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systolic blood pressure intervention trial

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https://www.readbyqxmd.com/read/29152243/effect-of-pomegranate-extract-on-blood-pressure-and-anthropometry-in-adults-a-double-blind-placebo-controlled-randomised-clinical-trial
#1
A Stockton, G Farhat, Gordon J McDougall, E A S Al-Dujaili
Pomegranate (Punica granatum), a polyphenol-rich fruit, has been suggested to reduce cardiovascular risk due to its antioxidant properties. Hypertension and obesity are the most preventable cardiovascular risk factors. Few studies on blood pressure and/or body-weight status have been conducted in human subjects. Previous investigations have tended to focus on pomegranate juice. The aim of the present study was to investigate the effect of pomegranate extract (PE) on blood pressure and anthropometric measures in adults with no symptomatic disease...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29147120/a-comparative-study-of-the-effect-of-green-tea-and-sour-tea-on-blood-pressure-and-lipid-profile-in-healthy-adult-men
#2
Marzieh Kafeshani, Mohammad Hasan Entezari, Jahangir Karimian, Makan Pourmasoumi, Mohammad Reza Maracy, Mohammad Reza Amini, Amir Hadi
BACKGROUND: Cardiovascular diseases (CVD) are a set of metabolic disorders affecting heart and blood vessels. Green tea and sour tea (Hibiscus sabdariffa L.) have attracted significant attention recently due to their high popularity, nutrient profile and therapeutic effects. The aim of the present study was to compare the effects of green tea and sour tea supplementation on blood pressure and lipid profile in healthy adult men. METHODS: This randomized, double-blind, placebo-controlled trial included 54 healthy adult men...
May 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29141968/the-nitrate-independent-blood-pressure-lowering-effect-of-beetroot-juice-a-systematic-review-and-meta-analysis
#3
REVIEW
Zahra Bahadoran, Parvin Mirmiran, Ali Kabir, Fereidoun Azizi, Asghar Ghasemi
Beetroot is considered a complementary treatment for hypertension because of its high content of inorganic NO3 This systematic review and meta-analysis aimed to clarify several aspects of beetroot juice supplementation on systolic blood pressure (SBP) and diastolic blood pressure (DBP). We searched PubMed, Scopus, and Embase databases, and the reference lists of previous reviews. Randomized clinical trials that investigated the effects of beetroot juice on resting blood pressure in humans were recruited for quality assessment, meta-analyses, subgroup analyses, and meta-regressions; of these, 22 were conducted between 2009 and 2017 and included a total of 47 intervention (n = 650) and 43 control (n = 598) groups...
November 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/29141784/effects-of-sodium-reduction-and-the%C3%A2-dash%C3%A2-diet-in-relation-to-baseline%C3%A2-blood-pressure
#4
Stephen P Juraschek, Edgar R Miller, Connie M Weaver, Lawrence J Appel
BACKGROUND: Both sodium reduction and the DASH (Dietary Approaches to Stop Hypertension) diet, a diet rich in fruits, vegetables, and low-fat dairy products, and reduced in saturated fat and cholesterol, lower blood pressure. The separate and combined effects of these dietary interventions by baseline blood pressure (BP) has not been reported. OBJECTIVES: The authors compared the effects of low versus high sodium, DASH versus control, and both (low sodium-DASH vs...
November 4, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29140556/withdrawn-transcendental-meditation-for-the-primary-prevention-of-cardiovascular-disease
#5
REVIEW
Louise Hartley, Angelique Mavrodaris, Nadine Flowers, Edzard Ernst, Karen Rees
BACKGROUND: A major determinant in cardiovascular disease (CVD) is stress. As transcendental meditation (TM) is thought to help in lowering negative stress indicators, it may be a beneficial strategy for the primary prevention of CVD. OBJECTIVES: To determine the effectiveness of TM for the primary prevention of CVD. SEARCH METHODS: We searched the following electronic databases: the Cochrane Central Register of Controlled Trials (CENTRAL) (2013, Issue 10); MEDLINE (Ovid) (1946 to week three November 2013); EMBASE Classic and EMBASE (Ovid) (1947 to week 48 2013); ISI Web of Science (1970 to 28 November 2013); and Database of Abstracts of Reviews of Effects (DARE) and Health Technology Assessment Database and Health Economics Evaluations Database (November 2013)...
November 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29137055/efficacy-of-tai-chi-and-qigong-for-the-prevention-of-stroke-and-stroke-risk-factors-a-systematic-review-with-meta-analysis
#6
Romy Lauche, Wenbo Peng, Caleb Ferguson, Holger Cramer, Jane Frawley, Jon Adams, David Sibbritt
BACKGROUND: This review aims to summarize the evidence of Tai Chi and qigong interventions for the primary prevention of stroke, including the effects on populations with major stroke risk factors. METHODS: A systematic literature search was conducted on January 16, 2017 using the PubMed, Scopus, Cochrane Library, and CINAHL databases. Randomized controlled trials examining the efficacy of Tai Chi or qigong for stroke prevention and stroke risk factors were included...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29133606/effects-of-bariatric-surgery-in-obese-patients-with-hypertension-the-gateway-randomized-trial-gastric-bypass-to-treat-obese-patients-with-steady-hypertension
#7
Carlos Aurelio Schiavon, Angela Cristine Bersch-Ferreira, Eliana Vieira Santucci, Juliana Dantas Oliveira, Camila Ragne Torreglosa, Priscila Torres Bueno, Julia Caldas Frayha, Renato Nakagawa Santos, Lucas Petri Damian, Patricia Malvina Noujaim, Helio Halpern, Frederico L J Monteiro, Ricardo Vitor Cohen, Carlos H Uchoa, Marcio Gonçalves de Souza, Celso Amodeo, Luiz Bortolotto, Dimas Ikeoka, Luciano F Drager, Alexandre Biasi Cavalcanti, Otavio Berwanger
BACKGROUND : Recent research efforts on bariatric surgery have focused on metabolic and diabetes mellitus resolution. Randomized trials designed to assess the impact of bariatric surgery in patients with obesity and hypertension are needed. METHODS : In this randomized, single-center, nonblinded trial, we included patients with hypertension (using ≥2 medications at maximum doses or >2 at moderate doses) and a body mass index between 30.0 and 39.9 kg/m(2) Patients were randomized to Roux-en-Y gastric bypass plus medical therapy or medical therapy alone...
November 13, 2017: Circulation
https://www.readbyqxmd.com/read/29133522/systolic-blood-pressure-response-in-sprint-systolic-blood-pressure-intervention-trial-and-accord-action-to-control-cardiovascular-risk-in-diabetes-a-possible-explanation-for-discordant-trial-results
#8
Chenxi Huang, Sanket S Dhruva, Andreas C Coppi, Frederick Warner, Shu-Xia Li, Haiqun Lin, Khurram Nasir, Harlan M Krumholz
BACKGROUND: SPRINT (Systolic Blood Pressure Intervention Trial) and the ACCORD (Action to Control Cardiovascular Risk in Diabetes) blood pressure trial used similar interventions but produced discordant results. We investigated whether differences in systolic blood pressure (SBP) response contributed to the discordant trial results. METHODS AND RESULTS: We evaluated the distributions of SBP response during the first year for the intensive and standard treatment groups of SPRINT and ACCORD using growth mixture models...
November 13, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29125633/usability-of-functional-mri-in-clinical-studies-for-fast-and-reliable-assessment-of-renal-perfusion-and-quantification-of-hemodynamic-effects-on-the-kidney
#9
Tobias Getzin, Marcus May, Martina Schmidbauer, Marcel Gutberlet, Petros Martirosian, Reinhard Oertel, Frank Wacker, Christoph Schindler, Katja Hueper
The purpose of this study was to evaluate contrast-media-free arterial spin labeling, a technique of functional magnetic resonance imaging (MRI), for assessment of kidney perfusion in a clinical study. We examined renal perfusion by arterial spin labeling in 15 healthy adults using a clinical 1.5-T MRI system, twice under baseline conditions and 60 minutes after a single oral dose of 50 mg captopril. Data evaluation included assessment of interstudy and interrater reproducibility in addition to the pharmacological effect of captopril on kidney perfusion and a sample size calculation for potential application of the technique in pharmacological intervention studies...
November 10, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29122253/the-effect-of-nature-sounds-on-physiological-indicators-among-patients-in-the-cardiac-care-unit
#10
Tahereh Najafi Ghezeljeh, Maryam Nasari, Hamid Haghani, Habiballah Rezaei Loieh
BACKGROUND AND OBJECTIVES: Environmental noises may create physiological and psychological disorders in patients hospitalized in the CCU. Therefore, this study was conducted to investigate the effects of nature sounds on physiological indicators among patients in the CCU. MATERIALS & METHODS: This randomized clinical trial was conducted on 93 patients hospitalized in the cardiac care units of three teaching hospitals in 2016. The patients were selected using the convenient method with three randomized blocks...
November 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29108664/the-effect-of-acute-and-7-days-dietary-nitrate-on-mechanical-efficiency-exercise-performance-and-cardiac-biomarkers-in-patients-with-chronic-obstructive-pulmonary-disease
#11
Rosanne J H C G Beijers, Stephanie M D Huysmans, Coby van de Bool, Boris R M Kingma, Lex B Verdijk, Luc J C van Loon, Steven J R Meex, Harry R Gosker, Annemie M W J Schols
BACKGROUND & AIMS: Many COPD patients have a reduced exercise capacity and mechanical efficiency and are at increased cardiometabolic risk. This study aimed to assess acute and 7-days effects of dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with COPD. METHODS: This double-blind, randomized cross-over placebo controlled trial included 20 mild-to-moderate COPD patients (66.6 ± 7.5 years) with moderate exercise impairments and decreased mechanical efficiency, normal BMI (26 ± 3 kg/m(2)) but high prevalence of abdominal obesity (83...
October 31, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29105295/the-effect-of-berry-based-food-interventions-on-markers-of-cardiovascular-and-metabolic-health-a-systematic-review-of-randomised-controlled-trials
#12
REVIEW
Clara Heneghan, Mairead Kiely, Jacqueline Lyons, Alice Lucey
SCOPE: Epidemiological evidence, animal and in vitro studies suggest that berry consumption may ameliorate markers of cardiovascular disease (CVD). The aim of this systematic review was to evaluate findings from berry-based randomised controlled trials (RCTs) to establish the effects of berry consumption on markers of cardiovascular and metabolic health. METHODS AND RESULTS: PubMed and Web of Science were searched for RCTs investigating berry consumption on CVD risk outcomes in adults...
November 3, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29101186/bp-reduction-kidney-function-decline-and-cardiovascular-events-in-patients-without-ckd
#13
Rita Magriço, Miguel Bigotte Vieira, Catarina Viegas Dias, Lia Leitão, João Sérgio Neves
BACKGROUND AND OBJECTIVES: In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive systolic BP treatment (target <120 mm Hg) was associated with fewer cardiovascular events and higher incidence of kidney function decline compared with standard treatment (target <140 mm Hg). We evaluated the association between mean arterial pressure reduction, kidney function decline, and cardiovascular events in patients without CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We categorized patients in the intensive treatment group of the SPRINT according to mean arterial pressure reduction throughout follow-up: <20, 20 to <40, and ≥40 mm Hg...
November 3, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29100199/development-and-evaluation-of-a-nurse-led-hypertension-management-model-a-randomized-controlled-trial
#14
Xuejiao Zhu, Frances Kam Yuet Wong, Candy Lai Har Wu
BACKGROUND: The hypertension prevalence rate is increasing but the control rate is unsatisfactory. Nurse-led healthcare may be an effective way to improve outcomes for hypertensive patients but more evidence is required especially at the community level. OBJECTIVE: This study aims to establish a nurse-led hypertension management model and to test its effectiveness at the community level. DESIGN: A single-blind, randomized controlled trial was performed in an urban community healthcare center in China...
October 13, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29094434/autonomy-supportive-web-based-lifestyle-modification-for-cardiometabolic-risk-in-postmenopausal-women-randomized-trial
#15
Hye-Ryoung Kim, Hee-Seung Kim
The management of cardiometabolic risk factors, such as abdominal obesity, dyslipidemia, hypertension, and hyperglycemia, is essential for the health of postmenopausal women. In this study, we identified the effects of autonomy-supportive, Web-based lifestyle modification for the management cardiometabolic risk of postmenopausal women, and assessed the mediation effect of intrinsic motivation. This study was a randomized trial involving 71 postmenopausal Korean women. For the intervention group, we provided the Web-based autonomy supports for 12 weeks; however, for the control group, individual consultations on healthy lifestyle was conducted at the first meeting...
November 2, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/29080572/clinical-update-on-nursing-home-medicine-2017
#16
Barbara J Messinger-Rapport, Milta O Little, John E Morley, Julie K Gammack
This is the 11th annual Clinical Update from the AMDA meeting article. This year the topics covered are hypertension after the Systolic Blood Pressure Intervention Trial; chronic obstructive pulmonary disease risk factors, diagnosis and management including end-of-life planning, and the difficulties with exacerbations such as breathlessness; diagnosis and treatment of cognitive impairment and dementia; and wound care and pressure ulcer management.
November 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29079252/effect-of-an-intensified-multifactorial-intervention-on-cardiovascular-outcomes-and-mortality-in-type-2-diabetes-j-doit3-an-open-label-randomised-controlled-trial
#17
Kohjiro Ueki, Takayoshi Sasako, Yukiko Okazaki, Masayuki Kato, Sumie Okahata, Hisayuki Katsuyama, Mikiko Haraguchi, Ai Morita, Ken Ohashi, Kazuo Hara, Atsushi Morise, Kazuo Izumi, Naoki Ishizuka, Yasuo Ohashi, Mitsuhiko Noda, Takashi Kadowaki
BACKGROUND: Limited evidence suggests that multifactorial interventions for control of glucose, blood pressure, and lipids reduce macrovascular complications and mortality in patients with type 2 diabetes. However, safe and effective treatment targets for these risk factors have not been determined for such interventions. METHODS: In this multicentre, open-label, randomised, parallel-group trial, undertaken at 81 clinical sites in Japan, we randomly assigned (1:1) patients with type 2 diabetes aged 45-69 years with hypertension, dyslipidaemia, or both, and an HbA1c of 6·9% (52·0 mmol/mol) or higher, to receive conventional therapy for glucose, blood pressure, and lipid control (targets: HbA1c <6·9% [52·0 mmol/mol], blood pressure <130/80 mm Hg, LDL cholesterol <120 mg/dL [or 100 mg/dL in patients with a history of coronary artery disease]) or intensive therapy (HbA1c <6·2% [44·3 mmol/mol], blood pressure <120/75 mm Hg, LDL cholesterol <80 mg/dL [or 70 mg/dL in patients with a history of coronary artery disease])...
October 24, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29071755/effect-of-aromatherapy-massage-on-anxiety-depression-and-physiologic-parameters-in-older-patients-with-the-acute-coronary-syndrome-a-randomized-clinical-trial
#18
Tahereh Bahrami, Nahid Rejeh, Majideh Heravi-Karimooi, Mojtaba Vaismoradi, Seyed Davood Tadrisi, Christina Sieloff
PURPOSE: This study aimed to investigate the effect of aromatherapy massage on anxiety, depression, and physiologic parameters in older patients with acute coronary syndrome. METHODS: This randomized controlled trial was conducted on 90 older women with acute coronary syndrome. The participants were randomly assigned into the intervention and control groups (n = 45). The intervention group received reflexology with lavender essential oil, but the control group only received routine care...
October 25, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29057545/modelling-incremental-benefits-on-complications-rates-when-targeting-lower-hba1c-levels-in-people-with-type-2-diabetes-and-cardiovascular-disease
#19
S A Mostafa, R L Coleman, O F Agbaje, A M Gray, R R Holman, M A Bethel
AIM: Glucose-lowering interventions in Type 2 diabetes mellitus have demonstrated reductions in microvascular complications and modest reductions in macrovascular complications. However, the degree to which targeting different HbA1c reductions might reduce risk is unclear. METHODS: Participant-level data for Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) participants with established cardiovascular disease were used in a Type 2 diabetes-specific simulation model to quantify the likely impact of different HbA1c decrements on complication rates...
October 23, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29046405/potato-consumption-does-not-increase-blood-pressure-or-incident-hypertension-in-2-cohorts-of-spanish-adults
#20
Emily A Hu, Miguel A Martínez-González, Jordi Salas-Salvadó, Dolores Corella, Emilio Ros, Montse Fitó, Antonio Garcia-Rodriguez, Ramon Estruch, Fernando Arós, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Xavier Pintó, Miguel Ruiz-Canela, Cristina Razquin, Mònica Bulló, José V Sorlí, Helmut Schröder, Casey M Rebholz, Estefania Toledo
Background: Potatoes have a high glycemic load but also antioxidants, vitamins, and minerals. It is unclear what mechanisms are involved in relation to their effect on blood pressure (BP) and hypertension.Objectives: This study aimed to assess the association between potato consumption, BP changes, and the risk of hypertension in 2 Spanish populations.Methods: Separate analyses were performed in PREDIMED (PREvención con DIeta MEDiterránea), a multicenter nutrition intervention trial of adults aged 55-80 y, and the SUN (Seguimiento Universidad de Navarra) project, a prospective cohort made up of university graduates and educated adults with ages (means ± SDs) of 42...
October 18, 2017: Journal of Nutrition
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