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https://www.readbyqxmd.com/read/29628616/updates-on-uterine-artery-embolization
#1
REVIEW
Maureen P Kohi, James B Spies
Uterine fibroids (leiomyomas) are the most common benign neoplasm of the female pelvis and have a lifetime prevalence exceeding 80% among African American women and approaching 70% among Caucasian women. Approximately 50% of women with fibroids experience symptoms which may include menorrhagia that may result in anemia, bulk symptoms with bladder and bowel dysfunction and abdominal protrusion, dysmenorrhea, and infertility. Hysterectomy remains the most common treatment option for fibroids and concerns have been raised about the overuse of this procedure...
March 2018: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/29605409/effect-of-type-3-intramural-fibroids-on-in-vitro-fertilization-intracytoplasmic-sperm-injection-outcomes-a-retrospective-cohort-study
#2
Lei Yan, Qian Yu, Ya-Nan Zhang, Zizhen Guo, Zhongyuan Li, Jinlei Niu, Jinlong Ma
OBJECTIVE: To evaluate the influence of type 3 intramural fibroids on in vitro fertilization-intracytoplasmic sperm injection (IVF-ICSI) outcomes. DESIGN: Retrospective cohort study. SETTING: University-based reproductive medicine center. PATIENT(S): All women undergoing IVF-ICSI from January 1, 2009, to December 31, 2016, in our unit. INTERVENTION(S): Each woman was matched with three separate control subjects of the same age (±1 year), number of cycles, type of infertility (primary or secondary), type of protocol used for controlled ovarian hyperstimulation (COH), and no uterine fibroids identified by transvaginal ultrasound...
March 28, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29564309/current-medical-treatment-of-uterine-fibroids
#3
REVIEW
Geum Seon Sohn, SiHyun Cho, Yong Man Kim, Chi-Heum Cho, Mee-Ran Kim, Sa Ra Lee
Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or recurrent pregnancy loss are generally associated with uterine fibroids. Although curative treatment of this tumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertility and avoid or delay surgery. The aim of this review is to provide available and emerging medical treatment options for symptomatic uterine fibroids...
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29555319/fertility-and-infertility-definition-and-epidemiology
#4
REVIEW
Mélodie Vander Borght, Christine Wyns
Infertility is a disease characterized by the failure to establish a clinical pregnancy after 12 months of regular and unprotected sexual intercourse. It is estimated to affect between 8 and 12% of reproductive-aged couples worldwide. Males are found to be solely responsible for 20-30% of infertility cases but contribute to 50% of cases overall. Secondary infertility is the most common form of female infertility around the globe, often due to reproductive tract infections. The three major factors influencing the spontaneous probability of conception are the time of unwanted non-conception, the age of the female partner and the disease-related infertility...
March 16, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29514385/analysis-of-presurgical-uterine-artery-embolization-puae-for-very-large-uterus-myomatosus-patient-s-desire-to-preserve-the-uterus-case-series-and-literature-review
#5
Dirk Schnapauff, Manon Russ, Thomas Kröncke, Matthias David
PURPOSE:  Purpose of this paper to present results of a group of 21 consecutive patients who underwent uterine artery embolization (UAE) immediately before myomectomy. Surgical myomectomy can lead to a substantial blood loss in case of large or multiple tumors due to the hypervascularization of the tumors. This may lead to multiple blood transfusion or hysterectomy. In cases were the preservation of the uterus is demanded, pre-operative embolization could reduce the risk of substantial bleeding...
March 7, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29483857/fertility-impairment-associated-with-uterine-fibroids-a-review-of-literature
#6
REVIEW
Marek Lisiecki, Maciej Paszkowski, Sławomir Woźniak
Uterine fibroids (also known as leiomyomas or myomas) are the most common benign tumors affecting reproductive organs in women. They are monoclonal tumors of the uterine smooth muscle, which spring from myometrium. It is estimated that they occur in 50-60% of the female population and rise to 70% by the age of 50. While mostly asymptomatic, myomas can be connected with several conditions, including abnormal bleeding with subsequent anemia, pelvic masses, pelvic pain, bulk symptoms, unfavorable impact on fertility and obstetric complications...
December 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29483856/ulipristal-acetate-as-a-treatment-option-for-uterine-fibroids
#7
REVIEW
Karolina Piecak, Paweł Milart, Ewa Woźniakowska, Tomasz Paszkowski
Uterine fibroids are the most common benign uterine tumours. Clinical symptoms include abnormal bleeding, pelvic pressure, pelvic pain, infertility and obstetric complications. Approximately one third of women with fibroids will require treatment. The management also depends on the number, size, and location of the fibroids. There are surgical and non-surgical treatment options. The choice of therapy depends on different factors, such as the severity of symptoms, tumour characteristics, age, and wish to preserve the uterus and fertility...
December 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29483855/the-role-of-levonorgestrel-intrauterine-systems-in-the-treatment-of-symptomatic-fibroids
#8
REVIEW
Wojciech Wrona, Anna Stępniak, Piotr Czuczwar
Uterine fibroids are considered to be the most frequently occurring tumours in females. The majority of fibroids do not require any treatment. When symptomatic, the major ailments include abnormal uterine bleeding, painful menstruation, pelvic pressure or pain, urinary problems, constipation, infertility, and recurrent pregnancy loss. Surgery remains a mainstay of symptomatic uterine fibroids therapy; however, minimally-invasive techniques and pharmacological management have become more available. The levonorgestrel intrauterine system (LNG-IUS) is a T-shaped device with a vertical stem containing a reservoir of levonorgestrel and is widely known for its contraception effect...
December 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29483852/3d-power-doppler-vascular-indices-as-a-novel-technique-in-assessing-the-outcome-of-minimally-invasive-techniques-in-uterine-fibroids-treatment
#9
REVIEW
Anna Stępniak, Piotr Czuczwar
Uterine fibroids are considered to be the most frequent female benign tumours. The most common reported symptoms of fibroids are heavy menstrual bleeding and painful menstruation, pelvic pain, urinary problems, constipation, as well as infertility and recurrent pregnancy loss. The mainstay of fibroid treatment is surgery, but nowadays minimally-invasive techniques are growing in popularity. Vascularity of fibroids may play a role in the outcome of these techniques, which is why it is important to find an objective, reproducible technique to measure the vascularization before and after the procedure...
December 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29432754/optimizing-research-in-symptomatic-uterine-fibroids-with-development-of-a-computable-phenotype-for-use-with-electronic-health-records
#10
Sarah R Hoffman, Anissa I Vines, Jacqueline R Halladay, Emily Pfaff, Lauren Schiff, Daniel Westreich, Aditi Sundaresan, La-Shell Johnson, Wanda K Nicholson
BACKGROUND: Women with symptomatic uterine fibroids can report a myriad of symptoms, including pain, bleeding, infertility, and psychosocial sequelae. Optimizing fibroid research requires the ability to enroll populations of women with image-confirmed symptomatic uterine fibroids. OBJECTIVE: Our objective was to develop an electronic health record-based algorithm to identify women with symptomatic uterine fibroids for a comparative effectiveness study of medical or surgical treatments on quality-of-life measures...
February 9, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29385977/abnormal-uterine-bleeding-managing-endometrial-dysfunction-and-leiomyomas
#11
Annabelle Brennan, Martha Hickey
Abnormal uterine bleeding refers to any change in the regularity, frequency, heaviness or length of menstruation. There are several potential causes for bleeding disturbance, the two most common being primary endometrial dysfunction and fibroids. Management of abnormal uterine bleeding involves both medical and surgical options and will largely depend on a patient's fertility plans. The use of levonorgestrel-releasing intrauterine devices for heavy menstrual bleeding is increasing in Australia, and they are considered first-line medical management for women accepting of hormonal therapies...
February 5, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29288921/outcome-of-magnetic-resonance-guided-focused-ultrasound-surgery-mrgfus-for-figo-class-1-fibroids
#12
Roy Mashiach, Yael Inbar, Jaron Rabinovici, Aya Mohr Sasson, Aviva Alagem-Mizrachi, Ronit Machtinger
OBJECTIVE: Intracavitary uterine fibroids and fibroids that distort the uterine cavity are associated with excessive vaginal bleeding and infertility. While intracavitary fibroids smaller than 4 cm are usually treated safely by operative hysteroscopy, larger fibroids may require multiple surgeries or more extensive surgery with possible damage to the integrity of the uterine wall. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a noninvasive approach for treating uterine fibroids, mainly the intramural type...
February 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29242974/effect-of-intramural-fibroid-on-uterine-and-endometrial-vascularity-in-infertile-women-scheduled-for-in-vitro-fertilization
#13
Ahmed Kamel, Akmal El-Mazny, Wafaa Ramadan, Suzy Abdelaziz, Sherine Gad-Allah, Hany Saad, Ahmed M Hussein, Emad Salah
PURPOSE: To study the effect of intramural fibroids on uterine and endometrial vascularity in infertile women scheduled for in-vitro fertilization (IVF). METHODS: 3D power Doppler was used to measure the endometrial volume and blood flow indices in 182 women with intramural fibroids not affecting the uterine cavity and compared them to a matched control group without fibroids. RESULTS: There was significantly increased vascularity in the endometrium of the fibroid group as denoted by higher endometrial VI (p = 0...
February 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29227848/development-and-evaluation-of-an-improved-laparoscopic-myomectomy-adopting-intracapsular-rotary-cut-procedures
#14
Shi-Lin Zhong, Li-Ping Zeng, Huan Li, Rui-Fang Wu
OBJECTIVES: To develop and evaluate the efficacy and feasibility of Intracapsular Rotary-cut Procedure (IRCP) in laparoscopic myomectomy (LM). STUDY DESIGN: It is a retrospective study conducted in Peking University Shenzhen Hospital (PUSH) in Shenzhen, China. A total of 96 patients who were treated with LM because of big and moderate size of myomas in PUSH from January 2013 and December 2015 were enrolled in this study. Among them 35 were managed with IRCP -integrated LM as the study group, while the other 61 were treated with normal LM as the control group...
February 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29208873/correlation-between-seropositivity-of-chlamydia-trachomatis-and-tubal-and-or-pelvic-pathology-detected-by-diagnostic-laparoscopy-in-subfertile-women
#15
N Begum, S A Anwary, M Alfazzaman, Z Mahzabin, F Deeba, M A Mostafa, M Akhter, M M Rahman
This prospective observational study was carried out in the Infertility Unit, Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from February 2011 to December 2013. Sixty-nine (69) subfertile women who were seropositive for Chlamydia Trachomatis were included in this study. Inclusion criteria was patients with sub-fertility having age between 22 and 40 years, seeking infertility treatment, normal ovarian function, all normozoospermic male partner, duration of infertility ranged from 1...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29186429/extracellular-matrix-in-uterine-leiomyoma-pathogenesis-a-potential-target-for-future-therapeutics
#16
REVIEW
Md Soriful Islam, Andrea Ciavattini, Felice Petraglia, Mario Castellucci, Pasquapina Ciarmela
BACKGROUND: Uterine leiomyoma (also known as fibroid or myoma) is the most common benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can produce serious clinical symptoms, including excessive uterine bleeding, pelvic pain or pressure, infertility and pregnancy complications. Due to lack of effective medical treatments surgery has been a definitive choice for the management of this tumor. OBJECTIVE AND RATIONALE: Extracellular matrix (ECM) accumulation and remodeling are thought to be crucial for fibrotic diseases such as uterine leiomyoma...
January 1, 2018: Human Reproduction Update
https://www.readbyqxmd.com/read/29166789/a-novel-approach-to-infertility-treatment-of-advance-age-patient-with-prominent-intramural-fibroid
#17
Raoul Orvieto, Eran Zilberberg, Valeria Stella Vanni, Amnom Botchan
We report for the first time on a case of infertile advance-age patient with large intramural fibroid, who conceived following a course of Ulipristal. The patient underwent two fresh fertility preserving IVF cycles, with cryopreservation of 9 day-3 embryos, followed by a 12 weeks course of Ulipristal (5 mg per day) and a subsequent frozen-thawed embryo transfer with her own previously cryopreserved embryos. We, therefore, believe that Ulipristal is a valuable addition to treatment armamentarium of advance-age infertile patient with prominent intramural fibroid...
November 22, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29157931/alternatives-to-hysterectomy-the-burden-of-fibroids-and-the-quality-of-life
#18
REVIEW
Chelsea Fortin, Rebecca Flyckt, Tommaso Falcone
Uterine fibroids are the most common benign tumor in reproductive-aged women. While the majority of women are asymptomatic, those with symptoms may suffer from abnormal uterine bleeding, infertility, pelvic pain or pressure, and urinary dysfunction. Fibroids represent a significant healthcare burden for women and society as a whole. Women with fibroids have compromised overall quality of life and impairment in many specific domains including work productivity, sexuality, self-image, relationships, and social emotional and physical well-being...
January 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29141456/increased-serum-levels-of-mbdnf-in-women-with-minimal-and-mild-endometriosis-have-no-predictive-power-for-the-disease
#19
Alexandra Perricos, Kazem Ashjaei, Heinrich Husslein, Katharina Proestling, Lorenz Kuessel, Reinhard Obwegeser, Rene Wenzl, Iveta Yotova
The objective of our pilot clinical, prospective study was to determine the serum levels of mature brain-derived neurotrophic factor, in of women with endometriosis and controls and explore whether mature brain-derived neurotrophic factor is a potential biomarker for the disease. The patients were selected from the Endometriosis Marker Austria prospective cohort study conducted at the tertiary referral certified Endometriosis Center of the Medical University of Vienna. All women underwent laparoscopic surgery because there was a suspicion of endometriosis, or the women had pelvic pain, adnexal cysts, unexplained infertility, or uterine fibroids...
January 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29139105/preoperative-medical-therapy-before-surgery-for-uterine-fibroids
#20
REVIEW
Anne Lethaby, Lucian Puscasiu, Beverley Vollenhoven
BACKGROUND: Uterine fibroids occur in up to 40% of women aged over 35 years. Some are asymptomatic, but up to 50% cause symptoms that warrant therapy. Symptoms include anaemia caused by heavy menstrual bleeding, pelvic pain, dysmenorrhoea, infertility and low quality of life. Surgery is the first choice of treatment. In recent years, medical therapies have been used before surgery to improve intraoperative and postoperative outcomes. However, such therapies tend to be expensive.Fibroid growth is stimulated by oestrogen...
November 15, 2017: Cochrane Database of Systematic Reviews
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