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https://www.readbyqxmd.com/read/28549361/-leukocyte-esterase-as-a-diagnostic-tool-for-an-infectious-disease-of-the-knee
#1
S U Ceja-Picazo, S Fuentes-Figueroa, A H Rivera-Villa, A R Hernández-Salgado, R Torres-González, A M Pérez, J A Hernández-García, J M Pérez-Atanasio
BACKGROUND: Articular infection is an orthopedic challenge due to its difficult diagnosis and devastating results. Various diagnostic studies exist: culture, ESR, CRP, count of leukocytes, among others, but none is specific, they all take more than 30 minutes to complete, and require complex infrastructure. In this study, we determine the sensitivity and specificity of the leukocyte esterase for detection of an infectious process joint in Mexican population. MATERIAL AND METHODS: During November 2015 to April 2016, we obtained synovial fluid from two groups of patients: one with a diagnosis of synovial joint infection with or without implant, and the control group, without infection but with degenerative pathology of the knee...
November 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28549239/comparing-recall-vs-recognition-measures-of-accident-under-reporting-a-two-country-examination
#2
Tahira M Probst, Laura Petitta, Claudio Barbaranelli
A growing body of research suggests that national injury surveillance data significantly underestimate the true number of non-fatal occupational injuries due to employee under-reporting of workplace accidents. Given the importance of accurately measuring such under-reporting, the purpose of the current research was to examine the psychometric properties of two different techniques used to operationalize accident under-reporting, one using a free recall methodology and the other a recognition-based approach...
May 23, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28548610/harnessing-youth-and-young-adult-culture-improving-the-reach-and-engagement-of-the-truth%C3%A2-campaign
#3
Elizabeth Hair, Lindsay Pitzer, Morgane Bennett, Michael Halenar, Jessica Rath, Jennifer Cantrell, Nicole Dorrler, Eric Asche, Donna Vallone
The national youth and young adult tobacco prevention mass media campaign, truth®, relaunched in 2014 with the goal of creating "the generation that ends smoking." The objective of this study was to assess whether the strategy of airing truth ads during popular, culturally relevant televised events was associated with higher ad and brand awareness and increases in social media engagement. Awareness of six truth advertisements that aired during popular television events and self-reported social media engagement were assessed via cross-sectional online surveys of youth and young adults aged 15-21 years...
May 26, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/28547529/toll-like-receptor-4-tlr4-and-triggering-receptor-expressed-on-myeloid-cells-2-trem-2-activation-balance-astrocyte-polarization-into-a-proinflammatory-phenotype
#4
Gerardo Rosciszewski, Vanesa Cadena, Veronica Murta, Jeronimo Lukin, Alejandro Villarreal, Thierry Roger, Alberto Javier Ramos
Astrocytes react to brain injury with a generic response known as reactive gliosis, which involves activation of multiple intracellular pathways including several that may be beneficial for neuronal survival. However, by unknown mechanisms, reactive astrocytes can polarize into a proinflammatory phenotype that induces neurodegeneration. In order to study reactive gliosis and astroglial polarization into a proinflammatory phenotype, we used cortical devascularization-induced brain ischemia in Wistar rats and primary astroglial cell cultures exposed to oxygen-glucose deprivation (OGD)...
May 25, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28546984/the-comparison-of-printed-resources-bacterial-contamination-in-libraries-of-al-zahra-hospital-and-sciences-faculty-of-isfahan-university-and-the-determination-of-their-antibiotic-sensitivity-pattern
#5
Hosein Rafiei, Mostafa Chadeganipour, Rezvan Ojaghi, Mohammad Reza Maracy, Rasool Nouri
INTRODUCTION: During the library loan process, the printed resources can be a carrier of pathogenic bacteria. In this study, it was tried to compare the Bacterial Contamination Rates and their antibiotic sensitivity pattern in printed resources of a hospital and a non-hospital library. METHODS: This is a cross-sectional study. Returning books from the Al-Zahra hospital library and library of Sciences faculty of Isfahan University provides the research community...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28546688/collagen-cross-linking-for-microbial-keratitis
#6
Prashant Garg, Sujata Das, Aravind Roy
Collagen cross-linking is gaining popularity not only for arresting the progression of keratoconus but also other indications including management of corneal infections. In this review article, we analyzed the published literature to understand the level of evidence for its use in corneal ulcer. Photoactivated riboflavin and ultraviolet A light are known to possess antimicrobial properties. The treatment also induces formation of inter- and intra-fibrillar bonds, thereby making the corneal collagen resistant to the action of proteases arresting stromal melt...
January 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28546273/mir-146a-5p-plays-an-essential-role-in-the-aberrant-epithelial-fibroblast-cross-talk-in-copd
#7
Emmanuel T Osei, Laura Florez-Sampedro, Hataitip Tasena, Alen Faiz, Jacobien A Noordhoek, Wim Timens, Dirkje S Postma, Tillie L Hackett, Irene H Heijink, Corry-Anke Brandsma
We previously reported that epithelial-derived interleukin (IL)-1α drives fibroblast-derived inflammation in the lung epithelial-mesenchymal trophic unit. Since miR-146a-5p has been shown to negatively regulate IL-1 signalling, we investigated the role of miR-146a-5p in the regulation of IL-1α-driven inflammation in chronic obstructive pulmonary disease (COPD).Human bronchial epithelial (16HBE14o-) cells were co-cultured with control and COPD-derived primary human lung fibroblasts (PHLFs), and miR-146a-5p expression was assessed with and without IL-1α neutralising antibody...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28544959/effect-of-different-mineralization-processes-on-in-vitro-and-in-vivo-bone-regeneration-and-osteoblast-macrophage-cross-talk-in-co-culture-system-using-dual-growth-factor-mediated-non-mulberry-silk-fibroin-grafted-poly-%C3%B0-caprolactone-nanofibrous-scaffold
#8
Promita Bhattacharjee, Tapas K Maiti, Debasis Bhattacharya, Samit Kumar Nandi
This study evaluates mineralized nanofibrous polymeric scaffolds at supporting in vitro osteogenic differentiation of human mesenchymal stem cells (hMSCs) and in vivo bone tissue regeneration. Co-electrospin, alternative soaking, and electrodeposition were used to introduce hydroxyapatite in non-mulberry silk fibroin grafted poly(Є-caprolactone) nanofibrous scaffolds. Bone morphogenic protein-2 and Transforming growth factor-β, at a potency ratio of 1:1, are covalently coupled onto the scaffolds. hMSCs proliferation and interactions are studied through MTT and Alamar blue assay and scanning electron and confocal microscopy...
May 16, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28544339/family-functioning-and-perceived-support-from-nurses-during-cancer-treatment-among-danish-and-australian-patients-and-their-families
#9
Karin B Dieperink, Elisabeth Coyne, Debra K Creedy, Birte Østergaard
AIMS AND OBJECTIVES: This study aims to compare family functioning and perceptions of support from nurses among Danish and Australian adult oncology patients and family members. BACKGROUND: Family can have a strong influence on the health of individuals, providing support during a health crisis such as cancer. However, family functioning and supportive care from nurses may vary across cultures and settings. DESIGN AND METHODS: A descriptive, cross sectional comparative design with patients and family members from Denmark and Australia...
May 25, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28543408/validation-and-cross-cultural-adaptation-of-the-arabic-version-of-the-nasal-obstruction-symptom-evaluation-scale
#10
Mohamed A Amer, Ibrahim A Kabbash, Ahmed A Yonis, Saad Elzayat, Mohamed O Tomoum
OBJECTIVES/HYPOTHESIS: Validation and cross-cultural adaptation of the Nasal Obstruction Symptom Evaluation (NOSE) scale into the Arabic language with studying of its psychometric properties. STUDY DESIGN: Prospective instrument-validation study. METHODS: Guidelines for the cross-cultural adaptation process from the original English language scale into the Arabic language version were followed. We assessed the psychometric properties of the Arabic version of the NOSE scale (A-NOSE) (feasibility, reproducibility, internal consistency, reliability, discriminatory validity, responsiveness to change) in 101 consecutive patients who underwent septal surgery (preoperatively and 3 months postoperatively) and 102 asymptomatic controls...
May 23, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28543089/treatments-for-people-living-with-schizophrenia-in-sub-saharan-africa-an-adapted-realist-review
#11
REVIEW
S Chidarikire, M Cross, I Skinner, M Cleary
AIM: To identify the treatments and interventions available and their impact on people living with schizophrenia in Sub-Saharan Africa. BACKGROUND: Help-seeking behaviour and the choice of treatment are largely influenced by socio-cultural factors and beliefs about the causes of mental illness. This review addresses the gap in knowledge regarding the treatment options available to people living with schizophrenia in Sub-Saharan Africa. DESIGN: Adapted realist literature review...
May 25, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28543060/nogo-b-is-the-major-form-of-nogo-at-the-floor-plate-and-likely-mediates-crossing-of-commissural-axons-in-the-mouse-spinal-cord
#12
Liqing Wang, Chao Yu, Jun Wang, Peggy Leung, Ding Ma, Hui Zhao, Jeremy S H Taylor, Sun-On Chan
Using Nogo antibodies with defined binding specificity, Nogo-B, but not Nogo-A, was localized on radial glia in the floor plate of mouse embryos. The presence of Nogo-B was confirmed in Nogo-A knockout mice. In explant cultures of embryonic day (E) 11 and E12 spinal cord, blocking of NgR function with antagonist peptide NEP1-40 reduced the crossing of newly arrived commissural axons, resulting in an accumulation of growth cones in the floor plate. Analysis of growth cone morphology demonstrated an increase in size of growth cones in the floor plate after peptide treatment, which was not detected in axons growing towards the midline...
May 22, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28542573/development-of-real-time-pcr-and-loop-mediated-isothermal-amplification-lamp-assays-for-the-differential-detection-of-digital-dermatitis-associated-treponemes
#13
Kelly Anklam, Megan Kulow, Wataru Yamazaki, Dörte Döpfer
Bovine digital dermatitis (DD) is a severe infectious cause of lameness in cattle worldwide, with important economic and welfare consequences. There are three treponeme phylogroups (T. pedis, T. phagedenis, and T. medium) that are implicated in playing an important causative role in DD. This study was conducted to develop real-time PCR and loop-mediated isothermal amplification (LAMP) assays for the detection and differentiation of the three treponeme phylogroups associated with DD. The real-time PCR treponeme phylogroup assays targeted the 16S-23S rDNA intergenic space (ITS) for T...
2017: PloS One
https://www.readbyqxmd.com/read/28542539/a-leishmania-secretion-system-for-the-expression-of-major-ampullate-spidroin-mimics
#14
Todd A Lyda, Elizabeth L Wagner, Andre X Bourg, Congyue Peng, Golnaz Najaf Tomaraei, Delphine Dean, Marian S Kennedy, William R Marcotte
Spider major ampullate silk fibers have been shown to display a unique combination of relatively high fracture strength and toughness compared to other fibers and show potential for tissue engineering scaffolds. While it is not possible to mass produce native spider silks, the potential ability to produce fibers from recombinant spider silk fibers could allow for an increased innovation rate within tissue engineering and regenerative medicine. In this pilot study, we improved upon a prior fabrication route by both changing the expression host and additives to the fiber pulling precursor solution to improve the performance of fibers...
2017: PloS One
https://www.readbyqxmd.com/read/28542525/women-s-role-in-sanitation-decision-making-in-rural-coastal-odisha-india
#15
Parimita Routray, Belen Torondel, Thomas Clasen, Wolf-Peter Schmidt
BACKGROUND: While women and girls face special risks from lack of access to sanitation facilities, their ability to participate and influence household-level sanitation is not well understood. This paper examines the association between women's decision-making autonomy and latrine construction in rural areas of Odisha, India. METHODS: We conducted a mixed-method study among rural households in Puri district. This included a cross sectional survey among 475 randomly selected households...
2017: PloS One
https://www.readbyqxmd.com/read/28542225/the-impact-of-health-promotion-on-trachoma-knowledge-attitudes-and-practice-kap-of-staff-in-three-work-settings-in-remote-indigenous-communities-in-the-northern-territory
#16
Fiona D Lange, Kelly Jones, Rebecca Ritte, Haley E Brown, Hugh R Taylor
BACKGROUND: Globally, trachoma is the leading cause of infectious blindness and Australia is the only developed country with endemic trachoma. It is found in remote Indigenous communities burdened with poverty, overcrowding and poor hygiene. Lack of culturally appropriate health promotion, a small trachoma workforce and lack of awareness and support for trachoma elimination in general, were early barriers. METHODS: A cross-sectional pre-post study using a convenience sample, was conducted in clinics, schools and community work-settings from 63 of the 82 remote Aboriginal communities identified as being at risk of trachoma in the Northern Territory (NT)...
May 24, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28541817/gendered-cultural-identities-the-influences-of-family-and-privacy-boundaries-subjective-norms-and-stigma-beliefs-on-family-health-history-communication
#17
Soo Jung Hong
This study investigates the effects of cultural norms on family health history (FHH) communication in the American, Chinese, and Korean cultures. More particularly, this study focuses on perceived family boundaries, subjective norms, stigma beliefs, and privacy boundaries, including age and gender, that affect people's FHH communication. For data analyses, hierarchical multiple regression and logistic regression methods were employed. The results indicate that participants' subjective norms, stigma beliefs, and perceived family/privacy boundaries were positively associated with current FHH communication...
May 25, 2017: Health Communication
https://www.readbyqxmd.com/read/28539658/functional-compressive-mechanics-and-tissue-biocompatibility-of-an-injectable-sf-pu-hydrogel-for-nucleus-pulposus-replacement
#18
Jingen Hu, Yang Lu, Ling Cai, Kwabena Gyabaah Owusu-Ansah, Gewen Xu, Feilong Han, Junjie Bao, Xiangjin Lin, Yiping Huang
In spinal degenerative disease, an injectable liquid hydrogel can fill in defect entirely, lessen the danger of implant relocation and following loss of disc height, minimizing the operative trauma. Here, we propose an injectable in-situ chemically cross-linked hydrogel by a two-component reaction of liquid silk fibroin with liquid polyurethane at physiological temperature conditions. Confined compression tests and fatigue tests were reported to assess physical properties of the hydrogel. Impact of different diameter on the biomechanical behaviours was tested to evaluate the clinical potentiality of the hydrogel for replacing nucleus pulposus...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28539084/creating-safer-health-systems-lessons-from-other-sectors-and-an-account-of-an-application-in-the-safer-clinical-systems-programme
#19
Peter Spurgeon, Hugh Flanagan, Matthew Cooke, Mark Sujan, Stephen Cross, Rose Jarvis
Despite well meaning initiatives over decades, the percentage of inpatients suffering adverse events remains constant in most advanced health systems. The notion of incident reporting as used in other safety critical industries has proved far less effective in healthcare. This article describes a new patient safety paradigm in the search for improved patient safety in healthcare. Underpinned by a holistic use of human factors the Safer Clinical Systems programme involves a proactive, risk-based approach seeking to eliminate or control risk before it is converted to patient harm...
May 2017: Health Services Management Research
https://www.readbyqxmd.com/read/28538931/cross-cultural-adaptation-of-the-oral-anticoagulation-knowledge-test-to-the-brazilian-portuguese
#20
Marcus Fernando da Silva Praxedes, Mauro Henrique Nogueira Guimarães Abreu, Daniel Dias Ribeiro, Milena Soriano Marcolino, Saul Martins de Paiva, Maria Auxiliadora Parreiras Martins
Patients' knowledge about oral anticoagulant therapy may favor the achievement of therapeutic results and the prevention of adverse pharmacotherapy-related events. Brazil lacks validated instruments for assessing the patient's knowledge about treatment with warfarin. This study aimed to perform the cross-cultural adaptation of the Oral Anticoagulation Knowledge (OAK) Test instrument from English into Portuguese. This is a methodological study developed in an anticoagulation clinic of a public university hospital...
May 2017: Ciência & Saúde Coletiva
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