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https://www.readbyqxmd.com/read/28730149/review-of-antibiotic-resistance-in-the-indian-ocean-commission-a-human-and-animal-health-issue
#1
REVIEW
Noellie Gay, Olivier Belmonte, Jean-Marc Collard, Mohamed Halifa, Mohammad Iqbal Issack, Saindou Mindjae, Philippe Palmyre, Abdul Aziz Ibrahim, Harena Rasamoelina, Loïc Flachet, Laurent Filleul, Eric Cardinale
Antimicrobial resistance (AMR) is a major threat to human, animal health, and environment worldwide. For human, transmission occurred through a variety of routes both in health-care settings and community. In animals, AMR was reported in livestock, pets, and wildlife; transmission of AMR can be zoonotic with the probably most important route being foodborne transmission. The Indian Ocean Commission (IOC), composed of Comoros, Madagascar, Mauritius, Reunion (France), and Seychelles recognized the surveillance of AMR in both animal and human as a main public health priority for the region...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28720919/delivering-tobacco-cessation-content-in-the-middle-east-through-interprofessional-learning
#2
Alla El-Awaisi, Ahmed Awaisu, Maguy Saffouh El Hajj, Bayan Alemrayat, Ghadir Al-Jayyousi, Norman Wong, Mohamud A Verjee
Objective. To explore the attitudes of pharmacy, pharmacy technician, medical, and public health students before and after an IPE activity that focused on smoking cessation in the Middle East. Methods. A pre-post intervention research design using the Readiness for Interprofessional Learning Scale (RIPLS) was used for this study. The tool contained 20 items, categorized under the following subscales: teamwork and collaboration, professional identity, and patient-centeredness. Results. A total of 47 out of 50 students from four different health disciplines in Qatar (medicine, pharmacy, pharmacy technician, and public health) who participated in the activity completed a pre- and post-intervention pre-validated questionnaire (94% response rate)...
June 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28706216/highly-efficient-multicolor-multifocus-microscopy-by-optimal-design-of-diffraction-binary-gratings
#3
Bassam Hajj, Laura Oudjedi, Jean-Bernard Fiche, Maxime Dahan, Marcelo Nollmann
Multifocus microscopy (MFM) allows sensitive and fast three-dimensional imaging. It relies on the efficient design of diffraction phase gratings yielding homogeneous intensities in desired diffraction orders. Such performances are however guaranteed only for a specific wavelength. Here, we discuss a novel approach for designing binary phase gratings with dual color properties and improved diffraction efficiency for MFM. We simulate binary diffraction gratings with tunable phase shifts to explore its best diffraction performances...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28694114/epigenetic-dysregulation-of-protocadherins-in-human-disease
#4
REVIEW
Nady El Hajj, Marcus Dittrich, Thomas Haaf
Protocadherins (Pcdhs) are a group of cell-cell adhesion molecules that are highly expressed in the nervous system and have a major function in dendrite development and neural circuit formation. However, the role protocadherins play in human health and disease remains unclear. Several recent studies have associated epigenetic dysregulation of protocadherins with possible implications for disease pathogenesis. In this review, we briefly recap the various epigenetic mechanisms regulating protocadherin genes, particularly the clustered Pcdhs...
July 7, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28680601/liver-hydatid-cyst-with-cutaneous-fistulization-to-the-right-breast-a-case-report-management-and-literature-review
#5
Mansour El Khoury, Antoine El Asmar, Wissam Dib, Elie Creidi, Madeleine Yehia, Imad Hajj
Echinococcus granulosus is the most common tapeworm causing hydatid disease in humans. Its least-encountered complication is cutaneous fistulization. Omentoplasty, cyst, and fistulous tract drainage revealed successful in the management of this complication. Such intervention can be an alternative when conservative management fails, and a minimally aggressive procedure is required.
July 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28678211/incidence-and-impact-of-stroke-during-hajj-results-of-2015-hajj-stroke-registry
#6
Mohammed A Almekhlafi, Maher A Alhazmi, Sarah S Alsulami, Soha A Almorsy
OBJECTIVE: To investigate the incidence of stroke among pilgrims and describe factors associated with presentation and management during Hajj. Physical stress, age and vascular risk factors render pilgrims at a high risk of stroke. METHODS: This is a prospective registry of all acute stroke patients admitted to 6 hospitals during the 2015 Hajj season from 9 September to 4 November. Participating hospitals were King Abdullah Medical City (KAMC), Al-Noor, King Abdulaziz hospital, King Faisal hospital, Hira, and Mena general hospitals; all in Makkah city...
July 2017: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/28668659/morbidity-and-mortality-amongst-indian-hajj-pilgrims-a-3-year-experience-of-indian-hajj-medical-mission-in-mass-gathering-medicine
#7
Inam D Khan, Shahbaz A Khan, Bushra Asima, Syed B Hussaini, M Zakiuddin, F A Faisal
The Hajj, a mass-gathering of over 3.5-million pilgrims, faces challenges to global health-security, housing, food, water, transportation, communication, sanitation, crowd-control and security. The Indian Medical Mission extended health-security to approximately 140,000 pilgrims, through outreach medical teams, primary-care clinics, tent-clinics, secondary-care hospitals and evacuation capabilities. Data on medical attendance, bed-occupancy, investigations, referrals, medication usage and deaths was compared...
June 28, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28668305/detrimental-role-of-lysyl-oxidase-in-cardiac-remodeling
#8
Elia C El Hajj, Milad C El Hajj, Van K Ninh, Jessica M Bradley, Mario A Claudino, Jason D Gardner
A key feature of heart failure is adverse extracellular matrix (ECM) remodeling, which is associated with increases in the collagen cross-linking enzyme, lysyl oxidase (LOX). In this study, we assess the progression of cardiovascular remodeling from the compensatory to decompensatory phase, with a focus on the change in LOX expression and activity as it relates to alterations in ECM composition and changes in cardiac function. Adult male Sprague-Dawley rats were studied after 4, 14, or 21weeks of aortocaval fistula-induced volume overload (VO)...
June 29, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28661823/stereotactic-body-radiation-vs-intensity-modulated-radiation-for-unresectable-pancreatic-cancer
#9
Joseph J Park, Carla Hajj, Marsha Reyngold, Weiji Shi, Zhigang Zhang, John J Cuaron, Christopher H Crane, Eileen M O'Reilly, Maeve A Lowery, Kenneth H Yu, Karyn A Goodman, Abraham J Wu
BACKGROUND: Stereotactic body radiation therapy (SBRT) is an emerging treatment option for unresectable pancreatic cancer, and is postulated to be more effective and less toxic than conventionally fractionated intensity modulated radiation therapy (IMRT). MATERIAL AND METHODS: We retrospectively reviewed unresectable stage I-III pancreatic adenocarcinoma treated from 2008 to 2016 at our institution with SBRT (five fractions, 30-33 Gy) or IMRT (25-28 fractions, 45-56 Gy with concurrent chemotherapy)...
June 29, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28660688/use-of-contrast-enhanced-ultrasound-for-confirmation-of-central-venous-catheter-placement-systematic-review-and-meta-analysis
#10
Ralph Bou Chebl, Shafeek Kiblawi, Christopher El Khuri, Nadine El Hajj, Rana Bachir, Roni Aoun, Gilbert Abou Dagher
OBJECTIVES: The purpose of this meta-analysis was to determine the sensitivity, specificity, and positive and negative predictive values of contrast-enhanced ultrasound (US) for confirming the tip location and placement of central venous catheters in adult patients. METHODS: A systematic review was performed using electronic databases, including MEDLINE, ClinicalTrials.gov, Cochrane, Embase, PubMed, and Scopus. Inclusion criteria were studies conducted on adult patients receiving an internal jugular or a subclavian central venous catheter in the emergency department or intensive care unit...
June 29, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28659007/pancarditis-an-unusual-complication-of-a-group-b-streptococcal-infection
#11
Elisa Larrieu-Ardilouze, Luc Christiaens, Nicolas Varroud-Vial, Coralie Madico, Jamil Hajj-Chahine, Michaela B Rehman
Pancarditis is a rare condition with a poor prognosis combining endocarditis, myocarditis with abscess formation, and purulent pericarditis. Diagnosis is often delayed and the clinical signs are predominantly those of the embolic complications. Literature is scarce. We present a unique and rare case of pancarditis, complicating a Streptococcal B infection in an immunocompetent, healthy, 54 year-old woman. The evolution was favourable under medical therapy alone and thanks to multimodality cardiac imaging diagnosis and follow-up...
June 28, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28658526/reverse-pharmacogenomics-carbamazepine-normalizes-activation-and-attenuates-thermal-induced-hyperexcitability-of-sensory-neurons-due-to-nav1-7-mutation-i234t
#12
Yang Yang, Talia Adi, Philip Effraim, Lubin Chen, Sulayman D Dib-Hajj, Stephen G Waxman
BACKGROUND AND PURPOSE: Pharmacotherapy for pain currently involves trial-and-error. A previous study on inherited erythromelalgia (a genetic model of neuropathic pain due to mutations in voltage-gated sodium channel Nav1.7) used genomics, structural modeling, biophysical and pharmacological analyses to guide pharmacotherapy, and showed that carbamazepine normalizes voltage-dependence of activation of the Nav1.7-S241T mutant channel, reducing pain in patients carrying this mutation. However, whether this approach is applicable to other Nav mutations is still unknown...
June 28, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28652197/emergence-of-drug-resistant-bacteria-at-the-hajj-a-systematic-review
#13
REVIEW
Thongpan Leangapichart, Jean-Marc Rolain, Ziad A Memish, Jaffar A Al-Tawfiq, Philippe Gautret
BACKGROUND: Hajj is the annual mass gathering of Muslims, and is a reservoir and potential source of bacterial transmission. The emergence of bacterial transmission, including multi-drug resistance (MDR) bacteria, during Hajj has not been systematically assessed. METHODS: Articles in Pubmed, Scopus, and Google scholar were identified using controlled words relating to antibiotic resistance (AR) at the Hajj from January 2002 to January 2017. Eligible studies were identified by two researchers...
June 23, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/28651902/ercp-and-laparoscopic-cholecystectomy-in-a-patient-with-situs-inversus-totalis
#14
Ihab I El Hajj, Stuart Sherman, Eugene P Ceppa, Glen A Lehman
No abstract text is available yet for this article.
June 7, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28641999/effect-of-pharmacist-care-on-medication-adherence-and-cardiovascular-outcomes-among-patients-post-acute-coronary-syndrome-a%C3%A2-systematic-review
#15
REVIEW
Maguy Saffouh El Hajj, Myriam Jihad Jaam, Ahmed Awaisu
BACKGROUND: The impact of collaborative and multidisciplinary health care on the outcomes of care in patients with acute coronary syndromes (ACS) is well-established in the literature. However, there is lack of high quality evidence on the role of pharmacist care in this setting. OBJECTIVE: This systematic review aimed to evaluate the impact of pharmacist care on patient outcomes (readmission, mortality, emergency visits, and medication adherence) in patients with ACS at or post-discharge...
June 13, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28625816/a-prospective-multicenter-study-evaluating-learning-curves-and-competence-in-endoscopic-ultrasound-and-endoscopic-retrograde-cholangiopancreatography-among-advanced-endoscopy-trainees-the-rapid-assessment-of-trainee-endoscopy-skills-rates-study
#16
Sachin Wani, Rajesh Keswani, Matt Hall, Samuel Han, Meer Akbar Ali, Brian Brauer, Linda Carlin, Amitabh Chak, Dan Collins, Gregory A Cote, David L Diehl, Christopher J DiMaio, Andrew Dries, Ihab El-Hajj, Swan Ellert, Kimberley Fairley, Ashley Faulx, Larissa Fujii-Lau, Srinivas Gaddam, Seng-Ian Gan, Jonathan P Gaspar, Chitiki Gautamy, Stuart Gordon, Cynthia Harris, Sarah Hyder, Ross Jones, Stephen Kim, Srinadh Komanduri, Ryan Law, Linda Lee, Rawad Mounzer, Daniel Mullady, V Raman Muthusamy, Mojtaba Olyaee, Patrick Pfau, Shreyas Saligram, Cyrus Piraka, Amit Rastogi, Laura Rosenkranz, Fadi Rzouq, Aditi Saxena, Raj J Shah, Violette C Simon, Aaron Small, Jayaprakash Sreenarasimhaiah, Andrew Walker, Andrew Y Wang, Rabindra R Watson, Robert H Wilson, Patrick Yachimski, Dennis Yang, Steven Edmundowicz, Dayna S Early
BACKGROUND AND AIMS: Based on the Next Accreditation System, trainee assessment should occur on a continuous basis with individualized feedback. We aimed to validate endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) learning curves among advanced endoscopy trainees (AETs) using a large national sample of training programs and to develop a centralized database that allows assessment of performance in relation to peers. METHODS: ASGE recognized training programs were invited to participate and AETs were graded on ERCP and EUS exams using a validated competency assessment tool that assesses technical and cognitive competence in a continuous fashion...
June 15, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28619754/antitumor-effect-of-the-atypical-retinoid-st1926-in-acute-myeloid-leukemia-and-nanoparticle-formulation-prolongs-lifespan-and-reduces-tumor-burden-of-xenograft-mice
#17
Leeanna El-Houjeiri, Walid Saad, Berthe Hayar, Patrick Aouad, Nadim Tawil, Rana Abdel-Samad, Rita Hleihel, Maguy Hamie, Angelo Mancinelli, Claudio Pisano, Hiba El Hajj, Nadine Darwiche
Acute myeloid leukemia (AML) is one of the most frequent types of blood malignancies. It is a complex disorder of undifferentiated hematopoietic progenitor cells. The majority of patients generally respond to intensive therapy. Nevertheless, relapse is the major cause of death in AML, warranting the need for novel treatment strategies. Retinoids have demonstrated potent differentiation and growth regulatory effects in normal, transformed and hematopoietic progenitor cells. All-trans retinoic acid (ATRA) is the paradigm of treatment in acute promyelocytic leukemia, an AML subtype...
June 15, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28619416/mass-gatherings-and-public-health-case-studies-from-the-hajj-to-mecca
#18
Juma Rahman, Min Thu, Neelam Arshad, Marc Van der Putten
BACKGROUND: Many new and challenging risks can be introduced during mass gatherings. The Hajj, as one of the largest mass gatherings, provides an excellent annual opportunity to reflect on the public health risk posed by international and multicultural crowds and the value of mitigation strategies. OBJECTIVES: To identify the gap between preparation and training taken before being exposed to the mass gathering and postexposure experiences, and the breach between the expectations and reality of the holy place...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28609400/cytomegalovirus-viraemia-is-associated-with-poor-growth-and-t-cell-activation-with-an-increased-burden-in-hiv-exposed-uninfected-infants
#19
Miguel A Garcia-Knight, Eunice Nduati, Amin S Hassan, Irene Nkumama, Timothy J Etyang, Naseem J Hajj, Faith Gambo, Denis Odera, James A Berkley, Sarah L Rowland-Jones, Britta Urban
OBJECTIVE: Factors associated with poor health in HIV-exposed-uninfected (HEU) infants are poorly defined. We describe the prevalence and correlates of CMV viraemia in HEU and HIV-unexposed-uninfected (HUU) infants, and quantify associations with anthropometric, haematological and immunological outcomes. DESIGN: Cross-sectional, including HEU and HUU infants from rural coastal Kenya. METHODS: Infants aged 2-8 months were studied. The primary outcome was CMV viraemia and viral load, determined by quantitative PCR...
June 12, 2017: AIDS
https://www.readbyqxmd.com/read/28606757/myeloid-sarcoma-of-the-sigmoid-colon-an-unusual-presentation-of-a-rare-condition
#20
Ihab I El Hajj, Jeffrey J Easler, Eugene P Ceppa, Safi Shahda
No abstract text is available yet for this article.
May 24, 2017: Digestive and Liver Disease
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