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https://www.readbyqxmd.com/read/29778717/first-time-mothers-expectations-of-the-unknown-territory-of-childbirth-uncertainties-coping-strategies-and-going-with-the-flow
#1
Sara E Borrelli, Denis Walsh, Helen Spiby
OBJECTIVE: To explore first-time mothers' expectations of labour and birth, coping strategies they adopt during pregnancy towards childbirth and coping strategies they expect to use during labour and birth. DESIGN: A qualitative Straussian grounded theory methodology was adopted, with data collected through semi-structured interviews in the third trimester of pregnancy. Ethical approval was gained. Data analysis included the processes of coding and conceptualising data, with constant comparison between data, literature and memos...
May 7, 2018: Midwifery
https://www.readbyqxmd.com/read/29777527/limiting-motor-skill-knowledge-via-incidental-training-protects-against-choking-under-pressure
#2
Taraz G Lee, Daniel E Acuña, Konrad P Kording, Scott T Grafton
The paradoxical harmful effects of motivation and incentives on skilled performance ("choking under pressure") are observed in a wide variety of motor tasks. Two theories of this phenomenon suggest that choking under pressure occurs due to maladaptive attention and top-down control, either through distraction away from the task or interference via an overreliance on controlled processing of a skilled task. A third theory, overmotivation (or overarousal), suggests that under pressure, "instinctive" or Pavlovian approach/withdrawal responses compete with the desired response...
May 18, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29757212/vibro-perception-of-optical-bio-inspired-fiber-skin
#3
Tao Li, Sheng Zhang, Guo-Wei Lu, Yuta Sunami
In this research, based on the principle of optical interferometry, the Mach-Zehnder and Optical Phase-locked Loop (OPLL) vibro-perception systems of bio-inspired fiber-skin are designed to mimic the tactile perception of human skin. The fiber-skin is made of the optical fiber embedded in the silicone elastomer. The optical fiber is an instinctive and alternative sensor for tactile perception with high sensitivity and reliability, also low cost and susceptibility to the magnetic interference. The silicone elastomer serves as a substrate with high flexibility and biocompatibility, and the optical fiber core serves as the vibro-perception sensor to detect physical motions like tapping and sliding...
May 12, 2018: Sensors
https://www.readbyqxmd.com/read/29751137/transferring-and-calibrating-safety-performance-functions-among-multiple-states
#4
Ahmed Farid, Mohamed Abdel-Aty, Jaeyoung Lee
Safety performance functions (SPFs), statistical regression models, by predicting traffic crash counts by crash type, severity and facility type, aid traffic engineers in the process of identifying high frequency crash locations. Developing SPFs requires the collection and processing of traffic, crash, road design and other characteristics' data. Jurisdictional agencies may choose not to develop their own SPFs and cut back on their resources by adopting SPFs provided by the national Highway Safety Manual (HSM)...
May 8, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29726567/aggregation-induced-phosphorescence-enhancement-of-mn-doped-zns-quantum-dots-the-role-of-dot-to-dot-distance
#5
Jinyi Zhang, Dandan Tang, Yadong Yao, Xiandeng Hou, Peng Wu
Assembled nanoparticles promote many applications in optics due to their instinct properties. The aggregation-induced phosphorescence enhancement (AIPE) of Mn-doped ZnS quantum dots (QDs) is widely used in biosensing, but the mechanism of such an enhancement is still unproven. This study explores the mechanism of the interesting finding of AIPE of Mn-doped ZnS QDs. To induce the aggregation of QDs, the method of electrostatic assembly was explored herein: negatively charged QDs were aggregated with protamine and positively charged QDs were aggregated with heparin...
May 4, 2018: Nanoscale
https://www.readbyqxmd.com/read/29719818/william-bradley-coley-md-and-the-phenomenon-of-spontaneous-regression
#6
REVIEW
Leonard F Vernon
The standard definition of spontaneous regression (SR) of cancer is as follows, "…when a malignant tumor partially or completely disappears without treatment or in the presence of therapy which is considered inadequate to exert a significant influence on neoplastic disease." SR is also known as Saint Peregrine tumor, the name taken from a young priest, Peregrine Laziosi (1260 [5]-1345, exact date is unknown), who had been diagnosed with a tumor of the tibia. The mass eventually grew so large that it broke through the skin and became severely infected...
2018: ImmunoTargets and Therapy
https://www.readbyqxmd.com/read/29684796/-they-told-me-all-mothers-have-worries-stillborn-mother-s-experiences-of-having-a-gut-instinct-that-something-is-wrong-in-pregnancy-findings-from-an-international-case-control-study
#7
Jane Warland, Alexander E P Heazell, Tomasina Stacey, Christin Coomarasamy, Jayne Budd, Edwin A Mitchell, Louise M O'Brien
OBJECTIVE: To describe and explore 'gut instinct' that something was wrong in women who identified that they experienced gut instinct during pregnancy. METHOD: A case-control study utilising an international web-based questionnaire. Stillborn cases (n = 146) and liveborn controls (n = 234) answered the gut instinct question within 30 days of the pregnancy ending. Of those, 84 cases and 27 controls also provided qualitative comment data. Descriptive statistics were used for the question, with a fixed option and summative content analysis was used to analyse the comment data...
April 11, 2018: Midwifery
https://www.readbyqxmd.com/read/29660383/dosage-form-modification-and-oral-drug-delivery-in-older-people
#8
Esther T L Lau, Kathryn J Steadman, Julie A Y Cichero, Lisa M Nissen
Many people cannot swallow whole tablets and capsules. The cause ranges from difficulties overriding the natural instinct to chew solids/foodstuff before swallowing, to a complex disorder of swallowing function affecting the ability to manage all food and fluid intake. Older people can experience swallowing difficulties because of co-morbidities, age-related physiological changes, and polypharmacy. To make medicines easier to swallow, many people will modify the medication dosage form e.g. split or crush tablets, and open capsules...
April 13, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29621146/effects-of-prolonged-silver-nanoparticle-exposure-on-the-contextual-cognition-and-behavior-of-mammals
#9
Anna Antsiferova, Marina Kopaeva, Pavel Kashkarov
Silver nanoparticles have been widely used in the lighting and food industries, in medicine, and in pharmaceutics as an antiseptic agent. Recent research demonstrates that, after prolonged oral administration, silver nanoparticles may cross the blood-brain barrier and accumulate in the brain in rather high amounts. In ex vivo experiments, it has also been shown that silver nanoparticles demonstrate neurotoxicity. The objective of this work was to answer the questions whether silver nanoparticles change cognitive and behavioral functions of mammals after prolonged administration if silver nanoparticles have accumulated in the brain...
April 5, 2018: Materials
https://www.readbyqxmd.com/read/29580906/post-traumatic-psychiatric-disorders-ptsd-is-not-the-only-diagnosis
#10
Yann Auxéméry
Traumatic events and their consequences are often hidden or minimised by patients for reasons linked to the post-traumatic stress disorder itself (inexpressibility, shame, depressive thoughts, fear of stigmatisation, etc.). Although post-traumatic stress disorder (PTSD) remains the most widely known disorder, chronic post-traumatic psychiatric disorders are many and varied. After a trauma, the practitioner has to check for the different clinical forms of post-traumatic psychological consequences: PTSD is not the only diagnosis...
May 2018: La Presse Médicale
https://www.readbyqxmd.com/read/29545208/cananga-odorata-essential-oil-reverses-the-anxiety-induced-by-1-3-chlorophenyl-piperazine-through-regulating-the-mapk-pathway-and-serotonin-system-in-mice
#11
Nan Zhang, Lei Zhang, Linyin Feng, Lei Yao
ETHNOPHARMACOLOGICAL RELEVANCE: Cananga odorata essential oil, known as ylang-ylang essential oil (YYO), was commonly used in the aromatherapy for relaxation and mood adjusting use. In our previous study, YYO played anxiolytic effects on the mice in several behavioral tests that based on the instinctive responses to novel environments. AIM OF THE STUDY: To investigate the effects and mechanisms of YYO reversing the anxiety induced by 5-HT2C receptor agonist 1-(3-chlorophenyl) piperazine (m-CPP)...
March 12, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29537845/fostering-the-basic-instinct-of-boron-in-boron-beryllium-interactions
#12
M Merced Montero-Campillo, Ibon Alkorta, José Elguero
A set of complexes L2 HB···BeX2 (L = CNH, CO, CS, N2 , NH3 , NCCH3 , PH3 , PF3 , PMe3 , OH2 ; X = H, F) containing a boron-beryllium bond is described at the M06-2X/6-311+G(3df,2pd)//M062-2X/6-31+G(d) level of theory. In this quite unusual bond, boron acts as a Lewis base and beryllium as a Lewis acid, reaching binding energies up to -283.3 kJ/mol ((H2 O)2 HB···BeF2 ). The stabilization of these complexes is possible thanks to the σ-donor role of the L ligands in the L2 HB···BeX2 structures and the powerful acceptor nature of beryllium...
March 29, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29535004/distribution-of-pituitary-adenylate-cyclase-activating-polypeptide-2-in-zebrafish-brain
#13
Tomoya Nakamachi, Eri Kamata, Ayano Tanigawa, Norifumi Konno, Seiji Shioda, Kouhei Matsuda
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a multipotent neuropeptide with an amino acid sequence that is well conserved among vertebrates. In teleosts, including zebrafish, the PACAP gene (adcyap1) has been duplicated to yield adcyap1a (coding PACAP1) and adcyap1b (coding PACAP2). This study aims to determine the distribution of these PACAPs and their mRNAs in zebrafish. We generated a zebrafish PACAP2-specific antibody. Using real-time PCR, we observed that adcyap1b mRNA was primarily localized in the brain, with the highest level in the telencephalon, followed by the diencephalon...
May 2018: Peptides
https://www.readbyqxmd.com/read/29534617/celebrating-the-health-literacy-skills-of-parents-a-photovoice-study
#14
Emee Vida Estacio, Lavinia Nathan, Joanne Protheroe
Parents play a vital role in promoting children's health. The parental health literacy skills are important since the decisions they make can have an impact on other family members' health and well-being. Using an assets-based approach, this project aimed to explore the skills parents use to communicate health messages with their children and how they manage their family's health. Six adult parents of children aged 0-16 years old took part in this photovoice study. The thematic analysis suggests that tapping into the creativity of parents through the gamification of health messages and encouraging children's independence are effective ways to promote healthy behaviors...
March 1, 2018: Journal of Health Psychology
https://www.readbyqxmd.com/read/29517984/single-center-experience-of-a-new-endoscopic-clip-in-managing-nonvariceal-upper-gastrointestinal-bleeding
#15
Praneet Wander, Daniel Castaneda, Lionel D'Souza, Simi Singh, Sam Serouya, Ana I Velazquez, Rifat Mamun, Rebecca Voaklander, Petros Benias, David L Carr-Locke
BACKGROUND: To assess the safety and efficacy of the Instinct clip in the acute endoscopic treatment of upper gastrointestinal bleeding (UGIB). MATERIALS AND METHODS: This is the first large series reporting this clip in achieving hemostasis. A retrospective descriptive chart review was performed on patients presenting with recent overt GI bleeding treated with endoclip therapy at Mount Sinai Beth Israel Medical Center between May 2013 and January 2016. Results are expressed in absolute numbers, percentages, and trends...
April 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29508091/current-treatment-options-headache-related-to-menopause-diagnosis-and-management
#16
REVIEW
Clinton G Lauritsen, Abigail L Chua, Stephanie J Nahas
PURPOSE OF REVIEW: Menopause is a life-changing event in numerous ways. Many women with migraine hold hope that the transition to the climacteric state will coincide with a cessation or improvement of migraine. This assumption is based mainly on common lay perceptions as well as assertions from many in the healthcare community. Unfortunately, evidence suggests this is far from the rule. Many women turn to a general practitioner or a headache specialist for prognosis and management. A natural instinct is to manipulate the offending agent, but in some cases, this approach backfires, or the concern for adverse events outweighs the desire for a therapeutic trial, and other strategies must be pursued...
March 6, 2018: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29502952/stress-accelerates-defensive-responses-to-looming-in-mice-and-involves-a-locus-coeruleus-superior-colliculus-projection
#17
Lei Li, Xiaolong Feng, Zheng Zhou, Huiqi Zhang, Qianqian Shi, Zhuogui Lei, Peilei Shen, Qingning Yang, Binghao Zhao, Shuran Chen, Lin Li, Yulin Zhang, Pengjie Wen, Zhonghua Lu, Xiang Li, Fuqiang Xu, Liping Wang
Defensive responses to threatening stimuli are crucial to the survival of species. While expression of these responses is considered to be instinctive and unconditional, their magnitude may be affected by environmental and internal factors. The neural circuits underlying this modulation are still largely unknown. In mice, looming-evoked defensive responses are mediated by the superior colliculus (SC), a subcortical sensorimotor integration center. We found that repeated stress caused an anxiety-like state in mice and accelerated defensive responses to looming...
March 19, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29501731/a-limit-in-the-dynamic-increase-in-the-accuracy-of-group-migration
#18
Vladimir N Binhi
Many migratory animals regularly travel thousands of kilometers, exactly finding their seasonal destinations. The nature of this ability is still not fully understood. The aggregation of animals in groups and their socially coordinated movement is considered a way to eliminate navigational errors. Orientation accuracy of a group may be significantly higher as the errors caused by a variety of casual factors are averaged due to social interactions. This idea, called the "many wrongs principle," has been confirmed both in behavioral experiments and numerical simulations...
April 2018: Bio Systems
https://www.readbyqxmd.com/read/29489747/hierarchical-neural-architecture-underlying-thirst-regulation
#19
Vineet Augustine, Sertan Kutal Gokce, Sangjun Lee, Bo Wang, Thomas J Davidson, Frank Reimann, Fiona Gribble, Karl Deisseroth, Carlos Lois, Yuki Oka
Neural circuits for appetites are regulated by both homeostatic perturbations and ingestive behaviour. However, the circuit organization that integrates these internal and external stimuli is unclear. Here we show in mice that excitatory neural populations in the lamina terminalis form a hierarchical circuit architecture to regulate thirst. Among them, nitric oxide synthase-expressing neurons in the median preoptic nucleus (MnPO) are essential for the integration of signals from the thirst-driving neurons of the subfornical organ (SFO)...
March 8, 2018: Nature
https://www.readbyqxmd.com/read/29488892/-the-concept-of-the-limit-%C3%AE-metapsychological-approach-of-the-freudian-theory
#20
Ν Tsipa, F Houssier
This article is referring to the study of the "limit" according to a metapsychological point of view. The main definition of this concept concerns its double possibility to relate and to separate the internal from the external reality. It is about a review of the post-freudian work: the theoretical contribution of the authors P. Federn, D. Anzieu and D.W. Winnicott is viewed through the conceptualisation of the "limit". Also, the study of A. Green, who is the author who proposed not only the concept of the "limit" but also the concept of the "double limit"...
October 2017: Psychiatrikē, Psychiatriki
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