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https://www.readbyqxmd.com/read/27904615/the-effect-of-flaxseed-powder-on-insulin-resistance-indices-and-blood-pressure-in-prediabetic-individuals-a-randomized-controlled-clinical-trial
#1
Afrooz Javidi, Hassan Mozaffari-Khosravi, Azadeh Nadjarzadeh, Ali Dehghani, Mohammad Hassan Eftekhari
BACKGROUND: Designing the effective and early interventions can prevent progression of prediabetes to diabetes. Few studies have shown the effect of flaxseed on glycemic control. This study aimed to assess the effect of flaxseed powder on insulin resistance (IR) indices and blood pressure in prediabetic individuals. MATERIALS AND METHODS: In a randomized clinical trial, 99 prediabetic individuals were randomly divided into three groups: two groups received 40 g (FG40) and 20 g (FG20) flaxseed powder daily for 12 weeks and the third group was the control (CG)...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27897610/effect-of-calcitriol-supplementation-on-blood-pressure-in-older-adults
#2
Jaime Alberto Bricio-Barrios, Alín Jael Palacios-Fonseca, Mario Del Toro-Equihua, Carmen Alicia Sanchez-Ramirez
Recent studies suggest that vitamin D plays an important role in the control of blood pressure. Unfortunately, because older adults are more likely to have low 25-hydroxyvitamin-D [25(OH)D] levels, this study investigated whether calcitriol supplementation reduces blood pressure in older adults with hypertension. The design was a double-blind placebo-controlled randomized clinical trial with 36 randomly assigned subjects (71.7 ± 10 years). Blood pressure and serum levels of 25(OH)D before and after calcitriol intervention (1,000 IU daily for 6 weeks; n = 22) or placebo (n = 23) for 6 weeks were analyzed...
October 2016: Journal of Nutrition in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27893563/resistance-training-improves-muscle-function-and-cardiometabolic-risks-but-not-quality-of-life-in-older-people-with-type-2-diabetes-mellitus-a-randomized-controlled-trial
#3
Ping-Lun Hsieh, Chin-Hsiao Tseng, Yufeng Jane Tseng, Wei-Shiung Yang
BACKGROUND AND PURPOSE: In older people with type 2 diabetes mellitus (T2DM), the effects of aging and T2DM may compromise the function of skeletal muscle, deteriorate metabolic status, and jeopardize physical performance, aerobic capacity, and quality of life (QoL). The purpose of this study was to investigate the effects of 12 weeks of resistance training (RT) on muscle function, physical performance, cardiometabolic risks, and QoL in older people with T2DM. METHODS: This study was a randomized controlled trial that employed block randomization, assessor blinding, and the intention-to-treat principle...
November 23, 2016: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/27881568/incident-type-2-myocardial-infarction-in-a-cohort-of-patients-undergoing-coronary-or-peripheral-arterial-angiography
#4
Hanna K Gaggin, Yuyin Liu, Asya Lyass, Roland R van Kimmenade, Shweta R Motiwala, Noreen Kelly, Aditi Mallick, Parul U Gandhi, Nasrien E Ibrahim, Mandy Simon, Anju Bhardwaj, Arianna Belcher, Jamie E Harisiades, Joseph M Massaro, Ralph B D'Agostino, James L Januzzi
BACKGROUND: -Despite growing recognition of Type 2 myocardial infarction (T2MI; related to supply-demand mismatch), little is known about its risk factors or its association with outcome. METHODS: -A single center cohort of patients undergoing coronary or peripheral angiography with or without intervention was prospectively enrolled and followed for incident type 1 and T2MI, as well as major adverse cardiovascular events (MACE, a composite of all-cause death, non-fatal MI, heart failure, stroke, transient ischemic attack, peripheral arterial complication and cardiac arrhythmia)...
November 21, 2016: Circulation
https://www.readbyqxmd.com/read/27879359/effect-of-decide-decision-making-education-for-choices-in-diabetes-everyday-program-delivery-modalities-on-clinical-and-behavioral-outcomes-in-urban-african-americans-with-type-2-diabetes-a-randomized-trial
#5
Stephanie L Fitzpatrick, Sherita Hill Golden, Kerry Stewart, June Sutherland, Sharie DeGross, Tina Brown, Nae-Yuh Wang, Jerilyn Allen, Lisa A Cooper, Felicia Hill-Briggs
OBJECTIVE: To compare the effectiveness of three delivery modalities of Decision-making Education for Choices In Diabetes Everyday (DECIDE), a nine-module, literacy-adapted diabetes and cardiovascular disease (CVD) education and problem-solving training, compared with an enhanced usual care (UC), on clinical and behavioral outcomes among urban African Americans with type 2 diabetes. RESEARCH DESIGN AND METHODS: Eligible participants (n = 182) had a suboptimal CVD risk factor profile (A1C, blood pressure, and/or lipids)...
December 2016: Diabetes Care
https://www.readbyqxmd.com/read/27879180/-web-based-interventions-targeting-cardiovascular-risk-factors-in-older-people-a-systematic-review-and-meta-analysis
#6
C R L Beishuizen, W A van Gool, W B Busschers, R J G Peters, E P Moll van Charante, E Richard
OBJECTIVE: To evaluate whether web-based interventions for cardiovascular risk factor management reduce the risk of cardiovascular disease in older people. DESIGN: Systematic review and meta-analysis. METHOD: Embase, Medline, Cochrane Library and CINAHL were systematically searched from January 1995 to 3 November 2014. We included all randomised controlled trials for web-based interventions targeting cardiovascular risk factors in populations with a mean age of 50 and older...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27873322/non-medical-prescribing-versus-medical-prescribing-for-acute-and-chronic-disease-management-in-primary-and-secondary-care
#7
REVIEW
Greg Weeks, Johnson George, Katie Maclure, Derek Stewart
BACKGROUND: A range of health workforce strategies are needed to address health service demands in low-, middle- and high-income countries. Non-medical prescribing involves nurses, pharmacists, allied health professionals, and physician assistants substituting for doctors in a prescribing role, and this is one approach to improve access to medicines. OBJECTIVES: To assess clinical, patient-reported, and resource use outcomes of non-medical prescribing for managing acute and chronic health conditions in primary and secondary care settings compared with medical prescribing (usual care)...
November 22, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27872156/association-between-blood-pressure-and-adverse-renal-events-in-type-1-diabetes
#8
Elaine Ku, Charles E McCulloch, Michael Mauer, Stephen E Gitelman, Barbara A Grimes, Chi-Yuan Hsu
OBJECTIVE: To compare different blood pressure (BP) levels in their association with the risk of renal outcomes in type 1 diabetes and to determine whether an intensive glycemic control strategy modifies this association. RESEARCH DESIGN AND METHODS: We included 1,441 participants with type 1 diabetes between the ages of 13 and 39 years who had previously been randomized to receive intensive versus conventional glycemic control in the Diabetes Control and Complications Trial (DCCT)...
December 2016: Diabetes Care
https://www.readbyqxmd.com/read/27865822/ambulatory-blood-pressure-in-hypertensive-patients-with-inclusion-criteria-for-the-sprint-trial
#9
Alejandro de la Sierra, José R Banegas, Juan A Divisón, Manuel Gorostidi, Ernest Vinyoles, Juan J de la Cruz, Julián Segura, Luis M Ruilope
We aimed to characterize 24-hour blood pressure (BP) values and categories in patients with inclusion/exclusion criteria of the Systolic Blood Pressure Intervention (SPRINT) trial from the Spanish ABPM Registry. We selected patients older than 50 years, with office systolic BP (SBP) above 130 mm Hg and at high cardiovascular risk, but without diabetes, previous stroke, or symptomatic heart failure. Ambulatory BP was compared among BP categories. A total of 39,132 patients (34%) fulfilled inclusion criteria of SPRINT trial...
November 5, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27865620/consumption-of-chokeberry-aronia-mitschurinii-products-modestly-lowered-blood-pressure-and-reduced-low-grade-inflammation-in-patients-with-mildly-elevated-blood-pressure
#10
Britt-Marie Loo, Iris Erlund, Raika Koli, Pauli Puukka, Jarkko Hellström, Kristiina Wähälä, Pirjo Mattila, Antti Jula
Previous studies suggest that consumption of chokeberries may improve cardiovascular disease risk factor profiles. We hypothesized that chokeberries (Aronia mitschurinii) have beneficial effects on blood pressure, low-grade inflammation, serum lipids, serum glucose, and platelet aggregation in patients with untreated mild hypertension. A total of 38 participants were enrolled into a 16-week single blinded crossover trial. The participants were randomized to use cold-pressed 100% chokeberry juice (300 mL/d) and oven-dried chokeberry powder (3 g/d), or matched placebo products in random order for 8 weeks each with no washout period...
September 14, 2016: Nutrition Research
https://www.readbyqxmd.com/read/27863609/the-impact-of-listening-to-pleasant-natural-sounds-on-anxiety-and-physiologic-parameters-in-patients-undergoing-coronary-angiography-a-pragmatic-quasi-randomized-controlled-trial
#11
Nahid Rejeh, Majideh Heravi-Karimooi, Seyed Davood Tadrisi, Ali Jahani, Mojtaba Vaismoradi, Sue Jordan
OBJECTIVE: This study aimed to investigate the impact of listening to pleasant natural sounds on anxiety and physiological parameters in patients undergoing coronary angiography. METHODS: The present pragmatic quasi-randomized controlled clinical trial was conducted on 130 patients undergone elective angiography. The participants were randomly divided into two groups, including a pleasant natural sounds group, and a control group (n1/2 65 per group). Spielberger's state/trait anxiety inventory was used to assess levels of anxiety...
November 2016: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/27862904/baseline-blood-pressure-control-in-hispanics-characteristics-of-hispanics-in-the-systolic-blood-pressure-intervention-trial
#12
Carlos J Rodriguez, Carolyn H Still, Katelyn R Garcia, Lynne Wagenknecht, Suzanne White, Jeffrey T Bates, Margareth V Del Cid, Michael Lioudis, Nieves Lopez Barrera, Abel Moreyra, Henry Punzi, Robert J Ringer, William C Cushman, Gabriel Contreras, Karen Servilla, Michael Rocco
The Systolic Blood Pressure Intervention Trial (SPRINT) tested whether a systolic blood pressure (SBP) value <120 mm Hg reduces adverse clinical outcomes compared with the goal of <140 mm Hg. Here the authors describe the baseline characteristics of Hispanic participants in SPRINT. Nondiabetic hypertensive patients 50 years and older with SBP 130-180 mm Hg taking zero to four blood pressure (BP) medications were enrolled from the mainland United States and Puerto Rico. Cross-sectional, bivariate analysis was employed comparing sociodemographic and clinical factors in Hispanics vs non-Hispanics...
November 14, 2016: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/27858723/safety-and-improvement-of-movement-function-after-stroke-with-atomoxetine-a%C3%A2-pilot-randomized-trial
#13
Andrea Ward, Cheryl Carrico, Elizabeth Powell, Philip M Westgate, Laurie Nichols, Anne Fleischer, Lumy Sawaki
BACKGROUND: Intensive, task-oriented motor training has been associated with neuroplastic reorganization and improved upper extremity movement function after stroke. However, to optimize such training for people with moderate-to-severe movement impairment, pharmacological modulation of neuroplasticity may be needed as an adjuvant intervention. OBJECTIVE: Evaluate safety, as well as improvement in movement function, associated with motor training paired with a drug to upregulate neuroplasticity after stroke...
November 16, 2016: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/27849563/effect-of-intensive-versus-standard-clinic-based-hypertension-management-on-ambulatory-blood-pressure-results-from-the-sprint-systolic-blood-pressure-intervention-trial-ambulatory-blood-pressure-study
#14
Paul E Drawz, Nicholas M Pajewski, Jeffrey T Bates, Natalie A Bello, William C Cushman, Jamie P Dwyer, Lawrence J Fine, David C Goff, William E Haley, Marie Krousel-Wood, Andrew McWilliams, Dena E Rifkin, Yelena Slinin, Addison Taylor, Raymond Townsend, Barry Wall, Jackson T Wright, Mahboob Rahman
: The effect of clinic-based intensive hypertension treatment on ambulatory blood pressure (BP) is unknown. The goal of the SPRINT (Systolic Blood Pressure Intervention Trial) ambulatory BP ancillary study was to evaluate the effect of intensive versus standard clinic-based BP targets on ambulatory BP. Ambulatory BP was obtained within 3 weeks of the 27-month study visit in 897 SPRINT participants. Intensive treatment resulted in lower clinic systolic BP (mean difference between groups=16...
November 14, 2016: Hypertension
https://www.readbyqxmd.com/read/27824234/the-effects-of-upper-extremity-aerobic-exercise-on-exercise-capacity-and-other-health-issues-in-patients-with-spinal-cord-injury-a-randomized-controlled-study
#15
Halil Akkurt, Hale Uzumcugil Karapolat, Yesim Kirazli, Timur Kose
BACKGROUND: Immobility and secondary complications, including cardiopulmonary disease, pressure ulcers, and pain, occur in patients with spinal cord injury (SCI). These patients also have difficulty coping with the strain of daily activities. Thus, it is important for SCI patients to engage in aerobic exercise in order to be able to cope adequately with the strain of activities and SCI-related complications. AIM: The aim of this study was to investigate the effects of arm aerobic exercise on the parameters of cardiopulmonary function, quality of life, degree of disability, psychological state, and metabolic syndrome...
November 8, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27821598/home-and-online-management-and-evaluation-of-blood-pressure-home-bp-digital-intervention-for-self-management-of-uncontrolled-essential-hypertension-a-protocol-for-the-randomised-controlled-home-bp-trial
#16
Rebecca Band, Katherine Morton, Beth Stuart, James Raftery, Katherine Bradbury, Guiqing Lily Yao, Shihua Zhu, Paul Little, Lucy Yardley, Richard J McManus
INTRODUCTION: Self-management of hypertension, including self-monitoring and antihypertensive medication titration, lowers blood pressure (BP) at 1 year compared to usual care. The aim of the current trial is to assess the effectiveness of the Home and Online Management and Evaluation of Blood Pressure (HOME BP) intervention for the self-management of hypertension in primary care. METHODS AND ANALYSIS: The HOME BP trial will be a randomised controlled trial comparing BP self-management-consisting of the HOME BP online digital intervention with self-monitoring, lifestyle advice and antihypertensive drug titration-with usual care for people with uncontrolled essential hypertension...
November 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27802359/antihypertensive-withdrawal-for-the-prevention-of-cognitive-decline
#17
REVIEW
Susan Jongstra, Jennifer K Harrison, Terry J Quinn, Edo Richard
BACKGROUND: Clinical trials and observational data have variously shown a protective, harmful or neutral effect of antihypertensives on cognitive function. In theory, withdrawal of antihypertensives could improve cerebral perfusion and reduce or delay cognitive decline. However, it is also plausible that withdrawal of antihypertensives may have a detrimental effect on cognition through increased incidence of stroke or other vascular events. OBJECTIVES: To assess the effects of complete withdrawal of at least one antihypertensive medication on incidence of dementia, cognitive function, blood pressure and other safety outcomes in cognitively intact and cognitive impaired adults...
November 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27797709/whey-protein-lowers-blood-pressure-and-improves-endothelial-function-and-lipid-biomarkers-in-adults-with-prehypertension-and-mild-hypertension-results-from-the-chronic-whey2go-randomized-controlled-trial
#18
Ágnes A Fekete, Carlotta Giromini, Yianna Chatzidiakou, D Ian Givens, Julie A Lovegrove
BACKGROUND: Cardiovascular diseases (CVDs) are the greatest cause of death globally, and their reduction is a key public-health target. High blood pressure (BP) affects 1 in 3 people in the United Kingdom, and previous studies have shown that milk consumption is associated with lower BP. OBJECTIVE: We investigated whether intact milk proteins lower 24-h ambulatory blood pressure (AMBP) and other risk markers of CVD. DESIGN: The trial was a double-blinded, randomized, 3-way-crossover, controlled intervention study...
October 26, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27797708/randomized-clinical-trial-on-the-efficacy-of-hesperidin-2s-on-validated-cardiovascular-biomarkers-in-healthy-overweight-individuals
#19
Bouke N Salden, Freddy J Troost, Eric de Groot, Yala R Stevens, Marta Garcés-Rimón, Sam Possemiers, Bjorn Winkens, Ad A Masclee
BACKGROUND: Endothelial dysfunction (ED) is involved in the development of atherosclerosis. Hesperidin, a citrus flavonoid with antioxidant and other biological properties, potentially exerts beneficial effects on endothelial function (EF). OBJECTIVE: We investigated the effect of hesperidin 2S supplementation on EF in overweight individuals. DESIGN: This was a randomized, double-blind, placebo-controlled study in which 68 individuals were randomly assigned to receive hesperidin 2S (450 mg/d) or a placebo for 6 wk...
October 26, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27797683/short-term-effects-of-green-tea-on-blood-pressure-endothelial-function-and-metabolic-profile-in-obese-prehypertensive-women-a-crossover-randomized-clinical-trial
#20
Lívia de P Nogueira, José Firmino Nogueira Neto, Márcia R S T Klein, Antonio F Sanjuliani
BACKGROUND: Green tea consumption has been inversely associated with cardiovascular disease (CVD) in epidemiological studies. Although some interventional trials suggest that green tea has beneficial effects on CVD risk factors, such as hypertension and obesity, others have failed to show such benefits. AIMS: To evaluate the short-term effects of green tea on blood pressure, endothelial function, metabolic profile, and inflammatory activity in obese prehypertensive women...
October 31, 2016: Journal of the American College of Nutrition
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