keyword
MENU ▼
Read by QxMD icon Read
search

Cognitive activity

keyword
https://www.readbyqxmd.com/read/29909256/task-induced-gamma-band-effect-in-type-ii-focal-cortical-dysplasia-an-exploratory-study
#1
Sabrine Souci, Mathilde Petton, Julien Jung, Pierre Bourdillon, Romain Bouet, Aurélie Richard-Mornas, Nathalie Streichenberger, Hélène Catenoix, Alexandra Montavont, Jean Isnard, Marc Guenot, Philippe Kahane, Jean-Philippe Lachaux, Sylvain Rheims
OBJECTIVE: Few data are available about the functionality of type II focal cortical dysplasia (FCD). Identification of high-frequency activities (HFAs) induced by cognitive tasks has been proposed as an additional way to map cognitive functions in patients undergoing presurgical evaluation using stereoelectroencephalography (SEEG). However, the repetitive subcontinuous spiking pattern which characterizes type II FCD might limit the reliability of this approach, and its feasibility in these patients remains to be evaluated...
June 14, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29909181/stress-related-deficits-of-older-adults-spatial-working-memory-an-eeg-investigation-of-occipital-alpha-and-frontal-midline-theta-activities
#2
Amanda C Marshall, Nicholas Cooper, Livia Rosu, Steffan Kennett
Studies highlight cumulative life stress as a significant predictor of accelerated cognitive aging. This study paired electrophysiological with behavioral measures to explore how cumulative stress affects attentional and maintenance processes underpinning working memory retention. We collected electroencephalographic recordings from 60 individuals (30 older, 30 younger) reporting high or low levels of cumulative stress during the performance of a spatial Sternberg task. We measured mid-occipital alpha (8-12 Hz) and frontal-midline theta (4-6 Hz) as indicators of attentional and maintenance processes...
May 29, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29909179/apoe-%C3%AE%C2%B54-status-in-healthy-older-african-americans-is-associated-with-deficits-in-pattern-separation-and-hippocampal-hyperactivation
#3
Neha Sinha, Chelsie N Berg, Nicholas J Tustison, Ashlee Shaw, Diane Hill, Michael A Yassa, Mark A Gluck
African Americans are 1.4 times more likely than European Americans to carry the apolipoprotein E (APOE) ε4 allele, a risk factor for Alzheimer's disease (AD). However, little is known about the neural correlates of cognitive function in older African Americans and how they relate to genetic risk for AD. In particular, no past study on African Americans has examined the effect of APOE ε4 status on pattern separation-mnemonic discrimination performance and its corresponding neural computations in the hippocampus...
May 26, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29909076/resting-state-brain-activity-changes-associated-with-tardive-dyskinesia-in-patients-with-schizophrenia-fractional-amplitude-of-low-frequency-fluctuation-decreased-in-the-occipital-lobe
#4
Ping Zhang, Yanli Li, Fengmei Fan, Chiang-Shan R Li, Xingguang Luo, Fude Yang, Yin Yao, Yunlong Tan
We explored resting-state brain activity and its potential links to clinical parameters in schizophrenic patients with tardive dyskinesia (TD) using fractional amplitude of low frequency fluctuations(fALFF). Resting-state functional magnetic resonance imaging data were acquired from 32 schizophrenic patients with TD (TD group), 31 without TD (NTD group), and 32 healthy controls (HC group). Clinical parameters including psychopathological symptoms, severity of TD, and cognitive function were assessed using the Positive and Negative Syndrome Scale, Abnormal Involuntary Movement Scale (AIMS), and Repeatable Battery for the Assessment of Neuropsychological Status, respectively...
June 14, 2018: Neuroscience
https://www.readbyqxmd.com/read/29909026/towards-using-fnirs-recordings-of-mental-arithmetic-for-the-detection-of-residual-cognitive-activity-in-patients-with-disorders-of-consciousness-doc
#5
Eva-Maria Kurz, Guilherme Wood, Silvia Erika Kober, Walter Schippinger, Gerald Pichler, Gernot Müller-Putz, Günther Bauernfeind
BACKGROUND: Recently, fNIRS has been proposed as a promising approach for awareness detection, and a possible method to establish basic communication in patients with disorders of consciousness (DOC). AIM: Using fNIRS, the present study evaluated the applicability of auditory presented mental-arithmetic tasks in this respect. METHODS: We investigated the applicability of active attention to serial subtractions for awareness detection in ten healthy controls (HC, 21-32 y/o), by comparing the measured patterns to patterns induced by self-performance of the same task...
June 14, 2018: Brain and Cognition
https://www.readbyqxmd.com/read/29908972/bidirectional-relationships-between-sleep-and-amyloid-beta-in-the-hippocampus
#6
Julien Dufort-Gervais, Valérie Mongrain, Jonathan Brouillette
Alzheimer's disease (AD) is a debilitating neurodegenerative disease characterized by progressive hippocampal-dependent explicit memory deficits that begin at the onset of the illness. An early hallmark of AD is the accumulation of amyloid-beta (Aß) proteins in brain structures involved in encoding and consolidation of memory, like the hippocampus and prefrontal cortex. Aß neurotoxicity is known to induce synaptic dysfunctions and neuronal death leading to cognitive decline. Another recurrent event observed in AD is sleep disturbances...
June 14, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29908971/why-are-maternally-separated-females-inflexible-brain-activity-pattern-of-cox-and-c-fos
#7
María Banqueri, Marta Méndez, Jorge L Arias
Subjects' early life events will affect them later in life. When these events are stressful, such as child abuse in humans or repeated maternal separation in rodents, subjects can show some behavioral and brain alterations. This study used young adult female Wistar rats that were maternally raised (AFR), maternally separated from post-natal day (PND) 1 to PND10 (MS10), or maternally separated from PND1 to PND21 (MS21), in order to assess the effects of maternal separation (MS) on spatial learning and memory, as well as cognitive flexibility, using the Morris Water Maze (MWM)...
June 14, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29908937/sparking-interest-in-restaurant-dishes-cognitive-and-affective-processes-underlying-dish-design-and-ecological-origin-an-fmri-study
#8
Francisco Muñoz-Leiva, Diego Gómez-Carmona
The objective of the current paper is to verify to what extent the presentation of a restaurant dish and the origin of its food provoke reactions in the consumer's brain during the visualization and the decision-making process, from an exploratory approach. The two independent variables singled out for study were whether the presentation was well or poorly presented and if the ingredients were ecological or non-ecological. The results applying the functional magnetic resonance image (fMRI) methodology reveal that well-presented dishes activate areas in the brain linked to the network of emotions indicating that the visualization in restaurant menus is not a purely cognitive and self-reflexive process but retains a strong affective component...
June 14, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29908766/beyond-health-care-volunteer-work-social-participation-and-late-life-general-cognitive-status-in-taiwan
#9
Chi Chiao
SIGNIFICANCE: In addition to the complexity associated with health care coverage and its utilization by older people, I hypothesize that social engagement promotes a better later-life general cognitive status beyond health care availability as is provided by Taiwan's National Health Insurance (NHI) system. The present study thus explores whether social engagement, specifically social participation and volunteer work, is independently associated with later-life general cognitive status after adjusting for health service utilization among older Taiwanese via the NHI system...
June 7, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29908472/cognitive-bias-modification-as-an-add-on-treatment-in-clinical-depression-results-from-a-placebo-controlled-single-blinded-randomized-control-trial
#10
Janna N Vrijsen, Verena S Fischer, Bernhard W Müller, Norbert Scherbaum, Eni S Becker, Mike Rinck, Indira Tendolkar
BACKGROUND: Only 60% of depressed patients respond sufficiently to treatment, so there is a dire need for novel approaches to improve treatment effects. Cognitive Bias Modification (CBM) may be an effective and easily implemented computerized add-on to treatment-as-usual. Therefore, we investigated the effects of a positivity-attention training and a positivity-approach training compared to control trainings. METHODS: In a blinded randomized-controlled design, 139 depressed inpatients received either the CBM Attention Dot-Probe Training (DPT) or the CBM Approach-Avoidance Training (AAT), next to treatment as usual...
June 6, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29908350/exome-sequencing-identified-a-de-novo-mutation-of-pura-gene-in-a-patient-with-familial-xp22-31-microduplication
#11
Ying Qiao, Hani Bagheri, Flamingo Tang, Chansonette Badduke, Sally Martell, Suzanne M E Lewis, Wendy Robinson, Mary B Connolly, Laura Arbour, Evica Rajcan-Separovic
The clinical significance of Xp22.31 microduplication is controversial as it is reported in subjects with developmental delay (DD), their unaffected relatives and unrelated controls. We performed multifaceted studies in a family of a boy with hypotonia, dysmorphic features and DD who carried a 600 Kb Xp22.31 microduplication (7515787-8123310bp, hg19) containing two genes, VCX and PNPLA4. The duplication was transmitted from his cognitively normal maternal grandfather. We found no evidence of the duplication causing the proband's DD and congenital anomalies based on unaltered expression of PNPLA4 in the proband and his mother in comparison to controls and preferential activation of the paternal chromosome X with Xp22...
June 13, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29908300/acute-and-chronic-escitalopram-alter-eeg-gamma-oscillations-differently-relevance-to-therapeutic-effects
#12
Noémi Papp, Szilvia Vas, Emese Bogáthy, Zita Kátai, Diána Kostyalik, György Bagdy
Brain oscillations in the gamma frequency band of the electroencephalogram (EEG) have been implicated in several sensory and cognitive processes, and have also been associated with numerous neuropsychiatric disorders, including depression. The widely prescribed selective serotonin reuptake inhibitors (SSRIs), similarly to other antidepressants, are known to produce markedly different effects on sleep and behavioral measures with acute and chronic administration. Although there are studies examining the acute effect of escitalopram on slower (<30 Hz) oscillations, we hardly could find any data about the effect of the drug on higher-frequency EEG oscillations (>30 Hz) in different sleep-wake stages, particularly comparing the acute and chronic effects of the drug concerning gamma oscillations...
June 13, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29908256/the-protective-effect-of-%C3%AE-lipoic-acid-against-bisphenol-a-induced-neurobehavioral-toxicity
#13
Jasim Khan, Shikha Salhotra, Shahzad Ahmad, Shikha Sharma, Sayed Aliul Hasan Abdi, Basu Dev Banerjee, Suhel Parvez, Sarika Gupta, Sheikh Raisuddin
Bisphenol A (BPA), a well-known xenoestrogen, is ubiquitously utilized in manufacturing of polycarbonated plastics. Convincing evidence suggests that BPA induces neurotoxicity and certain behavioral deficits. α-Lipoic acid (ALA) supplementation has shown protective effect against heart and liver diseases, diabetes, and neurological debility associated with aging. We studied the neuromodulatory effect of ALA against neurotoxicity of BPA in vitro in C8-D1A mouse astrocyte cell line and in vivo in C57BL/6J male mice...
June 13, 2018: Neurochemistry International
https://www.readbyqxmd.com/read/29908165/consequences-of-tuning-network-function-by-tonic-and-phasic-locus-coeruleus-output-and-stress-regulating-detection-and-discrimination-of-peripheral-stimuli
#14
David M Devilbiss
Flexible and adaptive behaviors have evolved with increasing complexity and numbers of neuromodulator systems. The neuromodulatory locus coeruleus-norepinephrine (LC-NE) system is central to regulating cognitive function in a behaviorally-relevant and arousal-dependent manner. Through its nearly ubiquitous efferent projections, the LC-NE system acts to modulate neuron function on a cell-by-cell basis and exert a spectrum of actions across different brain regions to optimize target circuit function. As LC neuron activity, NE signaling, and arousal level increases, cognitive performance improves over an inverted-U shaped curve...
June 13, 2018: Brain Research
https://www.readbyqxmd.com/read/29907977/melatonin-induces-mechanisms-of-brain-resilience-against-neurodegeneration
#15
Rubén Corpas, Christian Griñán-Ferré, Verónica Palomera-Ávalos, David Porquet, Pablo García de Frutos, Silvia M Franciscato Cozzolino, Eduard Rodríguez-Farré, Mercè Pallàs, Coral Sanfeliu, Bárbara R Cardoso
Melatonin is an endogenous pleiotropic molecule which orchestrates regulatory functions and protective capacity against age-related ailments. The increase in circulating levels of melatonin through dietary supplements intensifies its health benefits. Investigations in animal models have shown that melatonin protects against Alzheimer's disease (AD)-like pathology, although clinical studies have not been conclusive. We hypothesized that melatonin induces changes in the brain that prevent or attenuate AD by increasing resilience...
June 15, 2018: Journal of Pineal Research
https://www.readbyqxmd.com/read/29907754/nano-particle-mediated-inhibition-of-parkinson-s-disease-using-computational-biology-approach
#16
Aman Chandra Kaushik, Shiv Bharadwaj, Sanjay Kumar, Dong-Qing Wei
Parkinson's disease (PD) arises as neurodegenerative disorder and characterized by progressive deterioration of motor functions due to forfeiture of dopamine-releasing neurons. During PD, neurons at stake loss their functionality that results into cognition impairment and forgetfulness, commonly called as dementia. Recently, nanoparticles (NPs) have been reported for easy drug delivery through blood-brain barrier (BBB) into the central nervous system (CNS) against the conventional drug delivery systems. However, present study attempted to elucidate the α-synuclein activity, a major factor casing PD, in presence of its inhibitor cerium oxide (CeO2 ) nanoparticle via computational biology approach...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907639/t-type-calcium-channels-in-the-orbitofrontal-cortex-mediate-sensory-integration-as-measured-using-a-spontaneous-oddity-task-in-rats
#17
Wendie N Marks, Madeline E Parker, Nadine K Zabder, Quentin Greba, Terrance P Snutch, John G Howland
The roles of low-voltage-activated (T-type) calcium channels in brain diseases have been studied extensively. Less is known regarding the involvement of T-type channels in cognition and behavior. Sensory integration (SI) is a cognitive process whereby the brain uses unimodal or multimodal sensory features to create a comprehensive representation of the environment. The multisensory object oddity (MSO) task assesses SI using combinations of sensory features of objects, either in the same or different sensory modalities...
July 2018: Learning & Memory
https://www.readbyqxmd.com/read/29907498/implicit-motivation-improves-executive-functions-of-older-adults
#18
Shira Cohen-Zimerman, Ran R Hassin
It is widely accepted that while controlled processes (e.g., working memory and executive functions) decline with age, implicit (automatic) processes are not affected by age. In this paper we challenge this view by arguing that high-level automatic processes (e.g., recruiting motivation) decline with age, and that this decline plays an unappreciated role in cognitive aging. Specifically, we hypothesized that due to their decline, automatic motivational processes are less likely to be spontaneously activated in old age; thus, implicit external activation of them should have stronger effects on older (vs...
June 12, 2018: Consciousness and Cognition
https://www.readbyqxmd.com/read/29907336/functioning-in-patients-with-schizophrenia-a-multicentre-study-evaluating-the-clinical-perspective
#19
Maite Barrios, Juana Gómez-Benito, Oscar Pino, Emilio Rojo, Georgina Guilera
Using the WHO International Classification of Functioning, Disability and Health (ICF) as a frame of reference, this study identifies the most common problems of functioning and the environmental factors that are experienced by patients with schizophrenia. An empirical cross-sectional multicentre study was conducted. Data were collected using a case record form, rated by health professionals, that contained 133 ICF categories and which also gathered clinical and sociodemographic information. A total of 127 patients with schizophrenia participated...
June 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29907246/cognitive-impairment-and-the-association-between-frailty-and-functional-deficits-are-linked-to-abdominal-obesity-in-the-elderly
#20
Assaf Buch, Eli Carmeli, Gabi Shefer, Lital Keinan-Boker, Yitshal Berner, Yonit Marcus, Rebecca Goldsmith, Naftali Stern
OBJECTIVE: To evaluate whether specific obesity phenotypes in community-dwelling elderly: (a) affect differently the relationship between frailty and functional impairment and (b) are related to cognitive impairment. STUDY DESIGN: A post-hoc cross-sectional analysis of the last Israeli national health and nutrition survey of the elderly (≥ 65 yrs.; n = 1619). MAIN OUTCOME MEASURES: We implemented a previously validated frailty model based on frailty-related variables that were obtained in the survey...
August 2018: Maturitas
keyword
keyword
81086
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"