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https://www.readbyqxmd.com/read/25054956/-the-inka-program-tailor-made-obstetric-analgesia
#1
REVIEW
A Pařízek
SETTING: Department of Obsterics and Gynecology 1st Faculty of Medicine, Charles University and General Faculty Hospital in Prague. OBJECTIVE: Predicting both the course of childbirth and the intensity of pain felt during childbirth is difficult, especially with first-time mothers. Some women tolerate birthing pains well, others require effective pain relief. Sometimes simple methods are enough, such as the presence of a partner, a relaxing atmosphere, massages, or walking, while other times the services of a birthing assistant or physician or even an anaesthesiologist are required...
June 2014: Ceská Gynekologie
https://www.readbyqxmd.com/read/578528/radioimmunoassay-for-normeperidine-studies-on-the-n-dealkylation-of-meperidine-and-anileridine
#2
D S Freeman, H B Gjika, H Van Vunakis
A sensitive and specific radioimmunoassay for normeperidine has been developed that can detect as little as 100 pg of this metabolite. In competitive binding experiments with [125I]O-tyramyl-normeperidinic acid and an antiserum produced in rabbits immunized with a bovine serum albumin-normeperidinic acid conjugate, meperidine is only 0.01% as effective an inhibitor as normeperidine. Therefore, normeperidine can be determined in physiological fluids and in tissue extracts when relatively large amounts of meperidine or other N-phenylpiperidine esters are present...
October 1977: Journal of Pharmacology and Experimental Therapeutics
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