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https://www.readbyqxmd.com/read/27921111/rapid-detection-of-hendra-virus-antibodies-an-integrated-device-with-nanoparticle-assay-and-chaotic-micromixing
#1
K Petkovic, G Metcalfe, H Chen, Y Gao, M Best, D Lester, Y Zhu
Current diagnosis of infectious diseases such as Hendra virus (HeV) relies mostly on laboratory-based tests. There is an urgent demand for rapid diagnosis technology to detect and identify these diseases in humans and animals so that disease spread can be controlled. In this study, an integrated lab-on-a-chip device using a magnetic nanoparticle immunoassay is developed. The key features of the device are the chaotic fluid mixing, achieved by magnetically driven motion of nanoparticles with the optimal mixing protocol developed using chaotic transport theory, and the automatic liquid handling system for loading reagents and samples...
December 6, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27920424/ultrastructural-characterization-of-the-lower-motor-system-in-a-mouse-model-of-krabbe-disease
#2
Valentina Cappello, Laura Marchetti, Paola Parlanti, Silvia Landi, Ilaria Tonazzini, Marco Cecchini, Vincenzo Piazza, Mauro Gemmi
Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by widespread accumulation of the cytotoxic galactosyl-sphingosine in neuronal, myelinating and endothelial cells. Despite the wide use of Twitcher mice as experimental model for KD, the ultrastructure of this model is partial and mainly addressing peripheral nerves. More details are requested to elucidate the basis of the motor defects, which are the first to appear during KD onset. Here we use transmission electron microscopy (TEM) to focus on the alterations produced by KD in the lower motor system at postnatal day 15 (P15), a nearly asymptomatic stage, and in the juvenile P30 mouse...
December 2016: Scientific Reports
https://www.readbyqxmd.com/read/27920374/urban-driven-phenotypic-changes-empirical-observations-and-theoretical-implications-for-eco-evolutionary-feedback
#3
REVIEW
Marina Alberti, John Marzluff, Victoria M Hunt
Emerging evidence that cities drive micro-evolution raises the question of whether rapid urbanization of Earth might impact ecosystems by causing systemic changes in functional traits that regulate urban ecosystems' productivity and stability. Intraspecific trait variation-variation in organisms' morphological, physiological or behavioural characteristics stemming from genetic variability and phenotypic plasticity-has significant implications for ecological functions such as nutrient cycling and primary productivity...
January 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/27920082/doctors-perspectives-on-psa-testing-illuminate-established-differences-in-prostate-cancer-screening-rates-between-australia-and-the-uk-a-qualitative-study
#4
Kristen Pickles, Stacy M Carter, Lucie Rychetnik, Vikki A Entwistle
OBJECTIVES: To examine how general practitioners (GPs) in the UK and GPs in Australia explain their prostate-specific antigen (PSA) testing practices and to illuminate how these explanations are similar and how they are different. DESIGN: A grounded theory study. SETTING: Primary care practices in Australia and the UK. PARTICIPANTS: 69 GPs in Australia (n=40) and the UK (n=29). We included GPs of varying ages, sex, clinical experience and patient populations...
December 5, 2016: BMJ Open
https://www.readbyqxmd.com/read/27919383/social-capital-and-transaction-cost-on-co-creating-it-value-towards-inter-organizational-emr-exchange
#5
Hsin Hsin Chang, Chung-Jye Hung, Ching Ying Huang, Kit Hong Wong, Yi Ju Tsai
This study adopts social capital theory and transaction cost theory to explore the feasibility of an inter-organizational cross-hospital electronic medical records (EMR) exchange system, and the factors that affect its adoption. The concept of value co-creation is also used to assess such a system, and its influence on the performance of participating medical institutes. This research collected 330 valid paper-based questionnaires from the medical staff of various institutes. The results showed that social interaction ties and shared vision positively affected medical institutes' willingness to adopt the EMR exchange system, while asset specificity and uncertainty increased the related transaction costs...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27918896/the-physical-mechanism-of-inhomogeneous-magnetization-transfer-mri
#6
Alan P Manning, Kimberley L Chang, Alex L MacKay, Carl A Michal
Inhomogeneous MT (ihMT) is a new magnetic resonance imaging technique that shows promise for myelin selectivity. Materials with a high proportion of lipids, such as white matter tissue, show a reduced intensity in magnetic resonance images acquired with selective prepulses at positive and negative offsets simultaneously compared to images with a single positive or negative offset prepulse of the same power. This effect was initially explained on the basis of hole-burning in inhomogeneously broadened lines of the lipid proton spin system...
November 24, 2016: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/27918466/evaluating-a-website-to-teach-children-safety-with-dogs-a-randomized-controlled-trial
#7
David C Schwebel, Peng Li, Leslie A McClure, Joan Severson
Dog bites represent a significant threat to child health. Theory-driven interventions scalable for broad dissemination are sparse. A website was developed to teach children dog safety via increased knowledge, improved cognitive skills in relevant domains, and increased perception of vulnerability to bites. A randomized controlled trial was conducted with 69 children aged 4-5 randomly assigned to use the dog safety website or a control transportation safety website for ~3 weeks. Assessment of dog safety knowledge and behavior plus skill in three relevant cognitive constructs (impulse control, noticing details, and perspective-taking) was conducted both at baseline and following website use...
December 2, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27918030/solvation-behavior-of-carbonate-based-electrolytes-in-sodium-ion-batteries
#8
Arthur V Cresce, Selena M Russell, Oleg Borodin, Joshua A Allen, Marshall A Schroeder, Michael Dai, Jing Peng, Mallory P Gobet, Steven G Greenbaum, Reginald E Rogers, Kang Xu
Sodium ion batteries are on the cusp of being a commercially available technology. Compared to lithium ion batteries, sodium ion batteries can potentially offer an attractive dollar-per-kilowatt-hour value, though at the penalty of reduced energy density. As a materials system, sodium ion batteries present a unique opportunity to apply lessons learned in the study of electrolytes for lithium ion batteries; specifically, the behavior of the sodium ion in an organic carbonate solution and the relationship of ion solvation with electrode surface passivation...
December 5, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27918022/a-systematic-study-of-25-mg-nmr-in-paramagnetic-transition-metal-oxides-applications-to-mg-ion-battery-materials
#9
Jeongjae Lee, Ieuan D Seymour, Andrew J Pell, Siân E Dutton, Clare P Grey
Rechargeable battery systems based on Mg-ion chemistries are generating significant interest as potential alternatives to Li-ion batteries. Despite the wealth of local structural information that could potentially be gained from Nuclear Magnetic Resonance (NMR) experiments of Mg-ion battery materials, systematic (25)Mg solid-state NMR studies have been scarce due to the low natural abundance, low gyromagnetic ratio, and significant quadrupole moment of (25)Mg (I = 5/2). This work reports a combined experimental (25)Mg NMR and first principles density functional theory (DFT) study of paramagnetic Mg transition metal oxide systems Mg6MnO8 and MgCr2O4 that serve as model systems for Mg-ion battery cathode materials...
December 5, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27917748/making-brains-run-faster-are-they-becoming-smarter
#10
Anja Pahor, Norbert Jaušovec
A brief overview of structural and functional brain characteristics related to g is presented in the light of major neurobiological theories of intelligence: Neural Efficiency, P-FIT and Multiple-Demand system. These theories provide a framework to discuss the main objective of the paper: what is the relationship between individual alpha frequency (IAF) and g? Three studies were conducted in order to investigate this relationship: two correlational studies and a third study in which we experimentally induced changes in IAF by means of transcranial alternating current stimulation (tACS)...
December 5, 2016: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/27917739/do-cognitive-and-physical-functions-age-in-concert-from-age-70-to-76-evidence-from-the-lothian-birth-cohort-1936
#11
Stuart J Ritchie, Elliot M Tucker-Drob, John M Starr, Ian J Deary
The present study concerns the relation of mental and bodily characteristics to one another during ageing. The 'common cause' theory of ageing proposes that declines are shared across multiple, seemingly-disparate functions, including both physical and intellectual abilities. The concept of 'reserve' suggests that healthier cognitive (and perhaps bodily) functions from early in life are protective against the effects of senescence across multiple domains. In three waves of physical and cognitive testing data from the longitudinal Lothian Birth Cohort 1936 (n = 1,091 at age 70 years; n = 866 at 73; n = 697 at 76), we used multivariate growth curve modeling to test the 'common cause' and 'reserve' hypotheses...
December 5, 2016: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/27917626/association-of-new-putative-epitopes-of-myelin-proteolipid-protein-58-74-with-pathogenesis-of-multiple-sclerosis
#12
Zahra Zamanzadeh, Ghasem Ahangari, Mitra Ataei, Samie Pouragahi, Seyed Massood Nabavi, Mehdi Sadeghi, Mohammad Hossein Sanati
Multiple sclerosis (MS) is an autoimmune disease in which auto-reactive T cells react with self-antigens expressed in the central nervous system (CNS). The main cause of MS is unknown. Nonetheless, the most probable theory is based on molecular mimicry, which suggests that some infections can activate T cells against brain auto-antigens like myelin proteolipid protein (PLP) and initiate the disease cascade. This study is conducted to evaluate the activatory effects of PLP58-74 on T lymphocytes and humoral immunity...
October 2016: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/27917583/electronic-spectroscopy-of-methylcyanodiacetylene-ch3-c5-n
#13
Michał Turowski, Urszula Szczepaniak, Thomas Custer, Marcin Gronowski, Robert Kołos
The results of a study devoted to the electronic spectroscopy of gaseous, solid, and cryogenic matrix-isolated methylcyanodiacetylene (CH3 C5 N) are reported. UV absorption and optical phosphorescence spectra of the compound are described here for the first time, and the corresponding vibronic assignments are proposed. UV absorption, studied directly or through the excitation of phosphorescence, revealed the B˜  (1) E--X˜  (1) A1 system, very weak A˜  (1) A2 -X˜  (1) A1 bands, and a strong, broad absorption feature, tentatively identified as D˜  (1) E-X˜  (1) A1 ...
December 5, 2016: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/27917532/do-women-have-a-choice-care-providers-and-decision-makers-perspectives-on-barriers-to-access-of-health-services-for-birth-after-a-previous-cesarean
#14
Sarah Munro, Jude Kornelsen, Kitty Corbett, Elizabeth Wilcox, Nick Bansback, Patricia Janssen
BACKGROUND: Repeat cesarean delivery is the single largest contributor to the escalating cesarean rate worldwide. Approximately 80 percent of women with a past cesarean are candidates for vaginal birth after a cesarean (VBAC), but in Canada less than one-third plan VBAC. Emerging evidence suggests that these trends may be due in part to nonclinical factors, including care provider practice patterns and delays in access to surgical and anesthesia services. This study sought to explore maternity care providers' and decision makers' attitudes toward and experiences with providing and planning services for women with a previous cesarean...
December 5, 2016: Birth
https://www.readbyqxmd.com/read/27917350/completeness-and-regularity-of-generalized-fuzzy-graphs
#15
Sovan Samanta, Biswajit Sarkar, Dongmin Shin, Madhumangal Pal
Fuzzy graphs are the backbone of many real systems like networks, image, scheduling, etc. But, due to some restriction on edges, fuzzy graphs are limited to represent for some systems. Generalized fuzzy graphs are appropriate to avoid such restrictions. In this study generalized fuzzy graphs are introduced. In this study, matrix representation of generalized fuzzy graphs is described. Completeness and regularity are two important parameters of graph theory. Here, regular and complete generalized fuzzy graphs are introduced...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917306/education-and-training-of-emergency-medical-teams-recommendations-for-a-global-operational-learning-framework
#16
Nieves Amat Camacho, Amy Hughes, Frederick M Burkle, Pier Luigi Ingrassia, Luca Ragazzoni, Anthony Redmond, Ian Norton, Johan von Schreeb
An increasing number of international emergency medical teams are deployed to assist disaster-affected populations worldwide. Since Haiti earthquake those teams have been criticised for ill adapted care, lack of preparedness in addition to not coordinating with the affected country healthcare system. The Emergency Medical Teams (EMTs) initiative, as part of the Word Health Organization's Global Health Emergency Workforce program, aims to address these shortcomings by improved EMT coordination, and mechanisms to ensure quality and accountability of national and international EMTs...
October 21, 2016: PLoS Currents
https://www.readbyqxmd.com/read/27917256/toward-accurate-adsorption-energetics-on-clay-surfaces
#17
Andrea Zen, Loïc M Roch, Stephen J Cox, Xiao Liang Hu, Sandro Sorella, Dario Alfè, Angelos Michaelides
Clay minerals are ubiquitous in nature, and the manner in which they interact with their surroundings has important industrial and environmental implications. Consequently, a molecular-level understanding of the adsorption of molecules on clay surfaces is crucial. In this regard computer simulations play an important role, yet the accuracy of widely used empirical force fields (FF) and density functional theory (DFT) exchange-correlation functionals is often unclear in adsorption systems dominated by weak interactions...
November 23, 2016: Journal of Physical Chemistry. C, Nanomaterials and Interfaces
https://www.readbyqxmd.com/read/27917255/can-ice-like-structures-form-on-non-ice-like-substrates-the-example-of-the-k-feldspar-microcline
#18
Philipp Pedevilla, Stephen J Cox, Ben Slater, Angelos Michaelides
Feldspar minerals are the most common rock formers in Earth's crust. As such they play an important role in subjects ranging from geology to climate science. An atomistic understanding of the feldspar structure and its interaction with water is therefore desirable, not least because feldspar has been shown to dominate ice nucleation by mineral dusts in Earth's atmosphere. The complexity of the ice/feldspar interface arising from the numerous chemical motifs expressed on the surface makes it a challenging system...
March 31, 2016: Journal of Physical Chemistry. C, Nanomaterials and Interfaces
https://www.readbyqxmd.com/read/27917103/motor-imagery-during-action-observation-a-brief-review-of-evidence-theory-and-future-research-opportunities
#19
REVIEW
Daniel L Eaves, Martin Riach, Paul S Holmes, David J Wright
Motor imagery (MI) and action observation (AO) have traditionally been viewed as two separate techniques, which can both be used alongside physical practice to enhance motor learning and rehabilitation. Their independent use has largely been shown to be effective, and there is clear evidence that the two processes can elicit similar activity in the motor system. Building on these well-established findings, research has now turned to investigate the effects of their combined use. In this article, we first review the available neurophysiological and behavioral evidence for the effects of combined action observation and motor imagery (AO+MI) on motor processes...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27915367/the-virtual-reality-head-mounted-display-oculus-rift-induces-motion-sickness-and-is-sexist-in-its-effects
#20
Justin Munafo, Meg Diedrick, Thomas A Stoffregen
Anecdotal reports suggest that motion sickness may occur among users of contemporary, consumer-oriented head-mounted display systems and that women may be at greater risk. We evaluated the nauseogenic properties of one such system, the Oculus Rift. The head-mounted unit included motion sensors that were sensitive to users' head movements, such that head movements could be used as control inputs to the device. In two experiments, seated participants played one of two virtual reality games for up to 15 min. In Experiment 1, 22% of participants reported motion sickness, and the difference in incidence between men and women was not significant...
December 3, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
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