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https://www.readbyqxmd.com/read/27936388/nanoliposome-encapsulated-anesthetics-for-local-anesthesia-application
#1
REVIEW
Sepideh Vahabi, Ali Eatemadi
The systemic administration of opioids leads to potentially severe and undesirable and side effects like sedation and drowsiness, vomiting and nausea, allergies, respiratory depression, and neutrophil dysfunction. The application of nanotechnology in medical field has drawn a great attention in recent times. Several treatments available are tedious and expensive. Application of nanotechnology brings about faster cure and cost effectiveness. Nanoliposomes are one of the widely used names for nanoparticles used in medicine...
December 6, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27936053/predicting-30-day-readmissions-in-an-asian-population-building-a-predictive-model-by-incorporating-markers-of-hospitalization-severity
#2
Lian Leng Low, Nan Liu, Sijia Wang, Julian Thumboo, Marcus Eng Hock Ong, Kheng Hock Lee
BACKGROUND: To reduce readmissions, it may be cost-effective to consider risk stratification, with targeting intervention programs to patients at high risk of readmissions. In this study, we aimed to derive and validate a prediction model including several novel markers of hospitalization severity, and compare the model with the LACE index (Length of stay, Acuity of admission, Charlson comorbidity index, Emergency department visits in past 6 months), an established risk stratification tool...
2016: PloS One
https://www.readbyqxmd.com/read/27936028/cost-effectiveness-of-screening-colonoscopy-depends-on-adequate-bowel-preparation-rates-a-modeling-study
#3
James Kingsley, Siddharth Karanth, Frances Lee Revere, Deepak Agrawal
BACKGROUND: Inadequate bowel preparation during screening colonoscopy necessitates repeating colonoscopy. Studies suggest inadequate bowel preparation rates of 20-60%. This increases the cost of colonoscopy for our society. AIM: The aim of this study is to determine the impact of inadequate bowel preparation rate on the cost effectiveness of colonoscopy compared to other screening strategies for colorectal cancer (CRC). METHODS: A microsimulation model of CRC screening strategies for the general population at average risk for CRC...
2016: PloS One
https://www.readbyqxmd.com/read/27935971/costs-of-care-of-hiv-infected-children-initiating-lopinavir-ritonavir-based-antiretroviral-therapy-before-the-age-of-two-in-cote-d-ivoire
#4
Sophie Desmonde, Divine Avit, Junie Petit, Madeleine Amorissani Folquet, Francois Tanoh Eboua, Clarisse Amani Bosse, Evelyne Dainguy, Véronique Mea, Marguerite Timite-Konan, Sylvie Ngbeché, Andrea Ciaranello, Valeriane Leroy
OBJECTIVES: To access the costs of care for Ivoirian children before and after initiating LPV/r-based antiretroviral therapy (ART) before the age of two. METHODS: We assessed the direct costs of care for all HIV-infected children over the first 12 months on LPV/r-based ART initiated <2 years of age in Abidjan. We recorded all drug prescriptions, ART and cotrimoxazole prophylaxis delivery, medical analyses/examinations and hospital admissions. We compared these costs to those accrued in the month prior to ART initiation...
2016: PloS One
https://www.readbyqxmd.com/read/27935933/comprehensive-diabetes-and-non-communicable-disease-educator-in-the-low-resource-settings
#5
M D Bhattarai
The role of self-management education in diabetes and other major non-communicable diseases is clearly evident. To take care of and educate people with diabetes and other major NCD under the supervision of medical professionals and for education of other health care professionals, Comprehensive Diabetes and NCD Educators are needed in the routine service in peripheral health clinics and hospitals. The areas of training of CDNCD educator should match with the cost-effective interventions for diabetes and other major NCD that are feasible and planned for implementation in primary care in the low resource settings...
April 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27935536/evaluation-of-a-12-month-pilot-of-long-term-and-temporary-assisted-peritoneal-dialysis
#6
Micheli U Bevilacqua, Linda Turnbull, Sushila Saunders, Lee Er, Helen Chiu, Penny Hill, Rajinder S Singh, Adeera Levin, Michael A Copland, Abeed Jamal, Catherine Brumby, Orla Dunne, Paul A Taylor
♦ Background: Peritoneal dialysis (PD) is challenging for patients with functional limitations, and assisted PD can support these patients, but previous reports of assisted PD have not examined the role of temporary assisted PD and had difficulty identifying adequate comparator cohorts. ♦ Methods: Peritoneal Dialysis Assist (PDA), a 12-month pilot of long-term and temporary assisted PD was completed in multiple PD centers in British Columbia, Canada. Continuous cycler PD (CCPD) patients were identified for PDA by standardized criteria, and service could be long-term or temporary/respite...
December 1, 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27933568/healthcare-costs-among-patients-with-heart-failure-a-comparison-of-costs-between-matched-decedent-and-survivor-cohorts
#7
Engels N Obi, Jason P Swindle, Stuart J Turner, Patricia A Russo, Aylin Altan
INTRODUCTION: Prior research suggests increased costs during the final months of life, yet little is known about healthcare cost differences between patients with heart failure (HF) who die or survive. METHODS: A retrospective claims study from a large US health plan [commercial and Medicare Advantage with Part D (MAPD)] was conducted. Patients were ≥18 years old with two non-inpatient or one inpatient claim(s) with HF diagnosis code(s). The earliest HF claim date during 1 January 2010-31 December 2011 was the index date...
December 8, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27933399/implementation-of-clinical-decision-support-in-young-children-with-acute-gastroenteritis-a-randomized-controlled-trial-at-the-emergency-department
#8
Dorien Geurts, Evelien de Vos-Kerkhof, Suzanne Polinder, Ewout Steyerberg, Johan van der Lei, Henriëtte Moll, Rianne Oostenbrink
: Acute gastroenteritis (AGE) is one of the most frequent reasons for young children to visit emergency departments (EDs). We aimed to evaluate (1) feasibility of a nurse-guided clinical decision support system for rehydration treatment in children with AGE and (2) the impact on diagnostics, treatment, and costs compared with usual care by attending physician. A randomized controlled trial was performed in 222 children, aged 1 month to 5 years at the ED of the Erasmus MC-Sophia Children's hospital in The Netherlands ( 2010-2012)...
December 8, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27933383/the-burden-of-rotator-cuff-surgery-in-italy-a-nationwide-registry-study
#9
Umile Giuseppe Longo, Giuseppe Salvatore, Giacomo Rizzello, Alessandra Berton, Mauro Ciuffreda, Vincenzo Candela, Vincenzo Denaro
PURPOSE: This study aimed to estimate the yearly number of RC surgeries in Italy, a country with universal access to healthcare for its population, from 2001 to 2014, based on official information source as hospitalization records. A secondary aim was to explore geographical variation in equity in access to RC surgery between three macroregions of Italy (North, Center and South). A tertiary aim was to perform statistical projections of the number of RC procedure volumes and rates on the basis of data from 2001 to 2014...
December 8, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27933153/improving-pneumococcal-vaccination-rates-of-medical-inpatients-in-urban-nepal-using-quality-improvement-measures
#10
Allison Bock, Kathan Chintamaneni, Lisa Rein, Tifany Frazer, Gyan Kayastha, Theodore MacKinney
Streptococcus pneumoniae infection is associated with high morbidity and mortality in low income countries. In Nepal, there is a high lung disease burden and incidence of pneumonia due to multiple factors including indoor air pollution, dust exposure, recurrent infections, and cigarette smoking. Despite the ready availability of effective pneumococcal vaccines (PNV), vaccine coverage rates remain suboptimal globally. Quality Improvement (QI) principles could be applied to improve compliance, but it is a virtually new technology in Nepal...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27933145/ensuring-timely-thromboprophylaxis-on-a-medical-assessment-unit
#11
Oluwatosin Akinbobuyi, Louise Shalders, Tim Nokes
The Department of Health has defined hospital acquired venous thromboembolism (VTE) as any VTE event occurring within 90 days of hospital admission or surgery. (1) Hospital acquired thrombosis (HAT) is common during and after hospital admission and is considered a major patient safety issue. Current NICE guideline (CG 92) 2010, recommends that medical patients assessed at risk of VTE should have pharmacological prophylaxis commenced as soon as possible after risk assessment has been completed and continued until the patient is no longer at increased risk of VTE...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27933144/a-project-to-improve-the-management-of-patients-on-warfarin-in-a-primary-care-setting-through-the-introduction-of-a-poc-analysis
#12
Thore Karlsson
When noticed that patients commonly misunderstood their warfarin prescriptions when they were given by telephone. We found that the average TIR (time in range) (the relative time period the patients PT-INR value was in the therapeutic range) for patients decreased, and we noticed that the numbers of incidents increased. We made several interventions over a period of close to three years (2010-2012) to improve the quality of care, increase patients' TIRs, and decrease incidents. The interventions included; taking extra care when speaking to patients about their warfarin prescriptions on the phone and using an express mail delivery system to make sure patients got their letters in time...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27933020/feasibility-of-group-schema-therapy-for-outpatients-with-severe-borderline-personality-disorder-in-germany-a-pilot-study-with-three-year-follow-up
#13
Eva Fassbinder, Maren Schuetze, Annika Kranich, Valerija Sipos, Fritz Hohagen, Ida Shaw, Joan Farrell, Arnoud Arntz, Ulrich Schweiger
Borderline Personality Disorder (BPD) is a severe, challenging to treat mental disorder. Schema therapy (ST) as an individual therapy has been proven to be an effective psychological treatment for BPD. A group format of ST (GST) has been developed and evaluated in a randomized controlled trial in the United States and piloted in The Netherlands. These results suggest that GST speeds up and amplifies treatment effects of ST and might reduce delivery costs. However, feasibility in the German health care system and with BPD patients with high BPD severity and comorbidity, and frequent hospitalization, has not been tested to date...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27932775/-experience-in-transumbilical-endoscopic-surgery-diagnosis-for-3-cases-of-pseudomyxoma-peritonei
#14
Li Tian, Anliu Tang, Fen Liu, Shourong Shen, Xiaoyan Wang
Three patients of pseudomyxoma peritonei who were diagnozed by transumbilical endoscopic surgery (TUES) were reviewed retrospectively from September 2014 to November 2014. Three cases of ascites patients underwent TUES were diagnozed as pseudomyxoma peritonei. All operations were successful. No open surgery or laparoscopic surgery was required. The mean operative time was (45±16) min; the mean intraoperative blood loss was 510 mL; the mean hospital stay time was 3 days. During the follow up of 911 months, no obvious scar was observed...
November 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27932381/improving-the-efficiency-of-care-for-pediatric-patients-hospitalized-with-asthma
#15
Kathleen W Bartlett, Victoria M Parente, Vanessa Morales, Jillian Hauser, Heather S McLean
BACKGROUND: Asthma exacerbations are a leading cause of hospitalization among children. Despite the existence of national pediatric asthma guidelines, significant variation in care persists. At Duke Children's Hospital, we determined that our average length of stay (ALOS) and cost for pediatric asthma admissions exceeded that of our peers. Our aim was to reduce the ALOS of pediatric patients hospitalized with asthma from 2.9 days to 2.6 days within 12 months by implementing an asthma pathway within our new electronic health record...
December 8, 2016: Hospital Pediatrics
https://www.readbyqxmd.com/read/27932252/changes-in-primary-care-provision-in-turkey-a-comparison-of-1993-and-2012
#16
Mehmet Akman, Sibel Sakarya, Mehmet Sargın, İlhami Ünlüoğlu, Memet Taşkın Eğici, Wienke G W Boerma, Willemijn L A Schäfer
Since the early 1990s, the primary care system in Turkey has undergone fundamental changes. In the first decade of the millennium family doctor scheme was introduced to the Turkish primary care sector and the name of the primary care doctors (PCDs) changed from "general practitioner" (GP) to "family doctor" (FD). This study aims to give an insight into those changes and to compare the service profiles of PCDs in 1993 and 2012. Data, based on cross sectional surveys among Turkish doctors working in primary care are derived from the 1993 European GP Task Profile study (n=199) and the 2012 Quality and Costs of Primary Care in Europe (QUALICOPC) study (n=299)...
December 5, 2016: Health Policy
https://www.readbyqxmd.com/read/27932005/estimating-community-level-costs-of-preterm-birth
#17
E S Hall, J M Greenberg
OBJECTIVES: To develop generalizable methods for estimating the economic impact of preterm birth at the community level on initial hospital expenditures, educational attainment and lost earnings as well as to estimate potential savings associated with reductions in preterm birth. STUDY DESIGN: The retrospective, population-based analysis used vital statistics and population demographics from Hamilton County, Ohio, USA, in 2012. METHODS: We adjusted previously reported, mean initial hospital cost estimates (stratified by each week of gestation) to 2012 dollars using national cost-to-charge ratios...
December 2016: Public Health
https://www.readbyqxmd.com/read/27931338/health-care-provider-perspectives-on-tuberculosis-care-for-foreign-born-populations-in-new-york-city
#18
J R Zelnick, M R O'Donnell, S D Ahuja, A Chua, J Sullivan Meissner
BACKGROUND: Tuberculosis (TB) in foreign-born patients is a key determinant of TB epidemiology in low-burden settings. In New York City (NYC), foreign-born TB populations are heterogeneous and face diverse challenges in accessing care. OBJECTIVE: To characterize barriers and facilitators to health care services and identify potential mechanisms to improve TB care for foreign-born patients in NYC. DESIGN: Semi-structured interviews with health care providers identified through the NYC TB registry and snowball sampling...
December 2016: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/27931114/factors-associated-with-compliance-in-submitting-24-hour-urine-collections-in-an-underserved-community
#19
Eric Ghiraldi, Madhumitha Reddy, Tianyu Li, Andrew C Lawler, Justin Friedlander
PURPOSE: Patients living in underserved areas do regularly express an interest in stone prevention; however, factors limiting participation, aside from obvious cost considerations, are largely unknown. To better understand factors associated with compliance with submitting 24-hour urine collections, we reviewed our patient experience at the kidney stone clinic at a hospital that provides care for an underserved urban community. MATERIALS AND METHODS: A retrospective chart review of patients treated for kidney and/or ureteral stones between August 2014 and May 2016 was performed...
December 8, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27930405/the-cost-of-crohn-s-disease-varied-health-care-expenditure-patterns-across-distinct-disease-trajectories
#20
Bhavana B Rao, Benjamin H Click, Ioannis E Koutroubakis, Claudia Ramos Rivers, Miguel Regueiro, Jason Swoger, Marc Schwartz, Jana Hashash, Arthur Barrie, Michael A Dunn, David G Binion
BACKGROUND: Patients with Crohn's disease (CD) encompass a heterogeneous disease spectrum, with variable health care utilization and expenditure patterns. Lémann Index (LI) is a metric that quantifies cumulative bowel damage and has shown utility in delineating distinct disease phenotypes. We aimed to characterize the financial burden from all medical care in CD cohort in relation to the variations in LI-based disease phenotypes. METHODS: CD patients with 5-year (y) follow-up from a prospective registry were included...
December 7, 2016: Inflammatory Bowel Diseases
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