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coronary bifurcation intervention

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https://www.readbyqxmd.com/read/29124548/development-of-an-experimental-and-digital-cardiovascular-arterial-model-for-transient-hemodynamic-and-postural-change-studies-a-preliminary-framework-analysis
#1
Rodward L Hewlin, John P Kizito
The ultimate goal of the present work is to aid in the development of tools to assist in the treatment of cardiovascular disease. Gaining an understanding of hemodynamic parameters for medical implants allow clinicians to have some patient-specific proposals for intervention planning. In the present work an experimental and digital computational fluid dynamics (CFD) arterial model consisting of a number of major arteries (aorta, carotid bifurcation, cranial, femoral, jejunal, and subclavian arteries) were fabricated to study: (1) the effects of local hemodynamics (flow parameters) on global hemodynamics (2) the effects of transition from bedrest to upright position (postural change) on hemodynamics, and (3) diffusion of dye (medical drug diffusion simulation) in the arterial system via experimental and numerical techniques...
November 9, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29116819/double-guide-double-wrist-5f-left-coronary-artery-transradial-percutaneous-coronary-intervention-and-the-x-kiss-technique
#2
Dangoisse Vincent, Schroëder Erwin, Claude Hanet, Antoine Guédès, Pancholy Samir
Percutaneous coronary intervention for bifurcated anatomy, particularly at the proximal left coronary artery site, requires guide catheters (GC) of at least 6 french and preferably larger in diameter. We describe a new trans-radial approach more suitable for small artery size: the simultaneous use of both radial arteries for double cannulation of the LMCA with 5F GC: each GC will target either the LM/LAD or the LM/CX artery (or LM-LAD/LM-LAD-1st diagonal branch) stenoses. The technique successfully was applied to 5 cases...
November 8, 2017: Acute Cardiac Care
https://www.readbyqxmd.com/read/29108400/early-experience-and-favorable-clinical-outcomes-of-everolimus-eluting-bioresorbable-scaffolds-for-coronary-artery-disease-in-korea
#3
Osung Kwon, Jung-Min Ahn, Do-Yoon Kang, Se Hun Kang, Pil Hyung Lee, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Duk-Woo Park, Seung-Jung Park
Background/Aims: Compared with metallic drug-eluting stents (DES), bioresorbable vascular scaffolds (BVS) may further improve long-term outcomes of percutaneous coronary intervention (PCI) in patients with coronary artery disease. We report our early experience with BVS in Korea. Methods: We evaluated 105 consecutive patients with BVS implanted at Asan Medical Center, Korea between October 21, 2015 and June 3, 2016. Angiographic results, and in-hospital and 6-month clinical outcomes were assessed...
November 7, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29102580/usefulness-of-the-jailed-balloon-technique%C3%A2-in-percutaneous-intervention-for%C3%A2-severe-coronary-perforation-involving%C3%A2-left-main-bifurcation
#4
Kensuke Takagi, Koichi Furui, Itsuro Morishima, Tsuboi Hideyuki
No abstract text is available yet for this article.
October 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29096915/double-kissing-crush-versus-provisional%C3%A2-stenting-for-left-main-distal%C3%A2-bifurcation-lesions-dkcrush-v-randomized-trial
#5
Shao-Liang Chen, Jue-Jie Zhang, Yaling Han, Jing Kan, Lianglong Chen, Chunguang Qiu, Tiemin Jiang, Ling Tao, Hesong Zeng, Li Li, Yong Xia, Chuanyu Gao, Teguh Santoso, Chootopol Paiboon, Yan Wang, Tak W Kwan, Fei Ye, Nailiang Tian, Zhizhong Liu, Song Lin, Chengzhi Lu, Shangyu Wen, Lang Hong, Qi Zhang, Imad Sheiban, Yawei Xu, Lefeng Wang, Tanveer S Rab, Zhanquan Li, Guanchang Cheng, Lianqun Cui, Martin B Leon, Gregg W Stone
BACKGROUND: Provisional stenting (PS) is the most common technique used to treat distal left main (LM) bifurcation lesions in patients with unprotected LM coronary artery disease undergoing percutaneous coronary intervention. The double kissing (DK) crush planned 2-stent technique has been shown to improve clinical outcomes in non-LM bifurcations compared with PS, and in LM bifurcations compared with culotte stenting, but has never been compared with PS in LM bifurcation lesions. OBJECTIVES: The authors sought to determine whether a planned DK crush 2-stent technique is superior to PS for patients with true distal LM bifurcation lesions...
October 20, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29074039/percutaneous-coronary-intervention-of-bifurcation-lesions-and-platelet-reactivity
#6
Björn Redfors, Philippe Généreux, Bernhard Witzenbichler, Ajay J Kirtane, Akiko Maehara, Giora Weisz, Mahesh V Madhavan, Thomas McAndrew, Roxana Mehran, Gregg W Stone
BACKGROUND: Although bifurcation percutaneous coronary intervention (PCI) is associated with lower procedural success rates and higher risk of complications, there are little data regarding outcomes after successful bifurcation PCI with contemporary stents and techniques. Whether residual platelet reactivity (PR) affects outcomes differently after bifurcation versus non-bifurcation PCI is also unknown. We studied the association between bifurcation PCI, PR, and clinical outcomes among patients undergoing successful PCI with drug-eluting stents...
October 7, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29073947/lesion-complexity-and-outcomes-of-extended-dual-antiplatelet-therapy-after-percutaneous-coronary-intervention
#7
RANDOMIZED CONTROLLED TRIAL
Robert W Yeh, Dean J Kereiakes, P Gabriel Steg, Donald E Cutlip, Kevin J Croce, Joseph M Massaro, Laura Mauri
BACKGROUND: Subjects undergoing coronary stenting with complex lesion anatomy may experience different risks and benefits with prolonged dual antiplatelet therapy. OBJECTIVES: The authors assessed the effect of 30 months versus 12 months of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) based on the presence or absence of anatomically-complex target lesions. METHODS: In the DAPT Study, combined myocardial infarction (MI) or stent thrombosis and moderate/severe bleeding were assessed in enrolled (n = 25,416) and randomized (n = 11,554) subjects...
October 31, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29061550/percutaneous-coronary-intervention-for-the-left-main-stem-and-other-bifurcation-lesions-the-12-th-consensus-document-from-the-european-bifurcation-club
#8
Jens Flensted Lassen, Francesco Burzotta, Adrian P Banning, Thierry Lefèvre, Olivier Darremont, David Hildick-Smith, Alaide Chieffo, Manuel Pan, Niels Ramsing Holm, Yves Louvard, Goran Stankovic
The European Bifurcation Club (EBC) was initiated in 2004, to support a continuously overview of the field of coronary artery bifurcation interventions and aims to facilitate a scientific discussion and an exchange of ideas on management of bifurcation disease. EBC hosts an annual, two days compact meeting, dedicated to bifurcations, which brings together physicians, pathologists, engineers, biologists, physicists, mathematicians, epidemiologists and statisticians for detailed discussions. Every meeting is finalized with a consensus statement that reflects the unique opportunity of combining the opinion of interventional cardiologists with the opinion of a large variety of other scientists on bifurcation management...
October 24, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29052106/effect-of-low-density-lipoprotein-cholesterol-on-the-geometry-of-coronary-bifurcation-lesions-and-clinical-outcomes-of-coronary-interventions-in-the-j-reverse-registry
#9
Yoshinobu Murasato, Yoshihisa Kinoshita, Masahiro Yamawaki, Toshiro Shinke, Yoshihiro Takeda, Kenichi Fujii, Shin-Ichiro Yamada, Yoshihisa Shimada, Takehiro Yamashita, Kazuhiko Yumoto
We investigated the effect of low-density lipoprotein cholesterol (LDL-C) on the geometry of coronary bifurcation lesions. A total of 300 non-left main bifurcation lesions in 298 patients from J-REVERSE registry were classified according to statin treatment status at admission (NT, non-treated; ST, statin-treated) and were further subdivided based on LDL-C levels with a cutoff of 100 mg/dL (NT-high, n = 76 lesions; NT-low, n = 46; ST-high, n = 99 and ST-low, n = 79). In addition, a group with strict control of LDL-C (< 70 mg/dL) was defined (ST-SC; n = 19)...
October 19, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/29038413/percutaneous-coronary-intervention-for-coronary-bifurcation-lesions
#10
William Finch, Michael S Lee
Percutaneous coronary intervention (PCI) of lesions at coronary bifurcations poses a technical challenge. Short-term complications, including periprocedural myocardial infarction, and long-term complications such as in-stent restenosis and stent thrombosis, are higher in patients with bifurcation lesions. Techniques for PCI of bifurcation lesions include stenting of the main branch alone, and the use of two or more stents to cover the main and side branches. Two- or three-stent techniques include T-stenting, crush, culotte, simultaneous kissing stents, V-stenting, and Y-stenting...
2017: Reviews in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28992999/provisional-versus-elective-two-stent-strategy-for-unprotected-true-left-main-bifurcation-lesions-insights-from-a-fails-2-sub-study
#11
Hiroyoshi Kawamoto, Alaide Chieffo, Fabrizio D'Ascenzo, Richard J Jabbour, Toru Naganuma, Enrico Cerrato, Fabrizio Ugo, Marco Pavani, Ferdinando Varbella, Giacomo Boccuzzi, Mauro Pennone, Roberto Garbo, Federico Conrotto, Giuseppe Biondi-Zoccai, Maurizio D'Amico, Claudio Moretti, Javier Escaned, Fiorenzo Gaita, Sunao Nakamura, Antonio Colombo
BACKGROUND: This study sought to investigate the optimal percutaneous coronary intervention (PCI) strategy for true unprotected left main coronary artery (ULMCA) bifurcations. METHODS: The FAILS-2 was a retrospective multi-center study including patients with ULMCA disease treated with second-generation drug-eluting stents. Of these, we compared clinical outcomes of a provisional strategy (PS; n=216) versus an elective two-stent strategy (E2S; n=161) for true ULMCA bifurcations...
October 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28940552/clinical-and-angiographic-outcomes-of-axial-stent-deformations-in-unrestricted-real-world-patient-population
#12
Mahmoud Sabbah, Kazushige Kadota, Shunsuke Kubo, Yusuke Hyodo, Suguru Otsuru, Daiji Hasegawa, Takeshi Tada, Seiji Habara, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto
BACKGROUND: Prior reports have suggested that the design of the Promus Element stent is prone to longitudinal stent deformation (LSD). However, little is known about the clinical and angiographic outcomes of Promus Element stent axial deformations when implanted in unrestricted coronary lesions. METHOD AND RESULTS: Two independent reviewers retrospectively evaluated the procedure steps of 961 Promus Element stent (833 de novo lesions in 494 consecutive patients) implanted in unrestricted coronary lesions, between February 2012 and March 2013, and compared the prevalence, predictors, and the mid-term clinical and angiographic outcomes between lesions with and without stent deformation...
September 20, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28926354/neointimal-coverage-of-jailed-side-branches-in-coronary-bifurcation-lesions-an-optical-coherence-tomography-analysis
#13
Teruyoshi Kume, Ryotaro Yamada, Koyama Terumasa, Tomoko Tamada, Koichiro Imai, Kenzo Fukuhara, Yutaka Goryo, Ai Kawamura, Okamoto Hiroshi, Yoji Neishi, Shiro Uemura
OBJECTIVES: The jailed strut at the side-branch (SB) orifice may be a cause of delayed neointimal coverage and SB flow disturbance after single stenting to bifurcation. The aim of this study was to characterize the exact relationship between the jailed strut pattern at the SB orifice immediately after stent implantation and neointimal coverage of the jailed SB orifice in the chronic phase. PATIENTS AND METHODS: A total of 29 bifurcation (left anterior descending coronary artery and diagonal branch) lesions treated by optical coherence tomography-guide single-stent implantation and followed at 18 months after a percutaneous coronary intervention were included in this study...
September 18, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28844030/state-of-the-art-balloon-catheter-technologies-drug-coated-balloon
#14
Fernando Alfonso, Bruno Scheller
Four decades after its introduction into clinical practice, coronary balloon angioplasty is still used during most coronary interventions. Conventional balloon angioplasty is frequently used to predilate complex or severe lesions and remains of major value to optimise the results of stent implantation. Plain balloon angioplasty is still used alone in some anatomic scenarios where stent implantation is not desirable (very small vessels or diffuse lesions, large resistant thrombus burden, side branches of bifurcations)...
August 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28844026/state-of-the-art-coronary-angiography
#15
Carlos Collet, Maik J Grundeken, Taku Asano, Yoshinobu Onuma, William Wijns, Patrick W Serruys
In the early days of coronary angiography, the precise quantification of luminal narrowing was challenging. The introduction of balloon angioplasty (percutaneous transluminal coronary angioplasty [PTCA]) by Andreas Grüntzig in 1977 was perhaps the greatest incentive to the development of quantitative coronary angiography (QCA). QCA has played a crucial role in evaluating interventional techniques and assessing the results of new technologies. With the advent of drug-eluting stents (DES), QCA metrics such as late lumen loss and diameter stenosis (restenosis) proved to be instrumental in assessing new technologies...
August 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28835831/three-dimensional-optical-frequency-domain-imaging-of-a-true-bifurcation-lesion-after-stent-implantation-using-the-jailed-semi-inflated-balloon-technique
#16
Yohei Numasawa, Hiromu Hase, Hiroyuki Yamazaki, Ryota Tabei, Toshiki Kuno, Masaki Kodaira, Tetsuya Saito
OBJECTIVE: Percutaneous coronary intervention for coronary bifurcation lesion is very challenging, especially for true bifurcation lesions. Although the jailed semi-inflated balloon technique is one of the established methods for treatment of coronary bifurcation lesions, little is known regarding the configuration of the side branch orifice after stent implantation using this technique. METHODS: We report a 73-year-old male patient with angina pectoris who was successfully treated with percutaneous coronary stent implantation for a true bifurcation lesion of the right coronary artery with an obtuse angle using the jailed semi-inflated balloon technique...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28830751/treatment-of-de-novo-coronary-artery-bifurcation-lesions-with-drug-coated-balloons-a-reappraisal-according-to-the-available-scientific-data
#17
REVIEW
Marco Zuin, Gianluca Rigatelli
The treatment of coronary artery bifurcation often represents a challenge for interventional cardiologist. Although several stenting techniques are available for the treatment of de novo coronary bifurcation lesions, over the last years, different studies have proposed and analysed the use of drug-coated balloon (DCB) in the treatment of coronary artery bifurcation lesions as an alternative treatment. To date, even considering those studies which have analysed a combined strategy (DCB+stenting) or a DCB-only approach, the evidences are scant and the results debatable...
July 11, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28829743/intracoronary-electrocardiogram-to-guide-percutaneous-interventions-in-coronary-bifurcations-a-proof-of-concept-the-fiesta-ffr-vs-icecgsta-study
#18
Dobrin Vassilev, Liubomir Dosev, Carlos Collet, Kiril Karamfiloff, Jivka Stoikova, Ralica Pancheva, Monika Shumkova, Galina Zlatancheva, Vladimir Naunov, Gianluca Rigatelli, Ghassan S Kassab, Robert J Gil, Patrick W Serruys
AIMS: The aim of this study was to determine the accuracy of the intracoronary electrocardiogram (icECG) to detect ischemia during bifurcation lesions percutaneous coronary intervention (PCI) with fractional flow reserve (FFR) as a reference. METHODS AND RESULTS: Patients with significant bifurcation lesions defined as FFR≤0.80 were included. FFR and icECG were performed in the main vessel (MV) and side branch (SB) before and after provisional stenting. icECG was recorded with a uninsulated proximal wire end connected to a unipolar lead...
August 22, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28797113/clinical-outcomes-of-biodegradable-polymer-biolimus-eluting-biomatrix-stents-versus-durable-polymer-everolimus-eluting-xience-stents
#19
MULTICENTER STUDY
Da Hyon Lee, Taek Kyu Park, Young Bin Song, Woo Jung Chun, Rak Kyeong Choi, Jin-Ok Jeong, Eul Soon Im, Sang Wook Kim, Joo Myung Lee, Jeong Hoon Yang, Joo-Yong Hahn, Seung-Hyuk Choi, Jin-Ho Choi, Sang Hoon Lee, Hyeon-Cheol Gwon
There are limited data about clinical outcomes of biodegradable polymer biolimus-eluting BioMatrix stents (BP-BES) and durable polymer everolimus-eluting Xience stents (DP-EES) in real world practice. We sought to compare the clinical outcomes of BP-BES and DP-EES in real world cohorts of patients undergoing percutaneous coronary intervention. A prospective multicenter registry enrolled 999 patients treated with BP-BES and 1,000 patients treated with DP-EES. The primary outcome was target lesion failure, defined as a composite of cardiac death, target vessel-related myocardial infarction, or target lesion revascularization...
2017: PloS One
https://www.readbyqxmd.com/read/28794001/randomized-comparison-of-ridaforolimus-and-zotarolimus-eluting-coronary-stents-in-patients-with-coronary-artery-disease-primary-results-from-the-bionics-trial-bionir-ridaforolimus-eluting-coronary-stent-system-in-coronary-stenosis
#20
RANDOMIZED CONTROLLED TRIAL
David E Kandzari, Pieter C Smits, Michael P Love, Ori Ben-Yehuda, Shmuel Banai, Simon D Robinson, Michael Jonas, Ran Kornowski, Rodrigo Bagur, Andres Iniguez, Haim Danenberg, Robert Feldman, Rajiv Jauhar, Harish Chandna, Manish Parikh, Gidon Y Perlman, Mercedes Balcells, Peter Markham, Melek Ozgu Ozan, Philippe Genereux, Elazer R Edelman, Martin B Leon, Gregg W Stone
BACKGROUND: The safety and efficacy of a novel cobalt alloy-based coronary stent with a durable elastomeric polymer eluting the antiproliferative agent ridaforolimus for treatment of patients with coronary artery disease is undetermined. METHODS: A prospective, international 1:1 randomized trial was conducted to evaluate in a noninferiority design the relative safety and efficacy of ridaforolimus-eluting stents (RESs) and slow-release zotarolimus-eluting stents among 1919 patients undergoing percutaneous coronary intervention at 76 centers...
October 3, 2017: Circulation
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