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systolic blood pressure intervention trial

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https://www.readbyqxmd.com/read/28341688/global-cardiovascular-risk-assessment-in-the-primary-prevention-of-cardiovascular-disease-in-adults-systematic-review-of-systematic-reviews
#1
Dylan R J Collins, Alice C Tompson, Igho J Onakpoya, Nia Roberts, Alison M Ward, Carl J Heneghan
OBJECTIVE: To identify, critically appraise and summarise existing systematic reviews on the impact of global cardiovascular risk assessment in the primary prevention of cardiovascular disease (CVD) in adults. DESIGN: Systematic review of systematic reviews published between January 2005 and October 2016 in The Cochrane Library, EMBASE, MEDLINE or CINAHL databases, and post hoc analysis of primary trials. PARTICIPANTS, INTERVENTIONS, OUTCOMES: Systematic reviews of interventions involving global cardiovascular risk assessment relative to no formal risk assessment in adults with no history of CVD...
March 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28333551/effect-of-a-group-behavioural-management-program-on-emotional-regulation-of-food-choices-a-pilot-randomized-controlled-trial
#2
Danuta Southgate, Michelle Greiver, Greg Hubka, Kori Kostka, Rahim Moineddin, Marjan Moienedin, James Pencharz, Heather Bogetta, Claudia Mazariegos, Jo-Anne Guindon, Andrea Petroff
PURPOSE: In Ontario, group programs to increase mindfulness of food choices are provided in Family Health Teams (FHTs), but evaluation is limited. We targeted patients with chronic conditions that could benefit from intensified management and evaluated an existing program. METHODS: We included 3 FHTs. Patients were randomized to immediate participation in the intervention (n = 16) or to wait-list control (n = 14). Eligible participants were between 40 and 70 years old, living with diabetes and/or hypertension and had at least 2 of: elevated cholesterol (LDL >4 if hypertension or LDL >2 mmol/L if diabetes), blood sugar (A1c >7...
March 23, 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28333093/the-effect-of-regular-intake-of-dry-cured-ham-rich-in-bioactive-peptides-on-inflammation-platelet-and-monocyte-activation-markers-in-humans
#3
Sara María Martínez-Sánchez, Alfredo Minguela, David Prieto-Merino, María Pilar Zafrilla-Rentero, José Abellán-Alemán, Silvia Montoro-García
Background and aims: Dietary studies have shown that active biopeptides provide protective health benefits, although the mediating pathways are somewhat uncertain. To throw light on this situation, we studied the effects of consuming Spanish dry-cured ham on platelet function, monocyte activation markers and the inflammatory status of healthy humans with pre-hypertension. Methods: Thirty-eight healthy volunteers with systolic blood pressure of >125 mmHg were enrolled in a two-arm crossover randomized controlled trial...
March 23, 2017: Nutrients
https://www.readbyqxmd.com/read/28332506/effectiveness-of-home-blood-pressure-telemonitoring-a-systematic-review-and-meta-analysis-of-randomised-controlled-studies
#4
REVIEW
Y Duan, Z Xie, F Dong, Z Wu, Z Lin, N Sun, J Xu
To summarise evidence about the effectiveness of home blood pressure telemonitoring (HBPT) and identify the key components of intervention. We comprehensively searched PubMed, EMBASE and the Cochrane Library for relevant studies. The authors were contacted for additional information. Two authors independently extracted the data and assessed the risk of bias. 46 randomised controlled trials including a total of 13 875 cases were identified. Compared with usual care, HBPT improved office systolic blood pressure (BP) and diastolic BP by 3...
March 23, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28320409/can-an-incentive-based-intervention-increase-physical-activity-and-reduce-sitting-among-adults-the-achieve-active-choices-incentive-feasibility-study
#5
Kylie Ball, Ruth F Hunter, Jaimie-Lee Maple, Marj Moodie, Jo Salmon, Kok-Leong Ong, Lena D Stephens, Michelle Jackson, David Crawford
BACKGROUND: Despite recent interest in the potential of incentivisation as a strategy for motivating healthier behaviors, little remains known about the effectiveness of incentives in promoting physical activity and reducing sedentary behavior, and improving associated health outcomes. This pre-post-test design study investigated the feasibility, appeal and effects of providing non-financial incentives for promoting increased physical activity, reduced sedentary time, and reduced body mass index (BMI) and blood pressure among inactive middle-aged adults...
March 21, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28319596/medium-term-effects-of-dietary-nitrate-supplementation-on-systolic-and-diastolic-blood-pressure-in-adults-a-systematic-review-and-meta-analysis
#6
Ammar W Ashor, Jose Lara, Mario Siervo
OBJECTIVES: Dietary nitrate supplementation has been shown to lower blood pressure (BP) particularly in short-term clinical trials. Whether these effects are sustained in the long-term remains to be established. The objective was to conduct a meta-analysis of randomized controlled trials that examined whether dietary nitrate supplementation for more than 1 week has beneficial effects on SBP and DBP. METHODS: Electronic databases were searched from inception until May 2016...
March 17, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28302601/dairy-consumption-systolic-blood-pressure-and-risk-of-hypertension-mendelian-randomization-study
#7
Ming Ding, Tao Huang, Helle Km Bergholdt, Børge G Nordestgaard, Christina Ellervik, Lu Qi
Objective To examine whether previous observed inverse associations of dairy intake with systolic blood pressure and risk of hypertension were causal.Design Mendelian randomization study using the single nucleotide polymorphism rs4988235 related to lactase persistence as an instrumental variable.Setting CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Consortium.Participants Data from 22 studies with 171 213 participants, and an additional 10 published prospective studies with 26 119 participants included in the observational analysis...
March 16, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28290160/risk-scoring-for-the-primary-prevention-of-cardiovascular-disease
#8
REVIEW
Kunal N Karmali, Stephen D Persell, Pablo Perel, Donald M Lloyd-Jones, Mark A Berendsen, Mark D Huffman
BACKGROUND: The current paradigm for cardiovascular disease (CVD) emphasises absolute risk assessment to guide treatment decisions in primary prevention. Although the derivation and validation of multivariable risk assessment tools, or CVD risk scores, have attracted considerable attention, their effect on clinical outcomes is uncertain. OBJECTIVES: To assess the effects of evaluating and providing CVD risk scores in adults without prevalent CVD on cardiovascular outcomes, risk factor levels, preventive medication prescribing, and health behaviours...
March 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28270757/effectiveness-of-a-novel-qigong-meditative-movement-practice-for-impaired-health-in-flight-attendants-exposed-to-second-hand-cigarette-smoke
#9
Peter Payne, Steven Fiering, James C Leiter, David T Zava, Mardi A Crane-Godreau
This single-arm non-randomized pilot study explores an intervention to improve the health of flight attendants (FA) exposed to second-hand cigarette smoke prior to the smoking ban on commercial airlines. This group exhibits an unusual pattern of long-term pulmonary dysfunction. We report on Phase I of a two-phase clinical trial; the second Phase will be a randomized controlled trial testing digital delivery of the intervention. Subjects were recruited in the Northeastern US; testing and intervention were administered in 4 major cities...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28267470/rationale-and-design-of-a-cluster-randomized-controlled-trial-to-evaluate-the-effects-of-a-community-health-worker-based-program-for-cardiovascular-risk-factor-control-in-india
#10
Aditya Khetan, Raghunandan Purushothaman, Melissa Zullo, Rishab Gupta, Vittal Hejjaji, Sushil Agarwal, Sri Krishna Madan Mohan, Richard Josephson
BACKGROUND: The increasing burden of cardiovascular disease (CVD) in low- and middle-income countries is largely driven by the increasing prevalence of hypertension, diabetes, and tobacco use. We hypothesize that the utilization of community health workers (CHWs) to screen for and manage these 3 determinants of CVD in an integrated manner would be an effective approach to favorably affecting public health. METHODS: We have designed and set up the infrastructure to implement a 2-year community-based cluster randomized controlled trial in an underserved region of West Bengal, India...
March 2017: American Heart Journal
https://www.readbyqxmd.com/read/28263370/fixed-dose-combination-therapy-for-the-prevention-of-atherosclerotic-cardiovascular-diseases
#11
REVIEW
Ehete Bahiru, Angharad N de Cates, Matthew Rb Farr, Morag C Jarvis, Mohan Palla, Karen Rees, Shah Ebrahim, Mark D Huffman
BACKGROUND: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and disability worldwide, yet ASCVD risk factor control and secondary prevention rates remain low. A fixed-dose combination of blood pressure- and cholesterol-lowering and antiplatelet treatments into a single pill, or polypill, has been proposed as one strategy to reduce the global burden of ASCVD. OBJECTIVES: To determine the effect of fixed-dose combination therapy on all-cause mortality, fatal and non-fatal ASCVD events, and adverse events...
March 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28257392/prehospital-hypertonic-fluid-resuscitation-for-trauma-patients-a-systematic-review-and-meta-analysis
#12
Claire de Crescenzo, Farzam Gorouhi, Edgardo S Salcedo, Joseph M Galante
BACKGROUND: Prehospital assessment of a patient's circulation status and appropriate resuscitation with intravenous fluids plays a critical role in patients with obvious hemorrhage or systolic blood pressure below 90 mmHg. OBJECTIVES: We assessed the efficacy and safety of prehospital administration of crystalloids, or colloids to improve the survival rate of trauma patients with acceptable safety profile. DATA SOURCES: We searched SCOPUS, Embase, TRIP database, Cochrane Central Register of Controlled Trials, Ovid MEDLINE, and PubMed as per search protocol from 1 January 1900 to 12 February 2015...
March 2, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28247026/one-night-of-partial-sleep-deprivation-impairs-recovery-from-a-single-exercise-training-session
#13
Dale E Rae, Tayla Chin, Kagiso Dikgomo, Lee Hill, Andrew J McKune, Tertius A Kohn, Laura C Roden
PURPOSE: The effects of sleep deprivation on physical performance are well documented, but data on the consequence of sleep deprivation on recovery from exercise are limited. The aim was to compare cyclists' recovery from a single bout of high-intensity interval training (HIIT) after which they were given either a normal night of sleep (CON, 7.56 ± 0.63 h) or half of their usual time in bed (DEP, 3.83 ± 0.33 h). METHODS: In this randomized cross-over intervention study, 16 trained male cyclists (age 32 ± 7 years), relative peak power output (PPO 4...
February 28, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28245085/effect-on-cardiovascular-disease-risk-factors-of-interventions-to-alter-consultations-between-practitioners-and-patients-with-type-2-diabetes-a-systematic-review-and-meta-analysis-of-trials-in-primary-care
#14
REVIEW
Hajira Dambha-Miller, Andrew J M Cooper, Ann Louise Kinmonth, Simon J Griffin
OBJECTIVE: To examine the effect on cardiovascular (CVD) risk factors of interventions to alter consultations between practitioners and patients with type 2 diabetes. SEARCH STRATEGY: Electronic and manual citation searching to identify relevant randomized controlled trials (RCTs). INCLUSION CRITERIA: RCTs that compared usual care to interventions to alter consultations between practitioners and patients. The population was adults aged over 18 years with type 2 diabetes...
February 28, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28236927/systematic-review-and-meta-analysis-of-postcarotid-endarterectomy-hypertension-after-eversion-versus-conventional-carotid-endarterectomy
#15
REVIEW
Serdar Demirel, Käthe Goossen, Hans Bruijnen, Pascal Probst, Dittmar Böckler
OBJECTIVE: Blood pressure (BP) instability after carotid endarterectomy (CEA) is a risk factor for cerebrovascular and cardiovascular complications. The role of the operative technique in the development of post-CEA hemodynamic instability is unclear. The primary goal of this study was to systematically review the literature to determine whether hypertension in the early postoperative period is dependent on the surgical technique used. METHODS: We searched MEDLINE, Cochrane CENTRAL, and Web of Science through June 2016 without restrictions to language or starting date...
March 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28230063/effects-of-calcium-plus-vitamin-d-supplementation-on-blood-pressure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
L Wu, D Sun
The effect of calcium or vitamin D supplement on blood pressure (BP) has been explored in previous meta-analyses, but the results are conflicting. The combined efficacy of calcium and vitamin D on BP has not been systematically assessed. Thus, we conducted a meta-analysis of randomized controlled trials (RCTs) to explore the effect of calcium plus vitamin D (CaD) supplementation on changes of systolic blood pressure (SBP) and diastolic blood pressure among male and female participants (with and without diagnosed hypertension) aged 18 years or older...
February 23, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28224720/pyridostigmine-bromide-versus-fludrocortisone-in-the-treatment-of-orthostatic-hypotension-in-parkinson-s-disease-a-randomized-controlled-trial
#17
S R Schreglmann, F Büchele, M Sommerauer, L Epprecht, G Kägi, S Hägele-Link, O Götze, L Zimmerli, D Waldvogel, C R Baumann
BACKGROUND AND PURPOSE: Evidence for effective treatment options for orthostatic hypotension (OH) in Parkinson's disease (PD) is scarce. Elevation of cholinergic tone with pyridostigmine bromide has been reported as a way to improve blood pressure (bp) regulation in neurogenic hypotension without causing supine hypertension. METHODS: This was a double-centre, double-blind, randomized, active-control, crossover, phase II non-inferiority trial of pyridostigmine bromide for OH in PD (clinicaltrials...
February 22, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28219804/the-immediate-cardiovascular-response-to-joint-mobilization-of-the-neck-a-randomized-placebo-controlled-trial-in-pain-free-adults
#18
Emmanuel Y Yung, Cheongeun Oh, Michael S Wong, Jason K Grimes, Erica M Barton, Muhammad I Ali, David Cameron
BACKGROUND: Some normotensive patients can have a spike in resting systolic blood pressure (SBP) in response to acute neck pain. Applying the typical dosage of mobilization may potentially result in a sympatho-excitatory response, further increasing resting SBP. Therefore, there is a need to explore other dosage regimens that could result in a decrease in SBP. OBJECTIVES: To compare the blood pressure (BP) and heart rate (HR) response of pain-free, normotensive adults when receiving unilateral posterior-to-anterior mobilization (PA) applied to the neck versus its corresponding placebo (PA-P)...
April 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28217594/effectiveness-of-yoga-program-in-the-management-of-diabetes-using-community-health-workers-in-the-urban-slums-of-bangalore-city-a-non-randomized-controlled-trial
#19
Hemavathi Dasappa, Farah Naaz Fathima, Rugmani Prabhakar
TRIAL DESIGN: Nonrandomized controlled trial. METHODS: Nonrandomized controlled trial. This was an interventional study that was conducted in 4 slums of Bengaluru. Of the 256 diabetes participants, only 109 people agreed to participate in the program. Of 109 people, 52 people agreed to participate in the intervention (agreed to learn and practice Yoga) while the remaining 57 people were assigned to nonintervention group. Randomization and blinding could not be done...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28212320/a-mediterranean-diet-to-improve-cardiovascular-and-cognitive-health-protocol-for-a-randomised-controlled-intervention-study
#20
Alexandra T Wade, Courtney R Davis, Kathryn A Dyer, Jonathan M Hodgson, Richard J Woodman, Hannah A D Keage, Karen J Murphy
The Mediterranean diet has demonstrated efficacy for improving cardiovascular and cognitive health. However, a traditional Mediterranean diet delivers fewer serves of dairy and less dietary calcium than is currently recommended in Australia, which may limit long-term sustainability. The present study aims to evaluate whether a Mediterranean diet with adequate dairy and calcium can improve cardiovascular and cognitive function in an at-risk population, and thereby reduce risk of cardiovascular disease (CVD) and cognitive decline...
February 16, 2017: Nutrients
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