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https://www.readbyqxmd.com/read/29046120/aflatoxins-and-ochratoxin-a-in-flour-a-survey-of-the-serbian-retail-market
#1
Ljilja Torović
This report presents data on the occurrence of aflatoxins and ochratoxin A in different types of flour marketed in Serbia. A total of 114 samples of wheat, buckwheat, rye, oat, barley, rice, millet and corn flours was collected in the period 2012-2016 and analysed using high performance liquid chromatography with fluorescence detection. Among flours other than corn, aflatoxin B1 was quantified only in rice, while OTA was found in 29% of the samples. In corn flours the percentage of positive samples varied greatly over the years: AFB1 7...
October 19, 2017: Food Additives & Contaminants. Part B, Surveillance
https://www.readbyqxmd.com/read/29036518/are-prothrombotic-mutations-a-time-to-event-risk-factor
#2
Branko V Tomic, Maja Z Gvozdenov, Iva B Pruner, Jelena M Simic, Mirjana K Kovac, Dragica P Radojkovic, Valentina J Djordjevic
Background: Deep vein thrombosis (DVT) represents a common disorder involving genetic and acquired risk factors. It has been proposed that acquired risk factors are more important with aging than genetic factors, indicating different prevalence of prothrombotic mutations throughout the lifespan. Objective: To determine the role of the most frequent prothrombotic genetic risk factors (Factor V [FV] Leiden and Factor II [FII] G20210A mutations) in first-time DVT etiology in patients of different ages...
September 23, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/29017835/two-goitrogenic-1-3-oxazolidine-2-thione-derivatives-from-brassicales-taxa-challenging-identification-occurrence-and-immunomodulatory-effects
#3
Niko S Radulović, Milica M Todorovska, Dragan B Zlatković, Nikola M Stojanović, Pavle J Randjelović
1,3-Oxazolidine-2-thione derivatives are glucosinolate-related food constituents known to impart (thyreo)toxic properties to some cruciferous vegetables. In this work, 5,5-dimethyl-1,3-oxazolidine-2-thione and (-)-(R)-5-phenyl-1,3-oxazolidine-2-thione, known goitrogens, were isolated from Draba lasiocarpa Rochel (Brassicaceae) and Reseda luteola L. (Resedaceae), respectively, and were fully spectrally characterized. Subsequently, the occurrence of the two 1,3-oxazolidine-2-thiones was verified in six additional taxa out of in total 78 screened Serbian Brassicales taxa...
October 7, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28980831/the-hexaco-personality-inventory-validation-and-psychometric-properties-in-the-serbian-language
#4
Janko Međedović, Petar Čolović, Bojana M Dinić, Snežana Smederevac
The aim of this research is to validate the HEXACO model of personality in the Serbian language through psychometric validation of the 100-item version of the HEXACO-PI-R. The research was conducted on 2 independent samples, the first comprising 1,217 participants from a community sample (55.5% females; average age = 31.77 years), and the second 345 undergraduate students (65% females; average age = 21 years). Besides the HEXACO-PI-R, 2 questionnaires were applied for the purposes of convergent validation: the Big Five Plus Two (BF+2), measuring 7 lexical personality dimensions (applied in Sample 1), and the Big Five Inventory (BFI; applied in Sample 2)...
October 5, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/28958832/gch1-mutations-are-common-in-serbian-patients-with-dystonia-parkinsonism-challenging-previously-reported-prevalence%C3%A2-rates-of-dopa-responsive-dystonia
#5
Valerija Dobričić, Aleksandra Tomić, Vesna Branković, Nikola Kresojević, Milena Janković, Ana Westenberger, Vedrana Milić Rašić, Christine Klein, Ivana Novaković, Marina Svetel, Vladimir S Kostić
BACKGROUND: GTP cyclohydrolase 1-deficient DOPA-responsive dystonia, caused by autosomal dominant mutation in the gene coding for GTP cyclohydrolase 1, is a rare disorder with a reported prevalence of 0.5 per million. A correct diagnosis of DRD is crucial, given that this is an exquisitely treatable neurogenetic disorder. Although genetic testing is now widely available, we hypothesize that DRD is still underdiagnosed and its prevalence underestimated. METHODS: Molecular genetic analysis of the GCH1 gene was performed in a representative cohort of 47 Serbian patients with clinical features of DRD and in their 16 available relatives...
September 18, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28949773/gene-gene-interactions-between-glutathione-s-transferase-m1-and-matrix-metalloproteinases-1-9-and-12-in-chronic-obstructive-pulmonary-disease-in-serbians
#6
Marija Stankovic, Aleksandra Nikolic, Ljudmila Nagorni-Obradovic, Natasa Petrovic-Stanojevic, Dragica Radojkovic
Chronic obstructive pulmonary disease (COPD) is a complex disorder influenced by multiple genetic and environmental factors, as well as their interactions. Since elevated oxidative stress and protease activity characterize the pathogenesis of COPD, variants of genes that can affect these processes have been commonly studied in COPD. However, interactions among genes that can influence oxidative stress and protease activity remain poorly investigated in COPD. The aim of this study was to look into the role of functional variants in matrix metalloproteinases (MMPs) 1, 9, and 12 in the occurrence and/or modulation of COPD, and to analyze their interactions with glutathione S-transferases (GSTs) M1, T1, and P1 in the pathogenesis of COPD in Serbians...
September 26, 2017: COPD
https://www.readbyqxmd.com/read/28942489/molecular-genetic-and-clinical-characterization-of-myotonic-dystrophy-type-1-patients-carrying-variant-repeats-within-dmpk-expansions
#7
Jovan Pešović, S Perić, M Brkušanin, G Brajušković, V Rakočević-Stojanović, Dušanka Savić-Pavićević
Myotonic dystrophy type 1 (DM1) is caused by a highly unstable expansion of CTG repeats in the DMPK gene. Its huge phenotypic variability cannot be explained solely by the repeat number. Recently, variant repeats within the DMPK expansions have emerged as potential disease modifiers. The frequency of variant expanded alleles was estimated in 242 DM1 patients from 174 Serbian families using repeat-primed PCR (RP-PCR). The patterns of variant repeats were determined by direct sequencing of RP-PCR or PCR products...
September 23, 2017: Neurogenetics
https://www.readbyqxmd.com/read/28926634/nasal-and-pharyngeal-carriage-of-methicillin-resistant-staphylococcus-sciuri-among-hospitalised-patients-and-healthcare-workers-in-a-serbian-university-hospital
#8
Ivana Cirkovic, Jasmina Trajkovic, Tomasz Hauschild, Paal Skytt Andersen, Adebayo Shittu, Anders Rhod Larsen
There has been a paucity of data on methicillin-resistant Staphylococcus sciuri (MRSS) epidemiology in European healthcare settings. The aim of the study was to determine the prevalence of nasal and pharyngeal carriage and diversity of MRSS among inpatients and healthcare workers (HCWs) in the largest healthcare centre in Serbia, and to assess performance of different methods for MRSS screening. Nasal and pharyngeal swabs were obtained from 195 patients and 105 HCWs in different departments. Each swab was inoculated directly onto MRSA-ID, oxacillin-resistance screening agar and mannitol salt agar (MSA) with 2 mg/L of oxacillin...
2017: PloS One
https://www.readbyqxmd.com/read/28924541/the-lrp1-gene-polymorphism-is-associated-with-increased-risk-of-metabolic-syndrome-prevalence-in-the-serbian-population
#9
N Vučinić, E Stokić, I Djan, D Obreht, N Veličković, K Stankov, M Djan
The determination of genetic background in metabolic syndrome (MetS) represents one of the necessary steps to prevent the disorder, thus reducing the cost of medical treatments and helping to design targeted therapy. The study explores the association between individual alleles of the LRP1 gene and the diagnosis of MetS to find correlation between the low-density lipoprotein receptor-related (LRP1) gene polymorphism and each individual anthropometric and biochemical parameter. The study included 93 males and females, aged from 19 to 65, divided into two groups...
June 30, 2017: Balkan Journal of Medical Genetics: BJMG
https://www.readbyqxmd.com/read/28919387/health-related-quality-of-life-in-adolescents-with-epilepsy-in-montenegro
#10
Nelica Ivanović Radović, Ksenija Božić, Aleksandra Plećaš Đurić, Sanja Vodopić, Ljiljana Radulović, Slavica Vujisić
OBJECTIVE: The objective of this study was to establish potential risk factors for poor health-related quality of life among adolescents with epilepsy in Montenegro. MATERIAL AND METHODS: A sample of 104 adolescents with epilepsy (age: 11-19years) at a tertiary referral center in Podgorica, Montenegro, completed the validated Serbian version of the QOLIE-AD-48 questionnaire. They were divided into two groups: a group with active epilepsy (60 adolescents) and a group with inactive epilepsy (44 adolescents)...
September 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28913333/utilization-of-parenteral-morphine-by-application-of-atc-ddd-methodology-retrospective-study-in-the-referral-teaching-hospital
#11
Viktorija Dragojevic-Simic, Nemanja Rancic, Dusica Stamenkovic, Radoje Simic
BACKGROUND: Few studies analyzed the pattern of opioid analgesic utilization in hospital settings. The aim of this study was to determine the consumption pattern of parenteral morphine in patients hospitalized in the Serbian referral teaching hospital and to correlate it with utilization at the national and international level. METHODS: In retrospective study, the required data were extracted from medical records of surgical patients who received parenteral morphine in the 5-year period, from 2011 to 2015...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28906511/association-of-cytokine-gene-polymorphism-with-peri-implantitis-risk
#12
Aleksandra Petkovic-Curcin, Katarina Zeljic, Bojana Cikota-Aleksic, Dragana Dakovic, Zoran Tatic, Zvonko Magic
PURPOSE: To investigate whether polymorphisms of cluster of differentiation 14 (CD14), tumor necrosis factor alpha (TNFα), interleukin (IL)6, IL10, and IL1ra genes are associated with the risk of peri-implantitis susceptibility in patients with dental implants in the Serbian population. MATERIALS AND METHODS: Isolated DNA from the blood was used for IL10-1082, TNFα-308, IL6-174, CD14-159, and interleukin 1 receptor antagonist (IL1ra) genotyping using polymerase chain reaction (PCR)-based methodology...
September 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28903432/genetic-variation-and-forensic-characteristic-analysis-of-25-strs-of-a-novel-fluorescence-co-amplification-system-in-chinese-southern-shaanxi-han-population
#13
Yao-Shun Liu, Jian-Gang Chen, Ting Mei, Yu-Xin Guo, Hao-Tian Meng, Jian-Fei Li, Yuan-Yuan Wei, Xiao-Ye Jin, Bo-Feng Zhu, Li-Ping Zhang
We analyzed the genetic polymorphisms of 15 autosomal and 10 Y-chromosomal STR loci in 214 individuals of Han population from Southern Shaanxi of China and studied the genetic relationships between Southern Shaanxi Han and other populations. We observed a total of 150 alleles at 15 autosomal STR loci with the corresponding allelic frequencies ranging from 0.0023 to 0.5210, and the combined power of discrimination and exclusion for the 15 autosomal STR loci were 0.99999999999999998866 and 0.999998491, respectively...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28902528/serbian-medical-students-fertility-awareness-and-attitudes-towards-future-parenthood
#14
Isidora Vujčić, Tijana Radičević, Eleonora Dubljanin, Nataša Maksimović, Sandra Grujičić
OBJECTIVES: Medical students represent a group particularly at risk of involuntary childlessness due to their highly demanding careers and university curriculum. The aim of this study was to investigate Serbian medical students' attitudes towards future parenthood and their awareness of fertility issues. METHODS: A cross-sectional study was conducted among fourth year students at the Faculty of Medicine, University of Belgrade, Serbia, between 12 and 16 December 2016...
September 13, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28872706/candida-bloodstream-infections-in-serbia-first-multi-center-report-of-a-national-prospective-observational-survey-in-intensive-care-units
#15
Valentina Arsić Arsenijević, Suzana Otašević, Dragana Janić, Predrag Minić, Jovan Matijašević, Deana Medić, Ivanka Savić, Snežana Delić, Suzana Laban Nestorović, Zorica Vasiljević, Mirjana Hadnadjev
Candida bloodstream infections (BSI) are a significant cause of mortality in intensive care units (ICU), hereof the prospective twelve-months (2014-2015) hospital and laboratory-based survey was performed at the Serbian National Reference Medical Mycology Laboratory (NRMML). Candida identification was done by a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and a susceptibility test, according to the Clinical and Laboratory Standards Institute methodology. Among 9 centers (265 beds; 10...
September 5, 2017: Mycoses
https://www.readbyqxmd.com/read/28871926/translation-and-validation-of-the-serbian-version-of-the-skindex-29-instrument-for-measuring-impact-of-skin-disease-on-quality-of-life
#16
Jelena D Milutinović, Nebojša Krstić, Slobodan M Janković
The Skindex-29 instrument, which is intended for measuring the influence of skin diseases on quality of life, was developed and validated in several languages. However, a Serbian translation of the instrument is not available. The aim of this study was to translate the Skindex-29 from English to Serbian, to make necessary cultural adaptations, and to test its psychometric properties in a sample of outpatients with various skin diseases. The Skindex-29 was translated and adapted according to internationally accepted guidelines and then tested on a sample of Serbian outpatients with various skin diseases...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28868569/genetic-analysis-of-12-x-str-loci-in-the-serbian-population-from-vojvodina-province
#17
Igor Veselinović, Dušan Vapa, Mihajla Djan, Nevena Veličković, Tanja Veljović, Galina Petrić
The analysis of 12 X-STR loci included in the Investigator® Argus X-12 kit was performed on a sample of 325 unrelated persons from Vojvodina Province, Republic of Serbia. No significant differences were observed in the allele frequencies in males and females. Heterozygosity values among the studied loci ranged from 67.62 to 94.28%. All loci in female individuals were consistent with the Hardy-Weinberg equilibrium test. The combined power of discrimination values in male and female individuals was 0.9999999994 and 0...
September 3, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28867403/optimization-of-the-monitoring-of-landfill-gas-and-leachate-in-closed-methanogenic-landfills
#18
Dejan Jovanov, Bogdana Vujić, Goran Vujić
Monitoring of the gas and leachate parameters in a closed landfill is a long-term activity defined by national legislative worldwide. Serbian Waste Disposal Law defines the monitoring of a landfill at least 30 years after its closing, but the definition of the monitoring extent (number and type of parameters) is incomplete. In order to define and clear all the uncertainties, this research focuses on process of monitoring optimization, using the closed landfill in Zrenjanin, Serbia, as the experimental model...
August 31, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28836031/a-field-screening-test-for-the-assessment-of-concentrations-and-mobility-of-potentially-toxic-elements-in-soils-a-case-study-on-urban-soils-from-rome-and-novi-sad
#19
Maria Rita Montereali, Valentina Pinto, Francesca Schiavella, Giovanna Armiento, Massimo Angelone, Cinzia Crovato, Maja Manojlović, Ranko Čabilovski, Carlo Cremisini
The increasing demand for environmental pollution control results in the development and use of new procedures for the determination of dangerous chemicals. Simple screening methods, which can be used directly in the field for a preliminary assessment of soil contamination, seem to be extremely advantageous. In our laboratory, we developed and optimized a rapid test for a preliminary evaluation of both the concentration and the mobility of some potentially toxic metals in soils. This screening test consists of a single extraction of the soil sample with a buffer solution, followed by the titration of the extracted solution with dithizone to determine the contents of bi-valent heavy metals (such as Pb, Cu, Zn, and Cd)...
August 23, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28815638/new-insights-into-the-origin-and-the-genetic-status-of-the-balkan-donkey-from-serbia
#20
L J Stanisic, J M Aleksic, V Dimitrijevic, P Simeunovic, U Glavinic, J Stevanovic, Z Stanimirovic
The Balkan donkey (Equus asinus L.) is commonly regarded as a large-sized, unselected, unstructured and traditionally managed donkey breed. We assessed the current genetic status of the three largest E. asinus populations in the central Balkans (Serbia) by analysing the variability of nuclear microsatellites and the mitochondrial (mtDNA) control region of 77 and 49 individuals respectively. We further analysed our mtDNA dataset along with 209 published mtDNA sequences of ancient and modern individuals from 19 European and African populations to provide new insights into the origin and the history of the Balkan donkey...
October 2017: Animal Genetics
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