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https://www.readbyqxmd.com/read/29278772/metric-learning-with-spectral-graph-convolutions-on-brain-connectivity-networks
#1
Sofia Ira Ktena, Sarah Parisot, Enzo Ferrante, Martin Rajchl, Matthew Lee, Ben Glocker, Daniel Rueckert
Graph representations are often used to model structured data at an individual or population level and have numerous applications in pattern recognition problems. In the field of neuroscience, where such representations are commonly used to model structural or functional connectivity between a set of brain regions, graphs have proven to be of great importance. This is mainly due to the capability of revealing patterns related to brain development and disease, which were previously unknown. Evaluating similarity between these brain connectivity networks in a manner that accounts for the graph structure and is tailored for a particular application is, however, non-trivial...
December 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/29204289/successful-treatment-of-tracheal-lymphoma-in-a-siamese-cat
#2
Laura Bataller, Alice Tamborini, Henry L'Eplattenier, Slavka Necova, Elise Robertson
Case summary: An 8-year-old female spayed Siamese indoor cat presented with a 3 week history of inspiratory dyspnoea, stridor and open-mouth breathing after exercise. Laryngoscopy, tracheoscopy, bronchoscopy and retroflexed nasopharyngoscopy were performed, and identified a multilobulated intraluminal mass within the trachea. Brush cytology was performed on the mass but was inconclusive in providing a definitive diagnosis. A CT scan of the neck failed to identify an obvious intraluminal mass and was negative to contrast uptake...
July 2017: JFMS Open Reports
https://www.readbyqxmd.com/read/29168058/analysis-of-siamese-crocodile-crocodylus-siamensis-eggshell-proteome
#3
Ivan Mikšík, Statis Paradis, Adam Eckhardt, David Sedmera
The proteins and pigment of the eggshell of the Siamese crocodile (Crocodylus siamensis) were analysed. For proteomic analysis, various decalcification methods were used when the two main surface layers were analyzed. These layers are important for antimicrobial defense of egg (particularly the cuticle). We found 58 proteins in both layers, of which 4 were specific for the cuticle and 26 for the palisade (honeycomb) layer. Substantial differences between proteins in the eggshell of crocodile and previously described birds' eggshells exist (both in terms of quality and quantity), however, the entire proteome of Crocodilians has not been described yet...
November 22, 2017: Protein Journal
https://www.readbyqxmd.com/read/29164679/novel-antioxidant-and-anti-inflammatory-peptides-from-the-siamese-crocodile-crocodylus-siamensis-hemoglobin-hydrolysate
#4
Jiraporn Lueangsakulthai, Santi Phosri, Tinnakorn Theansungnoen, Nisachon Jangpromma, Theeranan Temsiripong, John E Mckendrick, Watcharee Khunkitti, Sompong Klaynongsruang
Novel antioxidant and anti-inflammatory peptides were isolated from hydrolysates of Siamese crocodile (Crocodylus siamensis) hemoglobin. Crocodylus siamensis hemoglobin hydrolysates (CHHs) were obtained by pepsin digestion at different incubation times (2, 4, 6 and 8 H) at 37 °C and subjected to antioxidant and anti-inflammatory activity assessment. CHH obtained by 2-H hydrolysis (2H-CHH) showed the highest anti-inflammatory activity with respect to decreasing nitric oxide (NO) production, while the strongest antioxidant activity was found for 6-H hydrolysis (6H-CHH) against nitric oxide radicals...
November 22, 2017: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/29024431/the-cytoarchitecture-of-the-telencephalon-of-betta-splendens-regan-1910-perciformes-anabantoidei-with-a-stereological-approach-to-the-supracommissural-and-postcommissural-nuclei
#5
Ângelo Cássio Magalhães Horn, Alberto A Rasia-Filho
Teleostean fish brains are useful models to study cellular and functional specializations along the phylogenesis. The Betta splendens Regan 1910 (Siamese fighting fish; Perciformes:Anabantoidei) is known for its aggressive display, courtship behavior, nest building, and offspring care. Here, we present novel and detailed data about the cytoarchitecture of the olfactory bulb and the telencephalic hemispheres of this fish. The hematoxylin-eosin and Nissl techniques served to identify brain nuclei (n = 19 males and n = 21 females) and for the stereological evaluation of the numerical density of cells and the proportion of neurons and glial cells in the ventral telencephalon supracommissural (Vs) and postcommissural (Vp) nuclei of adult males and females...
October 10, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28955476/periaortic-lymphoma-in-a-cat
#6
Laura Bree, Chiara Bergamino, Ronan Mullins, Pamela Kelly, Robert Shiel
CASE SUMMARY: A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar grade II/VI systolic heart murmur. Neurological examination revealed hindlimb ataxia, severe atrophy of the hindlimb musculature, intermittent hindlimb proprioceptive deficits and normoreflexia...
July 2017: JFMS Open Reports
https://www.readbyqxmd.com/read/28953895/high-genetic-diversity-and-demographic-history-of-captive-siamese-and-saltwater-crocodiles-suggest-the-first-step-toward-the-establishment-of-a-breeding-and-reintroduction-program-in-thailand
#7
Sorravis Lapbenjakul, Watcharaporn Thapana, Panupon Twilprawat, Narongrit Muangmai, Thiti Kanchanaketu, Yosapong Temsiripong, Sasimanas Unajak, Surin Peyachoknagul, Kornsorn Srikulnath
The Siamese crocodile (Crocodylus siamensis) and Saltwater crocodile (C. porosus) are two of the most endangered animals in Thailand. Their numbers have been reduced severely by hunting and habitat fragmentation. A reintroduction plan involving captive-bred populations that are used commercially is important and necessary as a conservation strategy to aid in the recovery of wild populations. Here, the genetic diversity and population structure of 69 individual crocodiles, mostly members of captive populations, were analyzed using both mitochondrial D-loop DNA and microsatellite markers...
2017: PloS One
https://www.readbyqxmd.com/read/28951689/awareness-and-knowledge-of-oral-cancer-among-siamese-ethnic-group-in-tumpat-kelantan
#8
Nur Karyatee Kassim, Munirah Mohd Adnan, Chew Wei Wern, Lim Zheng Ru, Muhammad Hafiz Hanafi, Azizah Yusoff
INTRODUCTION: Oral cancer is a life-threatening disease. Lack of public awareness is a potent barrier for the early detection of oral cancer, especially for high-risk populations. OBJECTIVE: This study aimed to determine the awareness and knowledge of the signs, symptoms and risk factors of oral cancer among a Siamese ethnic group in Tumpat, Kelantan. METHODS: A cross-sectional study was conducted, using a guided questionnaire on sociodemography, habits, awareness and knowledge of the signs, symptoms and risk factors of oral cancer...
August 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28886182/toxoplasma-gondii-seroprevalence-varies-by-cat-breed
#9
Kärt Must, Marjo K Hytönen, Toomas Orro, Hannes Lohi, Pikka Jokelainen
Toxoplasma gondii is a widespread zoonotic parasite that is relevant for veterinary and public health. The domestic cat, the definitive host species with the largest worldwide population, has become evolutionarily and epidemiologically the most important host of T. gondii. The outcome of T. gondii infection is influenced by congenital and acquired host characteristics. We detected differences in T. gondii seroprevalence by cat breed in our previous studies. The aims of this study were to estimate T. gondii seroprevalence in selected domestic cat breeds, and to evaluate whether being of a certain breed is associated with T...
2017: PloS One
https://www.readbyqxmd.com/read/28873495/-defect-coverage-of-the-hand-using-a-rare-siamese-combined-flap
#10
Itai Pasternak, Urs Hug, Eva Meia Rüegg, Elmar Fritsche
We report 2 cases of extensive soft tissue defects simultaneously affecting the palm and dorsum of the hand. The defect was covered with a Siamese flap combination consisting of a free, distally extended lateral upper arm flap with microvascular anastomosis, and a posterior interosseous artery flap. We discuss possible indications, the operative technique and advantages versus disadvantages of this rarely applied flap combination.
October 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28680126/multiple-cues-produced-by-a-robotic-fish-modulate-aggressive-behaviour-in-siamese-fighting-fishes
#11
Donato Romano, Giovanni Benelli, Elisa Donati, Damiano Remorini, Angelo Canale, Cesare Stefanini
The use of robotics to establish social interactions between animals and robots, represents an elegant and innovative method to investigate animal behaviour. However, robots are still underused to investigate high complex and flexible behaviours, such as aggression. Here, Betta splendens was tested as model system to shed light on the effect of a robotic fish eliciting aggression. We evaluated how multiple signal systems, including a light stimulus, affect aggressive responses in B. splendens. Furthermore, we conducted experiments to estimate if aggressive responses were triggered by the biomimetic shape of fish replica, or whether any intruder object was effective as well...
July 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28612380/breed-coat-color-and-hair-length-as-risk-factors-for-hyperthyroidism-in-cats
#12
V J Crossley, A Debnath, Y M Chang, R C Fowkes, J Elliott, H M Syme
BACKGROUND: Hyperthyroidism is very common in older cats, but the etiopathogenesis is poorly understood. Decreased risk of hyperthyroidism has been reported in certain colorpoint breeds, and this observation previously has been hypothesized to result from relatively greater tyrosine availability for thyroid hormone production because of limited ability to convert tyrosine to melanin pigment. However, studies investigating a potential link between coat pigmentation and risk of hyperthyroidism are limited...
July 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28585658/-cystinuria-caused-by-a-slc7a9-missense-mutation-in-siamese-crossbred-littermates-in-germany
#13
Stephanie Hilton, Keijiro Mizukami, Urs Giger
Cystinuria is caused by defective proximal renal tubular reabsorption of the amino acids cystine, ornithine, lysine, and arginine (COLA). The low solubility of cystine in mildly acidic urine may lead to the formation of urinary cystine crystals and uroliths. Much progress has been made recently in the diagnosis and understanding of cystinuria in companion animals. In cats, cystinuria affects equally both genders independent of neutering status and, despite being rare, already more cystinuria-causing mutations have been detected in cats compared to dogs...
August 11, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28364643/a-multi-resolution-approach-for-spinal-metastasis-detection-using-deep-siamese-neural-networks
#14
Juan Wang, Zhiyuan Fang, Ning Lang, Huishu Yuan, Min-Ying Su, Pierre Baldi
Spinal metastasis, a metastatic cancer of the spine, is the most common malignant disease in the spine. In this study, we investigate the feasibility of automated spinal metastasis detection in magnetic resonance imaging (MRI) by using deep learning methods. To accommodate the large variability in metastatic lesion sizes, we develop a Siamese deep neural network approach comprising three identical subnetworks for multi-resolution analysis and detection of spinal metastasis. At each location of interest, three image patches at three different resolutions are extracted and used as the input to the networks...
May 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28344527/reverse-radial-forearm-flap-to-provide-arterial-inflow-to-a-toe-transfer
#15
Joohak Kim, Alfred P Yoon, Neil F Jones
Background: Toe-to-thumb transfer has become the gold standard for thumb reconstruction, but in badly mutilated hands, additional soft tissue coverage may be required or a suitable recipient artery may not be available. There are only 3 case reports describing the successful use of a reverse radial forearm flap for coverage of a soft tissue defect around the thumb as well as providing arterial inflow for a toe transfer, performed either simultaneously or secondarily. Methods: A single surgeon's experience of all toe-to-hand transfers performed in conjunction with a reverse radial forearm flap between 1995 and 2014 was reviewed, including patient demographics, type of toe transfer and vascular pedicle, whether immediate or secondary, follow-up, and complications...
March 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28259903/siamese-crocodile-bile-induces-apoptosis-in-nci-h1299-human-non-small-cell-lung-cancer-cells-via-a-mitochondria-mediated-intrinsic-pathway-and-inhibits-tumorigenesis
#16
Ling Tian, Yi-Tao Deng, Xin Dong, Jia-Yi Fan, Hua-Liang Li, Yu-Mei Ding, Wei-Xi Peng, Qing-Xi Chen, Dong-Yan Shen
Non-small-cell lung cancer (NSCLC) is a widespread and particularly aggressive form of cancer. Patients with NSCLC and early metastases typically have poor prognosis, highlighting the critical need for additional drugs to improve disease outcome following surgical resection. The present study aimed to determine if Siamese crocodile bile (SCB) had an anti‑cancer effect on NCI‑H1299 human NSCLC cells. The inhibitory mechanism of SCB was examined in cell culture and nude mice. In vitro experimental results revealed that SCB inhibited the proliferation and colony‑forming ability of NCI‑H1299 cells by arresting cell cycle and inducing apoptosis...
April 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28248337/separating-the-siamese-twins-using-a-%C3%AF-shifted-sagnac-interferometer-to-control-the-relative-weight-influence-of-circular-and-linear-birefringence-on-the-loop-transmission-facilitating-their-measurement
#17
Eric Want-Gauthier, Ilya Golub
We demonstrate a novel method to measure circular birefringence (CB) and linear birefringence (LB) present simultaneously in the device under study. By using a π-shifted Sagnac interferometer, the scheme eliminates the dependence on incoming polarization and on the orientation angle of the linear birefringence. Moreover, due to different handedness symmetry/response of CB and LB to counter-propagating waves, the technique allows us to control the relative influence of the two birefringences leading to a requirement of only two measurements to determine both of them...
March 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28237550/of-fish-and-mirrors-fluoxetine-disrupts-aggression-and-learning-for-social-rewards
#18
Benjamin R Eisenreich, Susan Greene, Allen Szalda-Petree
Aggressive signaling is a key social behavior of male Siamese fighting fish (Betta splendens). Successfully establishing a territory and defending it from intruders has direct fitness effects, making Betta splendens a prime model for studies examining the biological underpinnings of aggressive behavior. Current research has outlined serotonin transporter pathways as one key component for the engagement and coordination of aggressive behavior in Betta splendens. Using the selective serotonin reuptake inhibitor fluoxetine, we examined the impact of 10μmol exposures on associative learning and aggression between mirror and conspecific social reinforcers...
February 22, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28236686/prozac-impacts-lateralization-of-aggression-in-male-siamese-fighting-fish
#19
Maryam HedayatiRad, Mohammad Ali Nematollahi, Mohammad Navid Forsatkar, Culum Brown
Previous studies have shown that Siamese fighting fish, Betta splendens, preferentially use right-eye during the aggressive displays. However, administration of antidepressant drugs may disrupt eye-use preference in association with a reduction in aggression; a phenomena that has not been explored in fish. The objective of the current study was to examine the effects of exposure to the antidepressant drug, fluoxetine, on lateralization in eye-use during aggressive displays in male Siamese fighting fish. Baseline aggression and lateralization in eye use of thirty fish were assessed toward live conspecifics, following which experimental subjects (n=15) were then exposed to fluoxetine (540ng/L) in a static renewal water system...
June 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28165885/why-do-plants-need-so-many-cyclin-dependent-kinase-inhibitors
#20
Narender Kumar, John C Larkin
Cell cycle regulation is fundamental to growth and development, and Cyclin-Dependent Kinase Inhibitors (CKIs) are major negative regulators of the cell cycle. Plant genomes encode substantially more CKIs than metazoan or fungal genomes. Plant CKIs fall into 2 distinct families, KIP-RELATED PROTEINS (KRPs) and SIAMESE-RELATED proteins (SMRs). SMRs can inhibit both S-phase and M-phase CDK complexes in vitro and are transcribed throughout the cell cycle, yet SMRs do not inhibit DNA replication in vivo. This suggests that SMRs must be activated post transcriptionally after the start of S-phase, but the mechanism of this hypothesized activation is unknown...
February 2017: Plant Signaling & Behavior
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