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https://www.readbyqxmd.com/read/29133223/phenotypical-differences-of-childhood-and-adult-onset-atopic-dermatitis
#1
Jonathan I Silverberg, Paras P Vakharia, Rishi Chopra, Ryan Sacotte, Neha Patel, Supriya Immaneni, Takeisha White, Robert Kantor, Derek Y Hsu
BACKGROUND: Little is known about adult-onset atopic dermatitis (AD). OBJECTIVE: To determine the associations and clinical characteristics of adult-onset AD. METHODS: A prospective study of 356 adults with AD (age ≥18 years) was performed using standardized questionnaires and examination. AD severity was assessed using the Patient-Oriented Eczema Measure, Eczema Area and Severity Index, Scoring Atopic Dermatitis, body surface area, and numeric rating scale for itch and sleeplessness...
November 10, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29117754/generation-and-characterization-of-new-alleles-of-quiver-qvr-that-encodes-an-extracellular-modulator-of-the-shaker-potassium-channel
#2
Hongyu Ruan, Atsushi Ueda, Xiaomin Xing, Xuxuan Wan, Benjamin Strub, Spencer Mukai, Kaan Certel, David Green, Kyle Belozerov, Wei-Dong Yao, Wayne Johnson, Jim Jung-Ching Lin, Arthur J Hilliker, Chun-Fang Wu
Our earlier genetic screen uncovered a paraquat-sensitive leg-shaking mutant quiver(1) (qvr(1)), whose gene product interacts with the Shaker (Sh) K(+) channel. We also mapped the qvr locus to EY04063 and noticed altered day-night activity patterns in these mutants. Such circadian behavioral defects were independently reported by another group, who employed the qvr(1) allele we supplied them, and attributed the extreme restless phenotype of EY04063 to the qvr gene. However, their report adopted a new noncanonical gene name sleepless (sss) for qvr...
November 9, 2017: Journal of Neurogenetics
https://www.readbyqxmd.com/read/29061111/normative-prosthodontic-care-need-does-it-impact-the-daily-life-of-young-saudis-with-high-level-of-oral-diseases-a-cross-sectional-study
#3
Fahad Al-Harbi, Maha El Tantawi
BACKGROUND: Assessing the need for prosthodontic care previously included older age groups. There is less information about younger populations who may need this care because of high disease levels. The aim of this study was to assess the normative need for prosthodontic care in a young Saudi population with high oral disease levels, the associated factors and its impact on daily life. METHODS: A cross sectional study included Saudi adults in the Eastern Province in 2016...
October 23, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29059210/measures-of-cardiovascular-autonomic-activity-in-insomnia-disorder-a-systematic-review
#4
REVIEW
Marina-Marinela Nano, Pedro Fonseca, Rik Vullings, Ronald M Aarts
BACKGROUND: Insomnia disorder is a widespread sleep disorder with a prevalence of approximately 10%. Even though the link between insomnia and cardiovascular activity is not exactly clear, it is generally assumed that cardiovascular autonomic modifications could occur as a result of sleeplessness, or, alternatively, that autonomic alterations could be an expression of a hyper-arousal state. This review investigates whether cardiovascular measures are different between insomniacs and controls...
2017: PloS One
https://www.readbyqxmd.com/read/29043298/professional-burnout-and-concurrent-health-complaints-in-neonatal-nursing
#5
Natalija Skorobogatova, Nida Žemaitienė, Kastytis Šmigelskas, Rasa Tamelienė
The aim of this study was to analyze nurses' professional burnout and health complaints and the relationship between the two components. METHODS: The anonymous survey included 94 neonatal intensive care nurses from two centers of perinatology. The Maslach Burnout Inventory-Human Services Survey (MBI-HSS) was used to evaluate professional burnout; it consisted of 3 components, Emotional Exhaustion, Depersonalization, and Personal Accomplishments, with 22 items in total. Health complaints were evaluated by 21 items, where nurses were asked to report the occurrence of symptoms within the last year...
2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29040744/tobacco-exposure-and-sleep-disturbance-in-498-208-uk-biobank-participants
#6
D Boakye, C A Wyse, C A Morales-Celis, S M Biello, M E S Bailey, S Dare, J Ward, J M R Gill, J P Pell, D F Mackay
Background: The prevalence of sleep disturbance is high and increasing. The study investigated whether active, former and passive smoking were associated with sleep disturbance. Methods: This cross-sectional study used data from the UK Biobank: a cohort study of 502 655 participants, of whom 498 208 provided self-reported data on smoking and sleep characteristics. Multivariable multinomial and logistic regression models were used to examine the associations between smoking and sleep disturbance...
August 30, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29031741/further-evidences-for-sleep-instability-and-impaired-spindle-delta-dynamics-in-schizophrenia-a-whole-night-polysomnography-study-with-neuroloop-gain-and-sleep-cycle-analysis
#7
Arun Sasidharan, Sunil Kumar, Ajay Kumar Nair, Ammu Lukose, Vrinda Marigowda, John P John, Bindu M Kutty
OBJECTIVE: Sleep offers a unique window into the brain dysfunctions in schizophrenia. Many past sleep studies have reported abnormalities in both macro-sleep architecture (like increased awakenings) as well as micro-sleep-architecture (like spindle deficits) in patients with schizophrenia (PSZ). The present study attempts to replicate previous reports of macro- and micro-sleep-architectural abnormalities in schizophrenia. In addition, the study also examined sleep-stage changes and spindle-delta dynamics across sleep-cycles to provide further evidence in support of the dysfunctional thalamocortical mechanisms causing sleep instability and poor sleep maintenance associated with schizophrenia pathophysiology...
October 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29029214/sleepless-night-and-day-the-plight-of-progressive-supranuclear-palsy
#8
Christine M Walsh, Leslie Ruoff, Kathleen Walker, Alaisa Emery, Jonathan Varbel, Elissaios Karageorgiou, Phi N Luong, Irida Mance, Hilary W Heuer, Adam L Boxer, Lea T Grinberg, Joel H Kramer, Bruce L Miller, Thomas C Neylan
Objectives: To elucidate the unique sleep and waking characteristics in progressive supranuclear palsy (PSP), a neurodegenerative disease associated with motor deficits and dementia that largely affects the brainstem and thalamic regions. Methods: 20 PSP and 16 healthy older adult controls participated in this study. Participants underwent an overnight polysomnography and multiple sleep latency test (MSLT) the following day. Prior to the MSLT last trial, participants were asked to complete the Stanford Sleepiness Scale...
October 5, 2017: Sleep
https://www.readbyqxmd.com/read/28966337/influences-of-low-frequency-and-other-noises-produced-by-wind-turbines-an-epidemiological-literature-review
#9
Tatsuhiko Kubo, Hideki Hasunuma, Yoshitaka Morimatsu, Yoshihisa Fujino, Kunio Hara, Tatsuya Ishitake
Objectives Due to its' environment-friendly and clean energy characteristics, wind power has been increasingly used globally, particularly in advanced countries. However, concerns about health hazards, especially due to low-frequency and other noises generated from wind turbines, have been reported repeatedly. In order to manage adverse health effects appropriately, regulatory standards or guidelines that consider the health of residents need to be developed. To provide a scientific basis for the development of such regulatory standards and guidelines, this paper conducted a literature review to analyze epidemiological studies involving residents living in the vicinity of wind farms...
2017: [Nihon Kōshū Eisei Zasshi] Japanese Journal of Public Health
https://www.readbyqxmd.com/read/28960164/cognitive-expectancies-for-hypnotic-use-among-older-adult-veterans-with-chronic-insomnia
#10
Constance H Fung, Jennifer L Martin, Karen Josephson, Lavinia Fiorentino, Joseph M Dzierzewski, Stella Jouldjian, Yeonsu Song, Juan Carlos Rodriguez Tapia, Michael N Mitchell, Cathy A Alessi
OBJECTIVES: To examine relationships between cognitive expectancies about sleep and hypnotics and use of medications commonly used for insomnia (hypnotics). METHODS: We analyzed baseline data from older veterans who met diagnostic criteria for insomnia and were enrolled in a trial comparing CBTI delivered by a supervised, sleep educator to an attention control condition (N = 159; 97% male, mean age 72 years). We classified individuals as hypnotic users (N = 23) vs...
July 20, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/28959202/a-58-year-old-male-with-cognitive-deteriorations-caused-by-septum-pellucidum-cyst-a-case-report
#11
Li-Ming Chen, Ming-Xin Zhu, Yu-Fen Zhang, Se-Hui Ma, Yao Yi, Lie-Xin Xia, Yan Wu, Lei Pei
Dementia is known to be induced by vascular dementia and certain neurodegenerative diseases. The presenting features of disordered memory, intellect and personality often result in referral to a neurologist initially. Septum pellucidum cyst (SPC) is a rare clinical finding and defined as a cystic structure between the lateral ventricles. SPC induced memory disorder and dementia has been seldom reported in which the clinical features are atypical and can be misdiagnosed. The main difficulty is to establish a correlation between symptoms and the cyst...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28893459/placing-the-patient-at-the-centre-of-chronic-wound-care-a-qualitative-evidence-synthesis
#12
REVIEW
Naomi Fearns, Stephen Heller-Murphy, Joanna Kelly, Jenny Harbour
BACKGROUND: Chronic wounds are a major health burden and have a severe impact on well-being. This synthesis of qualitative studies was undertaken to inform a health technology assessment of antimicrobial wound dressings. It aimed to explore patients' experiences of chronic wounds and determine improvements for clinical practice. METHOD: Inclusion criteria included use of qualitative methods, and English language publication. Databases searched included MEDLINE (Ovid), MEDLINE in Process (Ovid), EMBASE (Ovid), CINAHL (EBSCOHost), and PsychInfo (EBSCOHost)...
September 5, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28748168/potentiating-effects-of-perovskia-abrotanoides-karel-on-pentobarbital-induced-sleep
#13
Fatemeh Forouzanfar, Azar Hosseini, Mohammad Sadegh Amiri, Hassan Rakhshandeh
OBJECTIVE: Sleeplessness is the most common sleep disorder. In this study the hypnotic effect of the hydro-alcoholic extract (HAE) of Perovskia abrotanoides Karel. and its water fraction (WF), ethyl acetate fraction (EAF) and n-butanol fraction (NBF) were studied in mice. MATERIALS AND METHODS: The test compounds were administered intraperitoneally to mice 30 min before the administration of sodium pentobarbital (30 mg/kg.). Moreover, the influence of flumazenil on the hypnotic effect of the extracts was evaluated...
May 2017: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28635358/disability-and-the-impact-of-need-for-periodontal-care-on-quality-of-life-a-cross-sectional-study
#14
Maha El Tantawi, Adel AlAgl
Objective The need for periodontal care may negatively impact daily life. We compared the need for periodontal care and its impact on daily life between disabled and healthy adults in the Eastern Province, Saudi Arabia. Methods In this cross-sectional study of 819 adults, a questionnaire was used to assess personal background factors; the impact of periodontitis on pain, avoiding foods, embarrassment, sleeplessness, work absence, and discontinuing daily activities; and risk factors (smoking, diabetes, toothbrushing, insurance, professional tooth cleaning, and dental visits)...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28616739/petrol-filling-workers-as-biomonitor-of-pah-exposure-and-functional-health-capacity-in-resource-limited-settings-of-city-rawalpindi-pakistan
#15
Audil Rashid, Shu Tao, Ikhtiar Uddin, Atif Kamal
This is the first study from Pakistan to report the exposure of petrol filling workers (n = 120) to naphthalene (Nap) and pyrene (Pyr) in relation to their functional capacities and health outcome. A group of non-exposed subjects (controls n = 46) was also recruited for comparison. The perceived health risk of the exposed workers was monitored using a questionnaire based on the self-reporting survey. The observed physical anomalies related to the health disorder included the acidity after meals, eye redness, appetite loss, skin lesions, and dryness of oral cavity, while those related to neurasthenic symptoms included the body aches, energy loss, twitching, fatigue, sleeplessness, fainting, and irritability...
July 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28570377/part-i-the-effects-of-music-for-the-symptom-management-of-anxiety-pain-and-insomnia-in-critically-ill-patients-an-integrative-review-of-current-literature
#16
Naheed Meghani, Mary Fran Tracy, Niloufar Niakosari Hadidi, Ruth Lindquist
Critical care environments are known for provoking anxiety, pain, and sleeplessness. Often, these symptoms are attributed to patients' underlying physiological conditions; life-sustaining or life-prolonging treatments such as ventilators, invasive procedures, tubes, and monitoring lines; and noise and the fast-paced technological nature of the critical care environment. This, in turn, possibly increases length of stay and morbidity and challenges the recovery and healing of critically ill patients. Complementary therapies can be used as adjunctive therapies alongside pharmacological interventions and modalities...
July 2017: Dimensions of Critical Care Nursing: DCCN
https://www.readbyqxmd.com/read/28546818/investigating-the-relationship-between-sexual-function-and-quality-of-life-in-menopausal-women
#17
Masumeh Ghazanfarpour, Talat Khadivzadeh, Masaudeh Babakhanian
Objective: To evaluate the symptoms of menopausal women and the link between sexual function, menopausal symptoms and demographic variables. Materials and methods: This is a cross-sectional study in which 202 postmenopausal women admitted to the health care centers were selected. The Female Sexual Function Index (FSFI) questionnaire and Menopause-Specific Quality of Life (MENQOL) were the main means of data gathering. Results: The results of our study suggested that suggested that women experienced a number of menopausal symptoms such hot flash, headache and neck pains, reduced physical strength weight gain, pain or leg cramps, intensified sexual problem than women who lack such symptoms...
December 2016: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/28485036/severity-strata-for-eczema-area-and-severity-index-easi-modified-easi-scoring-atopic-dermatitis-scorad-objective-scorad-atopic-dermatitis-severity-index-and-body-surface-area-in-adolescents-and-adults-with-atopic-dermatitis
#18
R Chopra, P P Vakharia, R Sacotte, N Patel, S Immaneni, T White, R Kantor, D Y Hsu, J I Silverberg
BACKGROUND: Scoring systems for assessing the signs of atopic dermatitis (AD) are complex and difficult to interpret. Severity strata are helpful to interpret these assessments properly. OBJECTIVES: To confirm previously reported strata for the Eczema Area and Severity Index (EASI), Scoring Atopic Dermatitis (SCORAD) and the objective component of SCORAD (oSCORAD), and to develop strata for the modified EASI (mEASI), Atopic Dermatitis Severity Index (ADSI) and body surface area (BSA) for use in adults with AD...
May 9, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28482453/health-hazards-and-adoption-of-personal-protective-equipment-during-cotton-harvesting-in-pakistan
#19
Khuda Bakhsh, Nameem Ahmad, Shanza Tabasum, Sarfraz Hassan, Ishtiaq Hassan
The use of personal protective equipment (PPE) during cotton harvesting is critical for securing better health for female cotton pickers in the developing countries where health facilities are not sufficiently available to the masses in the rural areas. Despite increasing the efforts in increasing awareness about the benefits of PPE among the farm workers, a vast majority of the farm workers including pickers don't use the PPE. The present study examines health impacts of cotton harvesting in Pakistani Punjab along with the factors affecting the use of PPE among the cotton pickers...
November 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28458939/isotretinoin-as-a-possible-environmental-trigger-to-autoimmunity-in-genetically-susceptible-patients
#20
Jocelyn Nugroho, Bahareh Schweiger
Introduction. Isotretinoin is commonly used to treat cystic acne. Definitive mechanisms of action for isotretinoin are not known though despite many side effects having been documented. Various case reports have noted autoimmune diseases succeeding isotretinoin treatment. Case Report. A 16-year-old female presents with symptoms of tremors, lack of focus, sleeplessness, emotional liability, bulging eyes, loose stools, heat intolerance, and missed menstrual periods. Symptoms manifested shortly after the patient finished a course of oral isotretinoin treatment for acne...
2017: Case Reports in Pediatrics
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