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https://www.readbyqxmd.com/read/29244993/cervical-cancer-in-the-greater-accra-and-ashanti-regions-of-ghana
#1
Yvonne Nartey, Philip C Hill, Kwabena Amo-Antwi, Kofi M Nyarko, Joel Yarney, Brian Cox
Purpose Cervical cancer is a common cancer among women worldwide. An estimated 528,000 new cases and 266,000 deaths occurred in 2012. More than 85% of invasive cervical cancer cases occur in low- and middle-income countries. Cervical cancer ranks as the most common cancer among women in Ghana. We conducted a retrospective study to assess the descriptive epidemiology of cervical cancer in Ghana. We describe cervical cancer incidence and mortality rates for the regions served by two large hospitals in Ghana. Patients and Methods Information for women diagnosed with invasive cervical cancer between 2010 and 2013 was collected from the Komfo Anokye and Korle Bu Teaching Hospitals through review of medical, computer, and pathology records at the oncology units and the obstetrics and gynecology departments...
December 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29244227/surveillance-for-hepatobiliary-cancers-in-patients-with-primary-sclerosing-cholangitis
#2
Ahmad Hassan Ali, James H Tabibian, Navine Naser-Ghodsi, Ryan J Lennon, Thomas DeLeon, Mitesh J Borad, Moira Hilscher, Marina G Silveira, Elizabeth J Carey, Keith D Lindor
BACKGROUND AND AIMS: Primary sclerosing cholangitis (PSC) is a risk factor for cholangiocarcinoma (CCA) and gallbladder carcinoma (GBCa). Surveillance for GBCa is recommended, but the clinical utility of surveillance for other hepatobiliary cancers (HBCa) in PSC, namely CCA and hepatocellular carcinoma (HCC), is unclear. We aimed to determine whether surveillance is associated with better survival after diagnosis of HBCa in patients with PSC. METHODS: Medical records of PSC patients seen at Mayo Clinic Rochester from 1995-2015 were reviewed...
December 15, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29243838/evaluation-of-umbilical-vein-blood-volume-flow-in-preeclampsia-by-angle-independent-3d-sonography
#3
Stephen Z Pinter, Oliver D Kripfgans, Marjorie C Treadwell, Anna W Kneitel, J Brian Fowlkes, Jonathan M Rubin
OBJECTIVES: To investigate the association between umbilical vein blood volume flow and the condition of preeclampsia in an at-risk maternal patient cohort. Umbilical vein volume flow was quantified by a 3-dimensional (3D) sonographic technique that overcomes several limitations of standard sonographic flow measurement methods. METHODS: A total of 35 patients, each with a singleton pregnancy, were recruited to provide 5 patients with preeclampsia, derived as a subset from a 26-patient at-risk group, and 9 patients with normal pregnancies...
December 15, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29243168/the-views-of-patients-with-metastatic-prostate-cancer-towards-physical-activity-a-qualitative-exploration
#4
G Sheill, E Guinan, L O Neill, D Hevey, J Hussey
PURPOSE: Patients with metastatic cancer can experience debilitating symptoms, which may influence attitudes towards and engagement in physical activity. This study aimed to examine the attitudes of patients living with metastatic prostate cancer towards physical activity. MATERIALS AND METHODS: Semi-structured interviews were completed with male patients living with metastatic prostate cancer. Interviews included eight questions related to patients' attitudes towards physical activity...
December 14, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29243028/perspectives-from-the-patient-and-the-healthcare-professional-in-multiple-sclerosis-social-media-and-patient-education
#5
Daniel Kantor, Jeremy R Bright, Jeri Burtchell
A diagnosis of multiple sclerosis (MS) is life-altering. Because the course of MS is heterogeneous, patients may face uncertainty in terms of long-term physical and cognitive challenges, potential loss of employment, and the risk of social isolation. Patients often turn to the Internet and social media for information about MS and its management, and to seek out fellow patients and support groups. Here, we examine the use of social media and the Internet among patients with MS, considering its impact on patient education...
December 14, 2017: Neurology and Therapy
https://www.readbyqxmd.com/read/29241649/the-structure-of-the-mental-lexicon-what-primary-progressive-aphasias-reveal
#6
Clara Sanches, Alexandre Routier, Olivier Colliot, Marc Teichmann
Like recursive syntax, a structured mental lexicon is specific to the human species but its internal organization remains unclear. It is thought to contain information about the semantic, syntactic (e.g., gender) and formal (orthographic/phonological) features of a word. Previous studies suggested that these three components might be separated at the behavioral level and that they might be implemented by temporal cortices. However, the available investigations are based on case reports or small-cohort studies with patients demonstrating post-stroke aphasia, and they did not contrast the three lexical components in a directly comparable way...
December 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29241120/a-study-on-the-association-of-mood-disorders-and-gluten-related-diseases
#7
Brunetta Porcelli, Valeria Verdino, Fabio Ferretti, Nicola Bizzaro, Lucia Terzuoli, Francesca Cinci, Letizia Bossini, Andrea Fagiolini
Our study aimed to evaluate the presence of antibodies related to gluten intolerance in patients with mood disorders. A total of 60 patients with a diagnosis of bipolar disorder or depressive disorder were recruited. Fourty-eight subjects randomly selected among unrelated family members were included as controls. Celiac disease-associated antibodies were assayed both in the patients and controls. Mean values of IgA/IgG anti-gliadin antibodies, IgA/IgG anti-deamidated gliadin peptide antibodies and IgA anti-transglutaminase (tTG) antibodies were not different between patients and controls...
December 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29238492/the-prevalence-of-visual-disorders-in-iranian-students-a-meta-analysis-study-and-systematic-review
#8
Kambiz Keshavarz, Parvin Angha, Fatemeh Sayehmiri, Kourosh Sayemiri, Masood Yasemi
Background: Visual defects have dramatic effects on health, self-esteem, and educational function of students, and delayed diagnosis will cause complications, like academic failure and psychologic disorders. Objective: The present study aimed to investigate the prevalence of ocular disorders in Iranian students in a systematic review. Methods: We searched databases, including PubMed, SID, Magiran, Google Scholar, and Iranmedex using the following keywords in Persian and English: disorders, vision, amblyopia, refractive errors, astigmatism, student, and Iran with all the possible combinations, important, chief, and sensitive words...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29238390/modulatory-effect-of-association-of-brain-stimulation-by-light-and-binaural-beats-in-specific-brain-waves
#9
Mauricio Rocha Calomeni, Vernon Furtado da Silva, Bruna Brandão Velasques, Olavo Guimarães Feijó, Juliana Marques Bittencourt, Alair Pedro Ribeiro de Souza E Silva
Introduction: One of the positive effects of brain stimulation is interhemispheric modulation as shown in some scientific studies. This study examined if a type of noninvasive stimulation using binaural beats with led-lights and sound would show different modulatory effects upon Alfa and SMR brain waves of elderlies and children with some disease types. Subjects: The sample included 75 individuals of both genders, being, randomly, divided in 6 groups. Groups were named elderly without dementia diagnosis (EWD), n=15, 76±8 years, elderly diagnosed with Parkinson's disease (EDP), n=15, 72±7 years, elderly diagnosed with Alzheimer's disease (EDA), n=15, 81±6 years...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29238103/clinical-features-of-patients-with-infective-endocarditis-presenting-to-the-emergency-department-a-retrospective-case-series
#10
Naruhiro Jingushi, Mitsunaga Iwata, Teruhiko Terasawa
Infective endocarditis (IE) is an uncommon clinical problem with diverse, nonspecific presentations. Therefore, information on the clinical features of IE patients presenting to emergency departments (EDs) is scarce. To descriptively analyze the pertinent data, we performed a retrospective chart review. We reviewed 15 consecutive IE patients admitted directly from ED in a university hospital in Japan between 2013 and 2015. We compared their clinical features with those of 14 IE patients admitted during the same period without ED presentations...
November 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29237913/the-clinical-significance-of-secreted-protein-acidic-and-rich-in-cysteine-expression-in-breast-cancer-tissue-and-its-association-with-prognosis
#11
Wei Guo, Mingliang Zhang, Yong Chen, Suyang Guo
OBJECTIVE: The aim of this study was to evaluate the secreted protein acidic and rich in cysteine (SPARC) expression in breast cancer tissue and its association with patients' clinical pathology characteristics and prognosis. MATERIALS AND METHODS: Eight-eight cases with confirmed diagnosis of breast cancer who received operation from January 2010 to February 2016 were included in this study. The SPARC expression in cancer tissue was examined by immunohistochemical method...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29237654/investigating-the-effect-of-sociodemographic-factors-on-30-day-hospital-readmission-among-medical-patients-in-toronto-canada-a-prospective-cohort-study
#12
Robert W Smith, Kerry Kuluski, Andrew P Costa, Samir K Sinha, Richard H Glazier, Alan Forster, Lianne Jeffs
OBJECTIVE: To examine the influence of patient-level sociodemographic factors on the incidence of hospital readmission within 30 days among medical patients in a large Canadian metropolitan city. DESIGN: Prospective cohort study. SETTING AND PARTICIPANTS: Patients admitted to the General Internal Medicine service of an urban teaching hospital in Toronto, Canada participated in a survey of sociodemographic information. Patients were not surveyed if deemed medically unstable, receiving care in medical/surgical step-down beds or were isolated for infection control...
December 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29237444/development-and-assessment-of-an-active-strategy-for-the-implementation-of-a-collaborative-care-approach-for-depression-in-primary-care-the-indi%C3%A2-i-project
#13
Enric Aragonès, Diego Palao, Germán López-Cortacans, Antonia Caballero, Narcís Cardoner, Pilar Casaus, Myriam Cavero, José Antonio Monreal, Víctor Pérez-Sola, Miquel Cirera, Maite Loren, Eva Bellerino, Catarina Tomé-Pires, Laura Palacios
BACKGROUND: Primary care is the principal clinical setting for the management of depression. However, significant shortcomings have been detected in its diagnosis and clinical management, as well as in patient outcomes. We developed the INDI collaborative care model to improve the management of depression in primary care. This intervention has been favorably evaluated in terms of clinical efficacy and cost-effectiveness in a clinical trial. Our aim is to bring this intervention from the scientific context into clinical practice...
December 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29237442/factors-impacting-the-illness-trajectory-of-post-infectious-fatigue-syndrome-a-qualitative-study-of-adults-experiences
#14
Eva Stormorken, Leonard A Jason, Marit Kirkevold
BACKGROUND: Post-infectious fatigue syndrome (PIFS), also known as post-viral fatigue syndrome, is a complex condition resulting in physical, cognitive, emotional, neurological, vocational and/or role performance disabilities in varying degrees that changes over time. The needs for health care resources are high, and costly, as is the economic burden on the affected individuals. Many factors may impact the trajectory, and frequently PIFS develops into a chronic condition. Health professionals lack understanding and knowledge, which results in delayed diagnosis, lack of recognition, appropriate treatment, support and practical help...
December 13, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29237405/prevalence-and-characteristics-of-hereditary-non-polyposis-colorectal-cancer-hnpcc-syndrome-in-immigrant-asian-colorectal-cancer-patients
#15
Jasmine Lee, Yin-Yi Xiao, Yan Yu Sun, Jasminka Balderacchi, Bradley Clark, Jatin Desani, Vivek Kumar, Angela Saverimuthu, Khin Than Win, Yiwu Huang, Yiqing Xu
BACKGROUND: The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2, and EPCAM. A non-hereditary, acquired process of hypermethylation of the MLH1 promoter can also lead to silencing of MLH1 protein expression. Diagnosis of HNPCC in patients with colorectal and other related cancers is important in the clinical treatment and surveillance of related cancers...
December 13, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29237355/cross-cultural-adaptation-of-the-victorian-institute-of-sports-assessment-achilles-visa-a-questionnaire-for-spanish-athletes
#16
Sergio Hernández-Sánchez, Emilio José Poveda-Pagán, Yasser Alakhdar, Maria Dolores Hidalgo-Montesinos, César Fernández-de-Las-Peñas, José L Arias-Buría
Study Design Clinical measurement study. Background Achilles tendinopathy is a prevalent sport-related injury. The Victorian Institute of Sports Assessment-Achilles (VISA-A) questionnaire is a widely-used patient-reported outcome to assess the severity of symptoms for this injury. Objective To adapt the VISA-A questionnaire into Spanish and to assess its psychometric properties. Methods Cross-cultural adaptation was conducted according to recommended guidelines. The Spanish VISA-A (VISA-A-Sp) questionnaire was administered to 210 subjects: 70 healthy students, 70 active at risk subjects (participating in running and jumping) and 70 patients with Achilles tendinopathy diagnosis...
December 13, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29237139/outcomes-of-laparoscopic-colectomy-in-younger-and-older-patients-an-analysis-of-nationwide-readmission-database
#17
Hemalkumar B Mehta, Byron D Hughes, Eric Sieloff, Sneha O Sura, Yong Shan, Deepak Adhikari, Anthony Senagore
BACKGROUND: Prior studies report safety and effectiveness of laparoscopic colectomy in older patients. The study aimed to examine the impact of laparoscopic colectomy on 30-day readmissions, discharge destination, hospital length of stay, and cost in younger (19-65 years) and older adults (>65 years). MATERIALS AND METHODS: We used the nationwide readmission database from 2013 to study adults undergoing elective colectomy. The outcomes were 30-day readmissions, discharge destination for the index hospitalization (routine, skilled nursing facility [SNF]/intermediate care facility [ICF], home healthcare), length of stay, and cost...
December 13, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29236748/the-diagnostic-use-of-choroidal-thickness-analysis-and-its-correlation-with-visual-field-indices-in-glaucoma-using-spectral-domain-optical-coherence-tomography
#18
Zhongjing Lin, Shouyue Huang, Ping Huang, Lei Guo, Xi Shen, Yisheng Zhong
PURPOSE: To evaluate the quantitative characteristics of choroidal thickness in primary open-angle glaucoma (POAG), normal tension glaucoma (NTG) and in normal eyes using spectral-domain optical coherence tomography (SD-OCT). To evaluate the diagnostic ability of choroidal thickness in glaucoma and to determine the correlation between choroidal thickness and visual field parameters in glaucoma. METHODS: A total of 116 subjects including 40 POAG, 30 NTG and 46 healthy subjects were enrolled in this study...
2017: PloS One
https://www.readbyqxmd.com/read/29235617/-predictors-of-seizure-related-injuries-in-adult-patients-with-epilepsy-in-colombia-a-case-control-study
#19
J P Orozco-Hernandez, J F Quintero-Moreno, C Duque-Salazar, A Gil-Restrepo, J William-Martinez, A Lizcano-Meneses, H Carmona-Villada
AIM: To identify predictors of seizure related injuries in adult patients with epilepsy in Colombia. SUBJECTS AND METHODS: Case-control study. Patients with a diagnosis of epilepsy aged 16 years and older who attended the Neurocentro epilepsy center between 2013-2016 and were attended by a specialist in epilepsy were included. Patients with seizure related injuries were defined as the case. The control group was conformed by those without seizure related injuries...
December 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/29235490/fibroblasts-play-a-potential-role-in-bone-destruction-via-osteopontin-related-caldesmon-expression-and-polymerization-in-human-non-functioning-pituitary-adenomas
#20
Li-Yang Zhang, Xiao-Lu Ge, Zheng Li, Yong-Jian Tang, Yuan-Yuan Xiong, Xue-Jun Li, Jin-Fang Liu, Si-Yi Wanggou, Chun-Tao Li, Kui Yang, Xin Chen, Zhong-Liang Hu, Yun-Sheng Liu, Zhi-Xiong Liu
Non-functioning pituitary adenomas (NFPAs) are the most frequent pituitary tumors. The elucidation of the mechanisms of aggressive NFPAs in bone destruction is required in order to guide the clinical diagnosis and treatment of NFPAs. In the present study, we investigated the differential proteomics of fibroblasts isolated from clinical specimens of NFPAs with or without bone destruction. Proteomic analysis revealed a group of molecules associated with cytoskeleton organization, including caldesmon, were differentially expressed between fibroblasts isolated from bone destruction NFPAs (BD-NFPAs) and fibroblasts isolated from non-bone destruction NFPAs (NBD-NFPAs)...
December 13, 2017: Scientific Reports
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