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https://www.readbyqxmd.com/read/28079240/new-index-for-the-diagnosis-of-liver-fibrosis-in-schistosomiasis-mansoni
#1
Ana Virgínia Matos Sá Barreto, Vinícius Martins Alecrim, Tibério Batista de Medeiros, Ana Lúcia Coutinho Domingues, Edmundo Pessoa Lopes, João Roberto Maciel Martins, Helena Bonciani Nader, George Tadeu Nunes Diniz, Silvia Maria Lucena Montenegro, Clarice Neuenschwander Lins de Morais
BACKGROUND: - Periportal fibrosis is the major pathological consequence of the Schistosoma mansoni infection. OBJECTIVE: - To evaluate the accuracy of serum markers and to construct an index to assess fibrosis. METHODS: - Patients (n=116) with schistosomiasis were evaluated by ultrasound scan and measurements of serum levels of aminotransferases, γ-glutamyl transferase, alkaline phosphatase, hyaluronic acid, cytokines and platelets. Ultrasound images were used to evaluate the fibrosis using Niamey's classification and identified 19 patients without periportal fibrosis (patterns A and B), 48 with mild to moderate fibrosis (C and D) and 49 with advanced fibrosis (E and F)...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28074986/-recommendations-for-the-management-of-pancreatic-cancer-type-adenocarcinoma-a-consensus-statement-reached-during-the-2015-latin-american-symposium-on-gastroenterological-oncology
#2
Christian Caglevic, Jorge Gallardo, Marcela de la Torre, Mauricio Mahave, Bettina Müller, Sebastián Solé, Yuri Moscoso, Hernán De La Fuente, Juan Carlos Roa, Sebastián Hoefler, Jean M Butte, Pablo González M, Juan Manuel O'Connor, Javiera Torres, Verónica Pérez Encalada, Daniel Alarcón Cano, Luis Ubillos, Christian Rolfo, Alejo Lingua, Consuelo Díaz Romero, Alejandro Padilla Rosciano, Viviana Cuartero, Germán Calderillo Ruiz, Gilberto Schwartsmann, Xavier Kon Jara, Andrés Andrade G, Luis Mas López, Olga Barajas, Marcela Carballido, Hanns Lembach, Lena Morillas G, Enrique Roca, José Lobatón, Paola Montenegro B, Andrés Yepes, Hugo Marsiglia
Pancreatic cancer is a malignancy of great impact in developed countries and is having an increasing impact in Latin America. Incidence and mortality rates are similar for this cancer. This is an important reason to offer to the patients the best treatments available. During the Latin American Symposium of Gastroenterology Oncology (SLAGO) held in Viña del Mar, Chile, in April 2015, a multidisciplinary group of specialists in the field met to discuss about this disease. The main conclusions of this meeting, where practitioners from most of Latin American countries participated, are listed in this consensus that seek to serve as a guide for better decision making for patients with pancreatic cancer in Latin America...
October 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28069315/long-term-non-isothermal-reactive-transport-model-of-compacted-bentonite-concrete-and-corrosion-products-in-a-hlw-repository-in-clay
#3
Alba Mon, Javier Samper, Luis Montenegro, Acacia Naves, Jesús Fernández
Radioactive waste disposal in deep geological repositories envisages engineered barriers such as carbon-steel canisters, compacted bentonite and concrete liners. The stability and performance of the bentonite barrier could be affected by the corrosion products at the canister-bentonite interface and the hyper-alkaline conditions caused by the degradation of concrete at the bentonite-concrete interface. Additionally, the host clay formation could also be affected by the hyper-alkaline plume at the concrete-clay interface...
December 24, 2016: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28050539/comparative-analysis-of-pain-in-patients-who-underwent-total-knee-replacement-regarding-the-tourniquet-pressure
#4
Marcos George de Souza Leão, Gladys Pedrosa Martins Neta, Lucas Inoue Coutinho, Thiago Montenegro da Silva, Yacov Machado Costa Ferreira, Waryla Raissa Vasconcelos Dias
OBJECTIVES: To evaluate through the visual analog scale (VAS) the pain in patients undergoing total knee replacement (TKR) with different pressures of the pneumatic tourniquet. METHODS: An observational, randomized, descriptive study on an analytical basis, with 60 patients who underwent TKR, divided into two groups, which were matched: a group where TKR was performed with tourniquet pressures of 350 mmHg (standard) and the other with systolic blood pressure plus 100 mmHg (P + 100)...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28048665/su-f-t-243-major-risks-in-radiotherapy-a-review-based-on-risk-analysis-literature
#5
J López-Tarjuelo, A Bouché-Babiloni, V Morillo-Macías, M Guasp-Tortajada, N Iglesias-Montenegro, P Monasor-Denia, C Ferrer-Albiach
PURPOSE: We present a literature review of risk analyses in radiotherapy to highlight the most reported risks and facilitate the spread of this valuable information so that professionals can be aware of these major threats before performing their own studies. METHODS: We considered studies with at least an estimation of the probability of occurrence of an adverse event (O) and its associated severity (S). They cover external beam radiotherapy, brachytherapy, intraoperative radiotherapy, and stereotactic techniques...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045166/carborane-stilbene-dyads-the-influence-of-substituents-and-cluster-isomers-on-photoluminescence-properties
#6
A Ferrer-Ugalde, J Cabrera-González, E J Juárez-Pérez, F Teixidor, E Pérez-Inestrosa, J M Montenegro, R Sillanpää, M Haukka, R Núñez
Two novel styrene-containing meta-carborane derivatives substituted at the second carbon cluster atom (Cc) with either a methyl (Me) or a phenyl (Ph) group are introduced herein along with a new set of stilbene-containing ortho- (o-) and meta- (m-) carborane dyads. The latter set of compounds have been prepared from styrene-containing carborane derivatives via a Heck coupling reaction. High regioselectivity has been achieved for these compounds by using a combination of palladium complexes [Pd2(dba)3]/[Pd(t-Bu3P)2] as a catalytic system, yielding exclusively E isomers...
January 3, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28040660/quality-of-life-and-swallowing-with-standard-chemoradiotherapy-versus-accelerated-radiotherapy-and-panitumumab-in-locoregionally-advanced-carcinoma-of-the-head-and-neck-a-phase-iii-randomised-trial-from-the-canadian-cancer-trials-group-hn-6
#7
Jolie Ringash, John N Waldron, Lillian L Siu, Rosemary Martino, Eric Winquist, Jim R Wright, Abdenour Nabid, John H Hay, Alex Hammond, Khalil Sultanem, Sebastien Hotte, Carson Leong, Ali Abdel Halim El-Gayed, Farah Naz, Kevin Ramchandar, Timothy E Owen, Alexander Montenegro, Brian O'Sullivan, Bingshu E Chen, Wendy R Parulekar
AIM: To compare quality of life (QOL) between standard (SFX) chemoradiotherapy (arm A) and altered fractionation radiotherapy (AFX) with panitumumab (PMab; arm B). METHODS: Patients with T any N + M0 or T3-4N0M0 squamous cell head-neck carcinoma were randomised to SFX (70 Gy/35/7 wks) plus cisplatin (100 mg/m(2) IV × 3) versus AFX (70 Gy/35/6 wks) plus PMab (9 mg/kg IV × 3). QOL was collected at baseline, end of radiation therapy (RT) and 2, 4, 6, 12, 24 and 36 months post-RT using the Functional Assessment of Cancer Therapy Head and Neck (FACT-H&N), MD Anderson Dysphagia Index (MDADI) and SWAL-QOL...
December 29, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/28039781/subjective-memory-complaints-in-healthy-older-adults-fewer-complaints-associated-with-depression-and-perceived-health-more-complaints-also-associated-with-lower-memory-performance
#8
Pedro Montejo Carrasco, Mercedes Montenegro-Peña, Ramón López-Higes, Eduardo Estrada, David Prada Crespo, Christian Montejo Rubio, David García Azorín
OBJECTIVES: (i) To analyze if general cognitive performance, perceived health and depression are predictors of Subjective Memory Complaints (SMC) contrasting their effect sizes; (ii) to analyze the relationship between SMC and objective memory by comparing a test that measures memory in daily life and a classical test of associated pairs; (iii) to examine if different subgroups, formed according to the MFE score, might have different behaviors regarding the studied variables. METHODS: Sample: 3921 community-dwelling people (mean age 70...
December 16, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28033660/wide-spectrum-of-nr5a1-related-phenotypes-in-46-xy-and-46-xx-individuals
#9
REVIEW
Sorahia Domenice, Aline Zamboni Machado, Frederico Moraes Ferreira, Bruno Ferraz-de-Souza, Antonio Marcondes Lerario, Lin Lin, Mirian Yumie Nishi, Nathalia Lisboa Gomes, Thatiana Evelin da Silva, Rosana Barbosa Silva, Rafaela Vieira Correa, Luciana Ribeiro Montenegro, Amanda Narciso, Elaine Maria Frade Costa, John C Achermann, Berenice Bilharinho Mendonca
Steroidogenic factor 1 (NR5A1, SF-1, Ad4BP) is a transcriptional regulator of genes involved in adrenal and gonadal development and function. Mutations in NR5A1 have been among the most frequently identified genetic causes of gonadal development disorders and are associated with a wide phenotypic spectrum. In 46,XY individuals, NR5A1-related phenotypes may range from disorders of sex development (DSD) to oligo/azoospermia, and in 46,XX individuals, from 46,XX ovotesticular and testicular DSD to primary ovarian insufficiency (POI)...
December 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://www.readbyqxmd.com/read/28031423/neurologic-injury-and-cerebral-blood-flow-in-single-ventricles-throughout-staged-surgical-reconstruction
#10
Mark A Fogel, Christine J Li, Okan U Elci, Tom Pawlowski, Peter J Schwab, Felice B Wilson, Susan C Nicolson, Lisa M Montenegro, Laura Diaz, Thomas L Spray, J William Gaynor, Stephanie Fuller, Christopher E Mascio, Marc S Keller, Matthew A Harris, Kevin K Whitehead, James Bethel, Arastoo Vossough, Daniel J Licht
BACKGROUND: -Single ventricle patients experience a high rate of brain injury and adverse neurodevelopmental outcome, however, the incidence of brain abnormalities throughout surgical reconstruction and its relationship with cerebral blood flow, oxygen delivery and carbon dioxide reactivity remains unknown. METHODS: -Single ventricle patients were studied with MRI scans immediately prior to bidirectional Glenn (pre-BDG), prior to Fontan and then 3-9 months after Fontan reconstruction...
December 28, 2016: Circulation
https://www.readbyqxmd.com/read/28027870/novel-triclabendazole-prodrug-a-highly-water-soluble-alternative-for-the-treatment-of-fasciolosis
#11
Miguel Flores-Ramos, Froylán Ibarra-Velarde, Helgi Jung-Cook, Alicia Hernández-Campos, Yolanda Vera-Montenegro, Rafael Castillo
In this work we present the synthesis, aqueous solubility and stability, hydrolysis by alkaline phosphatase, and in vivo fasciolicidal activity in sheep of a highly water soluble phosphate salt prodrug of triclabendazole (MFR-5). The aqueous solubility of MFR-5 at pH 7 was 88,000-fold that of triclabendazole. MFR-5 showed excellent aqueous stability (>95% after 26h) at pH 7, making it ideal for developing pharmaceutical compositions in the form of solutions that can easily be hydrolyzed by the enzyme alkaline phosphatase (t=13...
December 2, 2016: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28027568/perineal-massage-improves-the-dyspareunia-caused-by-tenderness-of-the-pelvic-floor-muscles
#12
Ana Paula Moreira da Silva, Mary Lourdes Montenegro, Maria Beatriz Ferreira Gurian, Andreia Moreira de Souza Mitidieri, Lucia Alves da Silva Lara, Omero Benedicto Poli-Neto, Julio Cesar Rosa E Silva
Aim To evaluate the long-term effectiveness of perineal Thiele massage in the treatment of women with dyspareunia caused by tenderness of the pelvic floor muscles. Methods A total of 18 women with diagnoses of dyspareunia caused by tenderness of the pelvic floor muscles were included in the study. The women were divided in two groups: the dyspareunia (D) group - 8 women with dyspareunia caused by tenderness of the pelvic floor muscles; and the chronic pelvic pain group (CPP) group - 10 women with dyspareunia caused by tenderness of the pelvic floor muscles associated with CPP...
December 27, 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28003553/economics-of-home-monitoring-for-apnea-in-late-preterm-infants
#13
Brian L Montenegro, Michael Amberson, Lauren Veit, Christina Freiberger, Dmitry Dukhovny, Lawrence M Rhein
BACKGROUND: Apnea of prematurity affects a small proportion but large absolute number of late preterm infants, with out-patient management variably utilized despite relative clinical equipoise and potential for improved cost-effectiveness. METHODS: Over a 5-y period, from 2009 to 2013, infants born at ≥34 weeks gestational age at a level IIIB academic center in Boston, Massachusetts, with discharge-delaying apnea, bradycardia, and desaturation (ABD) events were identified...
January 2017: Respiratory Care
https://www.readbyqxmd.com/read/27988611/study-on-tychini-of-balkan-peninsula-coleoptera-staphylinidae-pselaphinae
#14
Giorgio Sabella, Adam Šíma
Tychus albanicus sp. n. from southern Albania is described and illustrated, and placed in the Tychus monilicornis group. The following new records of Tychus species are given for Balkan Peninsula: Tychus corsicus spissatus Rey, 1888 for Croatia; Tychus cordiger Besuchet, 1969, Tychus monilicornis Reitter, 1880, and Tychus niger Paykull, 1800 for Montenegro, and Tychus caudatus Reitter, 1884 for Albany. Tychus sbordonii Meggiolaro, 1967 is trasferred from the Tychus dalmatinus group to the Tychus monilicornis group...
December 1, 2016: Zootaxa
https://www.readbyqxmd.com/read/27988546/studies-on-i-adriaphaenops-i-noesske-with-the-description-of-five-new-species-from-the-dinarides-coleoptera-carabidae-trechini
#15
Roman Lohaj, Ján Lakota, Eric Quéinnec, Dragan Pavićević, Dávid Čeplík
The species belonging to the trechine genus Adriaphaenops Noesske, 1928 are studied. As a result, seven currently known and five newly described species are recognized. Morphological characters of the habitus (especially the shape of head and pronotum) as well as male genitalia are widely used to delimit the species. The following new species are described: A. albanicus sp. nov. (Albania, Shkodër, Boga, Thatë Mts.), A. jasminkoi sp. nov. (Bosnia & Hercegovina, Nevesinje, Novakova pećina cave), A. mlejneki sp...
December 12, 2016: Zootaxa
https://www.readbyqxmd.com/read/27983788/data-streaming-for-metabolomics-accelerating-data-processing-and-analysis-from-days-to-minutes
#16
J Rafael Montenegro-Burke, Aries E Aisporna, H Paul Benton, Duane Rinehart, Mingliang Fang, Tao Huan, Benedikt Warth, Erica M Forsberg, Brian T Abe, Julijana Ivanisevic, Luc Teyton, Luke L Lairson, Gary Siuzdak
The speed and throughput of analytical platforms has been a driving force in recent years in the "omics" technologies and while great strides have been accomplished in both chromatography and mass spectrometry, data analysis times have not benefited at the same pace. Even though personal computers have become more powerful, data transfer times still represent a bottleneck in data processing due to the increasingly complex data files and studies with a greater number of samples. To meet the demand of analyzing hundreds to thousands of samples within a given experiment, we have developed a data streaming platform, XCMS Stream, which capitalizes on the acquisition time to compress and stream recently acquired data files to data processing servers, mimicking just-in-time production strategies from the manufacturing industry...
December 16, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27982343/intraoperative-analysis-of-flow-dynamics-in-arteriovenous-composite-y-grafts
#17
Heraldo Guedis Lobo, José Glauco Lobo, Matheus Duarte Pimentel, Bruno Gadelha Bezerra Silva, Camylla Santos de Souza, Marília Leitão Montenegro, Maria Cláudia de Azevedo Leitão, Francisco Vagnaldo Fechine Jamacuru
Objective: Composite graft of left internal thoracic artery and great saphenous vein in revascularization of the left coronary system is a technique well described in literature. The aim of this study is to analyze blood flow dynamics in this configuration of composite graft especially in what concerns left internal thoracic artery's adaptability and influence of great saphenous vein segment on left internal thoracic artery's flow. Methods: Revascularization of left coronary system with composite graft, with left internal thoracic artery revascularizing the anterior interventricular artery and a great saphenous vein segment, anastomosed to the left internal thoracic artery, revascularizing another branch of the left coronary system, was performed in 23 patients...
September 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27982325/the-deceptive-concept-of-hypoparathyroidism-and-recurrence-after-parathyroidectomy-in-dialysis-patients-are-we-offering-a-procrustean-bed-to-some-patients
#18
Fabio Luiz DE Menezes Montenegro, Marilia D'Elboux Guimaraes Brescia, Climério Pereira Nascimento, Ledo Mazzei Massoni, Sérgio Samir Arap, Stênio Roberto Castro Lima Santos, Patrícia Taschner Goldenstein, Rodrigo Oliveira Bueno, Melani Ribeiro Custodio, Vanda Jorgetti, Rosa Maria Affonso Moyses
Objective: to analyze the frequency of hypoparathyroidism and of its recurrence after parathyroidectomy in dialysis patients according to different existing classifications. Methods: we conducted a retrospective study of 107 consecutive dialysis patients undergoing total parathyroidectomy with immediate autograft in a tertiary hospital from 2006 to 2010. We studied the changes in PTH levels in the postoperative period over time. Were grouped patients according to different PTH levels targets recommended according to the dosage method and by the American and Japanese Nephrology Societies, and by an International Experts Consortium...
September 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/27972235/the-mosaic-study-regional-variation-in-treatment-patterns-associated-with-progression-from-initial-insulin-regimen
#19
J Bae, B H Curtis, J R Rogers, B Linetzky, A K Ali, M Tsoukas, S Beshyah, I Matsuba, M Araz, R Magalhaes Montenegro, S Kim
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27942680/microscale-flow-dynamics-of-ribbons-and-sheets
#20
Thomas D Montenegro-Johnson, Lyndon Koens, Eric Lauga
Numerical study of the hydrodynamics of thin sheets and ribbons presents difficulties associated with resolving multiple length scales. To circumvent these difficulties, asymptotic methods have been developed to describe the dynamics of slender fibres and ribbons. However, such theories entail restrictions on the shapes that can be studied, and often break down in regions where standard boundary element methods are still impractical. In this paper we develop a regularised stokeslet method for ribbons and sheets in order to bridge the gap between asymptotic and boundary element methods...
December 12, 2016: Soft Matter
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