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https://www.readbyqxmd.com/read/29674405/localised-perforation-of-locally-advanced-transverse-colon-cancer-with-spontaneous-colocutaneous-fistula-formation-a-clinical-challenge
#1
Nikita Wadhwani, Deepak Kumar Diwakar
Colon cancer can present with complications such as obstruction, perforation and bleeding. The clinical presentation has been recognised as an independent prognostic factor for morbidity and mortality. 1 We present a rare case of localised perforation of a locally advanced colon cancer arising from mid-transverse colon in an elderly woman in the absence of widely metastatic disease with eventual cutaneous involvement of the overlying skin by direct extension, resulting in formation of colocutaneous fistula...
April 19, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29666026/cervical-cancer-state-of-the-science-from-angiogenesis-blockade-to-checkpoint-inhibition
#2
REVIEW
Lindsey E Minion, Krishnansu S Tewari
Vascular endothelial growth factor (VEGF) has emerged as a therapeutic target in several malignancies, including cervical cancer. Chemotherapy doublets combined with the fully humanized monoclonal antibody, bevacizumab, now constitute first-line therapy for women struggling with recurrent/metastatic cervical carcinoma. Regulatory approval for this indication was based on the phase III randomized trial, GOG 240, which demonstrated a statistically significant and clinically meaningful improvement in overall survival when bevacizumab was added to chemotherapy: 17...
March 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29628185/revisiting-colorectal-cancer-animal-model-an-improved-metastatic-model-for-distal-rectosigmoid-colon-carcinoma
#3
Rui Caetano-Oliveira, Marcos António Gomes, Ana Margarida Abrantes, Edgar Tavares-Silva, Marco Carvalho Oliveira, Mafalda Laranjo, Débora Basílio Queirós, João Casalta-Lopes, Salomé Pires, Lina Carvalho, Rosa Gouveia, Paulo Rodrigues Santos, Denise Gonçalves Priolli, José Guilherme Tralhão, Maria Filomena Botelho
Colorectal cancer (CRC) is the second most frequent and fatal cancer in Western countries. Understanding its biology with different incidence along the colon and rectum, genetic profile and how these factors contribute to local/distant progression, has been hampered by the lack of a suitable CRC model. We report a reproducible model, using human CRC cell lines (CL) (WiDr, LS1034, C2BBe1) injected (1 × 107 cells/animal) in RNU rats (n = 55) which underwent cecostomy and descending colostomy with mucosal-cutaneous fistula of the sigmoid colon...
March 13, 2018: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/29625723/infectious-complications-in-head-and-neck-surgery-porto-oncology-centre-retrospective-analysis
#4
Miguel Sá Breda, Joaquim Castro Silva, Eurico Monteiro
OBJECTIVE: To analyze the impact of infectious complications and microbiology in the postoperative period after major oncologic neck surgeries. METHODS: A retrospective study conducted in an oncology center, including all the consecutive patients who developed infectious complications after major neck cancer surgery, from October 2012 to May 2016 (44 months). Among other data, we collected TNM stage, ASA score, body mass index, comorbidities and habits, pre and postoperative hemoglobin levels, albumin serum levels, pre-surgical treatments, length of inpatient stay, isolated microbiological agents and the recorded complications and mortality rate...
April 3, 2018: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29619903/healing-of-spongiosus-cutaneous-fistula-with-hyperbaric-oxygen-therapy-hbot-a-case-report
#5
Pier A Della Camera, Gianmartin Cito, Simone Morselli, Francesco Sessa, Davide Facchiano, Andrea Cocci, Mauro Gacci, Sergio Serni, Marco Carini, Alessandro Natali
INTRODUCTION: We present a case of a spongiosus-cutaneous fistula in a 39-year-old man with recurrent episodes of cutaneous abscess in dorsal middle third penis (5 × 3 cm) treated with Hyperbaric Oxygen Therapy (HBOT). CASE REPORT: After emptying nodular abscess, the patient was noncompliant for further surgery. Therefore, it was suggested the association between HBOT and antibiotic therapy. HBOT is carried out in a hyperbaric room, where the internal pressure is increased (compression phase) by entering compressed air up to 283...
February 2018: Urologia
https://www.readbyqxmd.com/read/29619342/never-over-until-it-is-over-carotid-cutaneous-fistula
#6
Craig Kornbau, Michael S Firstenberg
No abstract text is available yet for this article.
January 2018: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/29619341/right-carotid-cutaneous-fistula-and-right-carotid-pseudoaneurysm-formation-secondary-to-a-chronically-infected-polyethylene-terephthalate-patch
#7
W T Hillman Terzian, Samuel Schadt, Sharvil U Sheth
Carotid endarterectomy (CEA) remains the treatment for significant carotid stenosis and stroke prevention. Approximately 100,000 CEAs are performed in the United States every year. Randomized trials have demonstrated an advantage of patch carotid angioplasty over primary closure. Complications from patches include thrombosis, transient ischemic attack, stroke, restenosis, pseudoaneurysm (PA), and infection. PA after CEA is rare, with a reported average of 0.37% of cases. We describe an unusual case of PA after polyethylene terephthalate (PTFE) patching for CEA...
January 2018: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/29594086/the-megameatus-intact-prepuce-variant-of-hypospadias-use-of-the-inframeatal-vascularized-flap-for-surgical-correction
#8
Marc Cendron
Introduction: The megameatus intact prepuce (MIP) variant of hypospadias is a rare variant of hypospadias that is diagnosed either early at the time of circumcision or later as the foreskin is retracted. The true incidence of the anomaly is difficult to determine precisely as some patient never come to medical attention but is felt to under 5% of all cases of hypospadias. The purposes of this study are to review the embryology and clinical findings of MIP and then, in light of a personal experience, present a series of patients evaluated for MIP who were treated with a modification of the Mathieu technique...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29593927/a-case-of-rare-complication-of-inguinal-parietoplasty-according-to-lichtenstein-entero-cutaneous-fistula
#9
K B Kouakou, K I Anzoua, M Traore, B K I Leh, A B N'Dri, A S Ekra, B A Kouakou, R Lebeau, B Diané
Lichtenstein intervention is currently the classic model of the regulated treatment of inguinal hernias by direct local approach. This "tension-free" technique satisfies both patients and practitioners. However, it does not often evade severe complications of parietal surgery. The authors report their treatment experience in rural Africa of a late enterocutaneous fistula which aggravated an inguinal hernia repair according to the Lichtenstein procedure. Physiopathology, diagnosis, and treatment of that disease are analyzed in the light of literature...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29588855/phage-treatment-of-an-aortic-graft-infected-with-pseudomonas-aeruginosa
#10
Benjamin K Chan, Paul E Turner, Samuel Kim, Hamid R Mojibian, John A Elefteriades, Deepak Narayan
Management of prosthetic vascular graft infections caused by Pseudomonas aeruginosa can be a significant challenge to clinicians. These infections often do not resolve with antibiotic therapy alone due to antibiotic resistance/tolerance by bacteria, poor ability of antibiotics to permeate/reduce biofilms and/or other factors. Bacteriophage OMKO1 binding to efflux pump proteins in P. aeruginosa was consistent with an evolutionary trade-off: wildtype bacteria were killed by phage whereas evolution of phage-resistance led to increased antibiotic sensitivity...
2018: Evolution, Medicine, and Public Health
https://www.readbyqxmd.com/read/29544172/segmental-neurofibromatosis-type-1-complicated-with-multiple-intracranial-arteriovenous-fistulas-a-case-study
#11
Dian He, Yuan Li, Yunli Yu, Gang Cai, Fu Ouyang, Yuchan Lin, Hongjuan Lu, Lan Chu
Neurofibromatosis type 1 (NF1) is a rare autosomal dominant disorder that primarily affects the skin and the nervous system. This condition is called segmental NF1 (also called neurofibromatosis type V) when clinical features are limited to one area of the body. Segmental NF1 is generally thought to result from somatic mosaicism due to a postzygotic mutation in the NF1 gene, thus a test for NF1 gene abnormalities in peripheral blood is usually negative. Here we report a 31-year-old male presenting with epileptic seizures, who had a history of neurofibromas confirmed by biopsy, but lacked a family history of neurofibromatosis...
March 1, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29515214/complications-of-non-continent-cutaneous-urinary-diversion-in-adults-with-spinal-cord-injury-a-retrospective-study
#12
Cyrille Guillot-Tantay, Emmanuel Chartier-Kastler, Marie-Aimée Perrouin-Verbe, Pierre Denys, Priscilla Léon, Véronique Phé
STUDY DESIGN: Retrospective cohort study. OBJECTIVES: To report the long-term complications of non-continent cutaneous urinary diversion (NCCUD) in adult patients with spinal cord injury (SCI). SETTING: Hospital in Paris, France. METHODS: A retrospective single center study included all adult patients with SCI who underwent an ileal conduit between 1997 and 2014. Early complications were reported according to Clavien-Dindo classification...
March 7, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29486682/successful-treatment-of-a-persistent-oroantral-fistula-via-transbuccal-and-transnasal-endoscopic-debridement-in-a-horse
#13
Knut Nottrott, Cécile De Guio, Michael Schramme
We report an unusual case of a young Quarter Horse with a large dental fracture fragment displaced into the maxillary sinus, leaving an oroantral communication that caused food impaction and metaplastic calcification in the sinus and facial deformation with cutaneous fistulation. Oral extraction of a remaining tooth fragment from its alveolus was succeeded by a maxillary sinusotomy for removal of the abnormal sinus contents. Since the oroantral fistula did not heal spontaneously following the placement of a silicone dental prosthesis, minimally invasive transbuccal and transnasal endoscopic approaches were used to encourage closure of the oroantral fistula by alveolar granulation...
March 2018: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/29480882/delayed-diagnosis-of-xanthogranulomatous-pyelonephritis-in-a-quadriplegic-patient-with-uncontrolled-cutaneous-fistula-a-case-report
#14
Jae-Hyuk Yang, Jin Yong Shin, Si-Gyun Roh, Suk-Choo Chang, Nae-Ho Lee
RATIONALE: Xanthogranulomatous pyelonephritis (XGP) is a chronic destructive granulomatous inflammation that is characterized by urinary tract obstruction and invasion of the renal parenchyma. Although rare, XGP can lead to fatal complications, including perinephric inflammation, psoas abscess, and cutaneous fistula. PATIENT CONCERNS: A quadriplegic patient initially presented to the hospital with a chronic open wound and cutaneous fistula. DIAGNOSES: Abdominal computed tomography revealed a renal obstructing stone and enlarged right kidney with a perinephric fluid collection that communicated with the cutaneous fistula...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29479416/need-brooks-no-delay-peritoneo-cutaneous-fistula-formation-secondary-to-gallstone-dropped-at-laparoscopic-cholecystectomy-20-years-previously-a-case-report
#15
Luke Nugent, Palanichamy Chandran
Dropped gallstones, in addition to inadvertent damage to the biliary tree, is a complication seen in laparoscopic cholecystectomy (LC) far more frequently than the open procedure. It can result in symptomatic abscess formation, and given its relative rarity, can present a diagnostic challenge. We present the case of a lady whose dropped gallstone resulted in a peritoneo-cutaneous fistula, over 20 years on from her LC.
February 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29402607/conservative-treatment-for-cutaneous-fistula-resulted-from-abscess-formation-in-patients-with-tuberculous-cervical-lymphadenitis
#16
Bo Hae Kim, Yung Jin Jeon, Young Ju Jin, Woo-Jin Jeong, Sung Joon Park, Soon-Hyun Ahn
OBJECTIVE: This study describes the clinical characteristics and course of conservative treatment using anti-Tb medication and dressing in patients with tuberculous cervical fistula resulting from abscess formation, and to investigate factors prognostic of dressing and treatment duration. METHODS: The medical records of patients with tuberculous cervical lymphadenitis were reviewed, and 38 of these patients who presented with cutaneous fistula that resulted from abscess formation were included in the study...
February 2, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29384913/combing-a-novel-device-and-negative-pressure-wound-therapy-for-managing-the-wound-around-a-colostomy-in-the-open-abdomen-a-case-report
#17
Xiaofang Sun, Shaohan Wu, Ting Xie, Jianping Zhang
RATIONALE: An open abdomen complicated with small-bowel fistulae becomes a complex wound for local infection, systemic sepsis and persistent soiling irritation by intestinal content. While controlling the fistulae drainage, protecting surrounding skin, healing the wound maybe a challenge. PATIENT CONCERNS: In this paper we described a 68-year-old female was admitted to emergency surgery in general surgery department with severe abdomen pain. Resection part of the injured small bowel, drainage of the intra-abdominal abscess, and fashioning of a colostomy were performed...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29332920/aorto-cutaneous-fistula-after-surgical-treatment-of-stanford-type-a-aortic-dissection
#18
Chenyu Zhao, Zhicheng Zhu, Xiaomei Zheng, Kexiang Liu
An aorto-cutaneous fistula is a rare complication that occurs after aortic surgery. Due to its rarity, postoperative complications are not normally highlighted in most standard teaching. We report here a case of aorto-cutaneous fistula after surgical treatment of a Stanford type A aortic dissection (AD) in a 67-year-old Chinese male. The patient presented with severe right heart dysfunction and a mass was found in the upper-middle of his chest, which started bleeding in the next years. On admission, preoperative aortic computed tomography angiography (CTA) showed a huge hematoma located in the anterior superior mediastinum and a shunt between the embedding cavity of the aortic root and right atrium...
January 27, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29301065/pancreatic-necrosectomy-through-sinus-tract-endoscopy
#19
Mahesh Kumar Goenka, Usha Goenka, Md Yasin Mujoo, Indrajit Kumar Tiwary, Sanjay Mahawar, Vijay Kumar Rai
Background/Aims: Direct endoscopic pancreatic necrosectomy is increasingly being utilized to treat infected or symptomatic walled-off necrosis (WON) located close to the stomach or duodenum. Laterally-placed WON has traditionally been treated surgically. We evaluated a less utilized technique of sinus tract endoscopy (STE) for symptomatic laterally-placed WON. Methods: Two hundred seventy-six patients with acute pancreatitis admitted in our hospital, 32 had symptomatic or infected WON requiring intervention...
January 4, 2018: Clinical Endoscopy
https://www.readbyqxmd.com/read/29287855/branchial-anomalies-in-children-a-report-of-105-surgical-cases
#20
Wanpeng Li, Hongming Xu, Liming Zhao, Xiaoyan Li
BACKGROUND: Branchial anomalies (BAs) account for 20% of all congenital masses in children. We sought to review the incidence of involvement of individual anomalies, diagnostic methods, surgical treatment, and complications of BAs in children. In addition, we also classified our study and analyzed a congenital lower neck cutaneous fistula near the sternoclavicular joint that was thought to be the skin-side remnant of the fourth BAs. METHODS: We conducted a retrospective analysis of 105 children who were referred to our hospital from June 2009 to December 2016 for the treatment of BAs...
January 2018: International Journal of Pediatric Otorhinolaryngology
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