Nicolette A Cilenti, Jaclyn G Tamaroff, Christopher J Capiola, Walter Faig, Michael G McBride, Stephen M Paridon, Shannon O'Malley, Jonathan B Edelson, David R Lynch, Shana E McCormack, Kimberly Y Lin
INTRODUCTION/AIMS: Traditional exercise is often difficult for individuals with Friedreich ataxia (FRDA), and evidence is limited regarding how to measure exercise performance in this population. We evaluated the feasibility, reliability, and natural history of adaptive cardiopulmonary exercise test (CPET) performance in children and adults with FRDA. METHODS: Participants underwent CPET on either an arm cycle ergometer (ACE) or recumbent leg cycle ergometer (RLCE) at up to four visits (baseline, 2 weeks, 4 weeks, and 1 year)...
March 21, 2024: Muscle & Nerve