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https://www.readbyqxmd.com/read/29143163/sex-prep-and-stigma-experiences-with-hiv-pre-exposure-prophylaxis-among-new-york-city-msm-participating-in-the-hptn-067-adapt-study
#1
Julie Franks, Yael Hirsch-Moverman, Avelino S Loquere, K Rivet Amico, Robert M Grant, Bonnie J Dye, Yan Rivera, Robert Gamboa, Sharon B Mannheimer
The HPTN 067/Alternative Dosing to Augment Pre-Exposure Prophylaxis Pill Taking (ADAPT) study evaluated daily and non-daily dosing schedules for oral pre-exposure prophylaxis (PrEP) to prevent HIV. A qualitative sub-study including focus groups and in-depth interviews was conducted among men who have sex with men participating in New York City to understand their experience with PrEP and study dosing schedules. The 37 sub-study participants were 68% black, 11% white, and 8% Asian; 27% were of Hispanic/Latino ethnicity...
November 15, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29110680/fraction-of-high-grade-cervical-intraepithelial-lesions-attributable-to-genotypes-targeted-by-a-nonavalent-hpv-vaccine-in-galicia-spain
#2
S Perez, A Iñarrea, R Pérez-Tanoira, M Gil, E López-Díez, O Valenzuela, M Porto, L Alberte-Lista, M A Peteiro-Cancelo, A Treinta, R Carballo, M C Reboredo, M E Alvarez-Argüelles, M J Purriños
BACKGROUND: Human papillomavirus (HPV) bivalent and quadrivalent vaccines have been widely implemented in worldwide organized immunization programs. A nonavalent HPV vaccine is now available in several countries. The objective was to describe the fraction of squamous non-invasive high-grade cervical intraepithelial lesions attributable to genotypes targeted by bi-quadrivalent vaccines and by nonavalent vaccine according to age and diagnosis in women living in the city of Vigo (Galicia, Spain)...
November 6, 2017: Virology Journal
https://www.readbyqxmd.com/read/28971332/standardization-of-small-animal-imaging-current-status-and-future-prospects
#3
REVIEW
Julia G Mannheim, Firat Kara, Janine Doorduin, Kerstin Fuchs, Gerald Reischl, Sayuan Liang, Marleen Verhoye, Felix Gremse, Laura Mezzanotte, Marc C Huisman
The benefit of small animal imaging is directly linked to the validity and reliability of the collected data. If the data (regardless of the modality used) are not reproducible and/or reliable, then the outcome of the data is rather questionable. Therefore, standardization of the use of small animal imaging equipment, as well as of animal handling in general, is of paramount importance. In a recent paper, guidance for efficient small animal imaging quality control was offered and discussed, among others, the use of phantoms in setting up a quality control program (Osborne et al...
October 2, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28957814/prevalence-and-incidence-of-autoimmune-pancreatitis-in-the-population-living-in-the-southwest-of-germany
#4
Alexander Schneider, Henrik Michaely, Christel Weiss, Michael Hirth, Felix Rückert, Torsten J Wilhelm, Stefan Schönberg, Alexander Marx, Manfred V Singer, J Matthias Löhr, Matthias P Ebert, Roland H Pfützer
BACKGROUND/AIMS: The prevalence and incidence of autoimmune pancreatitis (AiP) in those living in western countries are largely unknown. We aimed to determine the prevalence of AiP among patients with pancreatitis presenting to our tertiary referral center in Mannheim, Germany; and to estimate the incidence of AiP in the Southwest of Germany. METHODS: We performed a retrospective cross-sectional analysis and determined the prevalence of AiP in patients with acute pancreatitis (AP) or chronic pancreatitis (CP)...
September 29, 2017: Digestion
https://www.readbyqxmd.com/read/28947401/non-traumatic-acute-peritonitis-in-children-causes-and-prognosis-in-226%C3%A2-patients-at-the-national-hospital-of-zinder-niger
#5
H Adamou, O Habou, I Amadou-Magagi, M Doutchi, M Amadou, M Halidou
To report etiological and prognostic characteristics of acute peritonitis in children. This retrospective study reviewed the records for a 30-month period (January 2013-June 2015) at Zinder National Hospital (Niger) of all children between the ages of 0-15 years who underwent surgery for non-traumatic acute peritonitis. Statistical tests were performed, with significance defined by a P-value < 5 %. Acute peritonitis accounted for 62.12 % (226/358) of all emergency gastrointestinal surgery in children...
August 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28943323/hartmann-s-procedure-or-primary-anastomosis-for-generalized-peritonitis-due-to-perforated-diverticulitis-a-prospective-multicenter-randomized-trial-diverti
#6
Valerie Bridoux, Jean Marc Regimbeau, Mehdi Ouaissi, Muriel Mathonnet, Francois Mauvais, Estelle Houivet, Lilian Schwarz, Diane Mege, Igor Sielezneff, Charles Sabbagh, Jean-Jacques Tuech
BACKGROUND: About 25% of patients with acute diverticulitis require emergency intervention. Currently, most patients with diverticular peritonitis undergo a Hartmann's procedure. Our objective was to assess whether primary anastomosis (PA) with a diverting stoma results in lower mortality rates than Hartmann's procedure (HP) in patients with diverticular peritonitis. STUDY DESIGN: We conducted a multicenter randomized controlled trial conducted between June 2008 and May 2012: the DIVERTI (Primary vs Secondary Anastomosis for Hinchey Stage III-IV Diverticulitis) trial...
September 22, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28932873/-interventional-catheter-treatment-of-tricuspid-valve-regurgitation
#7
REVIEW
T Wißt, F Kreidel, M Schlüter, K-H Kuck, C Frerker
BACKGROUND: The tricuspid valve can be considered the "forgotten" valve because in the past hardly any research has been conducted in this field and as a result only few therapeutic options existed. The prognosis of untreated tricuspid regurgitation (TR) is poor and mortality is high for patients with severe TR. Patients frequently return to medical practices and hospitals because of cardiac decompensation, with shortness of breath and leg edema. OBJECTIVE: Recent years have seen more development in catheter-based treatment options...
November 2017: Der Internist
https://www.readbyqxmd.com/read/28821411/diagnosis-and-treatment-in-chronic-pancreatitis-an-international-survey-and-case-vignette-study
#8
Yama Issa, Hjalmar C van Santvoort, Paul Fockens, Marc G Besselink, Thomas L Bollen, Marco J Bruno, Marja A Boermeester
BACKGROUND: The aim of the study was to evaluate the current opinion and clinical decision-making process of international pancreatologists, and to systematically identify key study questions regarding the diagnosis and treatment of chronic pancreatitis (CP) for future research. METHODS: An online survey, including questions regarding the diagnosis and treatment of CP and several controversial clinical case vignettes, was send by e-mail to members of various international pancreatic associations: IHPBA, APA, EPC, ESGE and DPSG...
November 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28803926/differences-in-associations-of-antidepressants-and-hospitalization-due-to-hyponatremia
#9
Shermineh Farmand, Jonatan Lindh, Jan Calissendorff, Jakob Skov, Henrik Falhammar, David Nathanson, Buster Mannheimer
Background Selective serotonin reuptake inhibitors (SSRIs) and other antidepressants are important as a cause for hyponatremia. However, most studies have focused on the effect on sodium levels regardless of clinical symptoms or been too small to be able to discriminate between the effects of specific antidepressant drugs. The objective of the present study was to investigate the association between different groups of antidepressants and the risk of hospitalisation due to hyponatremia. Methods In this register based case-control study of patients in the general Swedish population we identified 14 359 individuals with a main diagnosis of hyponatremia...
August 10, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28791876/limited-awareness-of-pre-exposure-prophylaxis-among-black-men-who-have-sex-with-men-and-transgender-women-in-new%C3%A2-york-city
#10
Matthew Garnett, Yael Hirsch-Moverman, Julie Franks, Eleanor Hayes-Larson, Wafaa M El-Sadr, Sharon Mannheimer
Awareness of Pre-exposure prophylaxis (PrEP) was assessed among a cohort of substance-using black men who have sex with men and transgender women (MSM/TGW) participating in the STAR Study, which recruited black MSM/TGW in New York City for HIV testing and linked HIV-infected individuals into care from July 2012 to April 2015. Sociodemographic, psychosocial, known HIV risk factors, and PrEP awareness were assessed among participants. Multivariable logistic regression was conducted to assess factors associated with PrEP awareness...
August 9, 2017: AIDS Care
https://www.readbyqxmd.com/read/28762450/prognostic-factors-in-acute-mesenteric-ischemia-and-evaluation-with-mannheim-peritonitis-index-and-platelet-to-lymphocyte-ratio
#11
Eyüp Murat Yılmaz, Erdem Barış Cartı
BACKGROUND: Acute mesenteric ischemia (AMI) is a disease that has a very high mortality rate and for which the diagnosis is frequently delayed. The aim of the present study was to assess the predictive value of the Mannheim Peritonitis Index (MPI) and platelet-to-lymphocyte (P/L) ratio in the prognosis of AMI. METHODS: The files of 34 patients diagnosed with AMI between September 2014 and April 2016 were retrospectively examined. The patients were divided into 2 groups based on survival...
July 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28744135/sex-differences-of-in-hospital-outcome-and-long-term-mortality-in-patients-with-takotsubo-cardiomyopathy
#12
K J Weidner, I El-Battrawy, M Behnes, K Schramm, C Fastner, J Kuschyk, U Hoffmann, U Ansari, M Borggrefe, I Akin
BACKGROUND: Previous studies revealed that patients with Takotsubo cardiomyopathy (TTC) have a higher mortality rate than the general population. It is still unclear whether sex differences may influence long-term prognosis of TTC patients. The purpose of this study was to determine whether sex differences do influence the short- and long-term outcomes of TTC. METHODS AND RESULTS: A total of 114 patients with TTC were admitted to the University Medical Centre Mannheim from January 2003 to September 2015 and entered into the TTC database of the University Medical Centre Mannheim, and retrospectively analyzed...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28740960/prognostic-factors-in-patients-with-acute-mesenteric-ischemia
#13
Doğan Yıldırım, Adnan Hut, Cihad Tatar, Turgut Dönmez, Muzaffer Akıncı, Mehmet Toptaş
OBJECTIVE: Acute mesenteric ischemia, one of the causes of acute abdominal pain due to occlusion of the superior mesenteric artery, has a fatal course as a result of intestinal necrosis. There is no specific laboratory test to diagnose acute mesenteric ischemia. The basis of treatment in cases of acute mesenteric ischemia is composed of early diagnosis, resection of intestinal sections with infarction, regulation of intestinal blood flow, second look laparotomy when required, and intensive care support...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28680357/direct-estimation-of-reference-intervals-for-thyroid-parameters-in-the-republic-of-srpska
#14
Bosa Mirjanic-Azaric, Sanja Avram, Tanja Stojakovic-Jelisavac, Darja Stojanovic, Mira Petkovic, Natasa Bogavac-Stanojevic, Svetlana Ignjatovic, Marina Stojanov
BACKGROUND: The aim of this study was to determine the reference values for thyrotropin (TSH), thyroid hormones (total and free thyroxine, T4 and fT4; total and free triiodothyronine, T3 and fT3), thyroglobulin (Tg) and thyroid antibodies (thyroid peroxidase, TPOAb and thyroglobulin antibody, TgAb) in the population of the Republic of Srpska. METHODS: A total of 250 euthyroid subjects were enrolled in this study. A direct method for choosing reference subjects was used to establish reference intervals...
April 2017: Journal of Medical Biochemistry
https://www.readbyqxmd.com/read/28675449/evaluation-of-the-accuracy-of-nine-electronic-apex-locators-by-using-micro-ct
#15
T Connert, M S Judenhofer, M Hülber-J, S Schell, J G Mannheim, B J Pichler, C Löst, A ElAyouti
AIM: To determine the accuracy of locating the apical constriction using apex locators. METHODOLOGY: Extracted teeth were micro-CT scanned preoperatively to localize the apical constriction. Electronic length measurements of 91 root canals were made using nine electronic apex locators (EAL) connected to a mounting model. Distances from the major foramen were recorded at each scale bar of the EALs, and a file was fixed in the canal at a position indicated by each EAL to be the apical constriction...
July 4, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28659995/maxillary-overdenture-retained-with-an-implant-support-cad-cam-bar-a-4-years-follow-up-case
#16
Massimo Corsalini, Daniela Di Venere, Gianluca Stefanachi, Giovannino Muci, Andrea Palminteri, Alessandra Laforgia, Francesco Pettini
INTRODUCTION: Oral rehabilitation with overdenture on implants of upper jaw must be taken into consideration a variety of anatomical and biomechanical issues. It is possible to provide for rehabilitation with two or more implants, in different positions, solidarizing them with a bar. MATERIALS & METHODS: The present study involved a patient rehabilitated with 4 Xive implants (Friadent GmbH, Mannheim, Germany) solidarized with a titanium bar crafted with CAD-CAM technology for maximal comfort, precision and structural lightness...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28606430/long-term-results-after-endoscopic-drainage-of-pancreatic-pseudocysts-a-single-center-experience
#17
Felix Rückert, Anja Lietzmann, Torsten J Wilhelm, Moritz Sold, Georg Kähler, Alexander Schneider
BACKGROUND: Pancreatic pseudocysts (PPC) are collections of fluid encapsulated within a well-defined inflammatory wall that develop during pancreatic inflammation. Internal drainage represents the standard of care in lesions that persist and lead to symptoms and complications. Only limited data are available on long-term results and recurrence of PPC after drainage procedures. Thus, the aim of the present study was to analyse the long-term outcome after endoscopic drainage of PPC. MATERIAL AND METHODS: Patient data were retrospectively collected by review of clinical records of the University Medical Center Mannheim...
July 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28600609/-gerontologically-oriented-study-programs-in-germany-critical-review
#18
REVIEW
Eva-Marie Kessler, Andreas Hoff, Annette Franke
The objective of this article is a state-of-the-art analysis and critical reflection of the status quo of gerontologically oriented study programs in higher education in Germany. The major impulse for writing this article was provided by the newly established working group "Gerontological Education", which was inaugurated at the joint annual conference of sections III and IV of the German Society of Gerontology and Geriatrics in Mannheim in 2015. A systematic review of gerontological study programs shows that the number of such programs has increased in Germany over the past decade...
June 9, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28584870/the-inventory-as-a-core-element-in-the-further-development-of-the-science-curriculum-in-the-mannheim-reformed-curriculum-of-medicine
#19
Julia Eckel, Katrin Schüttpelz-Brauns, Thomas Miethke, Alexandra Rolletschek, Harald M Fritz
Introduction: The German Council of Science and Humanities as well as a number of medical professional associations support the strengthening of scientific competences by developing longitudinal curricula for teaching scientific competences in the undergraduate medical education. The National Competence Based Catalogue of Learning Objectives for Undergraduate Medical Education (NKLM) has also defined medical scientific skills as learning objectives in addition to the role of the scholar. The development of the Mannheim science curriculum started with a systematic inventory of the teaching of scientific competences in the Mannheim Reformed Curriculum of Medicine (MaReCuM)...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/28579785/dexmedetomidine-for-the-management-of-postictal-agitation-after-electroconvulsive-therapy-with-s-ketamine-anesthesia
#20
Suna Su Aksay, Jan Malte Bumb, Dmitry Remennik, Manfred Thiel, Laura Kranaster, Alexander Sartorius, Christoph Janke
OBJECTIVES: Postictal agitation (PIA) represents one of the most common complications during a modified electroconvulsive therapy (ECT) course. Its clinical management can be challenging especially in cases with poor response to benzodiazepines. Dexmedetomidine, a highly selective alpha-2 adrenoceptor agonist acting predominantly in the locus coeruleus, exerts sedative effects without causing relevant respiratory depression. To the best of our knowledge, this is the first study that aimed to assess the impact of dexmedetomidine use with S-ketamine anesthesia on PIA reduction in ECT...
2017: Neuropsychiatric Disease and Treatment
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