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https://www.readbyqxmd.com/read/29316159/safety-of-extraperitoneal-rectal-resection-and-ileo-or-colorectal-anastomosis-without-loop-ileostomy-in-patients-with-peritoneal-metastases-treated-with-crs-and-hipec
#1
Andreas Brandl, Wieland Raue, Felix Aigner, Maria Clara Arroyave, Johann Pratschke, Beate Rau
AIM: Extraperitoneal rectal resection combined with complete peritonectomy of the pelvis in patients with peritoneal metastases is associated with a high rate of morbidity and mortality due to anastomotic leakage (AL). Therefore, many centers tend to perform loop ileostomy to reduce the clinical impact of AL. The aim of this study was to analyze the need for protective stoma creation in this patient group to avoid major complications and mortality in the case of AL. METHOD: We analyzed 53 patients who underwent extraperitoneal rectal resection from 409 consecutive patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) at our department between January 1997 and December 2016...
January 6, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29290660/efficacy-of-noninvasive-evaluations-in-monitoring-inflammatory-bowel-disease-activity-a-prospective-study-in-china
#2
Jin-Min Chen, Tao Liu, Shan Gao, Xu-Dong Tong, Fei-Hong Deng, Biao Nie
AIM: To optimize the efficacy of noninvasive evaluations in monitoring the endoscopic activity of inflammatory bowel disease (IBD). METHODS: Fecal calprotectin (FC), clinical activity index (CDAI or CAI), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and procalcitonin (PCT) were measured for 136 IBD patients. Also, FC was measured in 25 irritable bowel syndrome (IBS) patients that served as controls. Then, endoscopic activity was determined by other two endoscopists for colonic or ileo-colonic Crohn's disease (CICD) with the "simple endoscopic score for Crohn's disease" (SES-CD), CD-related surgery patients with the Rutgeerts score, and ulcerative colitis (UC) with the Mayo score...
December 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29282640/high-incidence-of-recurrent-crohn-s-disease-following-colectomy-for-ulcerative-colitis-revealed-with-long-follow-up
#3
Steven Shamah, Judy Schneider, Burton I Korelitz
BACKGROUND AND AIMS: Ulcerative colitis (UC) patients with progression of their disease despite optimized medical therapy may warrant "curative" proctocolectomy with end ileostomy or ileo-anal pouch (IPAA) anastomosis. The aim of our study was to assess the incidence of later recurrent ileitis that lead to altering the initial diagnosis to Crohn's disease (CD). METHODS: A retrospective analysis was conducted on the inflammatory bowel disease database at Lenox Hill Hospital...
December 28, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29259383/double-balloon-enteroscopy-assisted-dilatation-avoids-surgery-for-small-bowel-strictures-a-systematic-review
#4
Judith E Baars, Ruben Theyventhiran, Patrick Aepli, Payal Saxena, Arthur J Kaffes
AIM: To evaluate the therapeutic role of double-balloon enteroscopy (DBE) in small bowel strictures and to propose a standard approach to small bowel strictures. METHODS: Systematic review of studies involving DBE in patients with small bowel strictures. Only studies limited to small bowel strictures were included and those with ileo-colonic strictures were excluded. RESULTS: In total 13 studies were included, in which 310 patients were dilated...
December 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29209121/fatal-gastrointestinal-histoplasmosis-15-years-after-orthotopic-liver-transplantation
#5
Nikita Agrawal, David Ej Jones, Jessica K Dyson, Tim Hoare, Sharon A Melmore, Stephanie Needham, Nick P Thompson
We report a case of ileo-colonic Histoplasmosis without apparent respiratory involvement in a patient who had previously undergone an orthotopic liver transplant (OLT) for primary biliary cholangitis 15 years earlier. The recipient lived in the United Kingdom, a non-endemic region for Histoplasmosis. However, she had previously lived in rural southern Africa prior to her OLT. The patient presented with iron deficiency anaemia, diarrhoea, abdominal pain and progressive weight loss. She reported no previous foreign travel, however, it later became known that following her OLT she had been on holiday to rural southern Africa...
November 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29203191/a-simple-neobladder-using-a-porcine-model-the-double-limb-u-pouch
#6
Ryan P Werntz, Poone Shoureshi, Kyle Gillis, Akash Kapadia, David Jiang, Christopher Amling, John M Barry
OBJECTIVE: To create a simple neobladder and determine whether the double limb U-Pouch (DLUP) has the same capacity and compliance as a Studer or Camey I neobladder. To develop an orthotopic diversion that can be applied to robotic surgery with laboratory data supporting the concept. MATERIALS AND METHODS: Kidneys, ureters, bladders, and small intestine were obtained from pigs at the time of scheduled autopsy after completion of institutionally approved investigational trauma protocols...
December 1, 2017: Urology
https://www.readbyqxmd.com/read/29184602/-giant-lithiasis-due-to-urinary-stasis-related-to-ileo-caecal-bladder
#7
Hamza Dergamoun, Zayd El Boukili El Makhoukhi
Bladder exstrophy is a malformation characterized by subumbilical anterior abdominal wall and anterior bladder wall deishence. It affects nearly 30.000-40.000 births per year, with a higher prevalence in boys. External continent urinary diversion creates a long-term outcome. However, it is not devoid of complications. We report the case of a 30-year old female patient who had undergone cystectomy with bladder replaced with ileo-caecal segment for bladder exstrophy 13 years earlier. She was followed up for 5 years and then lost to follow up...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29182898/reconnection-surgery-in-adult-post-operative-short-bowel-syndrome-100-cm-is-colonic-continuity-sufficient-to-achieve-enteral-autonomy-without-autologous-gastrointestinal-reconstruction-report-from-a-single-center-and-systematic-review-of-literature
#8
A Lauro, R Cirocchi, N Cautero, A Dazzi, D Pironi, F M Di Matteo, A Santoro, L Pironi, A D Pinna
A systematic bibliographic research concerning patients operated on for SBS was performed: inclusion criteria were adult age, reconnection surgery and SBS < 100 cm. Autologous gastrointestinal reconstruction represented an exclusion criteria. The outcomes of interest were the rate of total parenteral nutrition (TPN) independence and the length of follow-up (minimum 1 year) after surgery. We reviewed our experience from 2003 to 2013 with minimum 1-year follow-up, dealing with reconnection surgery in 13 adults affected by < 100 cm SBS after massive small bowel resection: autologous gastrointestinal reconstruction was not feasible...
July 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29098076/intraluminal-ileal-tumour-after-right-hemicolectomy-for-cancer-an-implantation-recurrence-or-a-new-cancer-a-case-report
#9
Marco Clementi, Sara Colozzi, Mario Schietroma, Federico Sista, Andrea Della Penna, Alessandro Chiominto, Stefano Guadagni
Introduction: Extra-anastomotic intraluminal recurrence of the colon cancer after curative surgery was rarely reported but intraluminal ileal relapse has not been described to date.We report a case of intraluminal ileal tumor arising after curative right hemicolectomy that could be ascribed to an implantation of exfoliated cancer cells. Case report: A 71-years old man was admitted with no metastatic stenotic adenocarcinoma of the hepatic flexure and submitted, without preoperative bowel preparation, to right hemicolectomy using a "no-touch" technique...
November 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29091335/outcome-of-restorative-proctocolectomy-with-ileo-anal-pouch-for-ulcerative-colitis-effect-of-changes-in-clinical-practice
#10
Adeline Germain, Anthony de Buck van Overstraeten, Albert Wolthuis, Marc Ferrante, Séverine Vermeire, Gert Van Assche, Andre D'Hoore
BACKGROUND: Surgery for ileal pouch-anal anastomosis (IPAA) has evolved over time, especially since the introduction of laparoscopy. OBJECTIVE: The aim of this retrospective study was to report the impact of surgical evolution on outcome over a period of 25 years. DESIGN AND PATIENTS: All patients with IPAA surgery for ulcerative colitis from 1990 to 2015 at the University Hospitals of Leuven were included. Patients were divided into 3 period arms (Period A:1990 - 1999; Period B: 2000 - 2009; Period C: 2010 - 2015)...
November 1, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29080993/a-surgical-solution-to-regain-bowel-continuity-following-an-extended-left-colectomy-reviving-and-extending-the-indication-for-a-flip-flop-procedure
#11
Ronen Ghinea, Shmuel Avital, Ephraim Katz, Baruch Shpitz, Ian White
BACKGROUND AND AIMS: Extended left hemicolectomy might be necessary for several indications. Once the resection is completed, it would be difficult or impossible to anastomose the transverse colon to the rectum due to the difficulty in mobilizing the transverse colon to reach for a tension-free rectal anastomosis. The aim of this report is to present the "Flip-Flop" technique to overcome this challenging situation. The procedure is based on a surgical technique published in the early 1960s to avoid permanent stoma after proctectomy and consists of changing the location of the right colon to reach the rectum...
October 28, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29079372/positive-guaiac-and-bloody-stool-are-poor-predictors-of-intussusception
#12
Amir A Kimia, Scotty Williams, Peter N Hadar, Assaf Landschaft, John Porter, Richard G Bachur
BACKGROUND: Currant jelly stool is a late manifestation of intussusception and is rarely seen in clinical practice. Other forms of GI bleeding have not been thoroughly studied and little is known about their respective diagnostic values. OBJECTIVE: To assess the predictive value of GI bleeding (positive guaiac test, bloody stool and rectal bleeding in evaluation of intussusception. METHODS: We performed a retrospective cross-sectional study cohort of all children, ages 1month-6years of age, who had an abdominal ultrasound obtained evaluating for intussusception over 5year period...
October 18, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29074486/metabolic-markers-of-protein-maldigestion-after-a-15-n-test-meal-in-minipigs-with-pancreatic-exocrine-insufficiency
#13
Florence Mary, Anne Moesseler, Nadezda Khodorova, Angélique Foucault-Simonin, Robert Benamouzig, Daniel Tomé, Peter Colin Gregory, Claire Gaudichon
The effect of pancreatic exocrine insufficiency (PEI) on protein malabsorption is little documented, partly due to methodological barriers. We aimed to validate biomarkers of protein malabsorption using a (15)N test meal in a minipig model of PEI. Six pancreatic duct-ligated minipigs were used as a model of PEI and four non-operated animals as a control. All animals were equipped with an ileo-caecal re-entrant cannula. Minipigs were given a test meal containing (15)N casein. The PEI animals repeated the test 3 times, in the absence of any pancreatic enzymes, or after pancreatic substitution at 2 levels (A or B: 7500 or 75,000 (lipase) and 388 or 3881 (protease) FIP U)...
October 26, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29067041/paediatric-inflammatory-bowel-disease-clinical-presentation-and-disease-location
#14
Danish Abdul Aziz, Maryum Moin, Atif Majeed, Kamran Sadiq, Abdul Gaffar Biloo
OBJECTIVE: To determine different clinical presentationsand disease location demarcatedby upper and lower gastrointestinal endoscopyand relevant histopathologyin children diagnosed with inflammatory bowel disease (IBD). METHODS: This is 5 years (2010 to 2015) retrospective studyconducted at the Aga Khan University Hospitalenrolling65admitted children between 6 months to 15years from either gender, diagnosed with IBD on clinical presentation, endoscopy and biopsy...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29043605/liquid-nanosize-emulsion-filled-enteric-coated-capsules-for-colon-delivery-of-immunosuppressant-peptide
#15
Sumit Sharma, Vivek Ranjan Sinha
Present study aims at solubilizing slightly water-soluble peptide into a nanosize emulsion which is filled into a hard gelatin capsule in the form of preconcentrate. Further, liquid-filled capsule was dip-coated with ethyl cellulose and Eudragit S100 for colon targeting. An in vitro release profile was studied for selected formulations, i.e., Formulation A (5 mg ethyl cellulose and 40 mg Eudragit S100), Formulation B (10 mg ethyl cellulose and 30 mg Eudragit S100), and Formulation C (10 mg ethyl cellulose and 20 mg Eudragit S100)...
October 17, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/29032780/prediction-of-the-amino-acid-digestibility-of-legume-seeds-in-growing-pigs-a-meta-analysis-approach
#16
F Messad, M P Létourneau-Montminy, E Charbonneau, D Sauvant, F Guay
On pig farms, a high proportion of the cost of production comes from feed costs. However, the use of alternative ingredients such as legume seeds may help to reduce this cost. In fact, legume seeds are an important source of essential amino acids (EAA) and can therefore be an alternative to oilseed meals. However, the accurate use of these legume seeds requires a precise knowledge of the standardized ileal digestibility (SID) of EAA, which may vary depending on its botanical variety. A meta-analysis was performed on a database compiling data from 41 studies published between 1981 and 2013 and 178 dietary treatments...
October 16, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28971180/an-infrequent-case-of-intussusception-caused-by-gastrointestinal-stromal-tumor-in-an-adult-patient
#17
Mehmet Mahir Fersahoglu, Ayse Tuba Fersahoglu, Nuriye Esen Bulut, Burcu Seher Anil Narin, Sinan Tezer
Intussusception may occur anywhere in the gastrointestinal system. Unlike its idiopathic childhood counterpart, it is uncommon during adult life and a definitive cause is usually found; almost half of cases develop with malignancy. Gastrointestinal stromal tumors (GIST) originate from interstitial Cajal cells of the gastrointestinal tract. They more frequently occur in the stomach and small intestines, and often grow extraluminally, making it unlikely to cause an obstruction or bleeding. Presently described is an unusual instance of ileo-ileal intussusception due to GIST...
2017: Northern Clinics of Istanbul
https://www.readbyqxmd.com/read/28970773/a-case-of-compound-intussusceptions-in-a-nigerian-child-a-rare-finding-in-a-common-disease
#18
K I Egbuchulem, T A Lawal, M C Nweke, A O Adeoye
Intussusception is the most common, non-congenital, cause of intestinal obstruction in infants. There are various patterns of intussusception seen in children with the most common being ileo-colic variety. Compound intussusception in which intussusception involves more than one non-adjacent segment is a rare finding in the literature and it can be associated with worse morbidity than typically occurs, especially in a region where delayed presentation is a major contributor to morbidity and mortality in the treatment of intestinal obstruction...
June 2017: Annals of Ibadan Postgraduate Medicine
https://www.readbyqxmd.com/read/28965167/laparoscopic-reversal-of-the-biliopancreatic-diversion-with-duodenal-switch-a-step-by-step-video-case
#19
Hamzeh M Halawani, Gintaras Antanavicius
BACKGROUND: Despite the success of the Biliopancreatic Diversion with Duodenal Switch procedure (BPD-DS) in weight loss and comorbidities resolution, reversal of BPD-DS is necessary in 0.2-0.6% of BPD-DS cases for vitamin, protein, and other micronutrient deficiencies. Different techniques are available to reverse the malabsorptive component of the BPD-DS. METHODS: A retrospective chart review for a 37-year-old female patient who presented with lower leg edema and signs of malnutrition 5 years after a BPD/DS...
December 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28903846/ileocolonic-basidiobolomycosis-in-a-child-an-unusual-fungal-infection
#20
Anjum Saeed, Ahmed Alsarkhy, Mona Al Asmi, Mohammad El Mouzan, Yasin Hamid, Asaad Assiri
Systemic basidiobolomycosis is a rare fungal infection caused by Basidiobolus rararum (B. rararum). The clinical presentation is non-specific and is similar to many gastrointestinal conditions such as Crohn's disease (CD). The most consistent findings of basidiobolomycosis are recurrent abdominal pain, weight loss, fever and peripheral eosinophilia. Most of the patients are diagnosed on surgical resection of the involved region along with compatible histopathological findings like transmural inflammation, granulomas with eosinophilic infiltration (Splendore-Hoeppli phenomenon) and more specifically detection of fungal hyphae on fungal stains...
August 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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