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Cervical Degeneration

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https://www.readbyqxmd.com/read/29142627/a-comparison-of-anterior-cervical-discectomy-and-fusion-versus-fusion-combined-with-artificial-disc-replacement-for-treating-3-level-cervical-spondylotic-disease
#1
Seo-Ryang Jang, Sang-Bok Lee, Kyoung-Suok Cho
Objective: The purpose of this study is to evaluate the efficacy and safety of 3-level hybrid surgery (HS), which combines fusion and cervical disc replacement (CDR), compared to 3-level fusionin patient with cervical spondylosis involving 3 levels. Methods: Patients in the anterior cervical discectomy and fusion (ACDF) group (n=30) underwent 3-level fusion and the HS group (n=19) underwent combined surgery with fusion and CDR. Clinical outcomes were evaluated using the visual analogue scale for the arm, the neck disability index (NDI), Odom criteria and postoperative complications...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29127511/adjacent-segment-degeneration-after-intervertebral-fusion-surgery-by-means-of-cervical-block-vertebrae
#2
Xinlong Ma, Yuren Du, Shuli Wang, Jianxiong Ma, Tao Wang, Mingjie Kuang, Baoyi Ma
BACKGROUND: The prevalence of cervical block vertebrae is unknown. Furthermore, there is no consensus on the cause of adjacent segment degeneration (ASD) after cervical fusion. QUESTIONS/PURPOSES: (1) What is the incidence of cervical block vertebrae? Is there a gender difference? (2) Among cervical block vertebrae cases, is ASD related to age and segment? And what is the specific relationship? (3) What are the imaging findings and characteristics of this disease? PATIENTS AND METHODS: We retrospectively diagnosed cervical block vertebrae cases with bony fusions in any segments of the cervical spine without intervertebral fusion surgery of 33,762 patients reported from 2006 to 2011 in north China...
November 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29108667/clinical-electrophysiological-genetic-and-imaging-features-of-six-chinese-han-patients-with-hereditary-neuropathy-with-liability-to-pressure-palsies-hnpp
#3
Bin Chen, Songtao Niu, Xingao Wang, Wei Li, Na Chen, Zaiqiang Zhang
Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal dominant peripheral neuropathy caused by mutations in the peripheral myelin protein 22 (PMP22) gene. This study summarizes the clinical, electrophysiological, genetic, and imaging features of six unrelated Chinese Han patients with HNPP. Age of onset was within the second decade in five patients, and 46 years of age in one patient. Weakness or numbness in a unilateral lower extremity was the most common symptom in 5 patients, and bilateral sensorineural hearing loss was also detected in one patient...
November 3, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29101465/changes-in-cervical-motion-after-cervical-spinal-motion-preservation-surgery
#4
Chi Heon Kim, Tae Hyun Park, Chun Kee Chung, Kyoung-Tae Kim, Yun Hee Choi, Seok-Won Chung
BACKGROUND: For patients with single-level cervical radiculopathy, various types of motion preservation surgeries, such as total disc replacement (TDR), posterior cervical foraminotomy (PCF) and posterior percutaneous endoscopic foraminotomy and discectomy (PECF), are available. In addition to motion preservation, the quality of motion is an important issue. The aim of the present study was to evaluate the influence of these surgeries on cervical motion by comparing the instantaneous axis of rotation (IAR) among PECF, TDR and PCF at the index and superior/inferior adjacent segments...
November 3, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29101314/clinical-and-radiological-analysis-of-bryan-cervical-artificial-disc-replacement-for-skip-multi-segment-cervical-spondylosis-long-term-follow-up-results
#5
Zikun Shang, Yingze Zhang, Di Zhang, Wenyuan Ding, Yong Shen
BACKGROUND The aim of this study was to retrospectively analyze the clinical and radiological efficacy of Bryan cervical artificial disc replacement (ADR) for "skip" multi-segment cervical spondylosis (SCS). MATERIAL AND METHODS We enrolled 49 patients with SCS treated with either Bryan cervical ADR (18 cases) or ACDF (31 cases). Each case was evaluated preoperatively and at more than 48 months postoperatively in follow-up using the JOA, NDI, and VAS. Cervical sagittal curvature, total cervical ROM, and degree of middle segments of motion were also evaluated...
November 4, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29076467/-analysis-of-the-results-of-total-cervical-disc-arthroplasty-using-a-m6-c-prosthesis-a-multicenter-study
#6
V A Byval'tsev, A A Kalinin, I A Stepanov, Yu Ya Pestryakov, V V Shepelev
Cervical spondylosis and intervertebral disc (IVD) degeneration are the most common cause for compression of the spinal cord and/or its roots. Total IVD arthroplasty, as a modern alternative to surgical treatment of IVD degeneration, is gaining popularity in many neurosurgical clinics around the world. Aim - the study aim was to conduct a multicenter analysis of cervical spine arthroplasty with an IVD prosthesis M6-C ('Spinal Kinetics', USA). MATERIAL AND METHODS: The study included 112 patients (77 males and 35 females)...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/29072013/-effects-of-chiropractics-on-intervertebral-disk-extracell-matrix-and-metabolic-enzymes-in-rats-with-cervical-spondylosis
#7
Li-Shan Huang, Ping-Ping Huang, Xiu-Bing Tong, Zhong-Li Li, Yan-Ping Fang, Jun Liao
OBJECTIVE: To observe the effect of chiropractics on intervertebral disk extracell matrix metalloproteinase (MMP)-1, MMP-3, MMP-13, cellular collagen type Ⅱ (COL-Ⅱ), tissue inhibitor 1 of metalloproteinase (TIMP-1) and extracellular matrix (ECM) in the rats with cervical spondylosis, so as to explore its mechanism underlying improvement of cervical spondylosis. METHODS: A total of 40 SD rats were randomized into a sham group, a model group, a chiropractics group and a mobic group, 8 rats in each one...
August 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29072008/-effect-of-nape-seven-needles-on-expression-of-dll-4-and-hes-1-in-cervical-intervertebral-disc-degeneration-rats
#8
Yan Lu, Qing-Si Shen, Meng Tian, Hong-Ling Jia, Yong-Chen Zhang
OBJECTIVE: To observe the effect of "Nape Seven Needles" on the expressions of Delta-like ligand 4 (Dll 4) and hairy and enhancer of split homolog 1(Hes 1) in cervical intervertebral disc degeneration(IVDD) rats, so as to explore its mechanism of deferring the degeneration of cervical intervertebral disc. METHODS: SD male rats were randomly divided into a normal group, a model group and a nape seven needles group (n=11 in each group). The IVDD model was established by static-dynamic imbalance method...
August 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29069048/predictive-factors-associated-with-neck-pain-in-patients-with-cervical-disc-degeneration-a-cross-sectional-study-focusing-on-modic-changes
#9
Lingde Kong, Weifeng Tian, Peng Cao, Haonan Wang, Bing Zhang, Yong Shen
The predictive factors associated with neck pain remain unclear. We conducted a cross-sectional study to assess predictive factors, especially Modic changes (MCs), associated with the intensity and duration of neck pain in patients with cervical disc degenerative disease.We retrospectively reviewed patients in our hospital from January 2013 to December 2016. Severe neck pain (SNP) and persistent neck pain (PNP) were the 2 main outcomes, and were assessed based on the numerical rating scale (NRS). Basic data, and also imaging data, were collected and analyzed as potential predictive factors...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29066708/survivorship-analysis-of-clinical-adjacent-segment-pathology-after-single-level-cervical-fusion
#10
Lingde Kong, Qinghua Ma, Kunlun Yu, Junming Cao, Linfeng Wang, Yong Shen
BACKGROUND Clinical adjacent-segment pathology (CASP) is an important problem after anterior cervical surgery. The purpose of this study was to predict prevalence of CASP and determine the possible risk factors for CASP after single-level anterior cervical discectomy and fusion surgery. MATERIAL AND METHODS We retrospectively reviewed a series of patients who underwent single-level cervical discectomy and fusion surgery (ACDF). Both basic and radiographic data of patients were collected. Life-table method and Kaplan-Meier analysis were used to calculate prevalence of CASP and disease-free survival rate...
October 25, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29063273/clinical-and-radiological-results-of-posterior-cervical-foraminotomy-at-two-or-three-levels-a-3-year-follow-up
#11
Dong Geun Lee, Choon Keun Park, Dong Chan Lee
BACKGROUND: Single-level unilateral posterior cervical foraminotomy is regarded as a safe method. However, the outcomes of posterior cervical foraminotomy performed on two or three levels are uncertain and debated. We aimed to analyze the long-term clinical and radiological outcomes of posterior cervical foraminotomy at two or three levels. METHODS: From September 2008 to December 2011, a total of 42 patients who underwent a posterior cervical foraminotomy at two or three levels and were followed for at least 3 years were analyzed with retrospective cohort study...
October 23, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29057356/anterior-cervical-spine-surgery-associated-complications-in-a-retrospective-case-control-study
#12
REVIEW
Anastasia Tasiou, Theofanis Giannis, Alexandros G Brotis, Ioannis Siasios, Iordanis Georgiadis, Haralampos Gatos, Eleni Tsianaka, Konstantinos Vagkopoulos, Konstantinos Paterakis, Kostas N Fountas
Anterior cervical spine procedures have been associated with satisfactory outcomes. However, the occurrence of troublesome complications, although uncommon, needs to be taken into consideration. The purpose of our study was to assess the actual incidence of anterior cervical spine procedure-associated complications and identify any predisposing factors. A total of 114 patients undergoing anterior cervical procedures over a 6-year period were included in our retrospective, case-control study. The diagnosis was cervical radiculopathy, and/or myelopathy due to degenerative disc disease, cervical spondylosis, or traumatic cervical spine injury...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29027895/changes-in-foraminal-area-with-anterior-decompression-versus-keyhole-foraminotomy-in-the-cervical-spine-a-biomechanical-investigation
#13
Jacqueline Nguyen, Bryant Chu, Calvin C Kuo, Jeremi M Leasure, Christopher Ames, Dimitriy Kondrashov
OBJECTIVE Anterior cervical discectomy and fusion (ACDF) with or without partial uncovertebral joint resection (UVR) and posterior keyhole foraminotomy are established operative procedures to treat cervical disc degeneration and radiculopathy. Studies have demonstrated reliable results with each procedure, but none have compared the change in neuroforaminal area between indirect and direct decompression techniques. The purpose of this study was to determine which cervical decompression method most consistently increases neuroforaminal area and how that area is affected by neck position...
October 13, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29024167/imaging-spinal-cord-atrophy-in-progressive-myelopathies-htlv-i-associated-neurological-disease-ham-tsp-and-multiple-sclerosis-ms
#14
Shila Azodi, Govind Nair, Yoshimi Enose-Akahata, Emily Charlip, Ashley Vellucci, Irene Cortese, Jenifer Dwyer, B Jeanne Billioux, Chevaz Thomas, Joan Ohayon, Daniel S Reich, Steven Jacobson
OBJECTIVE: Previous work measures spinal cord thinning in chronic progressive myelopathies, including human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and multiple sclerosis (MS). Quantitative measurements of spinal cord atrophy are important in fully characterizing these and other spinal cord diseases. We aimed to investigate patterns of spinal cord atrophy and correlations with clinical markers. METHODS: Spinal cord cross-sectional area was measured in individuals (24 healthy controls [HCs], 17 asymptomatic carriers of HTLV-1 (AC), 47 HAM/TSP, 74 relapsing-remitting MS [RRMS], 17 secondary progressive MS [SPMS], and 40 primary progressive MS [PPMS]) from C1 to T10...
October 10, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29022686/level-of-education-as-a-risk-factor-for-extensive-prevalence-of-cervical-intervertebral-disc-degenerative-changes-and-chronic-neck-pain
#15
Vedran Markotić, Damir Zubac, Miro Miljko, Goran Šimić, Amra Zalihić, Gojko Bogdan, Dorijan Radančević, Ana Dugandžić Šimić, Josip Mašković
OBJECTIVE: The aim of this study was to document the prevalence of degenerative intervertebral disc changes in the patients who previously reported symptoms of neck pain and to determine the influence of education level on degenerative intervertebral disc changes and subsequent chronic neck pain. METHODS: One hundred and twelve patients were randomly selected from the University Hospital in Mostar, Bosna and Herzegovina, (aged 48.5±12.7 years) and submitted to magnetic resonance imaging (MRI) of the cervical spine...
September 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/29019878/a-comparison-of-anterior-cervical-discectomy-and-fusion-combined-with-cervical-disc-arthroplasty-and-cervical-disc-arthroplasty-for-the-treatment-of-skip-level-cervical-degenerative-disc-disease-a-retrospective-study
#16
COMPARATIVE STUDY
Ting-Kui Wu, Bei-Yu Wang, Ming-Dan Deng, Ying Hong, Xin Rong, Hua Chen, Yang Meng, Hao Liu
Anterior cervical discectomy and fusion (ACDF) has been widely performed for the treatment of multilevel cervical degenerative disc disease (CDDD). In recent decades, cervical disc arthroplasty (CDA) and hybrid surgery (HS) have been developed to overcome the shortcomings of ACDF. Controversy still remains with regard to the optimal surgical procedure for skip-level CDDD.A total of 55 patients who received surgical treatment for skip-level CDDD in our department were reviewed. The patients were divided into the HS group (n = 29) and the CDA group (n = 26)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29019591/x-ray-dynamic-observation-of-cervical-degenerative-disease-induced-by-unbalanced-dynamic-and-static-forces-in-rats-1
#17
Hua Xie, Yongjing Huang, Luming Nong, Nanwei Xu, Gongming Gao, Dong Zhou
PURPOSE: To investigate dynamically the X-ray appearance of cervical degenerative disease induced by unbalanced dynamic and static forces in rats. METHODS: A total of 60 Sprague Dawley rats were randomized into test (n=45) and control (n=15) groups, which were randomly subdivided into the one-, three- and six-month post-operative groups. The test group included 10, 15 and 20 rats at the respective corresponding post-operative stage and the control group included five rats at each time-point...
September 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28991689/intraoperative-neuromonitoring-loss-in-abnormal-magnetic-resonance-imaging-signal-intensity-from-patients-with-cervical-compressive-myelopathy
#18
Xiangquan Lin, Chaoxiong Li, Qin Lin, Zhong Zheng
PURPOSE: Our objective of this study was to evaluate if cervical compressive myelopathy (CCM) patients with preoperative abnormal magnetic resonance imaging (MRI) might easily lead to intraoperative neuromonitoring (IONM) loss. METHOD: A consecutive series of 152 CCM patients who underwent cervical cord decompression were enrolled in this study between December 2013 and February 2017. All patients with abnormal MRI signal intensity were divided into 2 groups (group 1: T2-WIs hyperintensity; group 2: both T2-WIs hyperintensity and T1-WIs hypointensity)...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28986691/spinal-motion-preservation-surgery-indications-and-applications
#19
REVIEW
Ioannis D Gelalis, Dimitrios V Papadopoulos, Dionysios K Giannoulis, Andreas G Tsantes, Anastasios V Korompilias
Fusion is one of the most commonly performed spinal procedures, indicated for a wide range of spinal problems. Elimination of motion though results in accelerated degeneration of the adjacent level, known as adjacent level disease. Motion preservation surgical methods were developed in order to overcome this complication. These methods include total disc replacement, laminoplasty, interspinous implants and dynamic posterior stabilization systems. The initial enthusiasm about these methods was followed by certain concerns about their clinical usefulness and their results...
October 6, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28962908/should-long-segment-cervical-fusions-be-routinely-carried-into-the-thoracic-spine-multi-center-analysis
#20
Eeric Truumees, Devender Singh, Matthew J Geck, John K Stokes
BACKGROUND CONTEXT: While recommendations for caudal "end level" in posterior cervical reconstruction remain highly variable, the benefits of routine extension of posterior cervical fusions into the thoracic spine remain unclear. PURPOSE: Compare clinical and radiographic outcomes in patients in whom posterior fusions ended in the cervical spine versus those in whom the fusion was extended into the thoracic spine. STUDY DESIGN/SETTING: Multi-center retrospective analysis of prospectively followed patients...
September 26, 2017: Spine Journal: Official Journal of the North American Spine Society
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