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https://www.readbyqxmd.com/read/29135784/fitness-fatness-physical-activity-and-autonomic-function-in-midlife
#1
Antti M Kiviniemi, Nelli Perkiömäki, Juha Auvinen, Maisa Niemelä, Tuija Tammelin, Katri Puukka, Aimo Ruokonen, Sirkka Keinänen-Kiukaanniemi, Mikko P Tulppo, Marjo-Riitta Järvelin, Timo Jämsä, Heikki V Huikuri, Raija Korpelainen
PURPOSE: Although low cardiorespiratory fitness (CRF), physical inactivity, and obesity are associated with impaired autonomic function, they are also extensively interrelated. The present study aimed to assess the extent to which they contribute to autonomic function independently of each other. METHODS: At the age of 46 yr, 1383 men and 1761 women without cardiorespiratory diseases and diabetes underwent assessments of vagally mediated heart rate (HR) variability (root mean square of successive differences in R-R interval (rMMSD)), peak HR during a submaximal step test (CRF), and 60-s HR recovery (HRR)...
December 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29135601/sex-differences-in-cardiac-baroreflex-sensitivity-following-isometric-handgrip-exercise
#2
André L Teixeira, Raphael Ritti-Dias, Diego Antonino, Martim Bottaro, Philip J Millar, Lauro C Vianna
PURPOSE: To investigate potential sex-related differences on spontaneous cardiac baroreflex sensitivity (cBRS) following acute isometric handgrip (IHG) exercise. METHODS: Twenty men (23±3 years) and 20 women (24±4 years) randomly performed four sets of 2-min IHG exercise (two sets for each limb) at 30% maximum voluntary contraction (MVC - experimental) or 3% MVC (sham). Beat-to-beat heart rate (HR) and arterial blood pressure (BP) were monitored using finger photoplethysmography before and 10-, 20-, and 30-min following IHG...
November 13, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29134169/age-and-tumor-volume-predict-growth-of-carotid-and-vagal-body-paragangliomas
#3
Berdine L Heesterman, Lisa M H de Pont, Berit M Verbist, Andel G L van der Mey, Eleonora P M Corssmit, Frederik J Hes, Peter Paul G van Benthem, Jeroen C Jansen
Objective  Treatment for head and neck paragangliomas (HNGPL) can be more harmful than the disease. After diagnosis, an initial period of surveillance is often indicated, and surgery or radiotherapy is reserved for progressive disease. With the aim to optimize this "wait and scan" strategy, we studied growth and possible predictors. Design  A retrospective cohort study was conducted. Setting  This study was conducted at a tertiary referral center for patients with HNGPL. Methods  Tumor volume was estimated for 184 SDHD -related carotid and vagal body paragangliomas using sequential magnetic resonance imaging...
December 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29131129/effect-of-diazepam-on-24-hour-blood-pressure-and-heart-rate-in-healthy-young-volunteers
#4
Alfredo Costa, Daniele Bosone, Annalisa Zoppi, Angela D Apos Angelo, Natascia Ghiotto, Elena Guaschino, Matteo Cotta Ramusino, Roberto Fogari
AIM: To assess the effects of evening chronic administration of diazepam on 24-h blood pressure (BP) and heart rate (HR) in healthy young adults. METHODS: This randomized double blind, cross-over study evaluated the effects of diazepam 5 mg or placebo, both ingested in the evening, on 24-h ambulatory BP and HR in healthy subjects aged 21-30. RESULTS: A total of 30 subjects were included in the analysis. At the end of 4-week diazepam intake, an increase in 24-h HR mean values was found (+5...
October 31, 2017: Pharmacology
https://www.readbyqxmd.com/read/29130483/contributions-of-infant-vagal-regulation-at-1-month-to-subsequent-joint-attention-abilities
#5
Vera Mateus, Sara Cruz, Fernando Ferreira-Santos, Ana Osório, Adriana Sampaio, Carla Martins
Since birth, humans develop an ability to regulate their inner states and behaviors, when facing demanding situations, in order to restore calmness and engage with other persons and the surrounding environment. The present study analyzed whether 1-month infant vagal regulation to auditory stimuli was associated with later joint attention abilities-responding to and initiating joint attention-in interaction with their mothers. Twenty-three infants were assessed and measures of respiratory sinus arrhythmia-RSA (baseline and vagal tone change during auditory stimulation) were used as index of vagal regulation...
November 12, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/29130228/-valuation-and-prospect-of-function-preserving-gastrectomy
#6
Shuchang Wang, Site Yu, Jia Xu, Gang Zhao
Preserving gastric function and improving quality of life (QOL) is the tendency of surgery for early gastric cancer. Function preserving gastrectomy (FPG) is applied to modify the extent of surgery and to achieve better quality of life at the premise of radical resection. Pylorus-preserving gastrectomy is the most favorable approach of FPG with oncological safety, which can improve nutritional status and QOL via preserving pylorus and vagal nerve. Proximal gastrectomy is widely accepted as FPG for early upper 1/3 gastric cancer...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29128975/transcutaneous-vagus-nerve-stimulation-tvns-modulates-flow-experience
#7
Lorenza S Colzato, Gina Wolters, Corinna Peifer
Flow has been defined as a pleasant psychological state that people experience when completely absorbed in an activity. Previous correlative evidence showed that the vagal tone (as indexed by heart rate variability) is a reliable marker of flow. So far, it has not yet been demonstrated that the vagus nerve plays a causal role in flow. To explore this we used transcutaneous vagus nerve stimulation (tVNS), a novel non-invasive brain stimulation technique that increases activation of the locus coeruleus (LC) and norepinephrine release...
November 11, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29128294/behavioral-depression-is-associated-with-increased-vagally-mediated-heart-rate-variability-in-adult-female-cynomolgus-monkeys-macaca-fascicularis
#8
Marc N Jarczok, Julian Koenig, Carol A Shively, Julian F Thayer
INTRODUCTION: Depressive symptoms (DS) in humans are associated with decreased resting state vagal activity, but sex seems to moderate this association. Recently, in human females DS have been associated with greater or similar cardiac vagal activity compared to men in both, clinical and non-clinical samples. A previously validated animal model of behavioral depression was used in the present study to investigate the association of DS and cardiac vagal activity in non-human primates. METHODS: The root mean square of successive differences between adjacent heart beats (RMSSD) was used as an indicator of vagally-mediated heart rate variability in 24h heart rate recordings collected via telemetry in 42 adult female cynomolgus monkeys (Macaca fascicularis)...
November 8, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29127856/acute-and-long-term-effects-of-fingolimod-on-heart-rhythm-and-heart-rate-variability-in-patients-with-multiple-sclerosis
#9
Ruken Özge Akbulak, Sina C Rosenkranz, Benjamin N Schaeffer, Hans O Pinnschmidt, Stephan Willems, Christoph Heesen, Boris A Hoffmann
BACKGROUND: Fingolimod can lead to increased risk of cardiac events such as bradycardia or atrioventricular (AV) block. OBJECTIVE: Evaluate acute and long-term effects of fingolimod on heart rhythm (HR), heart rate variability (HRV) and development of AV-blocks. METHODS: In 64 patients with relapsing-remitting multiple sclerosis Holter ECG monitoring (HEM) and HRV analysis were performed 24h before, six h during and 72h after initiation of fingolimod...
November 2, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29127549/preservation-of-the-celiac-branch-of-the-vagal-nerve-for-pylorus-preserving-gastrectomy-is-it-meaningful
#10
Haruna Furukawa, Manabu Ohashi, Michitaka Honda, Koshi Kumagai, Souya Nunobe, Takeshi Sano, Naoki Hiki
BACKGROUND: Preserving the hepatic and pyloric branches of the vagal nerve in laparoscopic pylorus-preserving gastrectomy (LPPG) is considered necessary to maintain the function of the pyloric cuff. However, the clinical benefits of preservation of the celiac branch of the vagal nerve (CBVN) remain unclear. METHODS: Of 391 patients who underwent LPPG for early gastric cancer, 116 patients in whom the CBVN was preserved (CBP group) and 58 patients in whom it was not preserved (non-CBP group) were selected through the propensity score-matching method...
November 10, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29127233/vascular-endothelial-function-masks-increased-sympathetic-vasopressor-activity-in-rats-with-metabolic-syndrome
#11
Sylvain Battault, Cindy Meziat, Alessandro R Nascimento, Laura Braud, Sandrine Gayrard, Christian Legros, Frederic De Nardi, Jocelyne Drai, Olivier Cazorla, Jérôme Thireau, Gregory Meyer, Cyril Reboul
OBJECTIVE: Sympathetic hyperactivation, a common feature of obesity and metabolic syndrome, is a key trigger of hypertension. However, some obese subjects with autonomic unbalance present a dissociation between sympathetic activity mediated vasoconstriction and increased blood pressure. Here, we aimed to determine in a rat model of metabolic syndrome, whether the endothelium eNOS-NO pathway contribute to counteract the vasopressor effect of the sympathetic system. METHODS: Rats were fed a high fat and high sucrose diet for 15 weeks (HFS)...
November 10, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29121716/risk-prediction-in-post-infarction-patients-with-moderately-reduced-left-ventricular-ejection-fraction-by-combined-assessment-of-the-sympathetic-and-vagal-cardiac-autonomic-nervous-system
#12
W Hamm, L Stülpnagel, N Vdovin, G Schmidt, K D Rizas, A Bauer
AIM: Most deaths after myocardial infarction (MI) occur in patients with normal or moderately reduced left ventricular ejection fraction (LVEF >35%). Periodic repolarization dynamics (PRD) and deceleration capacity (DC) are novel ECG-based markers related to sympathetic and vagal cardiac autonomic nervous system activity. Here, we test the combination of PRD and DC to predict risk in post-infarction patients with LVEF >35%. METHODS AND RESULTS: We included 823 survivors of acute MI with LVEF >35%, aged ≤80years and in sinus rhythm...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29120949/cardiac-vagal-tone-as-a-reliable-index-of-pain-chronicity-and-severity
#13
Dmitry M Davydov
No abstract text is available yet for this article.
December 2017: Pain
https://www.readbyqxmd.com/read/29117509/heart-rate-variability-mediates-the-link-between-rumination-and-depressive-symptoms-a-longitudinal-study
#14
Luca Carnevali, Julian F Thayer, Jos F Brosschot, Cristina Ottaviani
Ruminative thinking about negative feelings has been prospectively associated with increases in depressive symptoms and heightened risk for new onsets of major depression. One putative pathophysiological mechanism underlying this link might be represented by autonomic nervous system dysfunction. The objective of this longitudinal study was to evaluate the interplay between rumination, autonomic function (as revealed by heart rate variability (HRV) analysis), and depressive symptoms in healthy young subjects, over a three-year period...
November 5, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29113812/differential-associations-of-lower-cardiac-vagal-tone-with-insulin-resistance-and-insulin-secretion-in-recently-diagnosed-type-1-and-type-2-diabetes
#15
Dan Ziegler, Alexander Strom, Gidon Bönhof, Sonja Püttgen, Kálmán Bódis, Volker Burkart, Karsten Müssig, Julia Szendroedi, Daniel F Markgraf, Michael Roden
OBJECTIVE: It is unclear to which extent altered insulin sensitivity/secretion contribute to the development of diabetic cardiovascular autonomic neuropathy (CAN) characterized by diminished heart rate variability (HRV). We hypothesised that lower HRV is differentially associated with measures of insulin resistance and insulin secretion in recent-onset type 1 and type 2 diabetes. MATERIALS/METHODS: This cross-sectional study included participants from the German Diabetes Study with type 1 (n=275) or type 2 diabetes (n=450) with known diabetes duration ≤1 year and glucose-tolerant controls (n=81)...
November 4, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29110883/linear-and-nonlinear-parameters-of-heart-rate-variability-in-ischemic-stroke-patients
#16
V Constantinescu, D Matei, V Costache, D Cuciureanu, C Arsenescu-Georgescu
INTRODUCTION: Cardiovascular system presents cortical modulation. Post-stroke outcome can be highly influenced by autonomic nervous system disruption. Heart rate variability (HRV) analysis is a simple non-invasive method to assess sympatho-vagal balance. OBJECTIVES: The purpose of this study was to investigate cardiac autonomic activity in ischemic stroke patients and to asses HRV nonlinear parameters beside linear ones. METHODS: We analyzed HRV parameters in 15 right and 15 left middle cerebral artery ischemic stroke patients, in rest condition and during challenge (standing and deep breathing)...
October 11, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29110082/continuous-monitoring-of-the-recurrent-laryngeal-nerve
#17
Aitor De la Quintana Basarrate, Arantza Iglesias Martínez, Iciar Salutregui, Leire Agirre Etxabe, Ainhoa Arana González, Izaskun Yurrebaso Santamaría
OBJECTIVE: The objective of this study was to assess the safety and utility of continuous intraoperative neuromonitoring for the prevention of recurrent laryngeal nerve injury during thyroidectomy. METHODS: A prospective cohort study was conducted in consecutive patients undergoing thyroidectomy. Variations in amplitude and distal latency of the electromyogram (EMG) were assessed. In the case of suspicious events, restorative manoeuvers were performed to attempt to recover the potentials...
November 6, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29108781/retinoic-acid-temporally-orchestrates-colonization-of-the-gut-by-vagal-neural-crest-cells
#18
Rosa A Uribe, Stephanie S Hong, Marianne E Bronner
The enteric nervous system arises from neural crest cells that migrate as chains into and along the primitive gut, subsequently differentiating into enteric neurons and glia. Little is known about the mechanisms governing neural crest migration en route to and along the gut in vivo. Here, we report that Retinoic Acid (RA) temporally controls zebrafish enteric neural crest cell chain migration. In vivo imaging reveals that RA loss severely compromises the integrity and migration of the chain of neural crest cells during the window of time window when they are moving along the foregut...
November 3, 2017: Developmental Biology
https://www.readbyqxmd.com/read/29107952/hereditary-angioedema-assessing-the-hypothesis-for-underlying-autonomic-dysfunction
#19
Maddalena A Wu, Francesco Casella, Francesca Perego, Chiara Suffritti, Nada Afifi Afifi, Eleonora Tobaldini, Andrea Zanichelli, Chiara Cogliati, Nicola Montano, Marco Cicardi
BACKGROUND: Attacks of Hereditary Angioedema due to C1-inhibitor deficiency (C1-INH-HAE)are often triggered by stressful events/hormonal changes. OBJECTIVE: Our study evaluates the relationship between autonomic nervous system (ANS) and contact/complement system activation. METHODS: Twenty-three HAE patients (6 males, mean age 47.5±11.4 years) during remission and 24 healthy controls (8 males, mean age 45.3±10.6 years) were studied. ECG, beat-by-beat blood pressure, respiratory activity were continuously recorded during rest (10') and 75-degrees-head-up tilt (10')...
2017: PloS One
https://www.readbyqxmd.com/read/29107740/autonomic-function-testing-compliance-and-consequences
#20
Thorsten Kamlarczyk Rasmussen, John Hansen, Phillip A Low, Paola Sandroni, Wolfgang Singer, Troels Staehelin Jensen, Astrid Juhl Terkelsen
BACKGROUND: The deep breathing test (DB) and Valsalva maneuver (VM) are used to detect autonomic dysfunction. The VM induces sympathetically mediated changes in blood pressure (phase II late, phase IV, and recovery time) and both tests induce vagally mediated heart rate changes. There is limited information on effects of key variables, compliance with testing and the effects of non-compliance This study has twin goals of evaluating compliance with standard instructions and the effects of changes in key variables...
October 18, 2017: Autonomic Neuroscience: Basic & Clinical
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