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Coronary computed tomography angiography

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https://www.readbyqxmd.com/read/28624404/accuracy-of-j-cto-score-derived-from%C3%A2-computed-tomography-versus-angiography-to-predict-successful-percutaneous-coronary-intervention
#1
Akiko Fujino, Satoru Otsuji, Katsuyuki Hasegawa, Toyohiro Arita, Shin Takiuchi, Kenichi Fujii, Masanori Yabuki, Motoaki Ibuki, Shinya Nagayama, Kasumi Ishibuchi, Toshikazu Kashiyama, Rui Ishii, Hiroto Tamaru, Wataru Yamamoto, Masahiko Hara, Yorihiko Higashino
OBJECTIVES: The aim of this study was to compare the ability of conventional versus computed tomography angiography (CTA) to predict procedural success and 30-min wire crossing rates in percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions. BACKGROUND: Coronary CTA can be used to assess the morphology of CTO lesions. METHODS: We examined 205 consecutive patients (218 CTO lesions) who underwent coronary CTA pre-PCI...
June 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28624401/the-external-validity-of-prediction-models-for-the-diagnosis-of-obstructive-coronary-artery-disease-in-patients-with-stable-chest-pain-insights-from-the-promise-trial
#2
Tessa S S Genders, Adrian Coles, Udo Hoffmann, Manesh R Patel, Daniel B Mark, Kerry L Lee, Ewout W Steyerberg, M G Myriam Hunink, Pamela S Douglas
OBJECTIVES: This study sought to externally validate prediction models for the presence of obstructive coronary artery disease (CAD). BACKGROUND: A better assessment of the probability of CAD may improve the identification of patients who benefit from noninvasive testing. METHODS: Stable chest pain patients from the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) trial with computed tomography angiography (CTA) or invasive coronary angiography (ICA) were included...
June 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28622946/estimation-of-myocardial-flow-reserve-utilizing-an-ultrafast-cardiac-spect-comparison-with-coronary-angiography-fractional-flow-reserve-and-the-syntax-score
#3
Masao Miyagawa, Yoshiko Nishiyama, Teruyoshi Uetani, Akiyoshi Ogimoto, Shuntaro Ikeda, Hayato Ishimura, Emiri Watanabe, Rami Tashiro, Yuki Tanabe, Teruhito Kido, Akira Kurata, Teruhito Mochizuki
BACKGROUND: Quantitative assessment of myocardial flow reserve (MFR) by single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is challenging but may facilitate evaluation of multi-vessel coronary artery disease (CAD). METHODS: We enrolled 153 patients with suspected or known CAD, referred for pharmacological stress MPI. They underwent a (99m)Tc-perfusion stress/rest SPECT with an ultrafast cadmium-zinc-telluride (CZT) camera. Dynamic data were acquired and time-activity curves fitted to a 1-tissue compartment analysis with input function...
June 13, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28621042/clinical-evaluation-of-anomalous-aortic-origin-of-a-coronary-artery-aaoca
#4
Silvana Molossi, Hitesh Agrawal
The clinical evaluation of patients with an anomalous aortic origin of a coronary artery (AAOCA), a congenital abnormality of the origin or course of a coronary artery that arises from the aorta, is challenging given its first presentation being sudden cardiac arrest in about half of the patients. Symptoms of chest pain, shortness of breath and syncope during exertion should be of concern in evaluating young athletes and nonathletes. The lack of abnormal signs on the physical exam and electrocardiogram further adds to the difficulty in establishing the diagnosis...
June 16, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28616562/coronary-calcification-compromises-myocardial-perfusion-irrespective-of-luminal-stenosis
#5
Michael Y Henein, Tarek Bengrid, Rachel Nicoll, Ying Zhao, Bengt Johansson, Axel Schmermund
AIM: The aim of this study was to evaluate the relationship between coronary artery calcification (CAC) assessed by multi-detector computed tomography (MDCT) and myocardial perfusion assessed by cardiac magnetic resonance imaging (CMR) in a group of symptomatic patients. METHOD: Retrospective analysis of 120 patients (age 65.1 ± 8.9 years, 88 males) who presented with atypical chest pain to Bethanien Hospital, Frankfurt, Germany, between 2007 and 2010 and who underwent CAC scoring using MDCT, CMR, and conventional coronary angiography...
March 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28616535/effect-of-intravenous-infusion-of-iodinated-contrast-media-on-the-coronary-blood-flow-in-dogs
#6
Thura T Abd, Asim I Shafique, Hayder S Yasir, Jung-Hee Seo, Richard T George, Rajat Mittal, Albert C Lardo
BACKGROUND: Coronary computed tomography angiography (CCTA) is obtained using peripheral intravenous iodinated contrast agents (ICA) injection. There is continuing attempts to derive coronary physiological information like coronary blood flow (CBF) and/or fractional flow reserve from CCTA images. However, no data is available regarding the effect of peripheral intravenous injection of ICA on CBF. METHODS: A series of 4 experiments was performed using healthy mongrel dogs...
September 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28614421/zero-calcium-score-as-a-filter-for-further-testing-in-patients-admitted-to-the-coronary-care-unit-with-chest-pain
#7
Luis Cláudio Lemos Correia, Fábio P Esteves, Manuela Carvalhal, Thiago Menezes Barbosa de Souza, Nicole de Sá, Vitor Calixto de Almeida Correia, Felipe Kalil Beirão Alexandre, Fernanda Lopes, Felipe Ferreira, Márcia Noya-Rabelo
Background: The accuracy of zero coronary calcium score as a filter in patients with chest pain has been demonstrated at the emergency room and outpatient clinics, populations with low prevalence of coronary artery disease (CAD). Objective: To test the gatekeeping role of zero calcium score in patients with chest pain admitted to the coronary care unit (CCU), where the pretest probability of CAD is higher than that of other populations. Methods: Patients underwent computed tomography for calcium scoring, and obstructive CAD was defined by a minimum 70% stenosis on invasive angiography...
June 12, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28613933/quantification-of-radiation-dose-reduction-by-reducing-z-axis-coverage-in-320-detector-coronary-ct-angiography
#8
D J Murphy, A Keraliya, N Himes, A Aghayev, R Blankstein, M L Steigner
OBJECTIVES: To quantify the radiation dose reduction achievable by minimizing z-axis coverage in 320-detector coronary computed tomography angiography (CCTA). METHODS: We retrospectively reviewed 130 CCTAs performed on 320-detector CT that offers up to 16cm z-axis coverage (adjustable in 2cm increments), allowing complete coverage of the heart in a single gantry rotation. For each CT we obtained the radiation dose (CTDIvol and DLP), measured the z-axis field of view and measured the craniocaudal cardiac size (distance from the left main coronary artery to the cardiac apex)...
June 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28613405/an-association-between-volumes-of-the-cardiac-chambers-and-troponin-levels-in-individuals-submitted-to-cardiac-coronary-computed-tomography
#9
Zach Rozenbaum, Yaron Arbel, Yoav Granot, Dotan Cohen, Haim Shmilovich, Tomer Ziv-Baran, Ehud Chorin, Ofer Havakuk, Merav Cohen, Shlomo Berliner, Yan Topilsky, Galit Aviram
BACKGROUND: Previous echocardiographic studies have revealed an association between enlarged cardiac chamber volumes and elevated troponin concentrations. An automatic 4-chamber volumetric analysis tool was adopted to investigate this association in patients who underwent cardiac-gated computed tomography angiography (CCTA). HYPOTHESIS: We hypothesized that troponin concentration within the normal range correlates with cardiac chambers' volumes. METHODS: Serum troponin was obtained from 157 ambulatory patients before undergoing CCTA for nonacute coronary artery evaluation...
June 14, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28611006/intensive-versus-moderate-atorvastatin-therapy-and-one-year-graft-patency-after-cabg-rationale-and-design-of-the-active-aggressive-cholesterol-therapy-to-inhibit-vein-graft-events-randomized-controlled-trial-nct01528709
#10
Alexander Kulik, Amy M Abreu, Viviana Boronat, Marc Ruel
RATIONALE: Saphenous vein graft disease remains a major limitation of coronary artery bypass graft surgery (CABG). Statin therapy inhibits the development of vein graft disease and improves outcomes after CABG. However, it is unclear whether treatment with high-dose statins will further slow the process of vein graft disease and improve graft patency, as compared to conventional moderate doses. Therefore, the goal of this study will be to evaluate the efficacy of high-dose statin therapy versus moderate-dose statin therapy for the prevention of saphenous vein graft occlusion following CABG...
June 10, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28608183/acc-aats-aha-ase-asnc-scai-scct-sts-2017-appropriate-use-criteria-for-coronary-revascularization-in-patients-with-stable-ischemic-heart-disease-a-report-of-the-american-college-of-cardiology-appropriate-use-criteria-task-force-american-association-for-thoracic
#11
Manesh R Patel, John H Calhoon, Gregory J Dehmer, James Aaron Grantham, Thomas M Maddox, David J Maron, Peter K Smith
The American College of Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, and American Association for Thoracic Surgery, along with key specialty and subspecialty societies, have completed a 2-part revision of the appropriate use criteria (AUC) for coronary revascularization. In prior coronary revascularization AUC documents, indications for revascularization in acute coronary syndromes and stable ischemic heart disease (SIHD) were combined into 1 document. To address the expanding clinical indications for coronary revascularization, and to align the subject matter with the most current American College of Cardiology/American Heart Association guidelines, the new AUC for coronary artery revascularization were separated into 2 documents addressing SIHD and acute coronary syndromes individually...
June 12, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28607546/histologic-sequelae-of-apical-hypertrophic-cardiomyopathy-dystrophic-calcification
#12
Shahryar G Saba, John N Makaryus, Navid Rahmani, Ram Jadonath
We present cardiac computed tomography (CT) findings demonstrating apical hypertrophic cardiomyopathy with dystrophic calcification of the left ventricular apex. The absence of significant epicardial coronary artery disease demonstrated by coronary CT angiography suggests that increased wall tension and decreased microvascular perfusion over time account for the dyskinetic apical myocardium, rather than myocardial infarction secondary to atherosclerotic plaque rupture. These observations support CT as the imaging modality of choice to visualize the deposition of calcium in injured myocardial tissue, a recognized occurrence in chronically infarcted myocardium...
2017: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/28600860/estimating-the-accuracy-of-a-reduced-order-model-for-the-calculation-of-fractional-flow-reserve-ffr
#13
Etienne Boileau, Sanjay Pant, Carl Roobottom, Igor Sazonov, Jingjing Deng, Xianghua Xie, Perumal Nithiarasu
Image-based non-invasive fractional flow reserve (FFR) is an emergent approach to determine the functional relevance of coronary stenoses. The present work aimed to determine the feasibility of using a method based on coronary computed tomography angiography (CCTA) and reduced-order models (0D-1D) for the evaluation of coronary stenoses. The reduced-order methodology (cFFRro ) was kept as simple as possible and did not include pressure drop or stenosis models. The geometry definition was incorporated into the physical model used to solve coronary flow and pressure...
June 9, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28600674/-value-of-cardiac-ct-in-the-diagnostic-work-up-of-coronary-artery-disease-update-2017
#14
M Meyer, T Henzler
The quantification of coronary calcifications using noncontrast-enhanced computed tomography (CT) as well as coronary CT angiography (cCTA) have rapidly evolved in the recent years. Nowadays, both techniques are increasingly clinically accepted regarding risk stratification and accurate exclusion of significant coronary artery disease (CAD). The higher acceptance of cCTA is mainly based on the higher robustness, lower radiation exposure through continuous technical innovations as well as by the growing scientific evidence...
June 9, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28597744/noninvasive-techniques-for-the-diagnosis-of-anomalous-origin-of-the-left-coronary-artery-from-the-pulmonary-artery-in-adult-patients
#15
Natalia DłużNiewska, Magdalena Kostkiewicz, Lidia Tomkiewicz-Pająk, Maciej Krupiński, Jakub Podolec, Maria Olszowska, Piotr Podolec
Background Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital cardiac anomaly which requires surgical treatment, which improves left ventricular function and clinical outcomes. The definitive diagnosis of ALCAPA is based on coronary angiography, however, noninvasive visualization of the origin of the coronary artery is often helpful in the diagnosis of ALCAPA. Objectives The purpose of this study was to evaluate noninvasive techniques for the diagnosis of ALCAPA, and present the clinical outcomes in adults after surgical correction of ALCAPA...
February 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28597738/improved-diagnostic-accuracy-when-combining-computed-tomography-angiography-and-corrected-coronary-opacification-in-patients-with-coronary-stents
#16
Taylor F Dowsley, Leonid Chepelev, Brian McArdle, Mohammed Alam, Girish Dwivedi, Benjamin J W Chow
Background The accuracy of coronary computed tomography angiography (CCTA) is sub-optimal in patients with coronary stents. Methods that can increase its diagnostic accuracy are desirable. Objective A proof-of-concept study was undertaken to determine if corrected coronary opacification (CCO) differences can improve the accuracy of CCTA in stented coronary arteries. Methods PCI patients who underwent both CCTA and invasive coronary angiography (ICA) within 3 months were analyzed. Coronary luminal attenuation values (normalized to the aorta) were measured proximally and distally to coronary stents...
February 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28595860/diagnostic-performance-of-a-novel-method-for-fractional-flow-reserve-computed-from-noninvasive-computed-tomography-angiography-novel-flow-study
#17
Ju-Hyun Chung, Kyung Eun Lee, Chang-Wook Nam, Joon-Hyung Doh, Hyung Il Kim, Soon-Sung Kwon, Eun Bo Shim, Eun-Seok Shin
Coronary computed tomography angiography (CCTA)-derived fractional flow reserve from computed tomography (CT-FFR) may provide better diagnostic performance over CCTA alone, but the complexity of its method limits the use in clinical environment. The aim of the present study is to validate a newly developed vessel-length based computational fluid dynamics scheme for the computation of FFR based on CCTA data, compare them with invasively measured FFR, and evaluate its diagnostic performance with that of CCTA...
May 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28595696/left-main-coronary-artery-compression-in-patients-with-pulmonary-arterial-hypertension-and%C3%A2-angina
#18
Nazzareno Galiè, Francesco Saia, Massimiliano Palazzini, Alessandra Manes, Vincenzo Russo, Maria Letizia Bacchi Reggiani, Gianni Dall'Ara, Enrico Monti, Fabio Dardi, Alessandra Albini, Andrea Rinaldi, Enrico Gotti, Nevio Taglieri, Cinzia Marrozzini, Luigi Lovato, Maurizio Zompatori, Antonio Marzocchi
BACKGROUND: Left main coronary artery (LMCA) compression is increasingly recognized as a cause of angina in pulmonary arterial hypertension (PAH). OBJECTIVES: This study aimed to evaluate the prevalence of LMCA extrinsic compression from a dilated pulmonary artery (PA) in patients with PAH and angina or angina-like symptoms, determine the usefulness of screening with computed tomography coronary angiography (CTCA), and assess the safety and efficacy of percutaneous coronary interventions (PCIs)...
June 13, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28592383/long-term-outcome-prediction-by-functional-parameters-derived-from-coronary-computed-tomography-angiography
#19
Dominik C Benz, Fran Mikulicic, Christoph Gräni, Dominic Moret, Mathias Possner, Olivier F Clerc, Annina A Studer Bruengger, Oliver Gaemperli, Ronny R Buechel, Aju P Pazhenkottil, Philipp A Kaufmann
BACKGROUND: Estimation of hemodynamic relevance of a coronary stenosis from coronary computed angiography (CCTA) has raised substantial interest. Recently, the corrected coronary opacification (CCO) decrease and the transluminal attenuation gradient (TAG) have been suggested as faster alternatives to the FFRCT. The aim of the study was to evaluate whether the diagnostic accuracy of CCO decrease and TAG translates into an added prognostic value in patients evaluated for coronary artery disease (CAD)...
May 24, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28591059/left-sinus-of-valsalva-aneurysm-ruptured-into-left-ventricle-a-case-report-of-320-multidetector-ct-findings
#20
Kyungsoo Bae, Kyung Nyeo Jeon, Hyang-Im Lee, Jeong Yoon Jang, Sung Eun Park, Kyeong Hwa Ryu, Hye Jin Baek, Bo Hwa Choi, Jin Il Moon, Soo Buem Cho
RATIONALE: Ruptured aneurysm originating from the left coronary sinus of Valsalva into the left ventricle (LV) is extremely rare. Imaging features of sinus aneurysm has been commonly reported using echocardiography or angiography. Here, we report multidetector computed tomography (MDCT) findings of left sinus of Valsalva aneurysm extending into the LV and caused severe aortic regurgitation (AR) in a 44-year-old male with latent infective endocarditis. The role of MDCT in preoperative surgical planning was also emphasized...
June 2017: Medicine (Baltimore)
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