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https://www.readbyqxmd.com/read/28115672/rickettsia-felis-infection-in-febrile-children-ghana
#1
Peter Sothmann, Christian Keller, Ralf Krumkamp, Benno Kreuels, Cassandra Aldrich, Nimako Sarpong, Stefanie Steierberg, Doris Winter, Kennedy Gyau Boahen, Ellis Owusu-Dabo, Jürgen May, Daniel Eibach
Rickettsial infections are an underrecognized cause of febrile illness in sub-Saharan Africa. To evaluate the epidemiology and clinical features of rickettsial disease in pediatric patients in Ghana, we screened blood samples from febrile children aged less than 15 years presenting to an outpatient department in Ghana's Ashanti Region for the presence of rickettsial DNA. We detected Rickettsia felis in 7/470 (1.5%) blood samples, using two independent real-time polymerase chain reactions. No other Rickettsia species were found...
January 23, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28107412/nasal-carriage-of-staphylococcus-aureus-among-children-in-the-ashanti-region-of-ghana
#2
Daniel Eibach, Michael Nagel, Benedikt Hogan, Clinton Azuure, Ralf Krumkamp, Denise Dekker, Mike Gajdiss, Melanie Brunke, Nimako Sarpong, Ellis Owusu-Dabo, Jürgen May
BACKGROUND: Nasal carriage with Staphylococcus aureus is a common risk factor for invasive infections, indicating the necessity to monitor prevalent strains, particularly in the vulnerable paediatric population. This surveillance study aims to identify carriage rates, subtypes, antimicrobial susceptibilities and virulence markers of nasal S. aureus isolates collected from children living in the Ashanti region of Ghana. METHODS: Nasal swabs were obtained from children < 15 years of age on admission to the Agogo Presbyterian Hospital between April 2014 and January 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28104671/lack-of-association-of-cd55-receptor-genetic-variants-and-severe-malaria-in-ghanaian-children
#3
Kathrin Schuldt, Christa Ehmen, Juergen Sievertsen, Jennifer Evans, Juergen May, Daniel Ansong, Birgit Muntau, Gerd Ruge, Christian Timmann, Tsiri Agbenyega, Rolf D Horstmann, Thorsten Thye
In a recent report the cellular receptor CD55 was identified as a molecule essential for the invasion of human erythrocytes by Plasmodium falciparum, the causal agent of the most severe form of malaria. As this invasion process represents a critical step during the infection with the parasite, it was hypothesized that genetic variants in the gene could affect severe malaria susceptibility. We performed high-resolution variant discovery of rare and common genetic variants in the human CD55 gene. Association testing of these variants in over 1 700 severe malaria cases and unaffected control individuals from a malaria-endemic Ashanti Region in Ghana, West Africa, were performed on the basis of single variants, combined rare variant analyses, and reconstructed haplotypes...
January 18, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28088259/integration-for-coexistence-implementation-of-intercultural-health-care-policy-in-ghana-from-the-perspective-of-service-users-and-providers
#4
Razak Mohammed Gyasi, Adjoa Afriyie Poku, Simon Boateng, Padmore Adusei Amoah, Alhassan Abdul Mumin, Jacob Obodai, Williams Agyemang-Duah
OBJECTIVE: In spite of the World Health Organization's recommendations over the past decades, Ghana features pluralistic rather than truly integrated medical system. Policies about the integration of complementary medicine into the national health care delivery system need to account for individual-level involvement and cultural acceptability of care rendered by health care providers. Studies in Ghana, however, have glossed over the standpoint of the persons of the illness episode about the intercultural health care policy framework...
January 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28061905/epidemiology-of-mansonella-perstans-in-the-middle-belt-of-ghana
#5
Linda Batsa Debrah, Norman Nausch, Vera Serwaa Opoku, Wellington Owusu, Yusif Mubarik, Daniel Antwi Berko, Samuel Wanji, Laura E Layland, Achim Hoerauf, Marc Jacobsen, Alexander Yaw Debrah, Richard O Phillips
BACKGROUND: Mansonellosis was first reported in Ghana by Awadzi in the 1990s. Co-infections of Mansonella perstans have also been reported in a small cohort of patients with Buruli ulcer and their contacts. However, no study has assessed the exact prevalence of the disease in a larger study population. This study therefore aimed to find out the prevalence of M. perstans infection in some districts in Ghana and to determine the diversity of Culicoides that could be potential vectors for transmission...
January 7, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/27973260/household-cost-of-injuries-in-children-under-five-years-in-the-ejisu-juabeng-municipality-of-the-ashanti-region-ghana-a-cross-sectional-study
#6
J Amissah
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27938360/overweight-and-obesity-epidemic-in-ghana-a-systematic-review-and-meta-analysis
#7
Richard Ofori-Asenso, Akosua Adom Agyeman, Amos Laar, Daniel Boateng
BACKGROUND: In many low and middle income countries (LMICs), the distribution of adulthood nutritional imbalance is shifting from a predominance of undernutrition to overnutrition. This complex problem poses a huge challenge to governments, non-state actors, and individuals desirous of addressing the problem of malnutrition in LMICs. The objective of this study was to systematically review the literature towards providing an estimate of the prevalence of overweight and obesity among adult Ghanaians...
December 9, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27927238/insecticide-resistance-in-malaria-vectors-in-kumasi-ghana
#8
Sandra Baffour-Awuah, Augustina A Annan, Oumou Maiga-Ascofare, Soma Diloma Dieudonné, Priscilla Adjei-Kusi, Ellis Owusu-Dabo, Kwasi Obiri-Danso
BACKGROUND: There have been recent reports of surge in resistance to insecticides in pocketed areas in Ghana necessitating the need for information about local vector populations and their resistance to the insecticides approved by the World Health Organization (WHO). We therefore studied a population of malaria vectors from Kumasi in the Ashanti Region of Ghana and their resistance to currently used insecticides. We conducted susceptibility tests to the four major classes of insecticides by collecting larvae of anopheline mosquitoes from several communities in the region...
December 7, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27899074/antibiotic-resistance-and-clonal-diversity-of-invasive-staphylococcus-aureus-in-the-rural-ashanti-region-ghana
#9
Denise Dekker, Manuel Wolters, Eva Mertens, Kennedy Gyau Boahen, Ralf Krumkamp, Daniel Eibach, Norbert G Schwarz, Yaw Adu-Sarkodie, Holger Rohde, Martin Christner, Florian Marks, Nimako Sarpong, Jürgen May
BACKGROUND: Staphylococcus aureus is among the most common pathogens isolated from blood cultures in Ghana; yet the epidemiology of blood infections in rural settings is poorly described. This study aims to investigate antimicrobial susceptibility and clonal diversity of S. aureus causing bloodstream infections in two hospitals in the Ashanti Region, Ghana. METHODS: Blood cultures were performed for all febrile patients (≥37.5 °C) on hospital admission. Antibiotic susceptibility testing for S...
November 29, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27807453/comparative-analysis-of-households-solid-waste-management-in-rural-and-urban-ghana
#10
Simon Boateng, Prince Amoako, Divine Odame Appiah, Adjoa Afriyie Poku, Emmanuel Kofi Garsonu
The comparative analysis of solid waste management between rural and urban Ghana is largely lacking. This study investigated the solid waste situation and the organisation of solid waste management in both urban and rural settings from the perspective of households. The study employed cross-sectional survey covering both rural and urban districts in the Ashanti and Greater Accra Regions of Ghana. The study systematically sampled houses from which 400 households and respondents were randomly selected. Pearson's Chi square test was used to compare demographic and socioeconomic variables in rural and urban areas...
2016: Journal of Environmental and Public Health
https://www.readbyqxmd.com/read/27784594/scorecards-and-social-accountability-for-improved-maternal-and-newborn-health-services-a-pilot-in-the-ashanti-and-volta-regions-of-ghana
#11
Carolyn Blake, Nii Ankonu Annorbah-Sarpei, Claire Bailey, Yakubu Ismaila, Sylvia Deganus, Samuel Bosomprah, Francesco Galli, Sarah Clark
BACKGROUND: With the limited availability of quality emergency obstetric and newborn care (EmONC) in Ghana, and a lack of dialogue on the issue at district level, the Evidence for Action (E4A) program (2011-2015) initiated a pilot intervention using a social accountability approach in two regions of Ghana. OBJECTIVE: Using scorecards to assess and improve maternal and newborn health services, the intervention study evaluated the effectiveness of engaging multiple, health and non-health sector stakeholders at district level to improve the enabling environment for quality EmONC...
December 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/27641949/socio-demographic-factors-associated-with-dietary-behaviour-among-young-ghanaians-aged-15-34-years
#12
Acheampong Yaw Amoateng, Phidelia Theresa Doegah, Christopher Udomboso
This study used data from the 2008 Ghana Demographic and Health Survey to investigate the association between selected socio-demographic factors and dietary behaviour as measured by fruit and vegetable consumption among a sample of 6139 young people aged 15-34 years in Ghana. Overall, fruit and vegetable consumption was low in young people, but females were likely to consume more fruit and vegetables than their male counterparts. Respondents from the Mande ethnic group, those who resided in rural areas and those living in the Brong/Ahafo, Ashanti and the Eastern regions consumed more fruit and vegetables than those from other regions...
September 19, 2016: Journal of Biosocial Science
https://www.readbyqxmd.com/read/27599835/economic-burden-of-malaria-on-businesses-in-ghana-a-case-for-private-sector-investment-in-malaria-control
#13
Justice Nonvignon, Genevieve Cecilia Aryeetey, Keziah L Malm, Samuel Agyei Agyemang, Vivian N A Aubyn, Nana Yaw Peprah, Constance N Bart-Plange, Moses Aikins
BACKGROUND: Despite the significant gains made globally in reducing the burden of malaria, the disease remains a major public health challenge, especially in sub-Saharan Africa (SSA) including Ghana. There is a significant gap in financing malaria control globally. The private sector could become a significant source of financing malaria control. To get the private sector to appreciate the need to invest in malaria control, it is important to provide evidence of the economic burden of malaria on businesses...
2016: Malaria Journal
https://www.readbyqxmd.com/read/27598327/when-the-clinic-becomes-a-home-successful-vct-and-art-services-in-a-stressful-environment
#14
Jonathan Mensah Dapaah, Rachel Spronk
With the upscaling of antiretroviral therapy (ART) in resource-poor countries, many HIV-positive persons in Ghana have been accessing treatment in hospitals. Prevalence is relatively low compared to other African countries, 1.30%. HIV/AIDS remains heavily stigmatised in Ghana, which influences the provision and use of ART. This article investigates how HIV-positive persons accessing care and treatment go about their everyday lives in the ART clinic and how they have eventually come to see the clinic as a safe place that they call 'home'...
December 2016: SAHARA J: Journal of Social Aspects of HIV/AIDS Research Alliance
https://www.readbyqxmd.com/read/27570487/selection-of-reference-genes-for-expression-studies-of-xenobiotic-adaptation-in-tetranychus-urticae
#15
Mariany Ashanty Morales, Bianca Marie Mendoza, Laura Corley Lavine, Mark Daniel Lavine, Douglas Bruce Walsh, Fang Zhu
Quantitative real-time PCR (qRT-PCR) is an extensively used, high-throughput method to analyze transcriptional expression of genes of interest. An appropriate normalization strategy with reliable reference genes is required for calculating gene expression across diverse experimental conditions. In this study, we aim to identify the most stable reference genes for expression studies of xenobiotic adaptation in Tetranychus urticae, an extremely polyphagous herbivore causing significant yield reduction of agriculture...
2016: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/27527530/use-of-a-spatial-scan-statistic-to-identify-clusters-of-births-occurring-outside-ghanaian-health-facilities-for-targeted-intervention
#16
Samuel Bosomprah, Winfred Dotse-Gborgbortsi, Patrick Aboagye, Zoe Matthews
OBJECTIVE: To identify and evaluate clusters of births that occurred outside health facilities in Ghana for targeted intervention. METHODS: A retrospective study was conducted using a convenience sample of live births registered in Ghanaian health facilities from January 1 to December 31, 2014. Data were extracted from the district health information system. A spatial scan statistic was used to investigate clusters of home births through a discrete Poisson probability model...
November 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/27512708/malaria-rapid-diagnostic-test-evaluation-at-private-retail-pharmacies-in-kumasi-ghana
#17
Rauf Audu, Berko Panyin Anto, George Asumeng Koffuor, Akua Afriyie Abruquah, Kwame Ohene Buabeng
OBJECTIVE: Malaria rapid diagnostic test (MRDT) provides a good alternative to malaria microscopy diagnosis, particularly in resource-constrained settings. This study therefore evaluated MRDT in private retail pharmacies (PRPs) as a critical step in community case malaria management. METHODS: In a prospective, cross-over, validation survey at six PRPs in the Ashanti Region of Ghana, 1200 patients presenting with fever in the preceding 48 h were sampled. Fingerstick blood samples were collected for preparation of thick and thin blood films for malaria microscopy...
July 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27507267/epidemiology-of-hepatitis-c-virus-in-ghana-a-systematic-review-and-meta-analysis
#18
Akosua Adom Agyeman, Richard Ofori-Asenso, Andy Mprah, George Ashiagbor
BACKGROUND: To fully understand the burden of hepatitis C (HCV) infection in Ghana towards informing appropriate preventive measures, accurate prevalence estimates are needed. In this study, we estimate the prevalence of chronic HCV infection by systematically reviewing primary studies published between 1995 and 2015. METHODS: A systematic review and meta-analysis was conducted as per the PRISMA guidelines. Comprehensive searches for hepatitis C prevalence studies for the years 1995-2015 were conducted in PubMed, ScienceDirect, Google Scholar, Africa Journals Online (AJOL) and the WHO African Index Medicus databases...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27487853/ocular-complications-in-hiv-positive-patients-on-antiretroviral-therapy-in-ghana
#19
Alexander Martin-Odoom, Evelyn Yayra Bonney, Derek Kofi Opoku
BACKGROUND: Patients infected with human immunodeficiency virus (HIV) usually develop some form of ocular complication in the different segments of the eye due to immune deficiency. In Ghana, data regarding ocular complications among HIV/AIDS patients is scarce. This study investigated the occurrence of ocular complications in HIV infected patients undergoing antiretroviral therapy at the Agogo Presbyterian Hospital in the Ashanti Region of Ghana. METHODS: Blood samples were taken from 100 confirmed HIV infected patients...
August 3, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27473598/diagnostic-performance-of-the-luminex-xtag-gastrointestinal-pathogens-panel-to-detect-rotavirus-in-ghanaian-children-with-and-without-diarrhoea
#20
Amelie Leva, Daniel Eibach, Ralf Krumkamp, Julia Käsmaier, Dennis Rubbenstroth, Yaw Adu-Sarkodie, Jürgen May, Egbert Tannich, Marcus Panning
BACKGROUND: Rotavirus is one of the leading causes of childhood diarrhoea worldwide. The highest disease burden is seen in resource-constrained settings of sub-Saharan Africa. Recently, commercial multiplex PCR panels proved their accuracy to diagnose infectious gastroenteritis in Europe and the USA. However, data on their performance using samples from tropical regions in general and to detect rotavirus in particular remains scant. We aimed to analyse the diagnostic performance of the Luminex xTAG gastrointestinal pathogens panel, a multiplex PCR, to detect rotavirus in stool samples from Ghanaian children...
2016: Virology Journal
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