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https://www.readbyqxmd.com/read/28680357/direct-estimation-of-reference-intervals-for-thyroid-parameters-in-the-republic-of-srpska
#1
Bosa Mirjanic-Azaric, Sanja Avram, Tanja Stojakovic-Jelisavac, Darja Stojanovic, Mira Petkovic, Natasa Bogavac-Stanojevic, Svetlana Ignjatovic, Marina Stojanov
BACKGROUND: The aim of this study was to determine the reference values for thyrotropin (TSH), thyroid hormones (total and free thyroxine, T4 and fT4; total and free triiodothyronine, T3 and fT3), thyroglobulin (Tg) and thyroid antibodies (thyroid peroxidase, TPOAb and thyroglobulin antibody, TgAb) in the population of the Republic of Srpska. METHODS: A total of 250 euthyroid subjects were enrolled in this study. A direct method for choosing reference subjects was used to establish reference intervals...
April 2017: Journal of Medical Biochemistry
https://www.readbyqxmd.com/read/28675449/evaluation-of-the-accuracy-of-nine-electronic-apex-locators-by-using-micro-ct
#2
T Connert, M S Judenhofer, M Hülber-J, S Schell, J G Mannheim, B J Pichler, C Löst, A ElAyouti
AIM: To determine the accuracy of locating the apical constriction using apex locators. METHODOLOGY: Extracted teeth were micro-CT scanned preoperatively to localize the apical constriction. Electronic length measurements of 91 root canals were performed using nine electronic apex locators (EAL) connected to a mounting model. Distances from the major foramen were recorded at each scale-bar of the EALs and a file was fixed in the canal at a position indicated by EAL to be the apical constriction...
July 4, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28659995/maxillary-overdenture-retained-with-an-implant-support-cad-cam-bar-a-4-years-follow-up-case
#3
Massimo Corsalini, Daniela Di Venere, Gianluca Stefanachi, Giovannino Muci, Andrea Palminteri, Alessandra Laforgia, Francesco Pettini
INTRODUCTION: Oral rehabilitation with overdenture on implants of upper jaw must be taken into consideration a variety of anatomical and biomechanical issues. It is possible to provide for rehabilitation with two or more implants, in different positions, solidarizing them with a bar. MATERIALS & METHODS: The present study involved a patient rehabilitated with 4 Xive implants (Friadent GmbH, Mannheim, Germany) solidarized with a titanium bar crafted with CAD-CAM technology for maximal comfort, precision and structural lightness...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28606430/long-term-results-after-endoscopic-drainage-of-pancreatic-pseudocysts-a-single-center-experience
#4
Felix Rückert, Anja Lietzmann, Torsten J Wilhelm, Moritz Sold, Georg Kähler, Alexander Schneider
BACKGROUND: Pancreatic pseudocysts (PPC) are collections of fluid encapsulated within a well-defined inflammatory wall that develop during pancreatic inflammation. Internal drainage represents the standard of care in lesions that persist and lead to symptoms and complications. Only limited data are available on long-term results and recurrence of PPC after drainage procedures. Thus, the aim of the present study was to analyse the long-term outcome after endoscopic drainage of PPC. MATERIAL AND METHODS: Patient data were retrospectively collected by review of clinical records of the University Medical Center Mannheim...
June 3, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28600609/-gerontologically-oriented-study-programs-in-germany-critical-review
#5
REVIEW
Eva-Marie Kessler, Andreas Hoff, Annette Franke
The objective of this article is a state-of-the-art analysis and critical reflection of the status quo of gerontologically oriented study programs in higher education in Germany. The major impulse for writing this article was provided by the newly established working group "Gerontological Education", which was inaugurated at the joint annual conference of sections III and IV of the German Society of Gerontology and Geriatrics in Mannheim in 2015. A systematic review of gerontological study programs shows that the number of such programs has increased in Germany over the past decade...
June 9, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28584870/the-inventory-as-a-core-element-in-the-further-development-of-the-science-curriculum-in-the-mannheim-reformed-curriculum-of-medicine
#6
Julia Eckel, Katrin Schüttpelz-Brauns, Thomas Miethke, Alexandra Rolletschek, Harald M Fritz
Introduction: The German Council of Science and Humanities as well as a number of medical professional associations support the strengthening of scientific competences by developing longitudinal curricula for teaching scientific competences in the undergraduate medical education. The National Competence Based Catalogue of Learning Objectives for Undergraduate Medical Education (NKLM) has also defined medical scientific skills as learning objectives in addition to the role of the scholar. The development of the Mannheim science curriculum started with a systematic inventory of the teaching of scientific competences in the Mannheim Reformed Curriculum of Medicine (MaReCuM)...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/28579785/dexmedetomidine-for-the-management-of-postictal-agitation-after-electroconvulsive-therapy-with-s-ketamine-anesthesia
#7
Suna Su Aksay, Jan Malte Bumb, Dmitry Remennik, Manfred Thiel, Laura Kranaster, Alexander Sartorius, Christoph Janke
OBJECTIVES: Postictal agitation (PIA) represents one of the most common complications during a modified electroconvulsive therapy (ECT) course. Its clinical management can be challenging especially in cases with poor response to benzodiazepines. Dexmedetomidine, a highly selective alpha-2 adrenoceptor agonist acting predominantly in the locus coeruleus, exerts sedative effects without causing relevant respiratory depression. To the best of our knowledge, this is the first study that aimed to assess the impact of dexmedetomidine use with S-ketamine anesthesia on PIA reduction in ECT...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28578543/lessons-learned-from-the-implementation-of-seek-test-treat-retain-interventions-using-mobile-phones-and-text-messaging-to-improve-engagement-in-hiv-care-for-vulnerable-populations-in-the-united-states
#8
Katerina A Christopoulos, William E Cunningham, Curt G Beckwith, Irene Kuo, Carol E Golin, Kevin Knight, Patrick M Flynn, Anne C Spaulding, Lara S Coffin, Bridget Kruszka, Ann Kurth, Jeremy D Young, Sharon Mannheimer, Heidi M Crane, Shoshana Y Kahana
In the United States, little is known about interventions that rely on mobile phones and/or text messaging to improve engagement in HIV care for vulnerable populations. Domestic studies using these technologies as part of the National Institute on Drug Abuse "Seek, Test, Treat, Retain" research initiative were queried regarding intervention components, implementation issues, participant characteristics, and descriptive statistics of mobile phone service delivery. Across five studies with 1,135 predominantly male, minority participants, implementation challenges occurred in three categories: (1) service interruptions; (2) billing/overage issues, and; (3) the participant user experience...
June 3, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28554369/effects-and-mediators-of-psychosocial-work-characteristics-on-somatic-symptoms-six-years-later-prospective-findings-from-the-mannheim-industrial-cohort-studies-mics
#9
Raphael M Herr, Jian Li, Adrian Loerbroks, Peter Angerer, Johannes Siegrist, Joachim E Fischer
OBJECTIVE: Ample evidence documented the adverse health effects of work stressors, and recent research has increasingly focused on somatic symptoms which are very common and costly. Prospective evidence is however sparse and yielded mixed findings. Furthermore, there is reason to assume that depression and anxiety might mediate the effects of adverse psychosocial work conditions on somatic symptoms. This study aimed to investigate longitudinal effects of work stressors on somatic symptoms and the potential mediation by anxiety and/or depression...
July 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28513115/endarterectomy-or-stenting-in-severe-asymptomatic-carotid-stenosis
#10
Dallit Mannheim, Batla Falah, Ron Karmeli
BACKGROUND: Stroke is a major cause of death in the western world, and carotid endarterectomy has been shown to be effective in treating both symptomatic and asymptomatic carotid stenosis. Carotid stenting is a relatively new form of treatment for carotid stenosis and few studies have looked specifically at asymptomatic patients. OBJECTIVES: To retrospectively examine short- and long-term results in the treatment of asymptomatic carotid artery stenosis with surgery or stenting...
May 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28498805/foxm1-predicts-overall-and-disease-specific-survival-in-muscle-invasive-urothelial-carcinoma-and-presents-a-differential-expression-between-bladder-cancer-subtypes
#11
Sebastien Rinaldetti, Ralph Markus Wirtz, Thomas Stefan Worst, Markus Eckstein, Cleo Aaron Weiss, Johannes Breyer, Wolfgang Otto, Christian Bolenz, Arndt Hartmann, Philipp Erben
Forkhead box M1 (FOXM1) is a late cell cycle gene that plays a crucial role in carcinogenesis and chemotherapeutic drug resistance. In this study, the impact of FOXM1 expression on patient outcome was investigated for the first time in formalin fixed and paraffin embedded (FFPE) samples of chemotherapy naïve muscle-invasive bladder cancer (MIBC) patients. Expression analyses were performed on the Mannheim cohort (n=84) and validated on the independent Chungbuk cohort (n=61). In a Cox' proportional hazards model, a distinct FOXM1 expression cut-off dividing both cohorts in a 'high-risk' and 'low-risk' group has been determined...
April 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28488340/abstracts-for-the-31st-european-immunogenetics-and-histocompatibility-conference-efi-25th-annual-meeting-of-the-german-society-for-immunogenetics-dgi-mannheim-heidelberg-germany-30-may-2-june-2017
#12
https://www.readbyqxmd.com/read/28453877/asymmetric-changes-in-circulating-insulin-levels-after-an-increase-compared-with-a-reduction-in-insulin-pump-basal-rate-in-people-with-type-1-diabetes
#13
S A McAuley, G M Ward, J C Horsburgh, J L Gooley, A J Jenkins, R J MacIsaac, D N O'Neal
AIMS: To investigate circulating insulin profiles after a clinically relevant insulin pump basal rate increase vs a reduction, and the associated glucose responses. METHODS: A cohort of 12 adults with Type 1 diabetes undertook this two-stage university hospital study using Accu-Chek pumps (Roche Diagnostics, Mannheim, Germany) and insulin aspart. An insulin basal rate change of 0.2 unit/h (increase in first stage, reduction in second stage) was implemented at ~09:30 h, after a single overnight basal rate (without bolus insulin), while fasting participants rested...
April 28, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28434885/early-performance-on-an-eye-surgery-simulator-predicts-subsequent-resident-surgical-performance
#14
Ramak Roohipoor, Mehdi Yaseri, Amir Teymourpour, Carolyn Kloek, John B Miller, John I Loewenstein
OBJECTIVE: To examine early performance on an eye surgery simulator and its relationship to subsequent live surgical performance in a single large residency program. DESIGN: Retrospective study. SETTING: Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology. METHODS: In a retrospective study, we compared performance of 30 first-year ophthalmology residents on an eye surgery simulator to their surgical skills as third-year residents...
April 20, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28421288/-83th-annual-meeting-of-the-german-cardiac-society-cardiac-and-circulation-research-april-19-22-2017-mannheim
#15
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28389778/resection-enterostomy-versus-hartmann-s-procedure-for-emergency-colonic-resections
#16
M Grott, K Horisberger, C Weiß, P Kienle, J Hardt
BACKGROUND: If a primary anastomosis is considered too risky after emergency colon resection either a resection enterostomy or an end stoma with closure of the distal bowel (Hartmann's procedure) is possible. This study analyzes the rate of restoration of intestinal continuity and other surgical outcomes after resection enterostomy placement versus Hartmann's procedure for emergency colon resections. METHODS: All patients who underwent emergency colorectal resections between August 2009 and June 2014 at the University Medical Center Mannheim were reviewed in regard to therapeutic approach, rate of restoration of bowel continuity, and surgical morbidity after the primary operation and after reversal surgery...
August 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28384058/analysis-of-hiv-integrase-resistance-in-black-men-who-have-sex-with-men-in-the-united-states
#17
Iris Chen, Yinfeng Zhang, Vanessa Cummings, Gavin A Cloherty, Matthew Connor, Geetha Beauchamp, Sam Griffith, Scott Rose, Joel Gallant, Hyman M Scott, Steven Shoptaw, Carlos Del Rio, Irene Kuo, Sharon Mannheimer, Hong-Van Tieu, Christopher B Hurt, Sheldon D Fields, Darrell P Wheeler, Kenneth H Mayer, Beryl A Koblin, Susan H Eshleman
Resistance to reverse transcriptase and protease inhibitors was frequently detected in HIV from black men who have sex with men (MSM) enrolled in the HIV prevention trials network (HPTN) 061 study. In this study, integrase strand transfer inhibitor (INSTI) resistance was analyzed in black MSM enrolled in HPTN 061 (134 infected at enrollment and 23 seroconverters) and a follow-up study, HPTN 073 (eight seroconverters). The ViroSeq HIV-1 Integrase Genotyping Kit (Abbott Molecular) was used for analysis. Major INSTI resistance mutations were not detected in any of the samples...
July 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28376791/definition-of-common-carotid-wall-thickness-affects-risk-classification-in-relation-to-degree-of-internal-carotid-artery-stenosis-the-plaque-at-risk-parisk-study
#18
J Steinbuch, A C van Dijk, Fhbm Schreuder, Mtb Truijman, J Hendrikse, P J Nederkoorn, A van der Lugt, E Hermeling, Apg Hoeks, W H Mess
BACKGROUND: Mean or maximal intima-media thickness (IMT) is commonly used as surrogate endpoint in intervention studies. However, the effect of normalization by surrounding or median IMT or by diameter is unknown. In addition, it is unclear whether IMT inhomogeneity is a useful predictor beyond common wall parameters like maximal wall thickness, either absolute or normalized to IMT or lumen size. We investigated the interrelationship of common carotid artery (CCA) thickness parameters and their association with the ipsilateral internal carotid artery (ICA) stenosis degree...
April 4, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28361250/influence-of-co-57-and-ct-transmission-measurements-on-the-quantification-accuracy-and-partial-volume-effect-of-a-small-animal-pet-scanner
#19
Julia G Mannheim, Andreas M Schmid, Bernd J Pichler
PURPOSE: Non-invasive in vivo positron emission tomography (PET) provides high detection sensitivity in the nano- to picomolar range and in addition to other advantages, the possibility to absolutely quantify the acquired data. The present study focuses on the comparison of transmission data acquired with an X-ray computed tomography (CT) scanner or a Co-57 source for the Inveon small animal PET scanner (Siemens Healthcare, Knoxville, TN, USA), as well as determines their influences on the quantification accuracy and partial volume effect (PVE)...
March 30, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28352984/a-longitudinal-analysis-of-treatment-optimism-and-hiv-acquisition-and-transmission-risk-behaviors-among-black-men-who-have-sex-with-men-in-hptn-061
#20
Matthew E Levy, Gregory Phillips, Manya Magnus, Irene Kuo, Geetha Beauchamp, Lynda Emel, Christopher Hucks-Ortiz, Erica L Hamilton, Leo Wilton, Iris Chen, Sharon Mannheimer, Hong-Van Tieu, Hyman Scott, Sheldon D Fields, Carlos Del Rio, Steven Shoptaw, Kenneth Mayer
Little is known about HIV treatment optimism and risk behaviors among Black men who have sex with men (BMSM). Using longitudinal data from BMSM in the HPTN 061 study, we examined participants' self-reported comfort with having condomless sex due to optimistic beliefs regarding HIV treatment. We assessed correlates of treatment optimism and its association with subsequent risk behaviors for HIV acquisition or transmission using multivariable logistic regression with generalized estimating equations. Independent correlates of treatment optimism included age ≥35 years, annual household income <$20,000, depressive symptoms, high HIV conspiracy beliefs, problematic alcohol use, and previous HIV diagnosis...
March 28, 2017: AIDS and Behavior
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