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Eric S Zhou, Karen Clark, Christopher J Recklitis, Richard Obenchain, Matthew Loscalzo
PURPOSE: Cancer patients are likely to experience sleep problems. Understanding their perception of sleep problems is important as subjective symptom experience is associated with treatment-seeking behavior. We explored the prevalence of sleep problems and its correlates in a large sample of cancer patients at an important but understudied stage of their cancer journey: prior to initiating treatment. METHODS: Cancer patients (5702) (67.5% female; 76.9% White; 23...
March 15, 2018: International Journal of Behavioral Medicine
Murray B Stein, Michael J McCarthy, Chia-Yen Chen, Sonia Jain, Joel Gelernter, Feng He, Steven G Heeringa, Ronald C Kessler, Matthew K Nock, Stephan Ripke, Xiaoying Sun, Gary H Wynn, Jordan W Smoller, Robert J Ursano
Insomnia is a worldwide problem with substantial deleterious health effects. Twin studies have shown a heritable basis for various sleep-related traits, including insomnia, but robust genetic risk variants have just recently begun to be identified. We conducted genome-wide association studies (GWAS) of soldiers in the Army Study To Assess Risk and Resilience in Servicemembers (STARRS). GWAS were carried out separately for each ancestral group (EUR, AFR, LAT) using logistic regression for each of the STARRS component studies (including 3,237 cases and 14,414 controls), and then meta-analysis was conducted across studies and ancestral groups...
March 8, 2018: Molecular Psychiatry
Donghai Li, Jinhai Zhao, Zhouyuan Yang, Pengde Kang, Bin Shen, Fuxing Pei
Low doses of corticosteroids have been proved to be effective in decreasing the inflammatory cytokines and relieving the pain. However, the optimal dosage of corticosteroids in total knee arthroplasty (TKA) is undetermined. A total of 103 patients were randomly divided into three groups. Group A containing 32 patients received normal saline. Group B including 36 patients used two doses of 100 mg hydrocortisone, given 2 hours before and 8 hours after surgery. Group C involving 35 patients received four doses of 100 mg hydrocortisone, 8 hours apart...
March 7, 2018: Journal of Knee Surgery
Yong-Seok Jee
Recently, whole body-electromyostimulation (WB-EMS) has upgraded its functions and capabilities and has overcome limitations and inconveniences from past systems. Although the efficacy and safety of EMS have been examined in some studies, specific guidelines for applying WB-EMS are lacking. To determine the efficacy and safety of applying it in healthy men to improve cardiopulmonary and psychophysiological variables when applying WB-EMS. Sixty-four participants were randomly grouped into control group (without electrical stimuli) or WB-EMS group after a 6-week baseline period...
February 2018: Journal of Exercise Rehabilitation
Iain Brassington
The lack of sleep is a significant problem in the modern world. The structure of the economy means that 24 hour working is required from some of us, sometimes because we are expected to be able to respond to share-price fluctuations on the other side of the planet, sometimes because we are expected to serve kebabs to people leaving nightclubs, and sometimes because lives depend on it. The immediate effect is that we feel groggy; but there may be much more sinister long-term effects of persistent sleep deprivation and disruption, the evidence for which is significant, and worth taking seriously...
April 2018: Cambridge Quarterly of Healthcare Ethics: CQ: the International Journal of Healthcare Ethics Committees
Keisuke Takano, Louise Vanden Poel, Filip Raes
BACKGROUND AND OBJECTIVES: Cognitive bias to sleep-related information is thought to be a core feature of sleep disturbances. The bias may enhance pre-sleep arousal, such as excessive worry about sleeplessness, which prevents people from initiating normal sleep onset. The present study focused on (a) attention bias toward sleep-related stimuli and (b) difficulty in updating working memory for sleep-related stimuli as two possible mechanisms underlying pre-sleep cognitive arousal. METHOD: Participants (n = 61, a community sample) completed a dot-probe task (with sleep-related and matched control word stimuli) and a 1-back and 2-back task (with sleep-related and non-sleep-related pictorial stimuli)...
February 21, 2018: Journal of Behavior Therapy and Experimental Psychiatry
Elena Vorona, Eberhard Nieschlag
Despite the fact that sports organizations and legislators have introduced various mechanisms to discourage athletes from using performance and appearance enhancing substances a high percentage of athletes admits to their unabated application. In competitive athletics, bodybuilding and in recreational sports anabolic androgenic steroids (AAS) continue to be the substances most abused. This review summarizes the side effects of AAS abuse on organs and system functions in both sexes. High doses of AAS cause a significant increase of erythrocytes und haemoglobin concentration, which may lead to thromboembolism, intracardiac thrombosis and stroke...
February 19, 2018: Minerva Endocrinologica
Ahmed Mohamed Maged, Amr H Abbassy, Hend R S Sakr, Heba Elsawah, Heba Wagih, Asmaa I Ogila, Amal Kotb
OBJECTIVE: To study the effectiveness of performing swimming on the severity of symptoms of premenstrual syndrome (PMS). MATERIALS AND METHODS: A randomized controlled trial that was conducted on 70 women diagnosed with PMS divided randomly into two equal groups: Group I included women who engaged into exercise and group II controls. Daily Symptoms Report was filled at the start and at end of the study. RESULTS: At the posttreatment evaluation, there was a highly significant difference between the study and control groups regarding anxiety (0 vs...
January 19, 2018: Archives of Gynecology and Obstetrics
Risto Isomeri, Marja Mikkelsson, Markku Partinen, Markku J Kauppi
The aim of this study is to find out the outcome of 28 patients who got the diagnosis of primary fibromyalgia (pFM) 26 years ago. In 1986, 56 patients with widespread pain were examined and filled in a base questionnaire (BQ). Of them, 42 fulfilled the Yunus criteria for pFM. Twenty-six years later, addresses of 38 patients were found, and an extensive follow-up questionnaire (FupQ) was mailed to them. Of them, 28 (74%) answered the FupQ. This included nine identical questions with the BQ and questions concerning changes in their symptoms and quality of life (Qol)...
January 9, 2018: Clinical Rheumatology
Bailey Heminger, Daniel J Sheridan
No abstract text is available yet for this article.
January 2018: Nursing
İlkay Boz, Nida Selvi
BACKGROUND: Postpartum sleeplessness has been observed to be an important health problem in Turkey. However, no scale is currently available to evaluate quality of sleep in Turkish postpartum women. PURPOSE: The aim of this study was to test the validity and reliability of the Turkish Postpartum Sleep Quality Scale (T-PSQS). METHODS: The sample of this methodological study surveyed 100 women during their first 2 postpartum weeks. Data were obtained using a personal characteristics form and the PSQS...
December 6, 2017: Journal of Nursing Research: JNR
Richard Ac Hughes, Man Mohan Mehndiratta, Yusuf A Rajabally
BACKGROUND: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a progressive or relapsing and remitting paralysing illness, probably due to an autoimmune response, which should benefit from corticosteroid treatment. Non-randomised studies suggest that corticosteroids are beneficial. Two commonly used corticosteroids are prednisone and prednisolone. Both are usually given as oral tablets. Prednisone is converted into prednisolone in the liver so that the effect of the two drugs is usually the same...
November 29, 2017: Cochrane Database of Systematic Reviews
Makoto Kobayakawa, Asao Ogawa, Michiko Konno, Akiko Kurata, Jun Hamano, Tatsuya Morita, Yoshiyuki Kizawa, Satoru Tsuneto, Yasuo Shima, Maho Aoyama, Mitsunori Miyashita
OBJECTIVE: The psychological and psychiatric symptoms of terminally ill cancer patients are highly problematic and have been associated with greater burden among caregivers. Until now, the extent of these problems in the home care setting was unclear. METHODS: This retrospective study was conducted as part of a nationwide survey from the perspective of bereaved family members in Japan (J-HOPE3). The bereaved family members rated the symptoms of delirium and suicidal ideation of patients with cancer, and the sleeplessness and depressed mood of family caregivers utilizing home care services in the one month before the patients' deaths...
December 2017: Journal of Psychosomatic Research
K Chu, Y Song, N D Chatooah, Q Weng, Q Ying, L Ma, F Qu, J Zhou
OBJECTIVE: The use of hormone replacement therapy (HRT) started later in China than in European countries. The purpose of the present study was to investigate HRT patterns and reasons for the initiation and discontinuation of HRT among women in South China. METHODS: A telephone survey about menopausal status, the use of HRT, reasons for HRT discontinuation and duration of HRT treatment was conducted in 2014. RESULTS: A total of 825 telephone surveys were carried out, and 217 previous HRT users and 390 current users were recruited for this study...
November 23, 2017: Climacteric: the Journal of the International Menopause Society
Keisuke Takano, Filip Raes
Biased information processing has been highlighted as a possible vulnerability factor for sleep problems. A theory states that perceived sleeplessness triggers a strong approach motivation (or craving) for sleep, and then activates persistent preoccupation with sleep. However, there is no clear evidence that perceived sleeplessness is associated with such a motivation toward sleep-related information. Thus, we examined the untested idea that people with subjective sleep disturbances would prefer sleep-related topics, using a modified version of the pay-per-view task...
November 13, 2017: Behaviour Research and Therapy
Jonathan I Silverberg, Paras P Vakharia, Rishi Chopra, Ryan Sacotte, Neha Patel, Supriya Immaneni, Takeisha White, Robert Kantor, Derek Y Hsu
BACKGROUND: Little is known about adult-onset atopic dermatitis (AD). OBJECTIVE: To determine the associations and clinical characteristics of adult-onset AD. METHODS: A prospective study of 356 adults with AD (age ≥18 years) was performed using standardized questionnaires and examination. AD severity was assessed using the Patient-Oriented Eczema Measure, Eczema Area and Severity Index, Scoring Atopic Dermatitis, body surface area, and numeric rating scale for itch and sleeplessness...
November 10, 2017: Journal of Allergy and Clinical Immunology in Practice
Hongyu Ruan, Atsushi Ueda, Xiaomin Xing, Xuxuan Wan, Benjamin Strub, Spencer Mukai, Kaan Certel, David Green, Kyle Belozerov, Wei-Dong Yao, Wayne Johnson, Jim Jung-Ching Lin, Arthur J Hilliker, Chun-Fang Wu
Our earlier genetic screen uncovered a paraquat-sensitive leg-shaking mutant quiver(1) (qvr(1)), whose gene product interacts with the Shaker (Sh) K(+) channel. We also mapped the qvr locus to EY04063 and noticed altered day-night activity patterns in these mutants. Such circadian behavioral defects were independently reported by another group, who employed the qvr(1) allele we supplied them, and attributed the extreme restless phenotype of EY04063 to the qvr gene. However, their report adopted a new noncanonical gene name sleepless (sss) for qvr...
November 9, 2017: Journal of Neurogenetics
Fahad Al-Harbi, Maha El Tantawi
BACKGROUND: Assessing the need for prosthodontic care previously included older age groups. There is less information about younger populations who may need this care because of high disease levels. The aim of this study was to assess the normative need for prosthodontic care in a young Saudi population with high oral disease levels, the associated factors and its impact on daily life. METHODS: A cross sectional study included Saudi adults in the Eastern Province in 2016...
October 23, 2017: BMC Oral Health
Marina-Marinela Nano, Pedro Fonseca, Rik Vullings, Ronald M Aarts
BACKGROUND: Insomnia disorder is a widespread sleep disorder with a prevalence of approximately 10%. Even though the link between insomnia and cardiovascular activity is not exactly clear, it is generally assumed that cardiovascular autonomic modifications could occur as a result of sleeplessness, or, alternatively, that autonomic alterations could be an expression of a hyper-arousal state. This review investigates whether cardiovascular measures are different between insomniacs and controls...
2017: PloS One
Natalija Skorobogatova, Nida Žemaitienė, Kastytis Šmigelskas, Rasa Tamelienė
The aim of this study was to analyze nurses' professional burnout and health complaints and the relationship between the two components. METHODS: The anonymous survey included 94 neonatal intensive care nurses from two centers of perinatology. The Maslach Burnout Inventory-Human Services Survey (MBI-HSS) was used to evaluate professional burnout; it consisted of 3 components, Emotional Exhaustion, Depersonalization, and Personal Accomplishments, with 22 items in total. Health complaints were evaluated by 21 items, where nurses were asked to report the occurrence of symptoms within the last year...
2017: Open Medicine (Warsaw, Poland)
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