keyword
https://read.qxmd.com/read/38463355/development-of-a-new-cox-model-for-predicting-long-term-survival-in-hepatitis-cirrhosis-patients-underwent-transjugular-intrahepatic-portosystemic-shunts
#21
JOURNAL ARTICLE
Yi-Fan Lv, Bing Zhu, Ming-Ming Meng, Yi-Fan Wu, Cheng-Bin Dong, Yu Zhang, Bo-Wen Liu, Shao-Li You, Sa Lv, Yong-Ping Yang, Fu-Quan Liu
BACKGROUND: Transjugular intrahepatic portosystemic shunt (TIPS) placement is a procedure that can effectively treat complications of portal hypertension, such as variceal bleeding and refractory ascites. However, there have been no specific studies on predicting long-term survival after TIPS placement. AIM: To establish a model to predict long-term survival in patients with hepatitis cirrhosis after TIPS. METHODS: A retrospective analysis was conducted on a cohort of 224 patients who underwent TIPS implantation...
February 27, 2024: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38463113/a-rare-delayed-onset-of-esophageal-varices-and-portal-vein-thrombosis-in-a-ten-year-old-patient-following-umbilical-vein-catheterization
#22
Qusay Abdoh, Abdalaziz Darwish, Mohammad Alnees, Mahdi Awwad, Duha Najajra, Mai Alsadi, Maysa Alawneh
INTRODUCTION AND SIGNIFICANCE: Portal vein thrombosis (PVT) is not commonly observed in patients, particularly those who have gone through neonatal intensive care unit (NICU) stays and had umbilical catheters. Although PVT can potentially cause hypertension and gastrointestinal bleeding it is highly unusual for this condition to manifest during childhood. CASE PRESENTATION: The authors present a case of a 10-year-old child who developed portal hypertension, esophageal varices, and multiple thrombophilia associated mutations...
March 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38462957/development-and-validation-of-a-scoring-system-for-in-hospital-mortality-following-band-ligation-in-esophageal-variceal-bleeding
#23
JOURNAL ARTICLE
Chikamasa Ichita, Tadahiro Goto, Yohei Okada, Haruki Uojima, Masao Iwagami, Akiko Sasaki, Sayuri Shimizu
OBJECTIVES: We aimed to develop and validate a simple scoring system to predict in-hospital mortality after endoscopic variceal ligation (EVL) for esophageal variceal bleeding. METHODS: Data from a 13-year study involving 46 Japanese institutions were split into development (initial 7 years) and validation (last 6 years) cohorts. The study subjects were patients hospitalized for esophageal variceal bleeding and treated with EVL. Variable selection was performed using least absolute shrinkage and selection operator regression, targeting in-hospital all-cause mortality as the outcome...
March 11, 2024: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://read.qxmd.com/read/38462695/editorial-shorter-course-of-intravenous-terlipressin-in-acute%C3%A2-variceal-bleeding-the-promise-controversies-and-future%C3%A2-directions
#24
EDITORIAL
Yu Jun Wong, Juan G Abraldes
No abstract text is available yet for this article.
April 2024: Alimentary Pharmacology & Therapeutics
https://read.qxmd.com/read/38462689/editorial-shorter-course-of-intravenous-terlipressin-in-acute-variceal-bleeding-the-promise-controversies-and-future-directions-author-s-reply
#25
EDITORIAL
Sagnik Biswas, Manas Vaishnav, Shalimar
No abstract text is available yet for this article.
April 2024: Alimentary Pharmacology & Therapeutics
https://read.qxmd.com/read/38454245/can-endothelin-1-levels-in-patients-with-esophageal-variceal-bleeding-at-admission-predict-rebleeding-within-5-days
#26
JOURNAL ARTICLE
Shaker Wagih Shaltout, A E Messery, Ahmed Elshabrawi, Ahmed I Amin, Mostafa H Elshennawy, Metwaly Ibrahim Mortada, Walid ElSherbiny, Hatem Elalfy, Dina Elhammady
BACKGROUND/AIMS: Portal hypertension complicating liver cirrhosis is associated with vascular resistance, possibly due to overexpression of humoral vasoconstrictors, including endothelin. The study aimed to evaluate the efficacy of serum endothelin-1 levels as a noninvasive predictor of early esophageal rebleeding (within 5 days) following endoscopic treatment. MATERIALS AND METHODS: Of the patients presented to the endoscopy unit at Mansoura University Hospital, 50 patients were chosen for this study on the basis of endoscopically proven acute esophageal variceal bleeding consequent to hepatitis C viral infection complicated by liver cirrhosis and portal hypertension...
February 2024: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://read.qxmd.com/read/38445926/safety-and-efficacy-of-transjugular-intrahepatic-portosystemic-shunts-vs-endoscopic-band-ligation-plus-propranolol-in-patients-with-cirrhosis-with-portal-vein-thrombosis-a-systematic-review-and-meta-analysis
#27
REVIEW
Mahmoud Saad Berengy, Elsayed Mohamed Abd El-Hamid Hassan, Amal H Ibrahim, Eman F Mohamed
BACKGROUND: This systematic review and meta-analysis aimed to assess the efficacy and safety of transjugular intrahepatic portosystemic shunts (TIPS) against the combined treatment of endoscopic band ligation (EBL) and propranolol in managing patients with cirrhosis diagnosed with portal vein thrombosis (PVT). METHODS: A literature search from inception to September 2023 was performed using MEDLINE, the Cochrane Library, Web of Science, and Scopus. Independent screening, data extraction, and quality assessment were performed...
March 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38444690/improving-outcomes-in-hepatorenal-syndrome-acute-kidney-injury-with-early-diagnoses-and-implementation-of-approved-treatment-regimens
#28
JOURNAL ARTICLE
Nikolaos T Pyrsopoulos, David Bernstein, Marcelo Kugelmas, Emily J Owen, K Rajender Reddy, Nancy Reau, Sammy Saab, Hani M Wadei
Decompensated cirrhosis, defined by the overt manifestations of liver failure and portal hypertension (eg, ascites, hepatic encephalopathy, variceal bleeding), is the inflection point associated with increased morbidity and mortality in chronic liver disease. Acute kidney injury in the setting of cirrhosis (hepatorenal syndrome-acute kidney injury [HRS-AKI]) is a severe and often fatal complication. The goals of treatment of HRS-AKI are to reverse renal failure and prolong survival in these critically ill patients or perhaps to allow the transplant team to complete the pretransplant evaluation and bridge the patient to transplant...
December 2023: Gastroenterology & Hepatology
https://read.qxmd.com/read/38444185/clinical-outcomes-of-variceal-and-non-variceal-upper-gastrointestinal-bleeding-in-cirrhosis-patients-in-singapore
#29
JOURNAL ARTICLE
Garrett Kang, Le Shaun Ang, Wen Hui Leia Teo, Yu Wei Cheryl Huang, Venkataraman Narayan, Andrew Boon Eu Kwek, Tiing Leong Ang, Yu Jun Wong
No abstract text is available yet for this article.
March 6, 2024: Singapore Medical Journal
https://read.qxmd.com/read/38438672/prognosis-of-lspd-versus-tips-for-the-treatment-of-esophagogastric-variceal-bleeding-in-cirrhosis
#30
JOURNAL ARTICLE
Biao Chen, Jingxuan Wang, Weiyong Sheng, Bingqing Ma, Peng Xu, Xing Cheng, Weiyi Cheng, Chengjun Cai, Guoliang Wang, Wenming Pan, Chidan Wan, Chuansheng Zheng, Ping Cheng, Jinxiang Zhang
BACKGROUND: This study aimed to compare postoperative complications in patients with esophagogastric variceal bleeding (EVB) who underwent laparoscopic splenectomy combined with pericardial devascularization (LSPD) versus transjugular intrahepatic portosystemic shunt (TIPS) procedures. METHODS: A retrospective collection of medical records was conducted from January 2014 to May 2020 at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology...
March 4, 2024: Surgical Endoscopy
https://read.qxmd.com/read/38436701/value-of-multidetector-computed-tomography-angiography-in-severe-non-variceal-upper-gastrointestinal-bleeding-a-retrospective-study-in-a-referral-bleeding-unit
#31
JOURNAL ARTICLE
Marco Di Serafino, Alberto Martino, Francesco Manguso, Roberto Ronza, Francesco Paolo Zito, Francesco Giurazza, Luca Pignata, Luigi Orsini, Raffaella Niola, Luigia Romano, Giovanni Lombardi
BACKGROUND: Non-variceal upper gastrointestinal bleeding is a common gastroenterological emergency associated with significant morbidity and mortality. Upper gastrointestinal endoscopy is currently recommended as the gold standard modality for both diagnosis and treatment. As historically played a limited role in the diagnosis of acute non-variceal upper gastrointestinal bleeding, multidetector-row computed tomography angiography is emerging as a promising tool in the diagnosis of non-variceal upper gastrointestinal bleeding, especially for severe cases...
March 4, 2024: Abdominal Radiology
https://read.qxmd.com/read/38425713/esophageal-squamous-cell-carcinoma-complicated-with-varices-successfully-treated-by-endoscopic-injection-sclerotherapy-and-argon-plasma-coagulation-a-case-report
#32
Sayuri Watanabe, Takuto Hikichi, Takumi Yanagita, Jun Nakamura, Minami Hashimoto, Tsunetaka Kato, Ryoichiro Kobashi, Yuichi Waragai, Masao Kobayakawa, Hiromasa Ohira
Treatment guidelines for esophageal squamous cell carcinoma (ESCC) with concomitant esophageal varices (EVs), which increase the risk of bleeding, are unavailable. A 66-year-old man with a history of total gastrectomy was admitted to the hospital owing to hematemesis. Emergency upper gastrointestinal endoscopy revealed variceal bleeding near the anastomosis between the esophagus and jejunum, and endoscopic clipping stopped the bleeding. Upper gastrointestinal endoscopy following hemostasis revealed four EVs and a two-thirds ESCC circumference...
April 2024: DEN Open
https://read.qxmd.com/read/38423766/trends-of-hospitalisation-among-new-admission-inpatients-with-oesophagogastric-variceal-bleeding-in-cirrhosis-from-2014-to-2019-in-the-affiliated-hospital-of-southwest-medical-university-a-single-centre-time-series-analysis
#33
JOURNAL ARTICLE
Jieyu Peng, Xinyi Zeng, Shu Huang, Han Zhang, Huifang Xia, Kang Zou, Wei Zhang, Xiaomin Shi, Lei Shi, Xiaolin Zhong, Muhan Lü, Yan Peng, Xiaowei Tang
OBJECTIVES: This study aimed to assess the internal law and time trend of hospitalisation for oesophagogastric variceal bleeding (EGVB) in cirrhosis and develop an effective model to predict the trend of hospitalisation time. DESIGN: We used a time series covering 72 months to analyse the hospitalisation for EGVB in cirrhosis. The number of inpatients in the first 60 months was used as the training set to establish the autoregressive integrated moving average (ARIMA) model, and the number over the next 12 months was used as the test set to predict and observe their fitting effect...
February 29, 2024: BMJ Open
https://read.qxmd.com/read/38420152/interactive-training-with-a-novel-simulation-model-for-upper-gastrointestinal-endoscopic-hemostasis-improves-trainee-technique-and-confidence
#34
JOURNAL ARTICLE
Takeshi Kanno, Yutaro Arata, Eric Greenwald, Paul Moayyedi, Suguo Suzuki, Yutaka Hatayama, Masahiro Saito, Xiaoyi Jin, Waku Hatta, Kaname Uno, Naoki Asano, Akira Imatani, Yutaka Kagaya, Tomoyuki Koike, Atsushi Masamune
Background and study aims Endoscopic hemostasis is a life-saving procedure for gastrointestinal bleeding; however, training for it is often performed on real patients and during urgent situations that put patients at risk. Reports of simulation-based training models for endoscopic hemostasis are scarce. Herein, we developed a novel simulator called "Medical Rising STAR-Ulcer type" to practice endoscopic hemostasis with hemoclips and coagulation graspers. This study aimed to evaluate the reproducibility of the clinical difficulty of this model and the effectiveness of simulation-based training for clipping hemostasis...
February 2024: Endoscopy International Open
https://read.qxmd.com/read/38414583/evaluation-of-the-efficacy-and-safety-of-endoscopic-band-ligation-in-the-treatment-of-bleeding-from-mild-to-moderate-gastric-varices-type-1
#35
JOURNAL ARTICLE
Yue Deng, Ya Jiang, Tong Jiang, Ling Chen, Hai-Jun Mou, Bi-Guang Tuo, Guo-Qing Shi
BACKGROUND: According to practice guidelines, endoscopic band ligation (EBL) and endoscopic tissue adhesive injection (TAI) are recommended for treating bleeding from esophagogastric varices. However, EBL and TAI are known to cause serious complications, such as hemorrhage from dislodged ligature rings caused by EBL and hemorrhage from operation-related ulcers resulting from TAI. However, the optimal therapy for mild to moderate type 1 gastric variceal hemorrhage (GOV1) has not been determined...
February 7, 2024: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/38409879/evaluation-of-potential-hepatic-recompensation-criteria-in-patients-with-pbc-and-decompensated-cirrhosis
#36
JOURNAL ARTICLE
Benedikt Silvester Hofer, Lukas Burghart, Emina Halilbasic, Benedikt Simbrunner, Oleksandr Petrenko, Mattias Mandorfer, Albert Friedrich Stättermayer, Michael Trauner, Thomas Reiberger
BACKGROUND: Aetiological therapy improves liver function and may enable hepatic recompensation in decompensated cirrhosis. AIMS: We explored the potential for recompensation in patients with decompensated primary biliary cholangitis (PBC) - considering a biochemical response to ursodeoxycholic acid (UDCA) according to Paris-II criteria as a surrogate for successful aetiological treatment. METHODS: Patients with PBC were retrospectively included at the time of first decompensation...
February 26, 2024: Alimentary Pharmacology & Therapeutics
https://read.qxmd.com/read/38404733/clinical-features-of-extrahepatic-portal-vein-obstruction-myeloproliferative-neoplasms-eliminate-hypersplenic-hematologic-changes-in-extrahepatic-portal-vein-obstruction
#37
JOURNAL ARTICLE
Tetsuya Shimizu, Hiroshi Yoshida, Nobuhiko Taniai, Masato Yoshioka, Yoichi Kawano, Akira Matsushita, Junji Ueda, Takuma Iwai, Takahiro Murokawa, Takashi Ono, Akira Hamaguchi
Extrahepatic portal vein obstruction (EHPVO) is a rare disease. Most EHPVO patients are usually referred to a gastroenterologist for intestinal bleeding and hypersplenic thrombocytopenia; however, hypercoagulative diseases may be occult in these patients and require anticoagulation. The purpose of this study was to elucidate the clinical characteristics of EHPVO. We conducted a retrospective analysis of the hospital database, evaluating the medical records of 15 patients (7 males, 8 females, mean age of onset 42...
February 2024: Intractable & Rare Diseases Research
https://read.qxmd.com/read/38395484/variceal-and-nonvariceal-upper-gastrointestinal-bleeding-refractory-to-endoscopic-management-indications-and-role-of-interventional-radiology
#38
REVIEW
Ece Meram, Elliott Russell, Orhan Ozkan, Mark Kleedehn
For over 60 years, diagnostic and interventional radiology have been heavily involved in the evaluation and treatment of patients presenting with gastrointestinal bleeding. For patients who present with upper GI bleeding and have a contraindication to endoscopy or have an unsuccessful attempt at endoscopy for identifying or controlling the bleeding, interventional radiology is often consulted for evaluation and consideration of catheter-based intervention.
April 2024: Gastrointestinal Endoscopy Clinics of North America
https://read.qxmd.com/read/38395482/endoscopic-treatment-of-acute-esophageal-and-gastric-variceal-bleeding
#39
REVIEW
Kendra Jobe, Zachary Henry
Acute variceal bleeding is a serious complication of portal hypertension. This most often manifests as bleeding from esophageal varices. Although less likely to occur, bleeding from gastric varices is usually more severe. The best endoscopic management for acute esophageal variceal bleeding is band ligation and this often proves to be definitive therapy for these patients. For gastric variceal bleeding, the best endoscopic therapy is endoscopic cyanoacrylate injection but this can be cumbersome to perform and is not a readily available resource at most centers in the United States...
April 2024: Gastrointestinal Endoscopy Clinics of North America
https://read.qxmd.com/read/38395481/the-role-of-endoscopy-for-primary-and-secondary-prophylaxis-of-variceal-bleeding
#40
REVIEW
Andrew S Ma, Paul J Thuluvath
Cirrhosis is associated with a high morbidity and mortality. One of the most serious and unpredictable complication of cirrhosis, with a high mortality rate, is bleeding from esophagogastric varices. Endoscopic screening of varices followed by primary prophylactic treatment with beta blockers or band ligation in the presence of large esophageal varices will reduce the variceal bleeding rates and thereby reduce mortality risks in those with advanced cirrhosis. There is a paucity of data on primary prophylaxis of gastric varices but secondary prophylaxis includes glue injection, balloon-occluded retrograde transvenous obliteration, or transjugular intrahepatic portosystemic shunting with coil embolization...
April 2024: Gastrointestinal Endoscopy Clinics of North America
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