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https://www.readbyqxmd.com/read/28916408/robot-assisted-kidney-transplantation-the-european-experience
#1
Alberto Breda, Angelo Territo, Luis Gausa, Volkan Tuğcu, Antonio Alcaraz, Mireia Musquera, Karel Decaestecker, Liesbeth Desender, Michael Stockle, Martin Janssen, Paolo Fornara, Nasreldin Mohammed, Giampaolo Siena, Sergio Serni, Luis Guirado, Carma Facundo, Nicolas Doumerc
BACKGROUND: Robot-assisted kidney transplantation (RAKT) has recently been introduced to reduce the morbidity of open kidney transplantation (KT). OBJECTIVE: To evaluate perioperative and early postoperative RAKT outcomes. DESIGN, SETTING AND PARTICIPANTS: This was a multicenter prospective observational study of 120 patients who underwent RAKT, predominantly with a living donor kidney, in eight European institutions between July 2015 and May 2017, with minimum follow-up of 1 mo...
September 12, 2017: European Urology
https://www.readbyqxmd.com/read/28915684/lack-of-association-between-nat2-polymorphism-and-prostate-cancer-risk-a-meta-analysis-and-trial-sequential-analysis
#2
Feng Wang, Zhiqiang Qin, Shuhui Si, Jingyuan Tang, Lingyan Xu, Haoxiang Xu, Ran Li, Peng Han, Haiwei Yang
Previous studies have investigated the association between NAT2 polymorphism and the risk of prostate cancer (PCa). However, the findings from these studies remained inconsistent. Hence, we performed a meta-analysis to provide a more reliable conclusion about such associations. In the present meta-analysis, 13 independent case-control studies were included with a total of 14,469 PCa patients and 10,689 controls. All relevant studies published were searched in the databates PubMed, EMBASE, and Web of Science, till March 1st, 2017...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28914976/haloperidol-versus-5-ht3-receptor-antagonists-for-postoperative-vomiting-and-qtc-prolongation-a-noninferiority-meta-analysis-and-trial-sequential-analysis-of-randomized-controlled-trials
#3
REVIEW
Preet Mohinder Singh, Anuradha Borle, Jeetinder Kaur Makkar, Anjan Trikha, David Fish, Ashish Sinha
Haloperidol is an antipsychotic with well-known antiemetic potential. It is underutilized for postoperative nausea vomiting due to reported corrected QT interval (QTc) prolongation. This meta-analysis evaluates its safety and efficacy as an antiemetic in the perioperative period. Trials comparing haloperidol to 5-HT3 -receptor antagonists (5-HT3 -RA) for 24 postoperative vomiting incidences published up to May 2017 were searched in the medical database. Comparisons were made for antiemetic efficiency variables (vomiting incidence, rescue antiemetic need, and patients with complete response) during early (until 6 hours) and late postoperative phases...
September 15, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28914229/clinical-effectiveness-and-cost-effectiveness-of-beta-interferon-and-glatiramer-acetate-for-treating-multiple-sclerosis-systematic-review-and-economic-evaluation
#4
G J Melendez-Torres, Peter Auguste, Xavier Armoiry, Hendramoorthy Maheswaran, Rachel Court, Jason Madan, Alan Kan, Stephanie Lin, Carl Counsell, Jacoby Patterson, Jeremy Rodrigues, Olga Ciccarelli, Hannah Fraser, Aileen Clarke
BACKGROUND: At the time of publication of the most recent National Institute for Health and Care Excellence (NICE) guidance [technology appraisal (TA) 32] in 2002 on beta-interferon (IFN-β) and glatiramer acetate (GA) for multiple sclerosis, there was insufficient evidence of their clinical effectiveness and cost-effectiveness. OBJECTIVES: To undertake (1) systematic reviews of the clinical effectiveness and cost-effectiveness of IFN-β and GA in relapsing-remitting multiple sclerosis (RRMS), secondary progressive multiple sclerosis (SPMS) and clinically isolated syndrome (CIS) compared with best supportive care (BSC) and each other, investigating annualised relapse rate (ARR) and time to disability progression confirmed at 3 months and 6 months and (2) cost-effectiveness assessments of disease-modifying therapies (DMTs) for CIS and RRMS compared with BSC and each other...
September 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28910279/longitudinal-multiparameter-single-cell-analysis-of-macaques-immunized-with-pneumococcal-protein-conjugated-or-unconjugated-polysaccharide-vaccines-reveals-distinct-antigen-specific-memory-b-cell-repertoires
#5
Bin Jia, Lisa K McNeil, Christopher D Dupont, Konstantinos Tsioris, Rachel M Barry, Ingrid L Scully, Adebola O Ogunniyi, Christopher Gonzalez, Michael W Pride, Todd M Gierahn, Paul A Liberator, Kathrin U Jansen, J Christopher Love
BACKGROUND: The efficacy of protein-conjugated pneumococcal polysaccharide vaccines has been well characterized for children. The level of protection conferred by unconjugated polysaccharide vaccines remains less clear, particularly for elderly individuals who have had prior antigenic experience through immunization with unconjugated polysaccharide vaccines or natural exposure to Streptococcus pneumoniae. METHODS: We compared the magnitude, diversity and genetic biases of antigen-specific memory B cells in two groups of adult cynomolgus macaques that were immunized with a 7-valent conjugated vaccine and boosted after five years with either a 13-valent pneumococcal polysaccharide conjugate vaccine (13vPnC) or a 23-valent unconjugated pneumococcal polysaccharide vaccine (23vPS) using microengraving (a single-cell analysis method) and single-cell RT-PCR...
2017: PloS One
https://www.readbyqxmd.com/read/28906372/efficacy-and-safety-of-laparoscopic-bile-duct-exploration-versus-endoscopic-sphincterotomy-for-concomitant-gallstones-and-common-bile-duct-stones-a-meta-analysis-of-randomized-controlled-trials
#6
Ying-Chao Gao, Jinjun Chen, Qiyu Qin, Hu Chen, Wei Wang, Jian Zhao, Fulong Miao, Xin Shi
BACKGROUND: The purpose of this study was to compare the efficacy and safety of laparoscopic cholecystectomy (LC) plus laparoscopic common bile duct (CBD) stones exploration (LCBDE) with LC plus endoscopic sphincterotomy (EST) in the treatment of patients with gallstones and CBD stones. METHODS: The authors searched PubMed, Web of Science, and Embase to identify relevant studies. Risk ratios (RRs) were pooled to compare stone clear, retained stone, conversion to other procedures, and complications...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28905212/hub-and-spoke-stroke-network-in-the-veneto-region-a-retrospective-study-investigating-the-effectiveness-of-the-stroke-pathway-and-trends-over-time
#7
L Nardetto, B Giometto, G Moretto, D Mantoan, M Saia
After recognizing the pivotal role played by stroke unit (SU) admission in reducing mortality and dependency in stroke patients, the need to organize and monitor stroke networks has become an increasingly essential aspect of stroke care. We conducted a retrospective study of stroke patients admitted to hospitals in the Veneto region from 2007 to 2015 in order to evaluate the effectiveness of the stroke pathway and trends over time. Between 2007 and 2015, 61,062 stroke patients were discharged from Veneto hospitals: they were more frequently female, females were older than males, and had higher intrahospital mortality and a lower probability of undergoing systemic thrombolysis...
September 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28904507/adjunctive-melatonin-for-tardive-dyskinesia-in-patients-with-schizophrenia-a-meta-analysis
#8
Chen-Hui Sun, Wei Zheng, Xin-Hu Yang, Dong-Bin Cai, Chee H Ng, Gabor S Ungvari, Hai-Yan Li, Yu-Jie Wu, Yu-Ping Ning, Yu-Tao Xiang
BACKGROUND: Tardive dyskinesia (TD) is characterized by abnormal and involuntary movements. Importantly, TD could cause considerable personal suffering and social and physical disabilities. AIMS: This meta-analysis based on randomized controlled trials (RCTs) systematically assessed the therapeutic effect and tolerability of melatonin for TD in schizophrenia. METHODS: A computerized and systematical search of both Chinese (Wanfang Data, Chinese National Knowledge Infrastructure (CNKI), SINOMED) and English (PubMed, PsycINFO, Embase, Cochrane Library databases) databases, from their inception until June 8, 2017, was conducted by two independent authors...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28903634/the-dynamics-of-compensation-when-ingroup-favoritism-paves-the-way-for-outgroup-praise
#9
Vincent Yzerbyt, Laurent Cambon
Compensation research suggests that when people evaluate their own and another group, the search for positive differentiation fuels the emergence of compensatory ratings on the two fundamental dimensions of social perception, competence and warmth. In two experiments, we tested whether obstacles to positive differentiation on the preferred dimension disrupted compensation. Both experiments showed that high-status (low-status) group members grant the outgroup a higher standing on warmth (competence) when positive differentiation can be achieved on the orthogonal dimension, competence (warmth)...
May 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28903473/baseline-anatomical-assessment-of-the-uterus-and-ovaries-in-infertile-women-a-systematic-review-of-the-evidence-on-which-assessment-methods-are-the-safest-and-most-effective-in-terms-of-improving-fertility-outcomes
#10
Sarah C Armstrong, Marian Showell, Elizabeth A Stewart, Robert W Rebar, Sheryl Vanderpoel, Cynthia M Farquhar
BACKGROUND: This review focuses on the initial presentation of women who suspect that they are infertile, and how best to assess the anatomy of their uterus and ovaries in order to investigate the cause of their infertility, and potentially improve desired fertility outcomes. This review was undertaken as part of a World Health Organization initiative to assess the evidence available to address guidance for the diagnosis and treatment of infertility within a global context. Providing access to care for infertile women will help to ease the psycho-social burdens, such as ostracization, intimate partner violence and other negative consequences of being involuntarily childless or unable to become pregnant despite desiring a biological child or children...
September 1, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28902922/molecular-clustering-of-patients-with-diabetes-and-pulmonary-tuberculosis-a-systematic-review-and-meta-analysis
#11
Francles Blanco-Guillot, Guadalupe Delgado-Sánchez, Norma Mongua-Rodríguez, Pablo Cruz-Hervert, Leticia Ferreyra-Reyes, Elizabeth Ferreira-Guerrero, Mercedes Yanes-Lane, Rogelio Montero-Campos, Miriam Bobadilla-Del-Valle, Pedro Torres-González, Alfredo Ponce-de-León, José Sifuentes-Osornio, Lourdes Garcia-Garcia
INTRODUCTION: Many studies have explored the relationship between diabetes mellitus (DM) and tuberculosis (TB) demonstrating increased risk of TB among patients with DM and poor prognosis of patients suffering from the association of DM/TB. Owing to a paucity of studies addressing this question, it remains unclear whether patients with DM and TB are more likely than TB patients without DM to be grouped into molecular clusters defined according to the genotype of the infecting Mycobacterium tuberculosis bacillus...
2017: PloS One
https://www.readbyqxmd.com/read/28902069/antiinflammatory-strategies-in-intrahepatic-islet-transplantation-a-comparative-study-in-preclinical-models
#12
A Citro, E Cantarelli, S Pellegrini, E Dugnani, L Piemonti
BACKGROUND: The identification of pathway(s) playing a pivotal role in peritransplant detrimental inflammatory events represents the crucial step towards a better management and outcome of pancreatic islet transplanted patients. Recently, we candidate the CXCR1/2 inhibition as a relevant strategy in enhancing pancreatic islet survival after transplantation. METHODS: Here, the most clinically used antiinflammatory compounds (IL1-receptor antagonist, steroids and TNF-α inhibitor) alone or in combination with a CXCR1/2 inhibitor were evaluated in their ability to improve engraftment or delay graft rejection...
September 8, 2017: Transplantation
https://www.readbyqxmd.com/read/28901172/traditional-manual-acupuncture-combined-with-rehabilitation-therapy-for-shoulder-hand-syndrome-after-stroke-within-the-chinese-healthcare-system-a-systematic-review-and-meta-analysis
#13
Le Peng, Chao Zhang, Lan Zhou, Hong-Xia Zuo, Xiao-Kuo He, Yu-Ming Niu
OBJECTIVE: To investigate the effectiveness of traditional manual acupuncture combined with rehabilitation therapy versus rehabilitation therapy alone for shoulder hand syndrome after stroke. DATA SOURCES: PubMed, EMBASE, the Cochrane Library, Chinese Biomedicine Database, China National Knowledge Infrastructure, VIP Information Database, Wan Fang Database and reference lists of the eligible studies were searched up to July 2017 for relevant studies. METHODS: Randomized controlled trials that compared the combined effects of traditional manual acupuncture and rehabilitation therapy to rehabilitation therapy alone for shoulder hand syndrome after stroke were included...
September 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28901006/reproductive-aspects-of-the-atlantic-angel-shark-squatina-dumeril-in-the-southern-caribbean-sea
#14
A Tagliafico, S Rangel, M K Broadhurst
The maturity and reproduction of the Atlantic angel shark Squatina dumeril were assessed using 77 females (29·2-110·4 cm total length; LT ) and 269 males (58·7-108·2 cm LT ) harvested by artisanal gillnetters off Venezuela. The biased sex ratio implied segregation or sex-specific gear selectivity. Based on the development of the reproductive tract, 50% LT at sexual maturity (LT50 , mean ± s.e.) for females and males were estimated at 86·14 ± 0·64 and 81·55 ± 0·12 cm, respectively...
September 12, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28900367/measurement-of-hba1c-and-hba2-by-capillarys-2-flex-piercing-hba1c-programme-for-simultaneous-management-of-diabetes-and-screening-for-thalassemia
#15
Peifeng Ke, Jiawei Liu, Yan Chao, Xiaobin Wu, Yujuan Xiong, Li Lin, Zemin Wan, Xinzhong Wu, Jianhua Xu, Junhua Zhuang, Xianzhang Huang
INTRODUCTION: Thalassemia could interfere with some assays for haemoglobin A1c (HbA1c) measurement, therefore, it is useful to be able to screen for thalassemia while measuring HbA1c. We used Capillarys 2 Flex Piercing (Capillarys 2FP) HbA1c programme to simultaneously measure HbA1c and screen for thalassemia. MATERIALS AND METHODS: Samples from 498 normal controls and 175 thalassemia patients were analysed by Capillarys 2FP HbA1c programme (Sebia, France). For method comparison, HbA1c was quantified by Premier Hb9210 (Trinity Biotech, Ireland) in 98 thalassaemia patients samples...
October 1, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28895614/-negative-effects-of-psychotherapy-prevalence-and-correlates-in-a-clinical-sample
#16
Britta Abeling, Astrid Müller, Michael Stephan, Iris Pollmann, Martina de Zwaan
Introduction So far, the prevalence of negative effects of psychotherapy and their correlates have rarely been investigated in a systematic manner. The prevalence of negative effects varied between 3 studies with the Inventory for Assessing Negative Effects of Psychotherapy (INEP) with 20, 84, and 93.8% substantially. Thereby, the impact of bias effects remains unclear. In addition, reported correlates of the number of negative effects were examined and augmented with further correlates. Material and Methods For the study, a clinical sample of inpatients and day-patients (N=200) evaluated their previous psychotherapy retrospectively before their current admission with the Inventory for Assessing Negative Effects of Psychotherapy (INEP)...
September 11, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28894240/understanding-of-multi-level-resistive-switching-mechanism-in-geox-through-redox-reaction-in-h2o2-sarcosine-prostate-cancer-biomarker-detection
#17
Subhranu Samanta, Sheikh Ziaur Rahaman, Anisha Roy, Surajit Jana, Somsubhra Chakrabarti, Rajeswar Panja, Sourav Roy, Mrinmoy Dutta, Sreekanth Ginnaram, Amit Prakash, Siddheswar Maikap, Hsin-Ming Cheng, Ling-Na Tsai, Jian-Tai Qiu, Samit K Ray
Formation-free multi-level resistive switching characteristics by using 10 nm-thick polycrystalline GeOx film in a simple W/GeOx/W structure and understanding of switching mechanism through redox reaction in H2O2/sarcosine sensing (or changing Ge°/Ge(4+) oxidation states under external bias) have been reported for the first time. Oxidation states of Ge(0)/Ge(4+) are confirmed by both XPS and H2O2 sensing of GeOx membrane in electrolyte-insulator-semiconductor structure. Highly repeatable 1000 dc cycles and stable program/erase (P/E) endurance of >10(6) cycles at a small pulse width of 100 ns are achieved at a low operation current of 0...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28894193/sub-picosecond-temporal-resolution-of-anomalous-hall-currents-in-gaas
#18
Christian B Schmidt, Shekhar Priyadarshi, Mark Bieler
The anomalous Hall (AH) and spin Hall effects are important tools for the generation, control, and detection of spin and spin-polarized currents in solids and, thus, hold promises for future spintronic applications. Despite tremendous work on these effects, their ultrafast dynamic response is still not well explored. Here, we induce ultrafast AH currents in a magnetically-biased semiconductor by optical femtosecond excitation at room temperature. The currents' dynamics are studied by detecting the simultaneously emitted THz radiation...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28893677/accuracy-of-self-reported-heart-failure-the-atherosclerosis-risk-in-communities-aric-study
#19
Ricky Camplain, Anna Kucharska-Newton, Laura Loehr, Thomas C Keyserling, J Bradley Layton, Lisa Wruck, Aaron R Folsom, Alain G Bertoni, Gerardo Heiss
OBJECTIVE: To estimate agreement of self-reported heart failure (HF) with physician diagnosed HF and compare the prevalence of HF by method of ascertainment. STUDY DESIGN AND SETTING: ARIC cohort members (60-83 years of age) were asked annually whether a physician indicated they have HF. For those self-reporting HF, physicians were asked to confirm their patient's HF status. Physician diagnosed HF included surveillance of hospitalized HF, and hospitalized and outpatient HF identified in administrative claims databases...
September 8, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28893316/intraosseous-blood-samples-for-point-of-care-analysis-agreement-between-intraosseous-and-arterial-analyses
#20
Milla Jousi, Simo Saikko, Jouni Nurmi
BACKGROUND: Point-of-care (POC) testing is highly useful when treating critically ill patients. In case of difficult vascular access, the intraosseous (IO) route is commonly used, and blood is aspirated to confirm the correct position of the IO-needle. Thus, IO blood samples could be easily accessed for POC analyses in emergency situations. The aim of this study was to determine whether IO values agree sufficiently with arterial values to be used for clinical decision making. METHODS: Two samples of IO blood were drawn from 31 healthy volunteers and compared with arterial samples...
September 11, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
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