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https://www.readbyqxmd.com/read/28089575/association-of-uterine-fibroids-and-pregnancy-outcomes-after-ovarian-stimulation-intrauterine-insemination-for-unexplained-infertility
#1
Aaron K Styer, Susan Jin, Dan Liu, Baisong Wang, Alex J Polotsky, Mindy S Christianson, Wendy Vitek, Lawrence Engmann, Karl Hansen, Robert Wild, Richard S Legro, Christos Coutifaris, Ruben Alvero, Randal D Robinson, Peter Casson, Gregory M Christman, Alicia Christy, Michael P Diamond, Esther Eisenberg, Heping Zhang, Nanette Santoro
OBJECTIVE: To investigate the association of non-cavity-distorting uterine fibroids and pregnancy outcomes after ovarian stimulation-intrauterine insemination (OS-IUI) in couples with unexplained infertility. DESIGN: Secondary analysis from a prospective, randomized, multicenter clinical trial investigating fertility outcomes after OS-IUI. SETTING: Reproductive Medicine Network clinical sites. PATIENT(S): Nine hundred couples with unexplained infertility who participated in the Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation (AMIGOS) clinical trial...
January 12, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28063569/prise-en-charge-des-fibromes-ut%C3%A3-rins-en-pr%C3%A3-sence-d-une-infertilit%C3%A3-autrement-inexpliqu%C3%A3-e
#2
Belina Carranza-Mamane, Jon Havelock, Robert Hemmings
OBJECTIF: Formuler des recommandations quant à la façon optimale d'assurer la prise en charge des fibromes dans le contexte de l'infertilité. Les options habituelles et novatrices de prise en charge des fibromes seront analysées en mettant l'accent sur leur applicabilité chez les femmes qui souhaitent obtenir une grossesse. OPTIONS: La prise en charge des fibromes chez les femmes qui souhaitent obtenir une grossesse met d'abord en jeu la documentation de la présence des fibromes en question et la détermination de la probabilité que ces derniers affectent le potentiel génésique...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28024136/-new-methods-of-uterine-fibroids-treatment
#3
REVIEW
Aleksandra Marciniak, Iwona Szydłowska, Agnieszka Brodowska, Berenika Wiśniewska, Jolanta Nawrocka-Rutkowska, Andrzej Starczewski
Uterine fibroids are the most common benign tumors of the uterus. Their main symptoms are prolonged menstrual bleeding, leading over time to a secondary anemia, bleeding and spotting between periods, pelvic pain and infertility. It is recognized that fibroids are the most common indication for surgery in gynecology. Currently radical surgical treatment of fibroids is abandon. Ulipristalu acetate is used in pharmacological treatment. This medicine reduces the growth of fibroids. New non-invasive technique is also MR-guided focused ultrasound surgery using thermal tissue destruction by focusing ultrasound beam...
December 22, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28013320/angiogenesis-and-pro-angiogenic-factors-in-uterine-fibroids-facts-and-myths
#4
Monika Konarska, Anna Natalia Wrona, Veronika Aleksandrovych, Tomasz Bereza, Marek Sajewicz, Barbara Gach-Kuniewicz, Maciej Lis, Kinga Komnata, Mateusz Paziewski, Aleksandra Maleszka, Paweł Depukat, Bernard Solewski, Łukasz Warchoł
Uterine leiomyomata present major problem for females. Although they are benign tumors their frequency is associated with many symptoms like infertility, abdominal pain, menorrhagia. Authors based on their own morphological studies and review of the literature try to indicate main factors causing angiogenesis within leiomyomata and its influence on tumor growth. The strongest proangiogenic factor seems to be hypoxia, which stimulates up- and down-regulation of numerous genetically determined substances. Also mechanical pressure acting upon newly growing vessels is one of the factors which may determine formation of so called "vascular pseudocapsule" around the lesion...
2016: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/27966042/fertility-after-uterine-artery-embolization-for-symptomatic-multiple-fibroids-with-no-other-infertility-factors
#5
Antoine Torre, Arnaud Fauconnier, Vanessa Kahn, Olivier Limot, Laurence Bussierres, Jean Pierre Pelage
OBJECTIVES: To evaluate the fertility of women eligible for surgical multiple myomectomy, but who carefully elected a fertility-sparing uterine artery embolization (UAE). METHODS: Non-comparative open-label trial, on women ≤40 years, presenting with multiple symptomatic fibroids (at least 3, ≥3 cm), immediate pregnancy wish, and no associated infertility factor. Women had a bilateral limited UAE using tris-acryl gelatin microspheres ≥500 μm. Fertility, ovarian reserve, uterus and fibroid sizes, and quality of life questionnaires (UFS-QoL) were prospectively followed...
December 13, 2016: European Radiology
https://www.readbyqxmd.com/read/27965523/a-prospective-multicenter-registry-of-patients-undergoing-hysteroscopic-morcellation-of-uterine-polyps-and-myomas
#6
Michael D Scheiber, Serena H Chen
Background: Hysteroscopic morcellation removes uterine pathology under direct visualization with continuous real-time tissue fragment removal. Objective: The aim of this study was to explore the feasibility of hysteroscopic morcellation across a diverse set of facilities, including both surgical and office-based settings. Design: This was a prospective, single-arm, multicenter registry development (Canadian Task Force classification II-3). Materials and Methods: Thirty-four U.S. obstetrics and gynecology facilities enrolled subjects into the registry...
December 1, 2016: Journal of Gynecologic Surgery
https://www.readbyqxmd.com/read/27908602/kisspeptin-and-embryo-implantation-after-icsi
#7
Zehra Jamil, Syeda Sadia Fatima, Sara Arif, Faiza Alam, Rehana Rehman
A cross-sectional study was carried out at the Australian Concept Infertility Medical Centre from June 2014 to June 2015 to relate serum kisspeptin levels on human chorionic gonadotrophin (HCG) day with pregnancy outcome after intracytoplasmic sperm injection (ICSI). A total of 176 women aged 20 to 42 years, with regular menstrual cycles, normal thyroid function and prolactin levels selected for ICSI were included in the study. Patients with uterine fibroids, metabolic disorders, short agonist and antagonist protocol were excluded...
February 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/27898339/dietary-phytochemicals-for-possible-preventive-and-therapeutic-option-of-uterine-fibroids-signaling-pathways-as-target
#8
REVIEW
Md Soriful Islam, James H Segars, Mario Castellucci, Pasquapina Ciarmela
A growing interest has emerged on dietary phytochemicals to control diverse pathological conditions. Unfortunately, dietary phytochemical research in uterine fibroids is still under construction. Uterine fibroids/leiomyomas are benign tumors developing from the myometrium of the uterus in premenopausal women. They may occur in more than 70% of women, and approximately 25% of women show clinically significant symptoms. These include heavy and prolonged menstrual bleeding, pelvic pressure (urinary frequency, incontinence, and difficulty with urination), pelvic pain, pelvic mass, infertility, and reproductive dysfunction...
February 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/27867814/the-assessment-of-myometrium-perfusion-in-patients-with-uterine-fibroid-by-arterial-spin-labeling-mri
#9
Nozomi Takahashi, Osamu Yoshino, Osamu Hiraike, Eriko Maeda, Masanobu Nakamura, Masaaki Hori, Miyuki Harada, Kaori Koga, Shigeru Saito, Tomoyuki Fujii, Yutaka Osuga
BACKGROUND: It has been suggested that an inadequate blood supply caused by uterine fibroids may lead to decreasing fertility. Therefore, a quantitative evaluation of blood flow in the uterus might be a good tool for infertility treatments. For the first step, the ability to perform arterial spin labeling (ASL)-MRI in pelvic organs was examined by measuring blood flow in the uterine muscle layer. RESULTS: Three normal volunteer women, seven patients with one uterine fibroid and four patients treated with GnRH analogue for uterine fibroids, were enrolled in this study...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27843659/rare-case-of-leiomyoma-and-adenomyosis-in-mayer-rokitansky-kuster-hauser-syndrome
#10
P S Hoo, A R Norhaslinda, J N Shah Reza
We report a case of adenomyosis which developed from a hypoplastic uterus and leiomyoma in a patient with MRKH syndrome. A 45-year-old Malay female with primary amenorrhoea and primary infertility presented with abdominal mass and abdominal pain. She is phenotypically female, has well developed secondary sexual characteristics, and has normal female external genitalia with shallow vagina dimple. Transabdominal ultrasonography showed a homogenous adnexal mass of 10 × 8 cm, uterus sized 5 × 4 cm, and normal kidneys...
2016: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27780751/medicinal-plants-used-in-lesotho-for-treatment-of-reproductive-and-post-reproductive-problems
#11
A Moteetee, L Seleteng Kose
ETHNOPHARMACOLOGICAL RELEVANCE: Reproductive healthcare has been highlighted as a major challenge in Lesotho mainly due to the high prevalence of HIV/AIDS and sexually transmitted infections. As a result other reproductive ailments have not received much attention, particularly because healthcare facilities are already limited and many of them are inaccessible. For these reasons, medicinal plants play a major role in primary healthcare system in the country, in addition the plants are easily accessible, more affordable, and their use forms part of the cultural heritage...
December 24, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27668110/complex-laparoscopic-myomectomy-with-severe-adhesions-performed-with-proper-preventive-measures-and-power-morcellation-provides-a-safe-choice-in-certain-infertility-cases
#12
Jaime Alfaro-Alfaro, María de Los Ángeles Flores-Manzur, Roberto Nevarez-Bernal, Rodrigo Ayala-Yáñez
Laparoscopic myomectomy offers a real benefit to infertile patients with uterine fibroids and peritoneal adhesions. The procedure requires a skilled surgeon and laparoscopy technique to minimize adhesion formation and other proven benefits. Restrictions arise since this procedure requires power morcellation for fibroid tissue extraction. Two years ago, the Food and Drug Administration in the United States of America (FDA) issued the alert on power morcellation for uterine leiomyomas, addressing the risk of malignant cell spreading within the abdominal cavity (actual risk assessment from 1 in 360 to 1 in 7400 cases)...
2016: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27651652/efficacy-of-use-of-long-term-low-dose-mifepristone-for-the-treatment-of-fibroids
#13
Anupam Kapur, Ranjeeta Angomchanu, Madhusudan Dey
BACKGROUND: Fibroid or myoma is the commonest reported tumor of uterus, and is one of the important reasons for hysterectomy in our setting. Different drugs are available for medical management of fibroid uterus including mifepristone, a progesterone antagonist. Varying dosage regimen for mifepristone was studied as medical management of fibroid uterus. The aim of the project was to study the effect of mifepristone on the symptoms and size of fibroids, especially using a low-dose regimen for 6 months...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27651649/hysterolaparoscopy-in-the-evaluation-and-management-of-female-infertility
#14
Y M Kabadi, B Harsha
OBJECTIVE: To study the role of hysterolaparoscopy in the evaluation and management of female infertility. MATERIALS AND METHODS: A retrospective study of the 94 case files of all the patients who underwent diagnostic hysterolaparoscopy for infertility between January 2014 to June 2015 in the department of Obstetrics and Gynecology, Karnataka Institute of Medical Sciences, Hubli. These infertile women were confirmed to have normal ovulatory cycles, hormonal assays and seminogram report...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27651639/clinicopathological-study-of-uterine-leiomyomas-a-multicentric-study-in-rural-population
#15
Maitri Raghavendra Kulkarni, Indranil Dutta, Dilip Kumar Dutta
BACKGROUND AND OBJECTIVES: Leiomyoma of uterus forms the most common type of benign tumor of uterus and also the most common pelvic tumor in women. The symptomatology continues to be variable. Surgery has for long been the main mode of therapy for the myomas. For women who wish to retain the uterus for future pregnancies or other reasons, myomectomy is preferred. Recent trend has been toward nonsurgical approaches like GnRH hormone analogs/agonists, RU 486, or selective uterine artery embolization, laparoscopic cryoablation, radiofrequency thermal ablation, and MRGUs...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27647977/strong-association-between-endometriosis-and-symptomatic-leiomyomas
#16
Camran Nezhat, Anjie Li, Sozdar Abed, Erika Balassiano, Rose Soliemannjad, Azadeh Nezhat, Ceana H Nezhat, Farr Nezhat
BACKGROUND AND OBJECTIVES: The relationship between leiomyoma and endometriosis is poorly understood. Both contribute to considerable pain and may cause subfertility or infertility in women. We conducted this retrospective study to assess the rate of coexistence of endometriosis in women with symptomatic leiomyoma. The primary outcome measured was the coexistence of histology-proven endometriosis in women with symptomatic leiomyoma. METHODS: This is a retrospective review of a data-based collection of medical records of 244 patients treated at a tertiary medical center, who were evaluated for symptomatic leiomyoma from March 2011 through December 2015...
July 2016: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/27632930/laparoscopic-management-of-huge-myoma-nascendi
#17
Nuri Peker, Savas Gündoğan, Fatih Şendağ
STUDY OBJECTIVE: To demonstrate the feasibility of laparoscopic management of a huge myoma nascendi. DESIGN: Step-by-step video demonstration of the surgical procedure (Canadian Task Force classification III-C). SETTING: Uterine myoma is the most common benign neoplasm of the female reproductive tract, with an estimated incidence of 25% to 30% at reproductive age [1,2]. Patients generally have no symptoms; however, those with such symptoms as severe pelvic pain, heavy uterine bleeding, or infertility may be candidates for surgery...
September 12, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27632929/laparoscopic-management-of-huge-cervical-myoma
#18
Nuri Peker, Savaş Gündoğan, Fatih Şendağ
STUDY OBJECTIVE: To demonstrate the feasibility of laparoscopic management of a huge cervical myoma. DESIGN: Step-by-step video demonstration of the surgical procedure (Canadian Task Force classification III-C). SETTING: Uterine myoma is the most common benign neoplasm of the female reproductive tract, with an estimated incidence of 25% to 30% at reproductive age [1,2]. Patients generally have no symptoms; however, those with such symptoms as severe pelvic pain, heavy uterine bleeding, or infertility may be candidates for surgery...
September 12, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27466209/uterine-fibroid-management-from-the-present-to-the-future
#19
REVIEW
Jacques Donnez, Marie-Madeleine Dolmans
Uterine fibroids (also known as leiomyomas or myomas) are the most common form of benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses, pelvic pain, infertility, bulk symptoms and obstetric complications.Almost a third of women with leiomyomas will request treatment due to symptoms. Current management strategies mainly involve surgical interventions, but the choice of treatment is guided by patient's age and desire to preserve fertility or avoid 'radical' surgery such as hysterectomy...
November 2016: Human Reproduction Update
https://www.readbyqxmd.com/read/27449692/tips-for-safe-laparoscopic-multiple-myomectomy
#20
Suyash Naval, Rucha Naval, Sudarshan Naval, Jayshree Rane
STUDY OBJECTIVE: To demonstrate key steps in performing safe laparoscopic multiple myomectomy. DESIGN: Video focuses on stepwise description of all major steps of the surgical technique. PATIENT: Twenty-seven-year-old woman. Informed consent was taken from the subject, and the institutional review board approved this research. INTERVENTION: Laparoscopic multiple myomectomy with morcellation in bag. MEASUREMENTS AND MAIN RESULTS: About one-third of women with fibroids present with symptoms severe enough to warrant treatment...
July 20, 2016: Journal of Minimally Invasive Gynecology
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