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https://www.readbyqxmd.com/read/29031546/influenza-virus-but-not-mers-coronavirus-circulation-in-iran-2013-2016-comparison-between-pilgrims-and-general-population
#1
Jila Yavarian, Nazanin Zahra Shafiei Jandaghi, Maryam Naseri, Peyman Hemmati, Mohhamadnasr Dadras, Mohammad Mehdi Gouya, Talat Mokhtari Azad
BACKGROUND: The pilgrimage to Mecca and Karbala bring many Muslims to a confined area. Respiratory tract infections are the most common diseases transmitted during mass gatherings in Hajj, Umrah and Karbala. The aim of this study was to determine and compare the prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) and influenza virus infections among Iranian general population and pilgrims with severe acute respiratory infections (SARI) returning from Mecca and Karbala during 2013-2016...
October 11, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29030774/effects-of-growth-hormone-therapy-on-bone-density-and-fracture-risk-in-age-related-osteoporosis-in-the-absence-of-growth-hormone-deficiency-a-systematic-review-and-meta-analysis
#2
Maya Barake, Asma Arabi, Nancy Nakhoul, Ghada El-Hajj Fuleihan, Sarah El Ghandour, Anne Klibanski, Nicholas A Tritos
PURPOSE: In adults, growth hormone deficiency (GHD) has been associated with low bone mineral density (BMD), an effect counteracted by growth hormone (GH) replacement. Whether GH is beneficial in adults with age-related bone loss and without hypopituitarism is unclear. METHODS: We conducted a systematic literature search using Medline, Embase and the Cochrane Register of Controlled Trials. We extracted and analyzed data according to the bone outcome included [bone mineral content (BMC), BMD, and bone biomarker, fracture risk]...
October 13, 2017: Endocrine
https://www.readbyqxmd.com/read/29026699/comparison-of-the-clinical-biological-width-with-the-published-standard-histologic-mean-values
#3
Fatme Mouchref Hamasni, Fady El Hajj
AIMS AND OBJECTIVES: Biologic width (BW) as defined by Cohen is the part of the supracrestal gingival tissues that occupy the space between the base of the gingival crevice and the alveolar crest; it includes the junctional epithelium and the connective tissue element. Interactions between dental crowns and the marginal periodontal tissues analyzed in many review papers concluded that the recognition of the BW, in terms of crown margin placement, is beneficial for periodontal health. Therefore, knowledge of the dimensions of the sum of the junctional epithelium and connective tissue attachment as well as the sulcus depth (SD) is of clinical relevance...
September 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29016303/undiagnosed-active-pulmonary-tuberculosis-among-pilgrims-during-the-2015-hajj-mass-gathering-a-prospective-cross-sectional-study
#4
Saber Yezli, Alimuddin Zumla, Yara Yassin, Ali M Al-Shangiti, Gamal Mohamed, Abdulhafiz M Turkistani, Badriah Alotaibi
Mass gatherings pose a risk for tuberculosis (TB) transmission and reactivation of latent TB infection. The annual Hajj pilgrimage attracts 2 million pilgrims from high TB-endemic countries. We evaluated the burden of undiagnosed active pulmonary TB in pilgrims attending the 2015 Hajj mass gathering. We conducted a prospective cross-sectional study in Mecca, Kingdom of Saudi Arabia, for nonhospitalized adult pilgrims from five high TB-endemic countries. Enrollment criteria were the presence of a cough and the ability to produce a sputum sample...
September 5, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28991221/a-non-coding-function-of-tyrp1-mrna-promotes-melanoma-growth
#5
David Gilot, Mélodie Migault, Laura Bachelot, Fabrice Journé, Aljosja Rogiers, Emmanuelle Donnou-Fournet, Ariane Mogha, Nicolas Mouchet, Marie-Laure Pinel-Marie, Bernard Mari, Tristan Montier, Sébastien Corre, Arthur Gautron, Florian Rambow, Petra El Hajj, Rania Ben Jouira, Sophie Tartare-Deckert, Jean-Christophe Marine, Brice Felden, Ghanem Ghanem, Marie-Dominique Galibert
Competition among RNAs to bind miRNA is proposed to influence biological systems. However, the role of this competition in disease onset is unclear. Here, we report that TYRP1 mRNA, in addition to encoding tyrosinase-related protein 1 (TYRP1), indirectly promotes cell proliferation by sequestering miR-16 on non-canonical miRNA response elements. Consequently, the sequestered miR-16 is no longer able to repress its mRNA targets, such as RAB17, which is involved in melanoma cell proliferation and tumour growth...
October 9, 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/28958788/life-threatening-hemobilia-after-endoscopic-retrograde-cholangiopancreatography-ercp
#6
Ihab I El Hajj, Stuart Sherman, Maximilian Pyko, Glen A Lehman
Arterial vascular complication from endoscopic retrograde cholangiopancreatography (ERCP) is exceedingly rare. This report describes a life threatening hemobilia, from a pseudoaneurysm of the right hepatic artery (RHA), which occurred post ERCP. The pseudoaneurysm and the active bleed were diagnosed by selective angiography of the RHA, and successfully treated with stenting.
September 11, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28958141/oral-manifestations-of-inflammatory-bowel-disease
#7
I Mortada, A Leone, A Gerges Geagea, R Mortada, C Matar, M Rizzo, I Hajj Hussein, L Massaad-Massade, A Jurjus
Inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis, have important extraintestinal manifestations, notably in the oral cavity. These oral manifestations can constitute important clinical clues in the diagnosis and management of IBD, and include changes at the immune and bacterial levels. Aphthous ulcers, pyostomatitis vegetans, cobblestoning and gingivitis are important oral findings frequently observed in IBD patients. Their presentations vary considerably and might be well diagnosed and distinguished from other oral lesions...
July 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28930004/enteric-infections-circulating-during-hajj-seasons-2011-2013
#8
Moataz Abd El Ghany, Mona Alsomali, Malak Almasri, Eriko Padron Regalado, Raeece Naeem, AbdulHafeez Tukestani, Abdullah Asiri, Grant A Hill-Cawthorne, Arnab Pain, Ziad A Memish
Hajj, the annual Muslim pilgrimage to Mecca, Saudi Arabia, is a unique mass gathering event that raises public health concerns in the host country and globally. Although gastroenteritis and diarrhea are common among Hajj pilgrims, the microbial etiologies of these infections are unknown. We collected 544 fecal samples from pilgrims with medically attended diarrheal illness from 40 countries during the 2011-2013 Hajj seasons and screened the samples for 16 pathogens commonly associated with diarrheal infections...
October 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28928702/workplace-ostracism-seen-through-the-lens-of-power
#9
John Fiset, Raghid Al Hajj, John G Vongas
Drawing on approach/inhibition theory of power, we investigated two factors that influence the manner by which victims react to workplace ostracism: the hierarchical status of the ostracizer and the level of an ostracizee's external social support including family, friends, and significant others. Across an experimental vignette study (Study 1) and a field study (Study 2), we found support for a three-way interaction with felt ostracism, ostracizee external social support, and ostracizer status influencing victims' organizational citizenship behavior and deviance directed toward other individuals...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28927837/accidental-fracture-of-an-eus-fna-needle
#10
Ihab I El Hajj, Mark A Gromski, Glen A Lehman, Jeffrey J Easler, Stuart Sherman
No abstract text is available yet for this article.
September 16, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28916222/estimating-vocal-effort-from-the-aerodynamics-of-labial-fricatives-a-feasibility-study
#11
Yohann Meynadier, Anita El Hajj, Michel Pitermann, Thierry Legou, Antoine Giovanni
OBJECTIVE AND HYPOTHESIS: Vocal effort in loud voice is produced with increased subglottal pressure during vowels and increased supraglottal pressure during consonants. In the paper, our main objective is to check whether it was supported by a parallel increase in the airflow resistance of the laryngeal articulator and of the supralaryngeal articulator, here the lips. STUDY DESIGN AND METHOD: For this comparison, our choice fell on the fricative consonants, as their production allows perfectly synchronous air pressure and airflow measurements...
September 12, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28895928/collaborative-visual-analytics-a-health-analytics-approach-to-injury-prevention
#12
Samar Al-Hajj, Brian Fisher, Jennifer Smith, Ian Pike
Background: Accurate understanding of complex health data is critical in order to deal with wicked health problems and make timely decisions. Wicked problems refer to ill-structured and dynamic problems that combine multidimensional elements, which often preclude the conventional problem solving approach. This pilot study introduces visual analytics (VA) methods to multi-stakeholder decision-making sessions about child injury prevention; Methods: Inspired by the Delphi method, we introduced a novel methodology-group analytics (GA)...
September 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28888826/intramural-duodenal-hematoma-post-eus-guided-placement-of-fiducial-radiopaque-markers
#13
Ihab I El Hajj, Jeffrey J Easler, Stuart Sherman, Mohammad Al-Haddad
No abstract text is available yet for this article.
August 24, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28867782/the-canadian-atlas-of-child-and-youth-injury-mobilizing-injury-surveillance-data-to-launch-a-national-knowledge-translation-tool
#14
Ian Pike, Jennifer Smith, Samar Al-Hajj, Pamela Fuselli, Alison Macpherson
Child and youth injury prevention research in Canada has lagged behind other Organisation for Economic Co-operation and Development nations, despite existing surveillance systems and longitudinal data. A critical need to improve access to the available data, as well as need to tailor its display and interpretation, was identified by injury prevention stakeholders involved in research, policy, and practice. The Canadian Atlas of Child and Youth Injury Prevention ("the Atlas") was developed to address this need...
August 30, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28866827/fistula-following-laparoscopic-sleeve-gastrectomy-a-proposed-classification-and-algorithm-for-optimal-management
#15
G Al Hajj, R Chemaly
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is an accepted restrictive procedure with a hormonal component. There is no definitive course of treatment for post-LSG fistula; it remains a feared complication. We aimed to classify post-LSG fistulas and propose an algorithm to optimize their treatment. METHODS: Following primary and revisional LSG in obese patients, a retrospective observational study of fistulas was undertaken. Radiological studies were performed to identify anatomically distinct types of fistulas...
September 2, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28854270/hypermethylation-of-the-non-imprinted-maternal-meg3-and-paternal-mest-alleles-is-highly-variable-among-normal-individuals
#16
Larissa Haertle, Anna Maierhofer, Julia Böck, Harald Lehnen, Yvonne Böttcher, Matthias Blüher, Martin Schorsch, Ramya Potabattula, Nady El Hajj, Silke Appenzeller, Thomas Haaf
Imprinted genes show parent-specific activity (functional haploidy), which makes them particularly vulnerable to epigenetic dysregulation. Here we studied the methylation profiles of oppositely imprinted genes at single DNA molecule resolution by two independent parental allele-specific deep bisulfite sequencing (DBS) techniques. Using Roche (GSJunior) next generation sequencing technology, we analyzed the maternally imprinted MEST promoter and the paternally imprinted MEG3 intergenic (IG) differentially methylated region (DMR) in fetal cord blood, adult blood, and visceral adipose tissue...
2017: PloS One
https://www.readbyqxmd.com/read/28829831/no-significant-htlv-seroprevalence-in-german-people-who-inject-drugs
#17
Oliver Hohn, Stephen Norley, Claudia Kücherer, Ali Bazarbachi, Hiba El Hajj, Ulrich Marcus, Ruth Zimmermann, Norbert Bannert
BACKGROUND: Although human T-lymphotropic virus (HTLV) is transmitted via the same routes as human immunodeficiency virus (HIV), its worldwide seroprevalence differs drastically because HTLV is transmitted mainly via infected cells rather than free virus. The sharing of needles and other equipment places people who inject drugs (PWID) at particularly high-risk for such blood-borne diseases. METHODS: To validate the methodology used to process and analyze the dried blood spots (DBS) utilized in the study, dried serum spots (DSS) with dilutions of sera from known HTLV infected individuals were analyzed by ELISA and Western blot...
2017: PloS One
https://www.readbyqxmd.com/read/28803813/the-challenges-of-cholera-at-the-2017-hajj-pilgrimage
#18
Alimuddin Zumla, Brian McCloskey, Tina Endericks, Esam I Azhar, Eskild Petersen
No abstract text is available yet for this article.
August 10, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28780980/impact-of-the-hajj-on-pneumococcal-carriage-and-the-effect-of-various-pneumococcal-vaccines
#19
REVIEW
Sophie Edouard, Jaffar A Al-Tawfiq, Ziad A Memish, Saber Yezli, Philippe Gautret
BACKGROUND: The Islamic Hajj pilgrimage is the largest annual mass gathering in the world. The overcrowding of people promotes the acquisition, spread and transmission of respiratory pathogens, including Streptococcus pneumoniae. It is estimated that about 33% of pilgrims are at risk of invasive pneumococcal disease. METHODS: We conducted a methodological review according to the Preferred Reporting Items for Systematic Reviews and meta-Analysis guidelines. The objective was to summarize the available data regarding the prevalence of pneumococcal carriage among Hajj pilgrims and about carriage acquisition and circulation of S...
August 7, 2017: Vaccine
https://www.readbyqxmd.com/read/28778024/a-combination-of-radiation-and-the-hypoxia-activated-prodrug-evofosfamide-th-302-is-efficacious-against-a-human-orthotopic-pancreatic-tumor-model
#20
Carla Hajj, James Russell, Charles P Hart, Karyn A Goodman, Maeve A Lowery, Adriana Haimovitz-Friedman, Joseph O Deasy, John L Humm
This study was designed to investigate the effect of single-dose radiation therapy (RT) in combination with evofosfamide (TH-302), a hypoxia-activated prodrug, in a pre-clinical model of pancreatic cancer. AsPC1 tumors were implanted orthotopically in the pancreas of nude mice. Tumors were treated with 15 Gy of RT, using a 1 cm diameter field, and delivered as a continuous arc. Image-guidance to center the field on the tumor was based on CT imaging with intraperitoneal contrast. Evofosfamide (100 mg/kg, i.p...
October 2017: Translational Oncology
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