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A Positive Diagnostic Strategy Is Noninferior to a Strategy of Exclusion for Patients With Irritable Bowel Syndrome

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https://www.readbyqxmd.com/read/23357491/a-positive-diagnostic-strategy-is-noninferior-to-a-strategy-of-exclusion-for-patients-with-irritable-bowel-syndrome
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RANDOMIZED CONTROLLED TRIAL
Luise M Begtrup, Anne Line Engsbro, Jens Kjeldsen, Pia V Larsen, Ove Schaffalitzky de Muckadell, Peter Bytzer, Dorte E Jarbøl
BACKGROUND & AIMS: Guidelines recommend a positive strategy based on symptom criteria to diagnose patients with irritable bowel syndrome (IBS). We conducted a randomized noninferiority trial to determine whether a positive diagnostic strategy is noninferior to a strategy of exclusion, with regard to patients' health-related quality of life (HRQOL). METHODS: We studied 302 patients (18-50 years old) from primary care who were suspected of having IBS and referred by general practitioners...
August 2013: Clinical Gastroenterology and Hepatology
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