A Pileri, C Agostinelli, F Fuligni, A Broccoli, S Gunnella, E Sabattini, V Grandi, A Guglielmo, P L Zinzani, A Patrizi, N Pimpinelli
Peripheral T-cell lymphomas not otherwise specified (PTCLs-NOS) have been defined as a kind of "Pandora's box", because of the broad morphologic spectrum, which features a prevalent nodal involvement and an aggressive, yet non-specific clinical course1,2 . PTCLs-NOS usually have a nodal presentation, while a skin spread occurs in approximately 20% of cases3 being regarded as a worse prognostic factor4,5,6 . PTCLs-NOS featuring skin lesions present at least six months before a hypothetical systemic involvement are regarded as a separate entity, named primary cutaneous PTCLs-NOS (PC-PTCLs-NOS)3,4,7 ...
March 24, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV