keyword
MENU ▼
Read by QxMD icon Read
search

vagal

keyword
https://www.readbyqxmd.com/read/28337838/the-selective-metabotropic-glutamate-receptor-5-antagonist-mavoglurant-afq056-reduces-the-incidence-of-reflux-episodes-in-dogs-and-patients-with-moderate-to-severe-gastroesophageal-reflux-disease
#1
M-L Rouzade-Dominguez, N Pezous, O J David, R Tutuian, S Bruley des Varannes, J Tack, P Malfertheiner, H-D Allescher, M Ufer, A Rühl
BACKGROUND: Transient lower esophageal sphincter relaxations (TLESRs) induced by gastric distension are modulated by the metabotropic glutamate receptor 5 (mGluR5) that influences the vagal reflex loop. We therefore aimed to examine the effects of the selective mGluR5 antagonist mavoglurant (AFQ056) on the number of TLESRs in dogs and reflux episodes in patients with gastroesophageal reflux disease (GERD). METHODS: In a dog model, the number of meal-induced TLESRs was determined after intravenous (0...
March 23, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28337432/the-current-and-future-role-of-heart-rate-variability-for-assessing-and-training-compassion
#2
James N Kirby, James R Doty, Nicola Petrocchi, Paul Gilbert
The evolution of mammalian caregiving involving hormones, such as oxytocin, vasopressin, and the myelinated vagal nerve as part of the ventral parasympathetic system, enables humans to connect, co-regulate each other's emotions and create prosociality. Compassion-based interventions draw upon a number of specific exercises and strategies to stimulate these physiological processes and create conditions of "interpersonal safeness," thereby helping people engage with, alleviate, and prevent suffering. Hence, compassion-based approaches are connected with our evolved caring motivation and attachment and our general affiliative systems that help regulate distress...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28334441/flexible-parasympathetic-responses-to-sadness-facilitate-spontaneous-affect-regulation
#3
Jonathan P Stange, Jessica L Hamilton, David M Fresco, Lauren B Alloy
The ability of the parasympathetic nervous system to flexibly adapt to changes in environmental context is thought to serve as a physiological indicator of self-regulatory capacity, and deficits in parasympathetic flexibility appear to characterize affective disorders such as depression. However, whether parasympathetic flexibility (vagal withdrawal to emotional or environmental challenges such as sadness, and vagal augmentation during recovery from sadness) could facilitate the effectiveness of adaptive affect regulation strategies is not known...
March 23, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28328743/acetylcholine-atropine-interactions-paradoxical-effects-on-atrial-fibrillation-inducibility
#4
Yu Liu, Benjamin J Scherlag, Youqi Fan, Wenfang Xia, He Huang, Sunny S Po
Atropine (ATr) is well known as a cholinergic antagonist, however, at low concentrations ATr could paradoxically accentuate the parasympathetic actions of acetylcholine (ACh). In 22 pentobarbital anesthetized dogs, via a left and right thoracotomy, a leak proof barrier was attached to isolate the atrial appendages (AAs) from the rest of the atria. In Group 1(Ach+ATr+Ach), ACh, 100 mM, was placed on the AA followed by the application of ATr, 2mg/cc. The average AFdur was 17±7 minutes. After ATr was applied to the AA and ACh again tested, the AFdur was markedly attenuated (2±2 minutes, p<0...
March 21, 2017: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/28328721/heart-rate-decreases-during-head-out-of-water-immersion-and-with-lower-body-weight-support-a-measure-of-vagal-reserve
#5
Louis F Salciccioli, Haroon Kamran, Yang Liu, John G Kral, Jason M Lazar
No abstract text is available yet for this article.
April 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28323625/the-effects-of-stretching-training-on-cardiac-autonomic-function-in-obese-postmenopausal-women
#6
Alexei Wong, Marcos Sanchez-Gonzalez, Roy Kalfon, Stacey Alvarez-Alvarado, Arturo Figueroa
Context • Menopause and obesity are associated with autonomic dysfunction. Unconventional exercise modalities that include an important flexibility component seem to improve cardiac autonomic function by lowering sympathetic tone and increasing vagal modulation of the heart rate (HR). Yet clear evidence of the effects of stretching training (ST) on cardiac autonomic modulation is limited. Objective • The present study intended to examine the effects of ST on HR variability (HRV) and flexibility in obese postmenopausal women...
March 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28322837/role-of-prostanoid-ep3-1-receptors-in-mechanisms-of-emesis-and-defaecation-in-ferrets
#7
Kelvin K W Kan, Man K Wai, Robert L Jones, John A Rudd
Prostanoid EP receptor agonists are used for a number of clinical indications but may be associated with gastric disturbance. In the present studies we used the ferret and sulprostone (30µg/kg, i.p.) to investigate the role of EP3/1 receptors in mechanisms of emesis and defaecation. The emetic response was antagonized significantly by (+)-(2S,3S)-3-(2-methoxybenzylamino)-2-phenlypiperidine hydrochloride (CP-99,994; 10mg/kg, i.p.; P<0.05), but not by metoclopramide (0.3 and 3mg/kg), ondansetron (0.1 and 1mg/kg), or scopolamine (3mg/kg); promethazine (3mg/kg) potentiated emesis by approximately 82% (P<0...
March 16, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28321772/paragangliomas-of-the-head-and-neck-an-overview-from-diagnosis-to-genetics
#8
Michelle D Williams
Paragangliomas (PGL) develop from the parasympathetic system in the head and neck (HN) and arise primarily in four distinct areas: Carotid body, vagal, middle ear, and larynx. Globally, the diagnosis and morphologic features are the same regardless of anatomic site, however the incidence, frequency of genetic alterations/syndromes and differential diagnosis vary. It is now recognized that nearly 40% of all HN PGLs are hereditary, including a significant subset without a known family history. Now pathologists are central to the evaluation for diagnosis and further management of patients with HNPGLs...
March 20, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28321127/ancient-evolutionary-origin-of-vertebrate-enteric-neurons-from-trunk-derived-neural-crest
#9
Stephen A Green, Benjamin R Uy, Marianne E Bronner
The enteric nervous system of jawed vertebrates arises primarily from vagal neural crest cells that migrate to the foregut and subsequently colonize and innervate the entire gastrointestinal tract. Here we examine development of the enteric nervous system in the basal jawless vertebrate the sea lamprey (Petromyzon marinus) to gain insight into its evolutionary origin. Surprisingly, we find no evidence for the existence of a vagally derived enteric neural crest population in the lamprey. Rather, labelling with the lipophilic dye DiI shows that late-migrating cells, originating from the trunk neural tube and associated with nerve fibres, differentiate into neurons within the gut wall and typhlosole...
March 20, 2017: Nature
https://www.readbyqxmd.com/read/28320626/relationship-between-laryngeal-electromyography-and-video-laryngostroboscopy-in-vocal-fold-paralysis
#10
Joel A Maamary, Ian Cole, Paul Darveniza, Cecilia Pemberton, Helen Mary Brake, Stephen Tisch
OBJECTIVES/HYPOTHESIS: The objective of this study was to better define the relationship of laryngeal electromyography and video laryngostroboscopy in the diagnosis of vocal fold paralysis. STUDY DESIGN: Retrospective diagnostic cohort study with cross-sectional data analysis METHODS: Data were obtained from 57 patients with unilateral vocal fold paralysis who attended a large tertiary voice referral center. Electromyographic findings were classified according to recurrent laryngeal nerve, superior laryngeal nerve, and high vagal/combined lesions...
March 17, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28320117/use-of-social-media-to-assess-the-effectiveness-of-vagal-nerve-stimulation-in-dravet-syndrome-a-caregiver-s-perspective
#11
Rushna Ali, Mona Elsayed, Manpreet Kaur, Ellen Air, Naznin Mahmood, Jules Constantinou, Jason Schwalb
BACKGROUND: Dravet syndrome (DS) is a rare genetic epilepsy syndrome which is particularly pharmacoresistant. Vagus nerve stimulation (VNS) is commonly used in the treatment of DS as an adjunct to medical therapy. A meaningful assessment of post-surgical outcomes with VNS is difficult given the rarity of the condition. OBJECTIVE: In a novel approach, we used social media to contact patients with DS to gather data on post-surgical seizure reduction and overall satisfaction with VNS...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28317837/inhibitory-responses-mediated-by-vagal-nerve-stimulation-are-diminished-in-stomachs-of-mice-with-reduced-intramuscular-interstitial-cells-of-cajal
#12
Elizabeth A H Beckett, Kenton M Sanders, Sean M Ward
Intramuscular interstitial cells of Cajal (ICC-IM) are closely associated with enteric motor nerve terminals and electrically coupled to smooth muscle cells within the gastric musculature. Previous studies investigating the role of ICC-IM in motor neurotransmission have used indiscriminate electric field stimulation of neural elements within the gastric wall. To determine the role of ICC-IM in transduction of vagally-mediated motor input to gastric muscles electrical and mechanical responses to selective electrical vagal stimulation (EVS) were recorded from gastric fundus and antral regions of wild type and W/W(V) mice, which lack most ICC-IM...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28298947/glomus-vagale-tumour-can-it-be-diagnosed-only-on-sonography
#13
Shuchi Bhatt, Pooja Verma, Neha Meena, Anupama Tandon, Nadeem Tanveer, Divya Bansal
Vagal paragangliomas are rare benign tumors accounting for only 3% of head and neck paragangliomas and arise from vagal ganglions, predominately the nodose ganglion in the carotid sheath. Imaging plays an important role in their diagnosis, differentiation from more common lesions presenting in the carotid space, and management. MRI is the method of choice for investigation when paragangliomas are clinically suspected. The typical salt-and-pepper appearance in T1-weighted images is well known but not specific to paragangliomas...
March 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/28298797/cervical-vagal-schwannoma-anesthetic-concerns
#14
Suman Saini, Nikki Sabharwal, Nidhi Agrawal, Bhupender Singh
Schwannomas arising from cervical vagus nerve is an extremely rare benign neoplasm. The majority of patients present with insidiously growing lateral neck mass without neurological deficit. We report a case of symptomatic cervical vagal nerve schwannoma in a 32-year-old female. Complete surgical resection is the treatment of choice. However, anesthetic management of these tumors can be challenging. We describe here the complications experienced during the management of the patient.
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298036/efficacy-and-safety-of-corpus-callosotomy-after-vagal-nerve-stimulation-in-patients-with-drug-resistant-epilepsy
#15
Jennifer Hong, Atman Desai, Vijay M Thadani, David W Roberts
OBJECTIVE Vagal nerve stimulation (VNS) and corpus callosotomy (CC) have both been shown to be of benefit in the treatment of medically refractory epilepsy. Recent case series have reviewed the efficacy of VNS in patients who have undergone CC, with encouraging results. There are few data, however, on the use of CC following VNS therapy. METHODS The records of all patients at the authors' center who underwent CC following VNS between 1998 and 2015 were reviewed. Patient baseline characteristics, operative details, and postoperative outcomes were analyzed...
March 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28296184/long-term-administration-of-pyridostigmine-attenuates-pressure-overload-induced-cardiac-hypertrophy-by-inhibiting-calcineurin-signalling
#16
Yi Lu, Ming Zhao, Jin-Jun Liu, Xi He, Xiao-Jiang Yu, Long-Zhu Liu, Lei Sun, Li-Na Chen, Wei-Jin Zang
Cardiac hypertrophy is associated with autonomic imbalance, characterized by enhanced sympathetic activity and withdrawal of parasympathetic control. Increased parasympathetic function improves ventricular performance. However, whether pyridostigmine, a reversible acetylcholinesterase inhibitor, can offset cardiac hypertrophy induced by pressure overload remains unclear. Hence, this study aimed to determine whether pyridostigmine can ameliorate pressure overload-induced cardiac hypertrophy and identify the underlying mechanisms...
March 10, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28295842/police-work-stressors-and-cardiac-vagal-control
#17
Michael E Andrew, John M Violanti, Ja K Gu, Desta Fekedulegn, Shengqiao Li, Tara A Hartley, Luenda E Charles, Anna Mnatsakanova, Diane B Miller, Cecil M Burchfiel
OBJECTIVES: This study examines relationships between the frequency and intensity of police work stressors and cardiac vagal control, estimated using the high frequency component of heart rate variability (HRV). METHODS: This is a cross-sectional study of 360 officers from the Buffalo New York Police Department. Police stress was measured using the Spielberger police stress survey, which includes exposure indices created as the product of the self-evaluation of how stressful certain events were and the self-reported frequency with which they occurred...
March 14, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28295425/prophylactic-atropine-administration-prevents-vasovagal-response-induced-by-cryoballoon-ablation-in-patients-with-atrial-fibrillation
#18
Liping Sun, Jian-Zeng Dong, Xin DU, Rong Bai, Songnan Li, Mohamed Salim, Chang-Sheng Ma
BACKGROUND: Cryoballoon ablation of pulmonary vein (PV) ostia often induces a vagal response.This prospective study was designed to assess the effectiveness of prophylactic intravenous administration of atropine on hemodynamic impairment induced by cryoballoon ablation in patients with atrial fibrillation. METHODS: Twenty-five patients with paroxysmal atrial fibrillation undergoing cryoballoon ablation were prospectively enrolled and assigned to one of two groups...
March 11, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28295242/an-update-on-non-pharmacological-neuromodulation-for-the-acute-and-preventive-treatment-of-migraine
#19
Francesca Puledda, Peter J Goadsby
OBJECTIVE: To review current neuromodulation treatments available for migraine therapy, both in the acute and preventive setting. METHODS: The published literature was reviewed for studies reporting the effects of different neuromodulation strategies in migraine with and without aura. The use of non-invasive: single pulse transcranial magnetic stimulation, non-invasive vagal nerve stimulation, supraorbital nerve stimulation, and transcranial direct current stimulation, as well as invasive methods such as occipital nerve stimulation and sphenopalatine ganglion stimulation, are assessed...
March 13, 2017: Headache
https://www.readbyqxmd.com/read/28294385/potential-excitatory-role-of-nitric-oxide-on-2-deoxy-d-glucose-induced-gastric-motility-in-rats
#20
A M Sevgili, Z D Balkanci, A Erdem
Previous studies have shown that 2-deoxy-d-glucose (2-DG) increases gastric motility via the vagus nerve, but the underlying mechanism remains elusive. Since nitric oxide (NO) is involved in gastric motility, a possible interplay between 2-DG and NO can be suggested. In the present study, Wistar rats (250-350 g) of both sexes were intravenously injected with 2-DG (200 mg·kg(-1) ), and the effects of the intravenous injection of the nitric oxide synthase (NOS) inhibitors; nitro-l-arginine methyl ester (l-NAME, 10 mg·kg(-1) ) and N(ω) -nitro-l-arginine (l-NNA, 10 mg·kg(-1) ) were investigated...
March 13, 2017: Clinical and Experimental Pharmacology & Physiology
keyword
keyword
81137
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"