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https://www.readbyqxmd.com/read/29457583/financial-incentives-to-reduce-hospital-acquired-infections-under-alternative-payment-arrangements
#1
Catherine Crawford Cohen, Jianfang Liu, Bevin Cohen, Elaine L Larson, Sherry Glied
OBJECTIVE The financial incentives for hospitals to improve care may be weaker if higher insurer payments for adverse conditions offset a portion of hospital costs. The purpose of this study was to simulate incentives for reducing hospital-acquired infections under various payment configurations by Medicare, Medicaid, and private payers. DESIGN Matched case-control study. SETTING A large, urban hospital system with 1 community hospital and 2 tertiary-care hospitals. PATIENTS All patients discharged in 2013 and 2014...
February 19, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29457522/a-high-prevalence-of-tmd-is-related-to-somatic-awareness-and-pain-intensity-among-healthy-dental-students
#2
Anna Lövgren, Catharina Österlund, Aurelija Ilgunas, Ewa Lampa, Fredrik Hellström
OBJECTIVE: Dental students have been identified as a group with high risks of developing both temporomandibular disorders (TMD) and psychosocial conditions. Our primary aim was to evaluate the cross-sectional prevalence of TMD diagnoses, as defined in the Diagnostic Criteria (DC)/TMD, among dental students. The secondary aim was to evaluate the prevalence and association of behavioural and psychosocial factors in relation to DC/TMD diagnoses. MATERIALS AND METHODS: The study was conducted among undergraduate dental students during the second semester of their third year at the Department of Odontology, Medical Faculty, Umeå University, Sweden...
February 18, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29457438/-ct-and-mri-manifestation-of-primary-spinal-large-b-cell-lymphoma
#3
Ping Tian, Kai Jiang, Zhi-Qiang Cai, Yong-Tao Wang, Sheng-de Deng
OBJECTIVE: To investigate CT and MRI characteristics of primary spinal large B cell lymphoma. METHODS: CT and MRI data of 23 patients with primary spinal large B cell lymphoma confirmed by histopathology were retrospectively analyzed from March 2011 to August 2015. Among them, including 14 males and 9 females aged from 28 to 70 years old with an average of 53.4 years old. The clinical manifestation mainly focus on pain around spinal and minority peripheral nerve symptom...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457389/-study-on-the-risk-factors-for-the-misdiagnosis-of-femoral-head-osteonecrosis
#4
Zhi-Wei Chen, Tai-Xian Li, Xiao-Xu Wan, Rong-Tian Wang, Wei-Heng Chen
OBJECTIVE: To evaluate the status and risk factors for the misdiagnosis of femoral head osteonecrosis, providing the basis for accurate diagnosis of osteonecrosis of femoral head. METHODS: The data of 314 hospitalized patients were collected from March 2015 to March 2016, and the risk factors for osteonecrosis of femoral head were analyzed by Logistic regression model. Misdiagnosis was defined that the diagnosis given on the first time was different from that on the second time or that given by expert group with the same symptoms and signs...
November 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457362/a-multinational-observational-investigation-of-illness-perceptions-and-quality-of-life-among-patients-with-a-fontan-circulation
#5
Christina E Holbein, Nicholas D Fogleman, Kevin Hommel, Silke Apers, Jessica Rassart, Philip Moons, Koen Luyckx, Maayke A Sluman, Junko Enomoto, Bengt Johansson, Hsiao-Ling Yang, Mikael Dellborg, Raghavan Subramanyan, Jamie L Jackson, Werner Budts, Adrienne H Kovacs, Stacey Morrison, Martha Tomlin, Kathy Gosney, Alexandra Soufi, Katrine Eriksen, Corina Thomet, Malin Berghammer, Luis Alday, Edward Callus, Susan M Fernandes, Maryanne Caruana, Samuel Menahem, Stephen C Cook, Gwen R Rempel, Kamila White, Paul Khairy, Shelby Kutty, Gruschen Veldtman
OBJECTIVE: First, to compare QOL and illness perceptions between patients with a Fontan circulation and patients with anatomically simple defects (ie, atrial septal defects [ASD] or ventricular septal defects [VSD]). Second, to explore illness perceptions as a mediator of the association between congenital heart disease (CHD) diagnosis and QOL. DESIGN: Cross-sectional observational study. SETTING: Twenty-four cardiology centers from 15 countries across five continents...
February 18, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29457355/visceral-obesity-is-a-significant-risk-factor-for-incisional-hernia-after-laparoscopic-colorectal-surgery-a-single-center-review
#6
Masateru Yamamoto, Yuji Takakura, Satoshi Ikeda, Toshiyuki Itamoto, Takashi Urushihara, Hiroyuki Egi
INTRODUCTION: Although laparoscopic surgery uses relatively small incisions, incisional hernia after surgery is not uncommon. However, the incidence of incisional hernia and its risk factors are not well known. The purpose of our study was to investigate risk factors for incisional hernia after laparoscopic colorectal cancer surgery. METHODS: The study group consisted of 212 patients who underwent laparoscopic colorectal cancer surgery at Hiroshima Prefectural Hospital between November 2008 and October 2013...
February 19, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29457309/severe-intestinal-malabsorption-associated-with-ace-inhibitor-or-angiotensin-receptor-blocker-treatment-an-observational-cohort-study-in-germany-and-italy
#7
Peter Malfertheiner, Claudio Ripellino, Nazarena Cataldo
PURPOSE: The angiotensin II receptor blocker (ARB) olmesartan has been recently associated with sprue-like enteropathy (SLE), a gastrointestinal condition characterized by intestinal malabsorption (IM) and severe diarrhea. Whether the increased risk of SLE is substance-specific or a class effect involving all ARBs is uncertain. The aim of this study is to assess the risk of enteropathy associated with ARBs and angiotensin converting enzyme inhibitors (ACE-i) by using data from large administrative and claim databases...
February 19, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29457270/clinical-and-echocardiographic-characteristics-of-patients-in-sinus-rhythm-normal-left-ventricular-function-and-indeterminate-diastolic-function
#8
Matan Shimron, Lynne Williams, Yevgeni Hazanov, Diab Ghanim, Wadia Kinany, Offer Amir, Shemy Carasso
BACKGROUND: Diastolic dysfunction (DDFx) is the major underlying mechanism of heart failure with preserved left ventricular ejection fraction (EF). Yet, the echocardiographic diagnosis of DDFx in patients in sinus rhythm is challenging and up to 25% of studies have discrepant measures making assessment of DDFx indeterminate. We aimed to describe the clinical and echocardiographic characteristics of patients with indeterminate diastolic function compared to patients with definite normal and abnormal diastolic function...
February 19, 2018: Echocardiography
https://www.readbyqxmd.com/read/29456855/metformin-and-aspirin-treatment-could-lead-to-an-improved-survival-rate-for-type-2-diabetic-patients-with-stage-ii-and-iii-colorectal-adenocarcinoma-relative-to-non-diabetic-patients
#9
Ariella De Monte, Davide Brunetti, Luigi Cattin, Francesca Lavanda, Erica Naibo, Maria Malagoli, Giorgio Stanta, Serena Bonin
Metformin, the drug of choice in the treatment of type 2 diabetes mellitus (DM2), in addition to aspirin (ASA), the drug prescribed for cardioprotection of diabetic and non-diabetic patients, have an inhibitory effect on cancer cell survival. The present population-based study conducted in the province of Trieste (Italy), aimed to investigate the prevalence of DM2 in patients with colorectal adenocarcinoma (CRC) and survival for CRC in diabetic and nondiabetic patients. All permanent residents diagnosed with a CRC between 2004 and 2007 were ascertained through the regional health information system...
March 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29456775/interethnic-variations-and-clinical-features-of-spondyloarthropathies-in-a-middle-eastern-country
#10
Mohammed Kamil Quraishi, Humeira Badsha, Bhavna Khan, Muhammad Shahzeb, Srilakshmi Hegde, Ayman Mofti, Kong Kok Ooi
Objectives: The study aimed to demonstrate the interethnic differences and clinical features of Spondyloarthropathy(SpA) patients in a diverse Middle Eastern Country. Methods: A retrospective review of medical records to collect the required data was conducted for SpA patients at two study institutions in the United Arab Emirates. Results: Of 141 SpA patients found, 88 AS(Ankylosing Spondylitis) patients and 53 'other SpA' patients were identified...
2018: Open Rheumatology Journal
https://www.readbyqxmd.com/read/29456728/values-of-mir-34a-and-mir-218-expression-in-the-diagnosis-of-cervical-cancer-and-the-prediction-of-prognosis
#11
Ping Wang, Guanyun Zhai, Yunyan Bai
The expression levels of microribonucleic acid 34a (miR-34a) and miR-218 in the serum and tumor tissues of patients with cervical cancer were investigated to explore their relationship with the diagnosis of cervical cancer. Fifty patients with cervical cancer were selected, and 30 normal patients were selected as the control group. The expression levels of miR-34a and miR-218 were detected by quantitative real-time polymerase chain reaction. The relationship between the expression of miR-34a and miR-218 was analyzed using Pearson's correlation coefficient, and the receiver operating characteristic (ROC) curve was plotted for the analysis of values of the expression of miR-34a and miR-218...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29456675/correlation-between-ppar-%C3%AE-methylation-level-in-peripheral-blood-and-atherosclerosis-of-nafld-patients-with-dm
#12
Jianghua Ju, Qingxian Huang, Jing Sun, Xiaoyun Zhao, Xiuli Guo, Yongcheng Jin, Wenjie Ma, Wenhui Wang
We investigated the correlation between the methylation levels of peroxisome proliferator-activated receptor-α (PPAR-α) in the peripheral blood and atherosclerosis in patients with nonalcoholic fatty liver disease (NAFLD) with diabetes mellitus (DM). A total of 50 normal subjects (group N) and 50 NAFLD patients with DM (group M) were selected at Qilu Hospital of Shandong University. The levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) in groups N and M were detected...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456353/the-utility-of-preoperative-acth-cortisol-ratio-for-the-diagnosis-and-prognosis-of-cushing-s-disease
#13
Alev Selek, Berrin Cetinarslan, Zeynep Canturk, Ilhan Tarkun, Ozlem Zeynep Akyay, Burak Cabuk, Savas Ceylan
Purpose: Cushing's syndrome (CS) is a rare disease having diagnostic difficulties. Many diagnostic tests have been defined but none of these are diagnostic alone. Determination of the cause is another problem which sometimes requires more sophisticated and invasive procedures. Therefore, we aimed to evaluate the utility of pretreatment plasma adrenocorticotropic hormone (ACTH)/cortisol ratios in patients with confirmed endogenous CS for the diagnosis and differential diagnosis of CS. Materials and Methods: This retrospective evaluation included 145 patients with the diagnosis of CS, 119 patients with Cushing's disease (CD), and 26 patients with ACTH-independent CS (AICS), in a university hospital...
January 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29456161/the-effect-of-lrrk2-mutations-on-the-cholinergic-system-in-manifest-and-premanifest-stages-of-parkinson-s-disease-a-cross-sectional-pet-study
#14
Shu-Ying Liu, Daryl J Wile, Jessie Fanglu Fu, Jason Valerio, Elham Shahinfard, Siobhan McCormick, Rostom Mabrouk, Nasim Vafai, Jess McKenzie, Nicole Neilson, Alexandra Perez-Soriano, Julieta E Arena, Mariya Cherkasova, Piu Chan, Jing Zhang, Cyrus P Zabetian, Jan O Aasly, Zbigniew K Wszolek, Martin J McKeown, Michael J Adam, Thomas J Ruth, Michael Schulzer, Vesna Sossi, A Jon Stoessl
BACKGROUND: Markers of neuroinflammation are increased in some patients with LRRK2 Parkinson's disease compared with individuals with idiopathic Parkinson's disease, suggesting possible differences in disease pathogenesis. Previous PET studies have suggested amplified dopamine turnover and preserved serotonergic innervation in LRRK2 mutation carriers. We postulated that patients with LRRK2 mutations might show abnormalities of central cholinergic activity, even before the diagnosis of Parkinson's disease...
February 15, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/29455458/diagnosis-presentation-and-initial-severity-of-autoimmune-hepatitis-aih-in-patients-attending-28-hospitals-in-the-uk
#15
Victoria Gordon, Ratul Adhikary, Victoria Appleby, Debasis Das, James Day, Toby Delahooke, Selena Dixon, David Elphick, Claire Hardie, Barbara Hoeroldt, Patricia Hooper, John Hutchinson, Rebecca Jones, Faisal Khan, Guruprasad P Aithal, John McGonigle, Andrew Nelson, Alick Nkhoma, Stavroula Pelitari, Martin Prince, Annell Prosser, Vinay Sathanarayana, Sophia Savva, Naina Shah, Sushma Saksena, Sreedhari Thayalasekaran, Deven Vani, Andrew Yeoman, Dermot Gleeson
BACKGROUND AND AIMS: There is limited information regarding patients with AIH outside relatively few large centres. We describe here the presenting features of patients with AIH, collected as part of an audit involving 28 UK hospitals. METHODS: Patients (incident since 1/1/2007 or prevalent since 1/1/2000) were >18 years and either met 1999 International AIH Group (IAIHG) diagnostic criteria (n=1164), or received immunosuppressive therapy for clinically diagnosed AIH (n=103)...
February 17, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29455399/human-figure-drawing-distinguishes-alzheimer-s-patients-a-cognitive-screening-test-study
#16
Michelangelo Stanzani Maserati, Renato D'Onofrio, Corrado Matacena, Luisa Sambati, Federico Oppi, Roberto Poda, Maddalena De Matteis, Ilaria Naldi, Rocco Liguori, Sabina Capellari
To study human figure drawing in a group of Alzheimer's disease (AD) patients and compare it with a group of patients with mild cognitive impairment (MCI) and controls. We evaluated consecutive outpatients over a one-year period. Patients were classified as affected by AD or by MCI. All patients and controls underwent a simplified version of the human-figure drawing test and MMSE. A qualitative and quantitative analysis of all human figures was obtained. 112 AD, 100 MCI patients and 104 controls were enrolled...
February 17, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29455009/protecting-an-adult-identity-a-grounded-theory-of-supportive-care-for-young-adults-recently-diagnosed-with-cancer
#17
Louise Soanes, Faith Gibson
BACKGROUND: For adolescents and young adults living in high-income countries cancer remains the most common disease-related death. Increasing survival rates and projected longevity are positive outcomes, although long-term consequences of cancer and/or its treatment will likely increase the global burden of cancer. In low and middle-income countries the impact and needs of young adults with cancer are largely unknown and require further attention. However, universal studies have revealed that cancer-related needs for this group are multifactorial, complex and largely unmet...
January 31, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29454976/defective-endogenous-pain-modulation-in-fibromyalgia-a-meta-analysis-of-temporal-summation-and-conditioned-pain-modulation-paradigms
#18
REVIEW
Anthony Terrence O'Brien, Alicia Deitos, Yolanda Triñanes Pego, Felipe Fregni, Maria Teresa Carrillo-de-la-Peña
To study the characteristics of temporal summation (TS) and conditioned pain modulation (CPM) in fibromyalgia (FM) patients, we systematically searched Pubmed and EMBASE for studies using TS or CPM comparing FM patients to healthy controls. We computed Hedge's g, risk of bias, sensitivity analysis and meta-regression tests with 10000 Monte-Carlo permutations. Twenty-three studies (625 female/23 male FM patients and 591 female/81 male healthy controls) were included. The meta-analyses showed an effect size of 0...
February 15, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29454970/increased-cerebrospinal-fluid-complement-c5-levels-in-major-depressive-disorder-and-schizophrenia
#19
Takashi Ishii, Kotaro Hattori, Tomoko Miyakawa, Kentaro Watanabe, Shinsuke Hidese, Daimei Sasayama, Miho Ota, Toshiya Teraishi, Hiroaki Hori, Sumiko Yoshida, Akihiko Nunomura, Kazuyuki Nakagome, Hiroshi Kunugi
Inflammation has been implicated in a variety of psychiatric disorders. We aimed to determine whether levels of complement C5 protein in the cerebrospinal fluid (CSF), which may reflect activation of the complement system in the brain, are altered in patients with major psychiatric disorders. Additionally, we examined possible associations of CSF C5 levels with clinical variables. Subjects comprised 89 patients with major depressive disorder (MDD), 66 patients with bipolar disorder (BPD), 96 patients with schizophrenia, and 117 healthy controls, matched for age, sex, and ethnicity (Japanese)...
February 15, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29454684/behavior-and-productivity-of-cows-milked-in-automated-systems-before-diagnosis-of-health-disorders-in-early-lactation
#20
M T M King, S J LeBlanc, E A Pajor, T C Wright, T J DeVries
Associations of electronically recorded data were examined before diagnosis of health disorders in early-lactation cows in herds with automated milking systems (AMS). Rumination time, activity, and milk yield data were collected for 8 mo for 605 early-lactation cows in 9 commercial AMS herds. Using multivariable generalized linear regression models controlling for parity and days in milk, data were examined relative to the day of diagnosis for health disorders occurring in absence of, or at least 14 d before, another disorder: mastitis (n = 13), new cases of lameness (n = 45), subclinical ketosis (SCK; n = 113), and purulent vaginal discharge (n = 49)...
February 14, 2018: Journal of Dairy Science
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