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https://www.readbyqxmd.com/read/29150901/expression-of-the-clock-gene-rev-erb%C3%AE-in-the-brain-controls-the-circadian-organization-of-food-intake-and-locomotor-activity-but-not-daily-variations-of-energy-metabolism
#1
Satish Sen, Stéphanie Dumont, Dominique Sage-Ciocca, Sophie Reibel, Paul de Goede, Andries Kalsbeek, Etienne Challet
The nuclear receptor REV-ERBα is part of the molecular clock mechanism and thought to be involved in a variety of biological processes within metabolically active peripheral tissues as well. To investigate whether Rev-erbα (also known as Nr1d1) in the brain plays a role in the daily variations of energy metabolism, feeding behaviour and the sleep-wake cycle, we studied mice with global (GKO) or brain (BKO) deletion of Rev-erbα. Mice were studied both in a light-dark cycle and constant darkness, and 24-h variations of Respiratory quotient (RQ) and energy expenditure, as well as the temporal patterns of rest-activity and feeding behavior were recorded...
November 18, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29147496/markov-chain-based-acute-effect-estimation-of-air-pollution-on-elder-asthma-hospitalization
#2
Li Luo, Fengyi Zhang, Wei Zhang, Lin Sun, Chunyang Li, Debin Huang, Gao Han, Bin Wang
Background: Asthma caused substantial economic and health care burden and is susceptible to air pollution. Particularly, when it comes to elder asthma patient (older than 65), the phenomenon is more significant. The aim of this study is to investigate the Markov-based acute effects of air pollution on elder asthma hospitalizations, in forms of transition probabilities. Methods: A retrospective, population-based study design was used to assess temporal patterns in hospitalizations for asthma in a region of Sichuan province, China...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29146923/incidence-and-mortality-of-kidney-cancer-temporal-patterns-and-global-trends-in-39-countries
#3
Martin C S Wong, William B Goggins, Benjamin H K Yip, Franklin D H Fung, Colette Leung, Yuan Fang, Samuel Y S Wong, C F Ng
We tested the hypotheses that kidney cancer incidence was increasing globally whilst its mortality was reducing; and its incidence was positively correlated with country-specific socioeconomic development. The incidence and mortality figures of each country were projected to 2030. Data on age-standardized incidence/mortality rates were retrieved from the GLOBOCAN in 2012. Temporal patterns were examined for 39 countries from the Cancer Incidence in Five Continents volumes I-X and other national registries. We evaluated the correlation between the incidence/mortality rates and Human Development Index (HDI)/Gross Domestic Product (GDP])...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29146163/a-comparative-biomechanical-study-of-femoral-cortical-suspension-devices-for-soft-tissue-anterior-cruciate-ligament-reconstruction-adjustable-length-loop-versus-fixed-length-loop
#4
Moon Jong Chang, Tae Soo Bae, Young-Wan Moon, Jin Hwan Ahn, Joon Ho Wang
PURPOSE: To determine whether there are differences between adjustable-length loop and fixed-length loop devices in terms of the amount of displacement, temporal pattern of displacement, and ultimate failure load when tested using 4,500 cycles of sinusoidal loading with high loads (100-400 N). METHODS: Two cortical suspension devices with a fixed- or adjustable-length loop were tested. For our comparisons, a 20-mm fixed-length loop device and a fixed-length loop device with the same loop length were used...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29145003/the-importance-of-saprinus-semistriatus-coleoptera-histeridae-for-estimating-the-minimum-post-mortem-interval
#5
I Szelecz, N Feddern, C V W Seppey, J Amendt, E A D Mitchell
In forensic science, the use of entomological evidence to estimate the minimum post-mortem interval can be crucial. However, not all cadaver-visiting insects are equally useful. Our focus is on the histerid beetle Saprinus semistriatus (Scriba 1790) (Histeridae; Coleoptera). Histeridae are common predators that feed mainly on dipteran larvae on carrion and dung. We review 23 publications mentioning this species and provide new experimental data on its temporal pattern beneath and on hanging pig cadavers. In a field experiment near Neuchâtel, Switzerland, we recorded the abundance of S...
November 10, 2017: Legal Medicine
https://www.readbyqxmd.com/read/29143143/soil-respiration-patterns-and-rates-at-three-taiwanese-forest-plantations-dependence-on-elevation-temperature-precipitation-and-litterfall
#6
Yu-Hsuan Huang, Chih-Yu Hung, I-Rhy Lin, Tomonori Kume, Oleg V Menyailo, Chih-Hsin Cheng
BACKGROUND: Soil respiration contributes to a large quantity of carbon emissions in the forest ecosystem. In this study, the soil respiration rates at three Taiwanese forest plantations (two lowland and one mid-elevation) were investigated. We aimed to determine how soil respiration varies between lowland and mid-elevation forest plantations and identify the relative importance of biotic and abiotic factors affecting soil respiration. RESULTS: The results showed that the temporal patterns of soil respiration rates were mainly influenced by soil temperature and soil water content, and a combined soil temperature and soil water content model explained 54-80% of the variation...
November 15, 2017: Botanical Studies (Taipei, Taiwan)
https://www.readbyqxmd.com/read/29141566/perioperative-levels-of-adiponectin-and-oxidative-stress-in-patients-undergoing-laparoscopic-abdominal-surgery-for-cancer
#7
Cosimo Chelazzi, Gianluca Villa, Paola Mancinelli, Matteo Becatti, Maria Boddi, Mirella Coppo, Stefano Romagnoli
BACKGROUND: Low circulating levels of adiponectin are associated with the occurrence of infection after surgery in patients with cancer. Data are lacking on whether surgical stress is associated with a reduction in circulating levels of adiponectin. Furthermore, the relationships between oxidative stress and postoperative complications have not been investigated. OBJECTIVE: The aim of this study was to evaluate the pre-, intra-, and postoperative levels of adiponectin in patients who underwent major abdominal surgery for malignancy and their association with postoperative complications...
November 14, 2017: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/29139050/modeling-mesoscopic-cortical-dynamics-using-a-mean-field-model-of-conductance-based-networks-of-adaptive-exponential-integrate-and-fire-neurons
#8
Yann Zerlaut, Sandrine Chemla, Frederic Chavane, Alain Destexhe
Voltage-sensitive dye imaging (VSDi) has revealed fundamental properties of neocortical processing at macroscopic scales. Since for each pixel VSDi signals report the average membrane potential over hundreds of neurons, it seems natural to use a mean-field formalism to model such signals. Here, we present a mean-field model of networks of Adaptive Exponential (AdEx) integrate-and-fire neurons, with conductance-based synaptic interactions. We study a network of regular-spiking (RS) excitatory neurons and fast-spiking (FS) inhibitory neurons...
November 15, 2017: Journal of Computational Neuroscience
https://www.readbyqxmd.com/read/29138015/anti-phase-synchronization-of-influenza-a-h1n1-and-a-h3n2-in-hong-kong-and-countries-in-the-north-temperate-zone
#9
Alice P Y Chiu, Qianying Lin, Edwin Yiu Nam Tang, Daihai He
OBJECTIVES: Influenza affects 10% of the global population annually. Hong Kong is a subtropical city close to the North Temperate Zone (NTZ). Its influenza-associated mortality rates were 27.53, 79.55, 36.94, 48.72 per one million person-years in 2014, 2015, 2016 and January to July 2017 respectively. Our study aims at exploring the temporal patterns of influenza A subtypes both in Hong Kong and the NTZ. METHOD: Weekly reported cases of Influenza A/H1N1 and A/H3N2 from January 2010 to July 2017 were downloaded from the Centre for Health Protection in HK and the FluNet provided by the World Health Organization...
November 11, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29136658/community-ecology-in-3d-tensor-decomposition-reveals-spatio-temporal-dynamics-of-large-ecological-communities
#10
Romain Frelat, Martin Lindegren, Tim Spaanheden Denker, Jens Floeter, Heino O Fock, Camilla Sguotti, Moritz Stäbler, Saskia A Otto, Christian Möllmann
Understanding spatio-temporal dynamics of biotic communities containing large numbers of species is crucial to guide ecosystem management and conservation efforts. However, traditional approaches usually focus on studying community dynamics either in space or in time, often failing to fully account for interlinked spatio-temporal changes. In this study, we demonstrate and promote the use of tensor decomposition for disentangling spatio-temporal community dynamics in long-term monitoring data. Tensor decomposition builds on traditional multivariate statistics (e...
2017: PloS One
https://www.readbyqxmd.com/read/29135953/spatial-temporal-dynamics-of-cropping-frequency-in-hubei-province-over-2001-2015
#11
Jianbin Tao, Wenbin Wu, Wenbin Liu
Mapping crop patterns with remote sensing data is of great importance for agricultural production, food security and agricultural sustainability. In this paper, a hierarchical clustering method was proposed to map cropping frequency from time-series Moderate Resolution Imaging Spectroradiometer (MODIS) Enhanced Vegetation Indices (EVI) data and the spatial and temporal patterns of cropping frequency from 2001 to 2015 in Hubei Province of China were analyzed. The results are as follows: (1) The total double crop areas decreased slightly, while total single crop areas decreased significantly during 2001 and 2015; (2) The transfer between double crop and single crop was frequent in Hubei with about 11~15% croplands changed their cropping frequency every 5 years; (3) The crop system has obvious regional differentiation for their change trend at the county level...
November 14, 2017: Sensors
https://www.readbyqxmd.com/read/29134102/imperial-trophy-or-island-relict-a-new-extinction-paradigm-for-p%C3%A3-re-david-s-deer-a-chinese-conservation-icon
#12
Samuel T Turvey, Ian Barnes, Melissa Marr, Selina Brace
Determining the 'dynamic biogeography' of range collapse in threatened species is essential for effective conservation, but reconstruction of spatio-temporal patterns of population vulnerability and resilience can require use of non-standard ecological data such as historical archives. Père David's deer or milu, one of the few living mammal species that has become extinct in the wild, is historically known only from a small captive herd of unknown provenance that survived until 1900 in the Imperial Hunting Park near Beijing, from which all living individuals are descended...
October 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29132975/a-novel-temporal-pattern-of-childhood-cerebral-x-linked-adrenoleukodystrophy
#13
Emanuela C Turco, Francesca Ormitti, Anna Andreolli, Marina Barsacchi, Carlotta Facini, Francesco Pisani
We report a 9-year-old boy, with childhood cerebral X-linked adrenoleukodystrophy (CCALD), presenting with an episode of loss of consciousness, fixed gaze, hypotonia and vomit with spontaneous resolution and post-ictal sleep. Behavioural impairment has been observed since the previous five months. Magnetic Resonance Images (MRI) revealed isolated bilateral, symmetric, confluent temporal white matter lesions involving also corticospinal tracts, with sparing of the parieto-occipital and frontal white matter. This report outlines an atypical neuroradiological localization of X-linked adrenoleukodystrophy and neuropsychological findings not specifically related to the brain involvement seen at the MRI...
November 10, 2017: Brain & Development
https://www.readbyqxmd.com/read/29125866/inconsistent-selection-of-outcomes-and-measurement-devices-found-in-shoulder-arthroplasty-research-an-analysis-of-studies-on-clinicaltrials-gov
#14
Matthew Thomas Sims, Byron Nice Detweiler, Jared Thomas Scott, Benjamin McKinnley Howard, Grant Richard Detten, Matt Vassar
INTRODUCTION: Recent evidence suggests a lack of standardization of shoulder arthroplasty outcomes. This issue is a limiting factor in systematic reviews. Core outcome set (COS) methodology could address this problem by delineating a minimum set of outcomes for measurement in all shoulder arthroplasty trials. METHODS: A ClinicalTrials.gov search yielded 114 results. Eligible trials were coded on the following characteristics: study status, study type, arthroplasty type, sample size, measured outcomes, outcome measurement device, specific metric of measurement, method of aggregation, outcome classification, and adverse events...
2017: PloS One
https://www.readbyqxmd.com/read/29124457/when-does-premature-treatment-termination-occur-examining-session-by-session-dropout-among-clients-with-gambling-disorder
#15
Rory A Pfund, Samuel C Peter, James P Whelan, Andrew W Meyers
Premature termination challenges the successful outcomes of psychological treatments for gambling disorder. To date, research has primarily identified clients who are at particular risk for dropping out of treatment. A smaller but growing body of literature has investigated when dropout occurs. Typically, those studies have not considered improvement in psychological distress within their operationalizations of dropout and therefore may have misrepresented when dropout occurs. The current study examined when dropout occurs using an operationalization based on the criteria of attaining reliable change in a naturalistic sample of clients with gambling disorder, and the classification rates yielded from that operationalization were compared to the rates from a more common operationalization...
November 9, 2017: Journal of Gambling Studies
https://www.readbyqxmd.com/read/29122343/seasonal-variations-of-nitrous-oxide-fluxes-and-soil-denitrification-rates-in-subtropical-freshwater-and-brackish-tidal-marshes-of-the-min-river-estuary
#16
Xuming Wang, Minjie Hu, Hongchang Ren, Jiabing Li, Chuan Tong, Ronald S Musenze
Estuarine tidal marshes provide favorable conditions for nitrous oxide (N2O) production. Saltwater intrusion caused by sea-level rise would exert complex effects on the production and emission of N2O in estuarine tidal marshes; however, few studies have been conducted on its effects on N2O emissions. Salinity gradients are a common occurrence in estuarine tidal marshes. Studies on production and emission of N2O in tidal marshes with different salinities may elucidate the impact of saltwater intrusion on the emission of greenhouse gases...
November 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29120827/detection-and-estimation-of-the-increasing-trend-of-cancer-incidence-in-relatively-small-populations
#17
Rina Chen, Enrique Y Bitchatchi
BACKGROUND: Detection and estimation of trends in cancer incidence rates are commonly achieved by fitting standardized rates to a joinpoint log-linear regression. The efficiency of this approach is inadequate when applied to a relatively low levels of incidence. We compared that approach with the Cuscore test with respect to detecting a log-linear increasing trend of chronic myelomonocytic leukemia (CMML) in datasets simulated to match a province of about 700,000 inhabitants. METHODS: For better efficiency, we replaced the standardized rate as the dependent variable with a continuous statistic that reflects the inverse of the standardized incidence ratio (SIR)...
October 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/29118381/a-mathematical-model-of-the-impact-of-insulin-secretion-dynamics-on-selective-hepatic-insulin-resistance
#18
Gang Zhao, Dagmar Wirth, Ingo Schmitz, Michael Meyer-Hermann
Physiological insulin secretion exhibits various temporal patterns, the dysregulation of which is involved in diabetes development. We analyzed the impact of first-phase and pulsatile insulin release on glucose and lipid control with various hepatic insulin signaling networks. The mathematical model suggests that atypical protein kinase C (aPKC) undergoes a bistable switch-on and switch-off, under the control of insulin receptor substrate 2 (IRS2). The activation of IRS1 and IRS2 is temporally separated due to the inhibition of IRS1 by aPKC...
November 8, 2017: Nature Communications
https://www.readbyqxmd.com/read/29117203/using-functional-data-analysis-to-understand-daily-activity-levels-and-patterns-in-primary-school-aged-children-cross-sectional-analysis-of-a-uk-wide-study
#19
Francesco Sera, Lucy J Griffiths, Carol Dezateux, Marco Geraci, Mario Cortina-Borja
BACKGROUND: Temporal characterisation of physical activity in children is required for effective strategies to increase physical activity (PA). Evidence regarding determinants of physical activity in childhood and their time-dependent patterns remain inconclusive. We used functional data analysis (FDA) to model temporal profiles of daily activity, measured objectively using accelerometers, to identify diurnal and seasonal PA patterns in a nationally representative sample of primary school-aged UK children...
2017: PloS One
https://www.readbyqxmd.com/read/29114869/ethno-nationalist-populism-and-the-mobilization-of-collective-resentment
#20
Bart Bonikowski
Scholarly and journalistic accounts of the recent successes of radical-right politics in Europe and the United States, including the Brexit referendum and the Trump campaign, tend to conflate three phenomena: populism, ethno-nationalism and authoritarianism. While all three are important elements of the radical right, they are neither coterminous nor limited to the right. The resulting lack of analytical clarity has hindered accounts of the causes and consequences of ethno-nationalist populism. To address this problem, I bring together existing research on nationalism, populism and authoritarianism in contemporary democracies to precisely define these concepts and examine temporal patterns in their supply and demand, that is, politicians' discursive strategies and the corresponding public attitudes...
November 2017: British Journal of Sociology
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