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https://www.readbyqxmd.com/read/29688088/constant-light-during-lactation-programs-circadian-and-metabolic-systems
#1
Palma-Gómez Madahi, Osnaya Ivan, Balderas Adriana, Ortega Diana, Escobar Carolina
Exposure to light at night is a disruptive condition for the adult circadian system, leading to arrhythmicity in nocturnal rodents. Circadian disruption is a risk factor for developing physiological and behavioral alterations, including weight gain and metabolic disease. During early stages of development, the circadian system undergoes a critical period of adjustment, and it is especially vulnerable to altered lighting conditions that may program its function, leading to long-term effects. We hypothesized that during lactation a disrupted light-dark cycle due to light at night may disrupt the circadian system and in the long term induce metabolic disorders...
April 24, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29491873/low-light-dependence-of-the-magnetic-field-effect-on-cryptochromes-possible-relevance-to-plant-ecology
#2
Jacques Vanderstraeten, Philippe Gailly, E Pascal Malkemper
Various responses to static magnetic fields (MF) have been reported in plants, and it has been suggested that the geomagnetic field influences plant physiology. Accordingly, diverse mechanisms have been proposed to mediate MF effects in plants. The currently most probable sensor candidates are cryptochromes (Cry) which are sensitive to submillitesla MF. Here, we propose a quantitative approach of the MF effect on Cry depending on light intensity, and try to link it to a possible functional role for magnetic sensitivity in plants...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29489022/ignoring-children-s-bedtime-crying-the-power-of-western-oriented-beliefs
#3
Monique Maute, Sonja Perren
Ignoring children's bedtime crying (ICBC) is an issue that polarizes parents as well as pediatricians. While most studies have focused on the effectiveness of sleep interventions, no study has yet questioned which parents use ICBC. Parents often find children's sleep difficulties to be very challenging, but factors such as the influence of Western approaches to infant care, stress, and sensitivity have not been analyzed in terms of ICBC. A sample of 586 parents completed a questionnaire to investigate the relationships between parental factors and the method of ICBC...
March 2018: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28816621/use-disuse-paradigms-are-ubiquitous-concepts-in-characterizing-the-process-of-inheritance
#4
Sophie Juliane Veigl
In recent years, a Lamarckian theme has found its way back into academic discourse on evolution and inheritance. Especially the emerging field of transgenerational small RNAs has provided at least a proof of concept for the inheritance of acquired traits. Yet it remains unclear whether the Lamarckian concept of inheritance will in fact have its rennaisance or whether it will remain the rallying cry for the outlaws, heretics and enfants terribles of molecular biology. As unclear as the future of Lamarckian theory is its content and reference...
December 2, 2017: RNA Biology
https://www.readbyqxmd.com/read/28751800/light-and-temperature-signalling-at-the-level-of-cbf14-gene-expression-in-wheat-and-barley
#5
Aliz Novák, Ákos Boldizsár, Krisztián Gierczik, Attila Vágújfalvi, Éva Ádám, László Kozma-Bognár, Gábor Galiba
The wheat and barley CBF14 genes have been newly defined as key components of the light quality-dependent regulation of the freezing tolerance by the integration of phytochrome-mediated light and temperature signals. To further investigate the wavelength dependence of light-induced CBF14 expression in cereals, we carried out a detailed study using monochromatic light treatments at an inductive and a non-inductive temperature. Transcript levels of CBF14 gene in winter wheat Cheyenne, winter einkorn G3116 and winter barley Nure genotypes were monitored...
2017: Plant Molecular Biology Reporter
https://www.readbyqxmd.com/read/28707325/effects-of-scalp-nerve-block-on-pain-and-emergence-agitation-after-paediatric-nevus-surgery-a-clinical-trial
#6
J-S Kim, G W Kim, D H Park, H E Ahn, M Y Chang, J Y Kim
BACKGROUND: Pain is considered as being one cause of post-operative emergence agitation (EA) from sevoflurane anaesthesia. The purpose of this study was to investigate the pure effect of post-operative pain on EA after sevoflurane anaesthesia in preschool children undergoing excision of scalp nevi. METHODS: Forty-four children, 1-7 years old, undergoing scalp nevus excision were enrolled. Patients were randomly assigned to two groups: the remifentanil group received single intravenous injection of short-acting synthetic opioid, remifentanil 1 μg/kg just before the scalp incision, and the block group received scalp nerve block with 0...
September 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28448335/cry-it-out-what-is-it-and-is-it-appropriate
#7
Judy A Beal
No abstract text is available yet for this article.
May 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28316108/cry1a-b-16-toxin-from-bacillus-thuringiensis-theoretical-refinement-of-three-dimensional-structure-and-prediction-of-peptides-as-molecular-markers-for-detection-of-genetically-modified-organisms
#8
Alexandra Plácido, Andreia Coelho, Lucas Abreu Nascimento, Andreanne Gomes Vasconcelos, Maria Fátima Barroso, Joilson Ramos-Jesus, Vladimir Costa, Francisco das Chagas Alves Lima, Cristina Delerue-Matos, Ricardo Martins Ramos, Mariela M Marani, José Roberto de Souza de Almeida Leite
Transgenic maize produced by the insertion of the Cry transgene into its genome became the second most cultivated crop worldwide. Cry gene from Bacillus thuringiensis kurstaki expresses protein derivatives of crystalline endotoxins which confer insect resistance onto the maize crop. Mandatory labeling of processed food containing or made by genetically modified organisms is in force in many countries, so, it is very urgent to develop fast and practical methods for GMO identification, for example, biosensors...
July 2017: Proteins
https://www.readbyqxmd.com/read/28141730/-footprints-in-the-bathroom-the-role-of-spirituality-in-patient-diagnosis
#9
Veronica Meneses, Douglas Vanderbilt, Linda Barnes, Marilyn Augustyn
Lucy is a 12-year-old Latina whose mother brought her to the pediatric clinic for help with her anxiety symptoms, "hearing voices," and episodes of "spacing out." Lucy did not cry at birth secondary to vocal cord paralysis and still has the tracheostomy performed at a few days of life. In addition to her neonatal intensive care unit stay, she has been hospitalized for pneumonia. Her mother says she is "sickly" and has a weak immune system due to her asthma symptoms. Lucy also experiences somatic complaints related to gastroesophageal reflux and constipation...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/27894389/-qualitative-study-on-the-current-status-of-hospitalized-burn-children-s-quality-of-life
#10
R Q Lin, L Li, L Xu, Q Pan, J X Dai
Objective: To explore the current status of hospitalized burn children's quality of life, so as to lay foundation for carrying out the related intervention in future. Methods: Using qualitative research method, semi-structured interviews were conducted on 11 parents of burn children hospitalized in Department of Burns of Fujian Medical University Union Hospital from March to May 2016. Then the data were analyzed and concluded with phenomenological analysis method to refine the themes. Results: Parents' description about the current status of hospitalized burn children's quality of life could be summed up into four areas: physiology, psychology, social development, and family; and in six themes: obvious itching symptom, limited movement development, night terror and constant cry because of fear, reduced social game, negative attachment type, and parents under multiple pressures...
November 20, 2016: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/27617345/highly-selective-and-sensitive-electrochemical-immunoassay-of-cry1c-using-nanobody-and-%C3%AF-%C3%AF-stacked-graphene-oxide-thionine-assembly
#11
Qing Zhou, Guanghui Li, Yuanjian Zhang, Min Zhu, Yakun Wan, Yanfei Shen
Cry1C is one of the emerging toxin proteins produced by the Bacillus thuringiensis in the genetically modified crops for pest control in agriculture; thus, it is vital to measure the Cry1C level in crops for the healthy and environmental concerns. Current detections of Cry1C mainly rely on instrumental analysis such as high-performance liquid chromatography, which are time-consuming and are generally cost-prohibitive. Herein, a simple nanobodies (Nbs)-based electrochemical immunosensor has been first proposed for highly selective and sensitive detection of Cry1C...
October 4, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27609027/descriptive-figures-for-differences-in-parenting-and-infant-night-time-distress-in-the-first-three-months-of-age
#12
COMPARATIVE STUDY
Ian St James-Roberts, Marion Roberts, Kimberly Hovish, Charlie Owen
Aim To provide descriptive figures for infant distress and associated parenting at night in normal London home environments during the first three months of age. BACKGROUND: Most western infants develop long night-time sleep periods by four months of age. However, 30% of infants in many countries sleep for short periods and cry out on waking in the night: the most common type of infant sleep behaviour problem. Preventive interventions may help families and improve services. There is evidence that 'limit-setting' parenting, which is common in western cultures, supports the development of settled infant night-time behaviour...
November 2016: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/26559210/-fifty-years-of-public-service-for-quebec-community-psychiatry-services-part-i
#13
Alain Lesage
This essay comprises 2 parts. It aims to recognize the public service of psychiatrists of the Département de psychiatrie de l'Université de Montréal who served at the provincial level of the Ministry of Health and Social Services for deinstitutionalisation of policies and organisation of services, at the service of people with severe mental disorders. First with Dr. Camille Laurin post-face of the 1962 book Les fous crient au secours! (Mentally ill patients cry for help); then the insight on the latest phase of differentiated specialised clinics by Dr...
2015: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/26513483/food-safety-knowledge-on-the-bt-mutant-protein-cry8ka5-employed-in-the-development-of-coleopteran-resistant-transgenic-cotton-plants
#14
REVIEW
Davi F Farias, Ad A C M Peijnenburg, Maria F Grossi-de-Sá, Ana F U Carvalho
Insecticidal Cry proteins from Bacillus thuringiensis (Bt) have been exploited in the development of genetically modified (GM) crops for pest control. However, several pests are still difficult to control such as the coleopteran boll weevil Anthonomus grandis. By applying in vitro molecular evolution to the cry8Ka1 gene sequence, variants were generated with improved activity against A. grandis. Among them, Cry8Ka5 mutant protein showed coleoptericidal activity 3-fold higher (LC50 2.83 μg/mL) than that of the original protein (Cry8Ka1)...
2015: Bioengineered
https://www.readbyqxmd.com/read/26329943/attitude-and-practices-of-mothers-on-breastfeeding-attended-at-a-tertiary-hospital-in-bangladesh
#15
M Akhtaruzzaman, M A Hossain, M R Karim, R H Khan, M S Islam, F Ahamed, N Khan, S U Ahammed, S K Dhar, A A Mahmud, A K Khan, S Nahar
This descriptive cross sectional study was conducted in Pediatric Out Patient Department (OPD) of Mymensingh Medical College Hospital (MMCH) from November 2013 to April 2014 to assess the knowledge and practices of the mothers about breastfeeding. Four hundred mothers having children 6 months to 2 years of age attended at OPD of MMCH for any cause were included in the study by systematic random sampling. A structured, pre-tested, interview schedule was used to collect data from mothers. All mothers were continuing to breastfeed their children...
July 2015: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/25676645/breath-holding-spells-in-infants
#16
Ran D Goldman
QUESTION: I have children in my clinic who experience seizurelike episodes in which they cry and hold their breath to the point of cyanosis and loss of consciousness. Their examination or investigation findings are normal and referral to a pediatric specialist results in no further investigation. Are breath-holding spells common, and what type of investigation is needed? ANSWER: A breath-holding spell is a benign paroxysmal nonepileptic disorder occurring in healthy children 6 to 48 months of age...
February 2015: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/25662458/purification-and-analysis-of-period-protein-complexes-of-the-mammalian-circadian-clock
#17
Jin Young Kim, Pieter Bas Kwak, Michael Gebert, Hao A Duong, Charles J Weitz
In mammals, circadian rhythms are generated at least in part by a cell-autonomous transcriptional feedback loop in which the three PERIOD (PER) and two CRYPTOCHROME (CRY) proteins inhibit the activity of the dimeric transcription factor CLOCK-BMAL1, thereby repressing their own expression. Upon nuclear entry, the PER and CRY proteins form a large protein complex (PER complex) that carries out circadian negative feedback by means of at least two basic functions: (1) it brings together multiple effector proteins that repress transcription and (2) it delivers these repressive effectors directly to CLOCK-BMAL1 bound to E-box sequences of circadian target genes...
2015: Methods in Enzymology
https://www.readbyqxmd.com/read/25317506/serendipitous-discovery-of-short-peptides-from-natural-products-as-tyrosinase-inhibitors
#18
Nai-Wan Hsiao, Tien-Sheng Tseng, Yu-Ching Lee, Wang-Chuan Chen, Hui-Hsiung Lin, Yun-Ru Chen, Yeng-Tseng Wang, Hung-Ju Hsu, Keng-Chang Tsai
Tyrosinase, which is the crucial copper-containing enzyme involved in melanin synthesis, is strongly associated with hyperpigmentation disorders, cancer, and neurodegenerative disease; thus, it has attracted considerable interest in the fields of medicine and cosmetics. The known tyrosinase inhibitors show numerous adverse side effects, and there is a lack of safety regulations governing their use. As a result, there is a need to develop novel inhibitors with no toxicity and long-term stability. In this study, we use molecular docking and pharmacophore modeling to construct a reasonable and reliable pharmacophore model, called Hypo 1, that could be used for identifying potent natural products with crucial complementary functional groups for mushroom tyrosinase inhibition...
November 24, 2014: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/25254162/pediatric-palliative-care-the-role-of-the-patient-s-family
#19
REVIEW
Carl Friedrich Classen
Whenever a child suffers, what does she or he cry Mother! What does that mean Palliative care is not a type of medicine based on objective evidence or statistics. The only relevant standard is the very individual quality of life. Nobody knows better what this actually means but the patient himself. Thus, if the mother's presence has the biggest impact on a child's wellbeing or comfort, she herself is the most valuable treatment modality. In nearly every publication dealing with pediatric palliative care, it is stated that palliative care does not only imply care for the sick child but also for the parents and the whole family...
October 8, 2012: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/25225507/coping-strategies-for-stress-used-by-adolescent-girls-in-riyadh-kingdom-of-saudi-arabia
#20
Hafsa Raheel
OBJECTIVES: Secondary school girls, ages 15 - 19 yrs were surveyed to find out the coping strategies they used when stressed. Adolescents, who are affected with stress and depression early in life, suffer from depression throughout their lives especially if they are utilizing improper ways to cope with it. METHODS: A cross sectional school based survey among 1028 adolescent girls was conducted among the secondary schools in Riyadh city,Kingdom of Saudi Arabia. RESULTS: About 25% stated that they cry, 19% listen to music, 15% start eating a lot, 12% sit alone/isolate themselves, 11% pray/read the Quran, 10% get into a verbal argument or a fight...
September 2014: Pakistan Journal of Medical Sciences Quarterly
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