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https://www.readbyqxmd.com/read/28746389/a-model-for-simulating-the-active-dispersal-of-juvenile-sea-turtles-with-a-case-study-on-western-pacific-leatherback-turtles
#1
Philippe Gaspar, Maxime Lalire
Oceanic currents are known to broadly shape the dispersal of juvenile sea turtles during their pelagic stage. Accordingly, simple passive drift models are widely used to investigate the distribution at sea of various juvenile sea turtle populations. However, evidence is growing that juveniles do not drift purely passively but also display some swimming activity likely directed towards favorable habitats. We therefore present here a novel Sea Turtle Active Movement Model (STAMM) in which juvenile sea turtles actively disperse under the combined effects of oceanic currents and habitat-driven movements...
2017: PloS One
https://www.readbyqxmd.com/read/28741841/pulmonary-valve-opening-with-two-rotary-left-ventricular-assist-devices-for-biventricular-support
#2
Eric L Wu, Frank Nestler, Matthias Kleinheyer, Michael C Stevens, Jo P Pauls, John F Fraser, Shaun D Gregory
Right ventricular failure is a common complication associated with rotary left ventricular assist device (LVAD) support. Currently, there is no clinically approved long-term rotary right ventricular assist device (RVAD). Instead, clinicians have implanted a second rotary LVAD as RVAD in biventricular support. To prevent pulmonary hypertension, the RVAD must be operated by either reducing pump speed or banding the outflow graft. These modes differ in hydraulic performance, which may affect the pulmonary valve opening (PVO) and subsequently cause fusion, valvular insufficiency, and thrombus formation...
July 25, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28741348/super-resolution-far-field-infrared-imaging-by-photothermal-heterodyne-imaging
#3
Zhongming Li, Kyle Aleshire, Masaru Kuno, Gregory V Hartland
Infrared (IR) imaging provides chemical-specific information without the need for exogenous labels. Conventional far-field IR imaging techniques are diffraction limited, which means an effective spatial resolution of > 5 μm with currently available optics. In this paper we present a novel far-field IR imaging technique based on photothermal heterodyne imaging (IR-PHI). In our version of IR-PHI an IR pump laser excites the sample, causing a small temperature rise that is detected by a counter-propagating visible probe beam...
July 25, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28738554/amperometric-detector-for-gas-chromatography-based-on-a-silica-sol-gel-solid-electrolyte
#4
William H Steinecker, Krzysztof Miecznikowski, Pawel J Kulesza, Zechariah D Sandlin, James A Cox
An electrochemical cell comprising a silica sol-gel solid electrolyte, a working electrode that protrudes into a gas phase, and reference and counter electrodes that contact the solid electrolyte comprises an amperometric detector for gas chromatography. Under potentiostatic conditions, a current related to the concentration of an analyte in the gas phase is produced by its oxidation at the three-phase boundary among the sol-gel, working electrode, and the gas phase. The sol-gel is processed to contain an electrolyte that also serves as a humidistat to maintain a constant water activity even in the presence the gas chromatographic mobile phase...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28737242/customers-perceptions-of-and-satisfaction-with-medicine-retail-outlet-services-in-addis-ababa-ethiopia-a-cross-sectional-study
#5
Dawit T Gebregeorgise, Tofik A Mohammed, Zebiba S Redi, Sofia Kälvemark Sporrong
OBJECTIVES: The aim of this study was to assess customers' perceptions of and satisfaction with MRO services in Addis Ababa and to explore factors associated with their satisfaction and reasons for visits. METHODS: A cross-sectional survey was conducted among customers selected from 28 MROs in Addis Ababa, using multi-stage sampling techniques. Simple descriptive statistics and multivariable logistic regression at 95% confidence interval were used for the analysis...
July 24, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28737178/electrokinetics-and-behavior-near-the-interface-of-colloidal-particles-in-non-polar-dispersions
#6
Manoj Prasad, Filip Strubbe, Filip Beunis, Kristiaan Neyts
The electrokinetics and charging of nonpolar colloidal dispersions subjected to a voltage are investigated by electric current and optical measurements. From electric current measurements in response to an alternating triangular voltage with a peak value of a few hundred volts, we find that polystyrene toner particles are compacted near the electrodes and their charge increases by more than a factor of 20. The important increase of charge is interpreted by a mechanism in which counter charges, which are originally at the particle surface, are desorbed...
July 24, 2017: Soft Matter
https://www.readbyqxmd.com/read/28734939/public-health-acetaminophen-apap-hepatotoxicity-isn-t-it-time-for-apap-to-go-away
#7
REVIEW
William M Lee
Acetaminophen (APAP) is the most commonly used drug for the treatment of pain and fever around the world. At the same time, APAP is capable of causing dose-related hepatocellular necrosis, responsible for nearly 500 deaths annually in the U.S. alone, as well as 100,000 calls to US Poison Control Centers, 50,000 emergency room visits and 10,000 hospitalizations per year. As an over-the-counter and prescription product (with opioids), APAP toxicity dwarfs all other prescription drugs as a cause for acute liver failure in the United States and Europe, but is not regulated in any significant way...
July 19, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28733944/the-gastric-and-intestinal-microbiome-role-of-proton-pump-inhibitors
#8
REVIEW
Artem Minalyan, Lilit Gabrielyan, David Scott, Jonathan Jacobs, Joseph R Pisegna
PURPOSE OF REVIEW: The discovery of Helicobacter pylori and other organisms colonizing the stomach and the intestines has shed some light on the importance of microbiome in maintaining overall health and developing pathological conditions when alterations in biodiversity are present. The gastric acidity plays a crucial role in filtering out bacteria and preventing development of enteric infections. In this article, we discuss the physiology of gastric acid secretion and bacterial contribution to the composition of gastric and intestinal barriers and review the current literature on the role of proton pump inhibitors (PPIs) in the microbial biodiversity of the gastrointestinal tract...
August 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28732888/separation-of-polysaccharides-from-spirulina-platensis-by-hsccc-with-ethanol-ammonium-sulfate-atps-and-their-antioxidant-activities
#9
Xueyan Wu, Ruichang Li, Yongjie Zhao, Yang Liu
Three separation methods for water-soluble polysaccharides from Spirulina platensis (PSP) were compared, including sevage deproteinization and column chromatography, ethanol-ammonium sulfate aqueous two-phase system (ATPS) and column chromatography, and one-step high speed counter-current chromatography (HSCCC) with ethanol-ammonium sulfate ATPS. ATPS was confirmed as an efficient alternative method of protein removal for PSP purification. For the HSCCC with ethanol-ammonium sulfate ATPS, the stationary retention reached to 50...
October 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28731312/gentiana-kurroo-royle-attenuates-the-metabolic-aberrations-in-diabetic-rats-swertiamarin-swertisin-and-lupeol-being-the-possible-bioactive-principles
#10
Khalid Ghazanfar, Khan Mubashir, Showkat A Dar, Tazeen Nazir, Iqra Hameed, Bashir A Ganai, Seema Akbar, Akbar Masood
Background Gentiana kuroo Royle is a medicinally important plant of north-western Himalayas used for various ailments. In the present study, the plant extracts were investigated for the antidiabetic effects in streptozotocin-induced diabetic rats. Methods The impact of the extracts on serum glucose levels of diabetic rats was compared with reference drug - glibenclamide-treated diabetic rats. Streptozotocin injection was used to induce diabetes in fasted rats. Various biochemical, physiological and histopathological parameters in diabetic rats were observed for assessing the antidiabetic activity...
April 29, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28726768/characterization-and-purification-of-bergamottin-from-citrus-grandis-l-osbeck-cv-yongjiazaoxiangyou-and-its-antiproliferative-activity-and-effect-on-glucose-consumption-in-hepg2-cells
#11
Yilong Liu, Chuanhong Ren, Yunlin Cao, Yue Wang, Wenyi Duan, Linfeng Xie, Chongde Sun, Xian Li
Bergamottin is a natural furanocoumarin compound with weak polarity. Characterization and quantification of bergamottin were carried out in different fruit tissues of various citrus cultivars. Among the four citrus tissues tested, i.e., flavedo, albedo, segment membrane (SM), and juice sacs (JS) in eight citrus cultivars, the highest bergamottin content was found in the flavedo of Citrus grandis (L.) Osbeck cv. Yongjiazaoxiangyou (YJZXY, 666.54 μg·g(-1) DW). A combination of silica gel column chromatography and high-speed counter-current chromatography (HSCCC) was established to efficiently purify bergamottin from the flavedo of YJZXY...
July 20, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28726727/in-vitro-quantified-determination-of-%C3%AE-amyloid-42-peptides-a-biomarker-of-neuro-degenerative-disorders-in-pbs-and-human-serum-using-a-simple-cost-effective-thin-gold-film-biosensor
#12
Yifan Dai, Alireza Molazemhosseini, Chung Chiun Liu
A simple in vitro biosensor for the detection of β-amyloid 42 in phosphate-buffered saline (PBS) and undiluted human serum was fabricated and tested based on our platform sensor technology. The bio-recognition mechanism of this biosensor was based on the effect of the interaction between antibody and antigen of β-amyloid 42 to the redox couple probe of K₄Fe(CN)₆ and K₃Fe(CN)₆. Differential pulse voltammetry (DPV) served as the transduction mechanism measuring the current output derived from the redox coupling reaction...
July 20, 2017: Biosensors
https://www.readbyqxmd.com/read/28724460/health-and-well-being-promotion-strategies-for-hard-to-reach-older-people-in-england-a-mapping-exercise
#13
Steve Iliffe, Kate Walters, Jill Manthorpe, Claire Goodman, Kalpa Kharicha
BACKGROUND: Older people from deprived areas, the oldest old and those from ethnic minorities engage less in health promotion interventions and related research, potentially generating inequities. Aim To explore and map the extent to which such 'hard to reach' groups of older people, are the focus of local health and well-being strategies in England. METHODS: Document analysis of current health and well-being promotion strategies in a purposive sample of 10 localities in England with high proportions of some or all of the three hard to reach groups...
July 20, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28721311/from-kaua-i-to-hawai-i-island-interisland-differences-in-emergency-contraceptive-pill-availability
#14
Holly Bullock, Mary Tschann, Jennifer Elia, Bliss Kaneshiro, Jennifer Salcedo
Emergency contraceptive pills (ECPs) are medications used after unprotected intercourse, underprotected intercourse, or sexual assault to decrease the risk of pregnancy. Availability of ECPs in Hawai'i's retail pharmacies was last assessed in 2007, following over-the-counter access to levonorgestrel ECPs (LNG-ECP) for women age 18 years or older and prior to U.S. Food and Drug Administration (FDA) approval of prescription-only ulipristal acetate (UPA). We conducted a county-by-county subanalysis from a larger observational population-based study on statewide availability of ECPs in Hawai'i's pharmacies...
July 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28715674/the-presence-of-licit-and-illicit-drugs-in-police-stations-and-their-implications-for-workplace-drug-testing
#15
Gregory S Doran, Ralph Deans, Carlo De Filippis, Chris Kostakis, Julia A Howitt
The presence of licit and illicit drug residues on surfaces was studied in 10 police stations and a central drug evidence store in New South Wales, Australia, with the results compared to similar surfaces in four public buildings (to establish a community baseline). The results of almost 850 workplace surface swabs were also compared to the outcome of drug analysis in urine and hair samples volunteered by police officers. Surfaces were swabbed with alcohol and the swabs were extracted and analysed by LC-MS/MS...
July 5, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28713256/baseline-performance-predicts-tdcs-mediated-improvements-in-language-symptoms-in-primary-progressive-aphasia
#16
Eric M McConathey, Nicole C White, Felix Gervits, Sherry Ash, H Branch Coslett, Murray Grossman, Roy H Hamilton
Primary Progressive Aphasia (PPA) is a neurodegenerative condition characterized by insidious irreversible loss of language abilities. Prior studies suggest that transcranial direct current stimulation (tDCS) directed toward language areas of the brain may help to ameliorate symptoms of PPA. In the present sham-controlled study, we examined whether tDCS could be used to enhance language abilities (e.g., picture naming) in individuals with PPA variants primarily characterized by difficulties with speech production (non-fluent and logopenic)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28707978/immunomodulatory-cell-therapy-to-target-cystic-fibrosis-inflammation
#17
Oula Khoury, Christopher Barrios, Victor Ortega, Anthony Atala, Sean V Murphy
Cystic fibrosis (CF) is associated with exaggerated and prolonged inflammation in the lungs, which contributes to lung injury, airway mucus obstruction, bronchiectasis and loss of lung function. This hyper-inflammatory phenotype appears to be caused by an imbalance between the pro- and anti-inflammatory regulatory pathways, with heightened pro-inflammatory stimuli, a decreased counter-regulatory response, and reduced effectiveness of immune cell function and inflammatory resolution. Thus, therapies that can target this inflammatory environment would have a major impact in preventing the progression of lung disease...
July 14, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28705991/oxygen-metabolism-and-innate-immune-responses-in-the-gut
#18
Sean Patrick Colgan, Eric L Campbell
Epithelial cells of the mucosa provide a first line of protection against the inappropriate flux of antigens from the outside world. In the gastrointestinal (GI) tract, this barrier is provided at a number of levels, including mucus production, epithelial junctional complexes and the production of antimicrobial molecules. In recent years, it is better appreciated that tissue oxygen metabolism is key to homeostasis in the mucosa. The intestine, for example, maintains a low baseline pO2 levels due to counter-current blood flow and the presence of large numbers of bacteria...
July 13, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28700214/capacitive-neutralisation-dialysis-for-direct-energy-generation
#19
Yue Liu, Yi Zhang, Wei Ou-Yang, Bruno Bastos Sales, Zhuo Sun, Fei Liu, Ran Zhao
Capacitive neutralisation dialysis energy (CNDE) is proposed as a novel energy-harvesting technique that is able to utilise waste acid and alkaline solutions to produce electrical energy. CNDE is a modification based on neutralisation dialysis. It was found that a higher NaCl concentration led to a higher open circuit potential when the concentrations of acid and alkaline solutions were fixed. Upon closing the circuit, the membrane potential was used as a driving force to move counter ions into the electrical double layers at the electrode-liquid interface, thereby creating an ionic current...
July 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28698171/natural-compounds-for-the-treatment-of-psoriatic-arthritis-a-proposal-based-on-multi-targeted-osteoclastic-regulation-and-on-a-preclinical-study
#20
Shiqiang Deng, Jianwen Cheng, Jinmin Zhao, Felix Yao, Jiake Xu
BACKGROUND: Psoriatic arthritis (PsA) is a chronic inflammatory arthritis affecting approximately 2% to 3% of the population globally, and is characterized by both peripheral articular manifestations and axial skeletal involvement. Conventional therapies for PsA have not been fully satisfactory, though natural products (NPs) have been shown to be highly effective and represent important treatment options for psoriasis. PsA is a multigenic autoimmune disease with both environmental and genetic factors contributing to its pathogenesis...
July 11, 2017: JMIR Research Protocols
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