector healthcare providers. We analyzed LTBI treatment completion in the private healthcare setting to facilitate planning around this important opportunity for tuberculosis (TB) control in the US...
May 29, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29808287/risk-reducing-mastectomy-rates-in-the-us-a-closer-examination-of-the-angelina-jolie-effect
#17
Alexander Liede, Mona Cai, Tamara Fidler Crouter, Daniela Niepel, Fiona Callaghan, D Gareth Evans
PURPOSE: In 2013, Angelina Jolie disclosed in the New York Times (NYT) that she had undergone risk-reducing bilateral mastectomy (RRBM) after learning that she was a BRCA1 mutation carrier. We examined the rates of BRCA testing and RRBM from 1997 to 2016, and quantified trends before and after the Jolie op-ed. METHODS: This observational study of insurance claims data representative of the commercially-insured US population (Truven MarketScan® database) measured BRCA testing and RRBM rates among females ≥ 18 years...
May 28, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29802705/colorectal-cancer-screening-among-korean-americans-in-chicago-does-it-matter-whether-they-had-the-screening-in-korea-or-the-us
#18
Shin Young Lee
Background: Colorectal cancer (CRC) is one of the most common cancers in Korean Americans (KAs) and CRC screening can detect CRC early and may reduce the incidence of CRC by leading to removal of precancerous polyps. Many KAs in the US leave the country, primarily to travel to Korea, for health screening. The aim of this study was to (a) assess CRC screening rates, including fecal occult blood test (FOBT), flexible sigmoidoscopy, and colonoscopy and (b) explore factors related to these tests among KAs by location of CRC screening...
May 26, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29800213/trends-in-prescription-medication-use-among-children-and-adolescents-united-states-1999-2014
#19
Craig M Hales, Brian K Kit, Qiuping Gu, Cynthia L Ogden
Importance: Access to appropriate prescription medications, use of inappropriate or ineffective treatments, and adverse drug events are public health concerns among US children and adolescents. Objective: To evaluate trends in use of prescription medications among US children and adolescents. Design, Setting, and Participants: US children and adolescents aged 0 to 19 years in the 1999-2014 National Health and Nutrition Examination Survey (NHANES)-serial cross-sectional, nationally representative surveys of the civilian noninstitutionalized population...
May 15, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29800182/association-of-surgical-left-atrial-appendage-occlusion-with-subsequent-stroke-and-mortality-among-patients-undergoing-cardiac-surgery
#20
Xiaoxi Yao, Bernard J Gersh, David R Holmes, Rowlens M Melduni, Daniel O Johnsrud, Lindsey R Sangaralingham, Nilay D Shah, Peter A Noseworthy
Importance: Surgical occlusion of the left atrial appendage (LAAO) may be performed during concurrent cardiac surgery. However, few data exist on the association of LAAO with long-term risk of stroke, and some evidence suggests that this procedure may be associated with subsequent development of atrial fibrillation (AF). Objective: To evaluate the association of surgical LAAO performed during cardiac surgery with risk of stroke, mortality, and development of subsequent AF...
May 22, 2018: JAMA: the Journal of the American Medical Association
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