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https://www.readbyqxmd.com/read/29785917/effect-of-season-and-breed-on-physiological-and-blood-parameters-in-buffaloes
#1
Liu Shenhe, Li Jun, Li Zipeng, Deng Tingxian, Zia Ur Rehman, Zhou Zichao, Yang Liguo
In this Research Communication we describe the effect of temperature and humidity index (THI) on various physiological traits, the plasma heat shock protein 70 (HSP70), heat shock protein 90 (HSP90) and cortisol levels and other blood parameters in crossbred buffalo (Nili-Ravi × Murrah) and Mediterranean buffalo to compare their tolerance to heat stress. As expected, crossbred buffalo had a significantly higher rectal temperature (RT), body surface temperature (BT), respiratory rate (RR), HSP70 and HSP90 levels in summer compared to spring and winter...
May 2018: Journal of Dairy Research
https://www.readbyqxmd.com/read/29785071/identification-of-cis-regulatory-elements-associated-with-salinity-and-drought-stress-tolerance-in-rice-from-co-expressed-gene-interaction-networks
#2
Pragya Mishra, Nisha Singh, Ajay Jain, Neha Jain, Vagish Mishra, Pushplatha G, Kiran P Sandhya, Nagendra Kumar Singh, Vandna Rai
Rice, a staple food crop, is often subjected to drought and salinity stresses thereby limiting its yield potential. Since there is a cross talk between these abiotic stresses, identification of common and/or overlapping regulatory elements is pivotal for generating rice cultivars that showed tolerance towards them. Analysis of the gene interaction network (GIN) facilitates identifying the role of individual genes and their interactions with others that constitute important molecular determinants in sensing and signaling cascade governing drought and/or salinity stresses...
2018: Bioinformation
https://www.readbyqxmd.com/read/29783951/the-transcriptomic-and-proteomic-responses-of-daphnia-pulex-to-changes-in-temperature-and-food-supply-comprise-environment-specific-and-clone-specific-elements
#3
Dörthe Becker, Yann Reydelet, Jacqueline A Lopez, Craig Jackson, John K Colbourne, Susan Hawat, Michael Hippler, Bettina Zeis, Rüdiger J Paul
BACKGROUND: Regulatory adjustments to acute and chronic temperature changes are highly important for aquatic ectotherms because temperature affects their metabolic rate as well as the already low oxygen concentration in water, which can upset their energy balance. This also applies to severe changes in food supply. Thus, we studied on a molecular level (transcriptomics and/or proteomics) the immediate responses to heat stress and starvation and the acclimation to different temperatures in two clonal isolates of the model microcrustacean Daphnia pulex from more or less stressful environments, which showed a higher (clone M) or lower (clone G) tolerance to heat and starvation...
May 21, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29782030/the-genomes-of-three-bradyrhizobium-sp-isolated-from-root-nodules-of-lupinus-albescens-grown-in-extremely-poor-soils-display-important-genes-for-resistance-to-environmental-stress
#4
Camille E Granada, Luciano K Vargas, Fernando Hayashi Sant'Anna, Eduardo Balsanelli, Valter Antonio de Baura, Fábio de Oliveira Pedrosa, Emanuel Maltempi de Souza, Tiago Falcon, Luciane M P Passaglia
Lupinus albescens is a resistant cover plant that establishes symbiotic relationships with bacteria belonging to the Bradyrhizobium genus. This symbiosis helps the development of these plants in adverse environmental conditions, such as the ones found in arenized areas of Southern Brazil. This work studied three Bradyrhizobium sp. (AS23, NAS80 and NAS96) isolated from L. albescens plants that grow in extremely poor soils (arenized areas and adjacent grasslands). The genomes of these three strains were sequenced in the Ion Torrent platform using the IonXpress library preparation kit, and presented a total number of bases of 1,230,460,823 for AS23, 1,320,104,022 for NAS80, and 1,236,105,093 for NAS96...
May 17, 2018: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/29780273/ectopic-ring-zinc-finger-gene-from-hot-pepper-induces-totally-different-genes-in-lettuce-and-tobacco
#5
Mahipal Singh Kesawat, Dong Kyun Kim, Naheed Zeba, Mi Chung Suh, Xinli Xia, Choo Bong Hong
Advances in molecular biology have improved crops through transferring genes from one organism to new hosts, and these efforts have raised concerns about potential unexpected outcomes. Here, we provide evidence that a gene with a specific function in one organism can yield completely different effects in a new host. CaRZFP1 is a C3HC4-type RING zinc finger protein gene previously isolated from a cDNA library for heat-stressed hot pepper. In our previous work investigating in vivo CaRZFP1 function, we transferred CaRZFP1 into tobacco; transgenic tobacco exhibited enhanced growth and tolerance to abiotic stresses...
2018: Molecular Breeding: New Strategies in Plant Improvement
https://www.readbyqxmd.com/read/29780215/expression-of-a-rice-soluble-starch-synthase-gene-in-transgenic-wheat-improves-the-grain-yield-under-heat-stress-conditions
#6
Bin Tian, Shyamal K Talukder, Jianming Fu, Allan K Fritz, Harold N Trick
Wheat ( Triticum aestivum L.) is a temperate cereal with an optimum temperature range of 15-22°C during the grain filling stage. Heat stress is one of the major environmental constraints for wheat production worldwide. Temperatures above 25°C during the grain filling stage significantly reduced wheat yield and quality. This reduction was reported due to the inactivation of the soluble starch synthase, a key heat-labile enzyme in starch transformation of wheat endosperm. To improve wheat productivity under heat stress, the rice soluble starch synthase I, under the control of either a constitutive promoter or an endosperm-specific promoter, was expressed in wheat and the transgenic lines were monitored for expression and the effects on yield-related traits...
2018: In Vitro Cellular & Developmental Biology. Plant: Journal of the Tissue Culture Association
https://www.readbyqxmd.com/read/29779966/developing-and-deploying-climate-resilient-maize-varieties-in-the-developing-world
#7
REVIEW
Jill E Cairns, B M Prasanna
In sub-Saharan Africa (SSA) and Asia maize yields remain variable due to climate shocks. Over the past decade extensive progress has been made on the development and delivery of climate-resilient maize. In 2016 over 70000 metric tonnes of drought-tolerant maize seed was commercialized in 13 countries in SSA, benefiting an estimated 53 million people. Significant progress is also being made with regard to the development and deployment of elite heat-tolerant maize varieties in South Asia. Increased genetic gain in grain yield under stress-prone environments, coupled with faster replacement of old/obsolete varieties, through intensive engagement with seed companies is essential to protect maize crops grown by smallholders from the changing climates in SSA and Asia...
May 17, 2018: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/29775421/probability-of-heat-intolerance-standardized-interpretation-of-heat-tolerance-testing-results-versus-specialist-judgment
#8
Haggai Schermann, Erin Craig, Einat Yanovich, Itay Ketko, Gary Kalmanovich, Ran Yanovich
CONTEXT:   The heat-tolerance test (HTT) is a screening tool for secondary prevention of exertional heat illness by the Israel Defense Forces. To discern participant tolerance, recruits are exposed to intermediate environmental and exercise stresses, and their physiological responses, core temperature, and heart rate are monitored. When their physiological measures rise at a higher rate or exceed the upper levels of absolute values compared with other participants, heat intolerance (HI) is diagnosed...
April 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29774830/frequent-implication-of-multistress-tolerant-campylobacter-jejuni-in-human-infections
#9
Euna Oh, Linda Chui, Junghee Bae, Vincent Li, Angela Ma, Steven K Mutschall, Eduardo N Taboada, Lynn M McMullen, Byeonghwa Jeon
Campylobacter jejuni, a major cause of bacterial foodborne illnesses, is considered highly susceptible to environmental stresses. In this study, we extensively investigated the stress tolerance of 121 clinical strains of C. jejuni against 5 stress conditions (aerobic stress, disinfectant exposure, freeze-thaw, heat treatment, and osmotic stress) that this pathogenic bacterium might encounter during foodborne transmission to humans. In contrast to our current perception about high stress sensitivity of C. jejuni, a number of clinical strains of C...
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29774556/physiological-response-of-tomatoes-at-drought-heat-and-their-combination-followed-by-recovery
#10
Rong Zhou, Lingpeng Kong, Zhen Wu, Eva Rosenqvist, Yinlei Wang, Liping Zhao, Tongmin Zhao, Carl-Otto Ottosen
In nature, crops encounter a combination of abiotic stresses that severely limit yield. Our aim was to dynamically expose the changes of tomatoes' physiological parameters to drought, heat and their combination and thereby clarify the relationship between the responses to single and combined stress. We studied the effect of single and combined drought and heat stresses on the shoot and root of two tomato cultivars (Sufen No.14 as CV1; Jinlingmeiyu as CV2). After being exposed to combined stress for six days, the dry weight of shoot and root significantly decreased...
May 17, 2018: Physiologia Plantarum
https://www.readbyqxmd.com/read/29766507/abscisic-acid-prevents-pollen-abortion-under-high-temperature-stress-by-mediating-sugar-metabolism-in-rice-spikelets
#11
Md Rezaul Islam, Baohua Feng, Tingting Chen, Weimeng Fu, Caixia Zhang, Longxing Tao, Guanfu Fu
Heat stress at the pollen mother cell (PMC) meiotic stage leads to pollen sterility in rice, in which the reactive oxygen species (ROS) and sugar homeostasis are always adversely affected. This damage is reversed by abscisic acid (ABA), but the mechanisms underlying the interactions among the ABA, sugar metabolism, ROS and heat shock proteins (HSPs) in rice spikelets under heat stress are unclear. Two rice genotypes, Zhefu802 (a recurrent parent) and fgl (its near-isogenic line) were subjected to heat stress of 40°C after pre-foliage sprayed with ABA and its biosynthetic inhibitor fluridone at the meiotic stage of PMC...
May 16, 2018: Physiologia Plantarum
https://www.readbyqxmd.com/read/29763329/fullerene-cation-mediated-noble-metal-free-direct-introduction-of-functionalized-aryl-groups-onto-60-fullerene
#12
Xiao-Yu Yang, Hao-Sheng Lin, Il Jeon, Yutaka Matsuo
Aryl[60]fullerenyl cations (ArC60 + ), which were generated by heating aryl[60]fullerenyl dimers (ArC60 -C60 Ar) to generate aryl[60]fullerenyl radicals (ArC60 • ) followed by oxidation using Cu(II) salts (Cu(BF4 )2 (aq)), were reacted with various functionalized aryl boronic acids to produce functionalized 1,4-diaryl[60]fullerenes. This protocol tolerated various functional groups, such as OH, NH2 , COCH3 , and Cl substituents, with yields reaching 93%. C60 Ar1 Ar2 (Ar2 = p-NH2 C6 H4 ) was used as a dopant in a photoactive CH3 NH3 PbI3 layer of a perovskite solar cell...
May 15, 2018: Organic Letters
https://www.readbyqxmd.com/read/29760715/higher-temperature-at-lower-elevation-sites-fails-to-promote-acclimation-or-adaptation-to-heat-stress-during-pollen-germination
#13
Lluvia Flores-Rentería, Amy V Whipple, Gilbert J Benally, Adair Patterson, Brandon Canyon, Catherine A Gehring
High temperatures associated with climate change are expected to be detrimental for aspects of plant reproduction, such as pollen viability. We hypothesized that (1) higher peak temperatures predicted with climate change would have a minimal effect on pollen viability, while high temperatures during pollen germination would negatively affect pollen viability, (2) high temperatures during pollen dispersal would facilitate acclimation to high temperatures during pollen germination, and (3) pollen from populations at sites with warmer average temperatures would be better adapted to high temperature peaks...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29760078/chaperone-ampylation-modulates-aggregation-and-toxicity-of-neurodegenerative-disease-associated-polypeptides
#14
Matthias C Truttmann, David Pincus, Hidde L Ploegh
Proteostasis is critical to maintain organismal viability, a process counteracted by aging-dependent protein aggregation. Chaperones of the heat shock protein (HSP) family help control proteostasis by reducing the burden of unfolded proteins. They also oversee the formation of protein aggregates. Here, we explore how AMPylation, a posttranslational protein modification that has emerged as a powerful modulator of HSP70 activity, influences the dynamics of protein aggregation. We find that adjustments of cellular AMPylation levels in Caenorhabditis elegans directly affect aggregation properties and associated toxicity of amyloid-β (Aβ), of a polyglutamine (polyQ)-extended polypeptide, and of α-synuclein (α-syn)...
May 14, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29756579/recent-changes-in-the-management-of-patients-with-food-allergy-in-a-tertiary-referral-centre-a-dietitian-s-perspective
#15
Rachel de Boer, Ruth Chalmers
It is has been suggested that the prevalence of food allergy has increased over the last few decades with estimates now suggesting between 3.9-8% of children are food allergic (Kattan, 2016). Studies also suggest that rates of food allergy resolution are slowing, meaning more children are remaining allergic for longer (Sicherer et al, 2014). The mainstay of food allergy management is dietary exclusion of known food allergen/s. Exclusion diets are frequently difficult for patients and their families to manage and the literature highlights that they impact negatively on quality of life (Valentine et al, 2011) ...
May 14, 2018: Current Pediatric Reviews
https://www.readbyqxmd.com/read/29753120/a-phase-i-trial-of-surgical-resection-and-intraoperative-hyperthermic-cisplatin-and-gemcitabine-for-pleural-mesothelioma
#16
Bryan M Burt, William G Richards, Hyun-Sung Lee, Sylvia Bartel, Marcelo C Dasilva, Ritu R Gill, Michael T Jaklitsch, Bruce E Johnson, Scott J Swanson, Raphael Bueno, David J Sugarbaker
INTRODUCTION: The primary objective of this single-institution Phase I clinical trial was to establish the maximum tolerated dose (MTD) of gemcitabine added to cisplatin delivered as heated intraoperative chemotherapy (HIOC) following resection of malignant pleural mesothelioma (MPM). METHODS: Extrapleural pneumonectomy (EPP) and pleurectomy/decortication (P/D) treatment arms were based on investigators' assessment of patient fitness and potential for macroscopic complete resection...
May 9, 2018: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29752352/functional-analysis-of-hsh155-sf3b1-interactions-with-the-u2-snrna-branch-site-duplex
#17
Tucker Joe Carrocci, Joshua Clark Paulson, Aaron Andrew Hoskins
SF3b1 is an essential component of the U2 snRNP implicated in branch site (BS) recognition and found to be frequently mutated in several human cancers. While recent structures of yeast and human SF3b1 have revealed its molecular architecture, the importance of specific RNA:protein contacts and conformational changes remain largely uncharacterized. Here, we performed mutational analysis of yeast SF3b1, guided by recent structures of the spliceosome. We find that conserved amino acids contacting the U2 snRNA backbone of the U2/BS duplex are nonessential, and that yeast can tolerate truncation of the HEAT repeats containing these amino acids...
May 11, 2018: RNA
https://www.readbyqxmd.com/read/29750330/antagonism-against-fish-pathogens-by-cellular-components-preparations-of-bacillus-coagulans-mtcc-9872-and-it-s-in-vitro-probiotic-characterisation
#18
Sebastian J Midhun, Sahadevan Neethu, A Vysakh, E K Radhakrishnan, Mathew Jyothis
Bacterial fish pathogens are pervasive in aquaculture. Control of bacterial fish pathogen is a difficult task among aquaculture practitioners. A large number of antibiotics are used for the control of prevalent bacterial pathogens in aquaculture. This may lead to drug resistance among pathogens and further treatment will be ineffective. Here, we can use probiotic bacteria as a biocontrol agent in fish disease and it is a novel field. In this study, antimicrobial potential of the bacterium Bacillus coagulans (MTCC-9872) has been evaluated through in vitro antagonistic activity of cellular preparations/components against potent pathogens...
May 10, 2018: Current Microbiology
https://www.readbyqxmd.com/read/29749536/biib021-an-hsp90-inhibitor-a-promising-therapeutic-strategy-for-blood-malignancies-review
#19
Wei He, Huixian Hu
Heat shock proteins (HSPs) are molecular chaperones that are consistently increased to help cells survive under conditions of stress. As a member of the Hsps, Hsp90 is involved in protein post‑translational maturation and disposition. This protein is ubiquitously expressed in normal cells. However, in cancer cells and particularly in hematological malignancies, Hsp90 is unexpectedly abundant to maintain levels of proteins vital for cancer pathology. Hsp90 inhibitors can target the ATP domain of Hsp90 and prohibit its exchange of ADP for ATP, leading to the degradation of client proteins and disruption of signaling cascades...
May 8, 2018: Oncology Reports
https://www.readbyqxmd.com/read/29746879/characterization-of-novel-heat-responsive-transcription-factor-tahsfa6e-gene-involved-in-regulation-of-heat-shock-proteins-hsps-a-key-member-of-heat-stress-tolerance-network-of-wheat
#20
Ranjeet R Kumar, Suneha Goswami, Khushboo Singh, Kavita Dubey, Gyanendra K Rai, Bhupinder Singh, Shivdhar Singh, Monendra Grover, Dwijesh Mishra, Sanjeev Kumar, Suman Bakshi, Anil Rai, Himanshu Pathak, Viswanathan Chinnusamy, Shelly Praveen
Heat stress has an adverse effect on the quality and quantity of agriculturally important crops, especially wheat. The tolerance mechanism has not been explored much in wheat and very few genes/ TFs responsive to heat stress is available on public domain. Here, we identified, cloned and characterized a putative TaHSFA6e TF gene of 1.3 kb from wheat cv. HD2985. We observed an ORF of 368 aa with Hsf DNA binding signature domain in the amino acid sequence. Single copy number of TaHSFA6e was observed integrated in the genome of wheat...
May 7, 2018: Journal of Biotechnology
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