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https://www.readbyqxmd.com/read/29756162/retrospective-analysis-of-mepivacaine-prilocaine-and-chloroprocaine-for-low-dose-spinal-anaesthesia-in-outpatient-perianal-procedures
#1
Volker Gebhardt, Kevin Kiefer, Dieter Bussen, Christel Weiss, Marc D Schmittner
PURPOSE: Perianal procedures are carried out in an outpatient setting regularly. The purpose of this retrospective analysis was to investigate the impact of different local anaesthetics (LA) for spinal anaesthesia (SPA) on operating room (OR) efficiency (perioperative process times, turnaround times) and postoperative recovery. This study aims on the determination of the optimal LA for low-dose SPA in the specific setting of a high-volume day-surgery centre. METHODS: Anaesthesia records of all patients undergoing perianal outpatient surgery under saddle-block SPA at the Mannheim University Medical Centre from 2008 until 2017 were analysed...
May 13, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29744621/carotid-artery-intima-media-thickness-measurement-in-children-with-normal-and-increased-body-mass-index-a-comparison-of-three-techniques
#2
Ramy El Jalbout, Guy Cloutier, Marie-Hélène Roy Cardinal, Mélanie Henderson, Chantale Lapierre, Gilles Soulez, Josée Dubois
BACKGROUND: Common carotid artery intima-media thickness is a marker of subclinical atherosclerosis. In children, increased intima-media thickness is associated with obesity and the risk of cardiovascular events in adulthood. OBJECTIVE: To compare intima-media thickness measurements using B-mode ultrasound, radiofrequency (RF) echo tracking, and RF speckle probability distribution in children with normal and increased body mass index (BMI). MATERIALS AND METHODS: We prospectively measured intima-media thickness in 120 children randomly selected from two groups of a longitudinal cohort: normal BMI and increased BMI, defined by BMI ≥85th percentile for age and gender...
May 9, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29739796/prevalence-of-carotid-plaque-in-a-63-to-65-year-old-norwegian-cohort-from-the-general-population-the-ace-akershus-cardiac-examination-1950-study
#3
Håkon Ihle-Hansen, Thea Vigen, Hege Ihle-Hansen, Ole Morten Rønning, Trygve Berge, Bente Thommessen, Magnus Nakrem Lyngbakken, Eivind Bjørkan Orstad, Steve Enger, Ståle Nygård, Helge Røsjø, Arnljot Tveit
BACKGROUND: New data on extracranial carotid atherosclerosis are needed, as improved ultrasound techniques may detect more atherosclerosis, the definition of plaque has changed over the years, and better cardiovascular risk control in the population may have changed patterns of carotid arterial wall disease and actual prevalence of established cardiovascular disease. We investigated the prevalence of atherosclerotic carotid plaques and carotid intima-media thickness (cIMT) and their relation to cardiovascular risk factors in a middle-aged cohort from the general population...
May 8, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29730273/differences-in-associations-of-antiepileptic-drugs-and-hospitalization-due-to-hyponatremia-a-population-based-case-control-study
#4
Henrik Falhammar, Jonatan D Lindh, Jan Calissendorff, Shermineh Farmand, Jakob Skov, David Nathanson, Buster Mannheimer
PURPOSE: Hyponatremia induced by antiepileptic drugs is common, but detailed evidence is lacking. This can be problematic for the treating neurologist confronted with a patient with severe hyponatremia in need of an alternative drug. The objective of this study was to examine the association between individual antiepileptic drugs and hospitalization due to hyponatremia. METHODS: This was a register-based case-control study of patients in the general Swedish population...
April 30, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29697196/abstractband-anl%C3%A3-%C3%A3-lich-der-26-jahrestagung-der-arbeitsgemeinschaft-dermatologische-histologie-adh-11-13-mai-2018-in-mannheim-germany
#5
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29659470/meta-analysis-of-perioperative-outcomes-of-acute-laparoscopic-vs-open-repair-of-perforated-gastroduodenal-ulcers
#6
Roberto Cirocchi, Kjetil Soreide, Salomone Di Saverio, Elena Rossi, Alberto Arezzo, Mauro Zago, Iosief Abraha, Nereo Vettoretto, Massimo Chiarugi
BACKGROUND: Surgery is the treatment of choice for perforated peptic ulcer disease (PUD). The aim of the present review is to compare the perioperative outcomes of acute laparoscopic versus open repair for PUD. METHODS: A systematic literature search was performed for randomized controlled trials (RCTs) published in PubMed, SCOPUS and Web of Science RESULTS: The search included eight RCTs: 615 patients comparing laparoscopic (307 patients) versus open peptic perforated ulcer repair (308 patients)...
April 13, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29651553/fistulectomy-with-primary-sphincter-reconstruction
#7
Steffen Seyfried, Dieter Bussen, Andreas Joos, Christian Galata, Christel Weiss, Alexander Herold
AIM: Despite modern medical techniques, anatomically proximal (high) anal fistulas are still a challenge in colorectal surgery. In previous years, the standard of care was complete fistulectomy with a high rate of continence disorders. Over the past 20 to 30 years, sphincter-saving procedures have gained wide acceptance. They represent the technique used in these cases. Additionally, many patients received indefinite treatment, namely the placement of a seton to maintain surgical drainage...
April 12, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29619788/effects-of-high-frequency-high-intensity-transcutaneous-electrical-nerve-stimulation-versus-intravenous-opioids-for-pain-relief-after-gynecologic-laparoscopic-surgery-a-randomized-controlled-study
#8
Birgitta Platon, Clas Mannheimer, Paulin Andréll
BACKGROUND: The aim of the study was to compare the pain relieving effect and the time spent in the recovery unit after treatment with high frequency, high-intensity transcutaneous electrical nerve stimulation (TENS) or intravenous (IV) opioids after gynecologic laparoscopic surgery. METHODS: All patients who postoperatively reported visual analogue scale (VAS) pain score ≥ 3 were consecutively included in the study. The TENS treatment was given with a stimulus intensity between 40-60 mA during 1 minute, repeated once if insufficient pain relief...
April 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29610606/thyroid-function-and-25-oh-vitamin-d-level-among-sudanese-women-in-early-pregnancy
#9
Imad R Musa, Duria A Rayis, Mohmamed A Ahmed, Ammar H Khamis, Abubakr M Nasr, Ishag Adam
AIM: A cross-sectional study was conducted at Saad Abualila Hospital (Khartoum, Sudan) to evaluate the vitamin D levels and thyroid function among pregnant Sudanese women (132) in early pregnancy. METHODS: A cross-sectional study was conducted at Saad Abualila hospital (Khartoum, Sudan) during the period from March to July 2015. Women who were in early pregnancy with a singleton pregnancy were approached to participate in the study after signing informed consent...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29589103/-84th-annual-meeting-of-the-german-cardiac-society-cardiac-and-circulation-research-april-4-7-2018-mannheim
#10
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29567294/a-meta-analysis-and-systematic-literature-review-of-factors-associated-with-sexual-risk-taking-during-international-travel
#11
REVIEW
Pia Svensson, Mats Sundbeck, Kristina Ingemarsdotter Persson, Martin Stafström, Per-Olof Östergren, Louise Mannheimer, Anette Agardh
BACKGROUND: International travel facilitates global spread of sexually transmitted infections (STI). Travellers could contribute to onward transmission of pathogens rarely encountered at home and export new strains to the destination. The aim was to systematically examine evidence regarding determinants of travel-related sexual risk-taking and identify knowledge gaps and areas for targeted interventions. METHOD: Articles published in peer-reviewed journals from 2000 to 2017 were screened in 6 databases and assessed for relevance against criteria...
March 19, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29566005/evaluation-of-the-cobas%C3%A2-gt-hepatitis-c-virus-genotyping-assay-in-g1-6-viruses-including-low-viral-loads-and-lipa-failures
#12
Benjamin Némoz, Léa Roger, Vincent Leroy, Jean-Dominique Poveda, Patrice Morand, Sylvie Larrat
Direct-acting antiviral (DAA) drug performances depend on the viral genotype. So international recommendations give typing of the virus a prerequisite for treatment choice and patient management. Commercially available HCV genotyping kits are scarce and this analysis is often in-house using tedious PCRs and Sanger sequencing, leading to a lack of standardization. A newly commercialized HCV genotyping assay based on real-time PCR has been developed by Roche Diagnostics (Mannheim, Germany). We compared this new assay with our in-house PCRs -sequencing technique on 101 regular samples and 81 LiPA failures or low viral load samples...
2018: PloS One
https://www.readbyqxmd.com/read/29537178/multiple-strategies-to-identify-hiv-positive-black-men-who-have-sex-with-men-and-transgender-women-in-new-york-city-a-cross-sectional-analysis-of-recruitment-results
#13
Julie Franks, Sharon B Mannheimer, Yael Hirsch-Moverman, Eleanor Hayes-Larson, Paul W Colson, Hugo Ortega, Wafaa M El-Sadr
INTRODUCTION: Black men who have sex with men and transgender women are at high risk for HIV infection, but are more likely to be unaware of their infection or not in care for diagnosed HIV compared to other races. Respondent driven sampling has been advanced as a method to reach stigmatized and hidden populations for HIV testing. We compared strategies to recruit black, substance-using men who have sex with men and transgender women to identify newly diagnosed HIV infection, or those previously diagnosed but not in care...
March 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29536238/damage-control-surgery-in-perforated-diverticulitis-ongoing-peritonitis-at-second-surgery-predicts-a-worse-outcome
#14
M A Sohn, A Agha, P Steiner, A Hochrein, M Komm, R Ruppert, P Ritschl, F Aigner, I Iesalnieks
PURPOSE: Damage control strategy (DCS) is a two-staged procedure for the treatment of perforated diverticular disease complicated by generalized peritonitis. The aim of this retrospective multicenter cohort study was to evaluate the prognostic impact of an ongoing peritonitis at the time of second surgery. METHODS: Consecutive patients who underwent DCS for perforated diverticular disease of the sigmoid colon with generalized peritonitis at four surgical centers were included...
March 13, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29534652/the-impact-of-absolute-cd4-count-and-percentage-discordance-on-pneumocystis-jirovecii-pneumonia-prophylaxis-in-hiv-infected-patients
#15
Henry Anyimadu, Chandra Pingili, Vel Sivapalan, Yael Hirsch-Moverman, Sharon Mannheimer
Current guidelines suggest that HIV-infected patients should receive chemoprophylaxis against Pneumocystis jirovecii pneumonia (PJP) if they have a cluster determinant 4 (CD4) count <200 cells/mm3 or oropharyngeal candidiasis. Persons with CD4 percentage (CD4%) below 14% should also be considered for prophylaxis. Discordance between CD4 count and CD4% occurs in 16% to 25% of HIV-infected patients. Provider compliance with current PJP prophylaxis guidelines when such discordance is present was assessed. Electronic medical records of 429 HIV-infected individuals who had CD4 count and CD4% measured at our clinic were reviewed...
January 2018: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/29525349/high-cdkn2a-p16-and-low-fgfr3-expression-predict-progressive-potential-of-stage-pt1-urothelial-bladder-carcinoma
#16
Johannes Breyer, Ralph M Wirtz, Philipp Erben, Thomas S Worst, Robert Stoehr, Markus Eckstein, Simone Bertz, Danijel Sikic, Stefan Denzinger, Maximilian Burger, Arndt Hartmann, Wolfgang Otto
BACKGROUND: A recent study on the comprehensive genomic profile of advanced urothelial bladder cancer (UBC) showed cyclin-dependent kinase inhibitor 2A (CDKN2A) and fibroblast growth factor receptor 3 (FGFR3) as the most often clinically relevant genomic alterations. Therefore, the prognostic role of FGFR3 and CDKN2A/p16 for pT1 UBC was studied. PATIENTS AND METHODS: Clinical data and formalin-fixed paraffin-embedded tissues of pT1 UBC treated with an organ-preserving approach was analyzed retrospectively...
February 2, 2018: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29521661/spinal-anaesthesia-with-chloroprocaine-1-versus-total-intravenous-anaesthesia-for-outpatient-knee-arthroscopy-a-randomised-controlled-trial
#17
Volker Gebhardt, Vera Zawierucha, Oliver Schöffski, Anke Schwarz, Christel Weiss, Marc D Schmittner
BACKGROUND: Both general and spinal anaesthesia with short-acting local anaesthetics are suitable and reliable for knee arthroscopy as an ambulatory procedure. Chloroprocaine (CP) 1% seems to be the ideal spinal local anaesthetic for this indication. OBJECTIVE: The aim of this study was to compare spinal anaesthesia using CP 1% with general for outpatient knee arthroscopy with regard to procedure times, occurrence of pain, patient satisfaction and recovery, and also costs...
March 7, 2018: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29498033/media-exposure-to-terrorism-and-people-s-risk-perception-the-role-of-environmental-sensitivity-and-psychophysiological-response-to-stress
#18
Enrico Rubaltelli, Sara Scrimin, Ughetta Moscardino, Giulia Priolo, Giulia Buodo
Terrorist attacks have a destabilizing impact on the general population, causing distress and fear. However, not all individuals are equally susceptible to the effects of terror threat. This study aimed to examine whether exposure to terrorism-related pictures interacted with individual differences in environmental sensitivity and psychophysiological response to stress to explain people's risk perception, operationalized as perceived likelihood of a terrorist attack and willingness to trade off one's privacy to increase national security...
March 2, 2018: British Journal of Psychology
https://www.readbyqxmd.com/read/29497691/competency-based-learning-in-an-ambulatory-care-setting-implementation-of-simulation-training-in-the-ambulatory-care-rotation-during-the-final-year-of-the-marecum-model-curriculum
#19
Martin Dusch, Elisabeth Narciß, Renate Strohmer, Katrin Schüttpelz-Brauns
Aim: As part of the MaReCuM model curriculum at Medical Faculty Mannheim Heidelberg University, a final year rotation in ambulatory care was implemented and augmented to include ambulatory care simulation. In this paper we describe this ambulatory care simulation, the designated competency-based learning objectives, and evaluate the educational effect of the ambulatory care simulation training. Method: Seventy-five final year medical students participated in the survey (response rate: 83%). The control group completed the ambulatory rotation prior to the implementation of the ambulatory care simulation...
2018: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29489462/monitoring-of-antiplatelet-therapy-in-children-on-ventricular-assist-device-support-comparison-of-multiplate-and-thromboelastography-platelet-mapping
#20
Lee P Ferguson, Phuoc Duong, Kim F Pearce, Paul Murphy, Tina T Biss
The optimal method for monitoring antiplatelet therapy in children supported with ventricular assist devices (VADs) is unknown. We conducted a retrospective study to compare Thromboelastography Platelet Mapping (TEG/PM) with multiple electrode platelet aggregometry (MEA) on a Multiplate analyzer (Roche Diagnostics, Mannheim, Germany). We analyzed data from 66 paired blood samples from 9 patients <16 years of age on VAD where platelet function was simultaneously measured with TEG/PM and MEA. Antiplatelet dose-response relationships and intraindividual variability during steady state therapy were determined...
February 27, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
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