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https://www.readbyqxmd.com/read/28926576/receptor-for-advanced-glycation-end-products-and-world-trade-center-particulate-induced-lung-function-loss-a-case-cohort-study-and-murine-model-of-acute-particulate-exposure
#1
Erin J Caraher, Sophia Kwon, Syed H Haider, George Crowley, Audrey Lee, Minah Ebrahim, Liqun Zhang, Lung-Chi Chen, Terry Gordon, Mengling Liu, David J Prezant, Ann Marie Schmidt, Anna Nolan
World Trade Center-particulate matter(WTC-PM) exposure and metabolic-risk are associated with WTC-Lung Injury(WTC-LI). The receptor for advanced glycation end-products (RAGE) is most highly expressed in the lung, mediates metabolic risk, and single-nucleotide polymorphisms at the AGER-locus predict forced expiratory volume(FEV). Our objectives were to test the hypotheses that RAGE is a biomarker of WTC-LI in the FDNY-cohort and that loss of RAGE in a murine model would protect against acute PM-induced lung disease...
2017: PloS One
https://www.readbyqxmd.com/read/28913914/new-onset-of-asthma-and-job-status-change-among-world-trade-center-responders-and-workers
#2
Hyun Kim, Sherry Baron, Navneet K Baidwan, Adam Schwartz, Jacqueline Moline
BACKGROUND: Despite the high rates, the consequences of new onset asthma among the World Trade Center (WTC) responders in terms of the change in job status have not been studied. METHODS: This study consists of a cohort of 8132 WTC responders out of the total 25 787 responders who held a full-time job at the baseline visit, and participated in at least one follow-up visit. RESULTS: Overall, 34% of the study cohort changed their job status from full-time at a follow-up visit...
September 14, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28890218/serum-perfluoroalkyl-substances-and-cardiometabolic-consequences-in-adolescents-exposed-to-the-world-trade-center-disaster-and-a-matched-comparison-group
#3
Tony T Koshy, Teresa M Attina, Akhgar Ghassabian, Joseph Gilbert, Lauren K Burdine, Michael Marmor, Masato Honda, Dinh Binh Chu, Xiaoxia Han, Yongzhao Shao, Kurunthachalam Kannan, Elaine M Urbina, Leonardo Trasande
BACKGROUND: Large amounts of various chemical contaminants, including perfluoroalkyl substances (PFASs), were released at the time of the World Trade Center (WTC) disaster. Thousands of children who lived and/or attended school near the disaster site were exposed to these substances but few studies have examined the possible consequences related to these exposures. OBJECTIVES: To examine the relationship of PFASs serum levels with cardiometabolic profile in children and adolescents enrolled in the World Trade Center Health Registry (WTCHR) and a matched comparison group...
September 7, 2017: Environment International
https://www.readbyqxmd.com/read/28886483/a-window-based-time-series-feature-extraction-method
#4
Deniz Katircioglu-Öztürk, H Altay Güvenir, Ursula Ravens, Nazife Baykal
This study proposes a robust similarity score-based time series feature extraction method that is termed as Window-based Time series Feature ExtraCtion (WTC). Specifically, WTC generates domain-interpretable results and involves significantly low computational complexity thereby rendering itself useful for densely sampled and populated time series datasets. In this study, WTC is applied to a proprietary action potential (AP) time series dataset on human cardiomyocytes and three precordial leads from a publicly available electrocardiogram (ECG) dataset...
August 9, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28840161/impairment-of-cerebral-autoregulation-in-pediatric-extracorporeal-membrane-oxygenation-associated-with-neuroimaging-abnormalities
#5
Fenghua Tian, Michael Craig Morriss, Lina Chalak, Ramgopal Venkataraman, Chul Ahn, Hanli Liu, Lakshmi Raman
Extracorporeal membrane oxygenation (ECMO) is a life-supporting therapy for critically ill patients with severe respiratory and/or cardiovascular failure. Cerebrovascular impairment can result in hemorrhagic and ischemic complications commonly seen in the patients supported on ECMO. We investigated the degree of cerebral autoregulation impairment during ECMO as well as whether it is predictive of neuroimaging abnormalities. Spontaneous fluctuations of mean arterial pressure (MAP) and cerebral tissue oxygen saturation ([Formula: see text]) were continuously measured during the ECMO run...
October 2017: Neurophotonics
https://www.readbyqxmd.com/read/28666154/respiratory-problems-and-anxiety-sensitivity-in-smoking-lapse-among-treatment-seeking-smokers
#6
Michael J Zvolensky, Rubén Rodríguez-Cano, Daniel J Paulus, Roman Kotov, Evelyn Bromet, Adam Gonzalez, Kara Manning, Benjamin J Luft
PURPOSE: The current study examined whether the interaction of lower respiratory symptoms and anxiety sensitivity is related to smoking lapse in the context of smoking cessation. METHOD: Participants were adult daily smokers (N=60) exposed to the World Trade Center (WTC) disaster who were in a smoking cessation treatment program (75.0% male, 50.6years old [SD=9.2], and current smoking rate was 17.6 cigarettes per day (SD=10.6). RESULTS: Results indicated that the interaction between lower respiratory symptoms and anxiety sensitivity was a significant predictor of greater risk for lapse (i...
December 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28631184/willingness-to-communicate-orally-the-case-of-iranian-efl-learners
#7
Elaheh Tavakoli, Mohammad Davoudi
This study sets out to develop a questionnaire on willingness to communicate (WTC) orally specific to English as a Foreign Language setting. It also aims to investigate the effect of three independent variables of interlocutor, age and gender on the same construct of WTC orally. Exploratory factor analysis resulted in three dimensions to WTC, namely WTC with teacher, with classmate, and stranger. Also Cronbach's alpha of .86 indicated a high internal consistency. Mixed between-within subjects analysis of variance was used to assess the impact of interlocutors, age and gender on participants' WTC across the three WTC subscale scores...
June 19, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/28626126/conduct-of-occupational-health-during-major-disasters-a-comparison-of-literature-on-occupational-health-issues-in-the-world-trade-center-terrorist-attack-and-the-fukushima-nuclear-power-plant-accident
#8
Hiroyuki Toyoda, Koji Mori
Workers who respond to large-scale disasters can be exposed to health hazards that do not exist in routine work. It is assumed that learning from past cases is effective for preparing for and responding to such problems, but published information is still insufficient. Accordingly, we conducted a literature review about the health issues and occupational health activities at the World Trade Center (WTC) terrorist attack and at the Fukushima Nuclear Power Plant accident to investigate how occupational health activities during disasters should be conducted...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/28622920/post-9-11-sarcoidosis-in-wtc-exposed-firefighters-and-emergency-medical-service-workers
#9
Mayris P Webber, Jennifer Yip, Rachel Zeig-Owens, William Moir, Patompong Ungprasert, Cynthia S Crowson, Charles B Hall, Nadia Jaber, Michael D Weiden, Eric L Matteson, David J Prezant
INTRODUCTION: The World Trade Center (WTC) disaster released a huge quantity and variety of toxicants into the environment. To-date, studies from each of the three major cohorts of WTC-exposed workers have suggested "greater than expected" numbers of post-9/11 cases in some workers. We undertook this study to estimate the incidence of post-9/11 sarcoidosis in ∼13,000 male firefighters and EMS workers enrolled in The Fire Department of the City of New York (FDNY) WTC Health Program; to compare FDNY incidence to rates from unexposed, demographically similar men in the Rochester Epidemiology Project (REP); and, to examine rates by level of WTC exposure...
June 7, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28592993/can-we-use-short-rotation-coppice-poplar-for-sugar-based-biorefinery-feedstock-bioconversion-of-2-year-old-poplar-grown-as-short-rotation-coppice
#10
Chang Dou, Wilian F Marcondes, Jessica E Djaja, Renata Bura, Rick Gustafson
BACKGROUND: Feedstock cost is a substantial barrier to the commercialization of lignocellulosic biorefineries. Poplar grown using a short rotation coppice (SRC) system has the potential to provide a low-cost feedstock and economically viable sugar yields for fuels and chemicals production. In the coppice management regime, poplars are harvested after 2 years' growth to develop the root system and establish the trees. The biomass from these 2-year-old trees is very heterogeneous, and includes components of leaf, bark, branch, and wood chip...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28586254/hospitalizations-for-asthma-among-adults-exposed-to-the-september-11-2001-world-trade-center-terrorist-attack
#11
Sara A Miller-Archie, Hannah T Jordan, Howard Alper, Juan P Wisnivesky, James E Cone, Stephen M Friedman, Robert M Brackbill
OBJECTIVE: We described the patterns of asthma hospitalization among persons exposed to the 2001 World Trade Center (WTC) attacks, and assessed whether 9/11-related exposures or comorbidities, including posttraumatic stress disorder (PTSD) and gastroesophageal reflux symptoms (GERS), were associated with an increased rate of hospitalization. METHODS: Data for adult enrollees in the WTC Health Registry, a prospective cohort study, with self-reported physician-diagnosed asthma who resided in New York State on 9/11 were linked to administrative hospitalization data to identify asthma hospitalizations during September 11, 2001-December 31, 2010...
June 6, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28370461/hurricane-sandy-exposure-and-the-mental-health-of-world-trade-center-responders
#12
Evelyn J Bromet, Sean Clouston, Adam Gonzalez, Roman Kotov, Kathryn M Guerrera, Benjamin J Luft
The psychological consequences of a second disaster on populations exposed to an earlier disaster have rarely been studied prospectively. Using a pre- and postdesign, we examined the effects of Hurricane Sandy on possible World Trade Center (WTC) related posttraumatic stress disorder (PTSD Checklist score of ≥ 50) and overall depression (major depressive disorder [MDD]; Patient Health Questionnaire depression score of ≥ 10) among 870 WTC responders with a follow-up monitoring visit at the Long Island WTC Health Program during the 6 months post-Hurricane Sandy...
April 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28341697/risk-factors-for-persistence-of-lower-respiratory-symptoms-among-community-members-exposed-to-the-2001-world-trade-center-terrorist-attacks
#13
Hannah T Jordan, Stephen M Friedman, Joan Reibman, Roberta M Goldring, Sara A Miller Archie, Felix Ortega, Howard Alper, Yongzhao Shao, Carey B Maslow, James E Cone, Mark R Farfel, Kenneth I Berger
OBJECTIVES: We studied the course of lower respiratory symptoms (LRS; cough, wheeze or dyspnoea) among community members exposed to the 9/11/2001 World Trade Center (WTC) attacks during a period of 12-13 years following the attacks, and evaluated risk factors for LRS persistence, including peripheral airway dysfunction and post-traumatic stress disorder (PTSD). METHODS: Non-smoking adult participants in a case-control study of post-9/11-onset LRS (exam 1, 2008-2010) were recruited for follow-up (exam 2, 2013-2014)...
June 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28324780/the-longitudinal-relationship-between-control-over-working-hours-and-depressive-symptoms-results-from-slosh-a-population-based-cohort-study
#14
Sophie C Albrecht, Göran Kecklund, Kristiina Rajaleid, Constanze Leineweber
BACKGROUND: Psychosocial work factors can affect depressive moods, but research is inconclusive if flexibility to self-determine working hours (work-time control, WTC) is associated with depressive symptoms over time. We investigated if either sub-dimension of WTC, control over daily hours and control over time off, was related to depressive symptoms over time and examined causal, reversed-causal, and reciprocal pathways. METHODS: The study was based on four waves of the Swedish Longitudinal Occupational Survey of Health which is a follow-up of representative samples of the Swedish working population...
June 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28321793/psychological-distress-in-parents-and-school-functioning-of-adolescents-results-from-the-world-trade-center-registry
#15
Lisa M Gargano, Tenzin Dechen, James E Cone, Steven D Stellman, Robert M Brackbill
Poor school-functioning can be indicative of parent and adolescent mental health and adolescent behavior problems. This study examined 472 adolescents enrolled in the World Trade Center (WTC) Health Registry, with a two-step path analysis, using regression-based models, to unravel the relationships between parent and adolescent mental health, adolescent behavior problems, and adolescent unmet healthcare need (UHCN) on the outcome school-functioning. WTC exposure was associated with UHCN and parental mental health was a significant mediator...
March 20, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28277702/pathway-from-ptsd-to-respiratory-health-longitudinal-evidence-from-a-psychosocial-intervention
#16
Monika A Waszczuk, Xiaotong Li, Evelyn J Bromet, Adam Gonzalez, Michael J Zvolensky, Camilo Ruggero, Benjamin J Luft, Roman Kotov
OBJECTIVE: Respiratory illness and posttraumatic stress disorder (PTSD) are common debilitating conditions that frequently co-occur. Observational studies indicate that PTSD, independently of smoking, is a major risk and maintenance factor for lower respiratory symptoms (LRS). The current study experimentally tested this etiologic pathway by investigating whether LRS can be reduced by treating PTSD symptoms. METHOD: Ninety daily smokers exposed to the World Trade Center (WTC) disaster (mean age 50 years, 28% female; 68% White) completed 8-session group-based weekly comprehensive trauma management and smoking cessation treatment that focused on skills to alleviate PTSD symptoms...
May 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28238121/leukocyte-inos-is-required-for-inflammation-and-pathological-remodeling-in-ischemic-heart-failure
#17
Justin R Kingery, Tariq Hamid, Robert K Lewis, Mohamed Ameen Ismahil, Shyam S Bansal, Gregg Rokosh, Tim M Townes, Suzanne T Ildstad, Steven P Jones, Sumanth D Prabhu
In the failing heart, iNOS is expressed by both macrophages and cardiomyocytes. We hypothesized that inflammatory cell-localized iNOS exacerbates left ventricular (LV) remodeling. Wild-type (WT) C57BL/6 mice underwent total body irradiation and reconstitution with bone marrow from iNOS(-/-) mice (iNOS(-/-)c) or WT mice (WTc). Chimeric mice underwent coronary ligation to induce large infarction and ischemic heart failure (HF), or sham surgery. After 28 days, as compared with WTc sham mice, WTc HF mice exhibited significant (p < 0...
March 2017: Basic Research in Cardiology
https://www.readbyqxmd.com/read/28229067/the-effect-of-world-trade-center-exposure-on-the-timing-of-diagnoses-of-obstructive-airway-disease-chronic-rhinosinusitis-and-gastroesophageal-reflux-disease
#18
Xiaoxue Liu, Jennifer Yip, Rachel Zeig-Owens, Jessica Weakley, Mayris P Webber, Theresa M Schwartz, David J Prezant, Michael D Weiden, Charles B Hall
OBJECTIVES: In a cohort of rescue/recovery workers exposed to the dust that resulted from the collapse of the World Trade Center (WTC), we assessed how a diagnosis of obstructive airways disease (OAD) affected the likelihood of a subsequent diagnosis of chronic rhinosinusitis (CRS) or gastroesophageal reflux disease (GERD). We also assessed whether OAD acted as a mediator of the association between exposure to the WTC rescue/recovery effort and CRS and GERD diagnoses. METHODS: In this prospective cohort study, we analyzed Fire Department of the City of New York physician diagnoses of OAD, CRS, and GERD that were first documented between September 11, 2001, and September 10, 2011, among 8,968 WTC-exposed firefighters...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28220095/don-t-lose-your-brain-at-work-the-role-of-recurrent-novelty-at-work-in-cognitive-and-brain-aging
#19
Jan Oltmanns, Ben Godde, Axel H Winneke, Götz Richter, Claudia Niemann, Claudia Voelcker-Rehage, Klaus Schömann, Ursula M Staudinger
Cognitive and brain aging is strongly influenced by everyday settings such as work demands. Long-term exposure to low job complexity, for instance, has detrimental effects on cognitive functioning and regional gray matter (GM) volume. Brain and cognition, however, are also characterized by plasticity. We postulate that the experience of novelty (at work) is one important trigger of plasticity. We investigated the cumulative effect of recurrent exposure to work-task changes (WTC) at low levels of job complexity on GM volume and cognitive functioning of middle-aged production workers across a time window of 17 years...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28157767/paresthesias-among-community-members-exposed-to-the-world-trade-center-disaster
#20
Michael Marmor, Yongzhao Shao, D Harshad Bhatt, Mark M Stecker, Kenneth I Berger, Roberta M Goldring, Rebecca L Rosen, Caralee Caplan-Shaw, Angeliki Kazeros, Deepak Pradhan, Marc Wilkenfeld, Joan Reibman
OBJECTIVE: Paresthesias can result from metabolic disorders, nerve entrapment following repetitive motions, hyperventilation pursuant to anxiety, or exposure to neurotoxins. We analyzed data from community members exposed to the World Trade Center (WTC) disaster of September 11, 2001, to evaluate whether exposure to the disaster was associated with paresthesias. METHODS: Analysis of data from 3141 patients of the WTC Environmental Health Center. RESULTS: Fifty-six percent of patients reported paresthesias at enrollment 7 to 15 years following the WTC disaster...
February 2, 2017: Journal of Occupational and Environmental Medicine
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