keyword
MENU ▼
Read by QxMD icon Read
search

siga

keyword
https://www.readbyqxmd.com/read/28527759/selection-of-new-lactic-acid-bacteria-strains-bearing-probiotic-features-from-mucosal-microbiota-of-healthy-calves-looking-for-immunobiotics-through-in-vitro-and-in-vivo-approaches-for-immunoprophylaxis-applications
#1
Sávio Sandes, Luige Alvim, Bruno Silva, Leonardo Acurcio, Cinara Santos, Márcia Campos, Camila Santos, Jacques Nicoli, Elisabeth Neumann, Álvaro Nunes
From the birth, since their mucosal microbiota and immune system are not fully developed, newborn calves are susceptible to several mucosal pathogenic microorganisms. Operating through humoral and non-humoral mechanisms in the host, several lactic acid bacteria strains bearing probiotic features are often employed in livestock as food supplement, improving animal production performance, promoting health and reducing the severity of mucosal infections. Accordingly, we isolated, species-level identified and screened for their probiotic potentials seventy lactic acid bacteria strains from upper airway, vaginal and intestinal mucosa of healthy calves...
July 2017: Microbiological Research
https://www.readbyqxmd.com/read/28525303/low-level-laser-therapy-after-wisdom-teeth-surgery-evaluation-of-immunologic-markers-secretory-immunoglobulin-a-and-lysozyme-levels-and-thermographic-examination-placebo-controlled-study
#2
Tatjana Dostalova, Veronika Kroulikova, Stepan Podzimek, Helena Jelinková
OBJECTIVE: The goal of this investigation is to analyze the effect of therapeutic low-level laser therapy (LLLT) to have a possibility to check pain and inflammation connected with surgical removal of impacted lower third molars in general anesthesia or even phobia [not accompanied by pain or fear of dental treatment, using immunologic markers-secretory immunoglobulin A (sIgA) and lysozyme]. The healing process was also monitored by infrared thermography. BACKGROUND DATA: LLLT can accelerate the proliferation phase of healing and decrease the inflammatory reaction, but the effect is not really clear...
May 16, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28498440/gastrin-induces-multidrug-resistance-via-the-degradation-of-p27kip1-in-the-gastric-carcinoma-cell-line-sgc7901
#3
Kun Zhuang, Lingxia Zhang, Xin Zhang, Hailing Tang, Jun Zhang, Yuan Yan, Kun Han, Hanqing Guo
Multidrug resistance (MDR) is one of the major reasons for the failure of chemotherapy-based gastric carcinoma (GC) treatments, hence, biologically based therapies are urgently needed. Gastrin (GAS), a key gastrointestinal (GI) hormone, was found to be involved in tumor formation, progression, and metastasis. In this study, quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemical staining analysis revealed a high level of expression of GAS in drug-insensitive GC tissues (P<0.01) and similar results were revealed in GC cell lines SGC7901 and its multidrug-resistant variants SGC7901/VCR and SGC7901/ADR...
May 4, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28496443/higher-levels-of-secretory-iga-are-associated-with-low-disease-activity-index-in-patients-with-reactive-arthritis-and-undifferentiated-spondyloarthritis
#4
Fabián Salas-Cuestas, Wilson Bautista-Molano, Juan M Bello-Gualtero, Ivonne Arias, Diana Marcela Castillo, Lorena Chila-Moreno, Rafael Valle-Oñate, Daniel Herrera, Consuelo Romero-Sánchez
INTRODUCTION: Both reactive arthritis (ReA) and undifferentiated spondyloarthritis (uSpA) belong to the group of autoinflammatory diseases called spondyloarthritis (SpA). Hypotheses have been proposed about a relationship between the intestinal mucosa and inflammation of joint tissues. The role of immunoglobulin IgA or secretory immunoglobulin A (SIgA) in the inflammatory and/or clinical activity of patients with SpA remains poorly understood. OBJECTIVE: To evaluate the status of total IgA and SIgA, and the association among the levels of SIgA, IgA, IgA anti-Chlamydia trachomatis, and anti-Shigella spp...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28487998/effects-of-dietary-l-tryptophan-supplementation-on-intestinal-response-to-chronic-unpredictable-stress-in-broilers
#5
Yunshuang Yue, Yuming Guo, Ying Yang
Stress has been recognized as a critical risk factor for gastrointestinal diseases in both humans and animals. However, nutritional strategies to attenuate stress-induced intestinal barrier function and underlying mechanisms remain largely unknown. This study tested the hypothesis that L-tryptophan enhanced intestinal barrier function by regulating mucosal serotonin metabolism in chronic unpredictable stress-exposed broilers. One-day-old male broilers (Arbor Acres) were fed a basal diet supplemented with or without L-tryptophan in the absence or presence of chronic unpredictable stress...
May 9, 2017: Amino Acids
https://www.readbyqxmd.com/read/28487682/a-novel-spiro-heterocyclic-compound-identified-by-the-silkworm-infection-model-inhibits-transcription-in-staphylococcus-aureus
#6
Atmika Paudel, Hiroshi Hamamoto, Suresh Panthee, Keiichi Kaneko, Shigeki Matsunaga, Motomu Kanai, Yutaka Suzuki, Kazuhisa Sekimizu
Synthetic compounds are a vital source of antimicrobial agents. To uncover therapeutically effective antimicrobial agents from a chemical library, we screened over 100,000 synthetic compounds for in vitro antimicrobial activity against methicillin-resistant Staphylococcus aureus and evaluated the in vivo therapeutic effectiveness of the hits in S. aureus-infected silkworms. Three antimicrobial agents exhibited therapeutic effects in the silkworm infection model. One of these, GPI0363, a novel spiro-heterocyclic compound, was bacteriostatic and inhibited RNA synthesis in S...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28487097/systemic-and-mucosal-immune-responses-elicited-by-intranasal-immunization-with-a-pneumococcal-bacterium-like-particle-based-vaccine-displaying-pneumolysin-mutant-plym2
#7
Jingcai Lu, Hongjia Hou, Dandan Wang, Kees Leenhouts, Maarten L van Roosmalen, Tianxu Sun, Tiejun Gu, Yueshuang Song, Chunlai Jiang, Wei Kong, Yongge Wu
Pneumolysin (Ply) is an important virulence factor in pneumococcal infection and a conserved cholesterol-binding cytotoxin expressed by all serotypes of Streptococcus pneumoniae. We previously developed a highly detoxified Ply mutant designated Plym2 by replacement of two amino acids (C428G and W433F), which lost cytotoxicity but retained the ability to induce neutralizing antibodies. In the present work, we applied bacterium-like particles (BLPs) as a carrier and immunostimulant for the development of a Plym2 intranasal vaccine, in which the Plym2 protein was displayed on the surface of BLPs...
May 6, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28484685/vi-capsular-polysaccharide-produced-by-recombinant-salmonella-enterica-serovar-paratyphi-a-confers-immunoprotection-against-infection-by-salmonella-enterica-serovar-typhi
#8
Kun Xiong, Chunyue Zhu, Zhijin Chen, Chunping Zheng, Yong Tan, Xiancai Rao, Yanguang Cong
Enteric fever is predominantly caused by Salmonella enterica serovar Typhi and Salmonella enterica serovar Paratyphi A, and accounts for an annual global incidence of 26.9 millions. In recent years, the rate of S. Paratyphi A infection has progressively increased. Currently licensed vaccines for typhoid fever, live Ty21a vaccine, Vi subunit vaccine, and Vi-conjugate vaccine, confer inadequate cross immunoprotection against enteric fever caused by S. Paratyphi A. Therefore, development of bivalent vaccines against enteric fever is urgently required...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28470626/novel-adjuvant-for-immunization-against-tuberculosis-dna-vaccine-expressing-mycobacterium-tuberculosis-antigen-85a-and-interleukin-15-fusion-product-elicits-strong-immune-responses-in-mice
#9
Li Sun, Quan Yuan, Tianhua Xu, Li Yao, Jiangmin Feng, Jianfei Ma, Lining Wang, Changlong Lv, Danan Wang
OBJECTIVES: To investigate the potential of interleukin (IL)-15 as a novel adjuvant for Mycobacterium tuberculosis (Mtb) antigen 85A (Ag85A) vaccine. RESULTS: C57BL/6 mice were intramuscularly immunized three times with a plasmid expressing the Ag85A-IL-15 fusion protein (pcDNA3.1-Ag85A-IL-15), with the empty pcDNA3.1 vector and the pcDNA3.1-Ag85A as control. Mice vaccinated with pcDNA3.1-Ag85A-IL-15 generated more secretory IgA (sIgA) into their lung (209 ± 21 μg/ml) and acquired an enhanced serum IgG response to Ag85A...
May 3, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/28467021/change-in-oral-health-status-associated-with-menopause-in-japanese-dental-hygienists
#10
N Yoshida, K Sugimoto, S Suzuki, H Kudo
OBJECTIVES: Oral symptoms such as xerostomia and burning mouth syndrome have been recognized to increase associated with menopause. The purpose of this study was to clarify the changes in oral health as well as systemic health due to menopause and their relations with hormonal change and mental status. METHODS: Ninety-seven female dental hygienists aged 40-59 years were assigned to premenopausal, menopausal and post-menopausal groups based on self-reported menstrual condition...
May 3, 2017: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/28466091/yeast-surface-display-of-escherichia-coli-enterotoxin-and-its-effects-of-intestinal-microflora-and-mucosal-immunity
#11
ShiYu Li, Zhou Sha, Xiaoxu Wang, Zhaoyang Bu, Li Wang, Xiaohui Guan, Xulong Lang, Xinglong Wang
Enterotoxigenic Escherichia coli (ETEC) is a significant cause of infectious diarrhea in animals. In this study, yeast surface display technology was employed to investigate the effects of ETEC enterotoxin fusion protein on the intestinal flora and mucosal immunity of rats. ETEC estA, estB, and eltAB (heat-labile and heat-stable toxins) were expressed on the surface of yeast. Rats were divided into normal saline, yeast and display yeast groups. Fecal and jejunal content samples were collected on the 7th, 14th, and 21st days...
May 2, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28464901/chtlr4-pathway-activation-by-astragalus-polysaccharide-in-bursa-of-fabricius
#12
Ruili Zhang, Qun Yu, Guangliang Shi, Rui Liu, Weiqian Zhang, Xia Zhao, Guangxing Li, Ming Ge
BACKGROUND: The Toll-like receptor 4 (TLR4) pathway involves in the pathogen recognition and defense against infection in mammals. Considering that avian and mammalian TLR are differentially mediated, the action of a natural product on avian TLR4 pathway was unclear. High, medium and low doses of Astragalus polysaccharide (APS), were treated the chicken at 7-days-old age by gavage. The sIgA level in the intestinal fluid, the expression of chTLR4 mRNA/protein in bursa of Fabricius as well as the expression of downstream molecules of chTLR4 (chMyD88, chTRIF, chNF-κB, chIRF3, chIFN-β and chTNF-α) were measured on alternate days...
May 2, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28454394/variation-and-significance-of-secretory-immunoglobulin-a-interleukin-6-and-dendritic-cells-in-oral-cancer
#13
Suxin Zhang, Xin Zhang, Ke Yin, Tianke Li, Yang Bao, Zhong Chen
The present study aimed to determine changes in the concentration of secretory immunoglobulin A (SIgA) and interleukin 6 (IL-6) in the saliva of patients with oral cancer, to evaluate the abnormal expression of cluster of differentiation (CD) 1a, CD83, CD80 and CD86 on dendritic cells (DCs) of oral cancer tissues and to discuss the interaction between SIgA, IL-6 and DCs in oral cancer. A total of 40 patients between 27 and 70 years of age, median age 52 years, with primary oral cancer were enrolled in the present study, and a group of 20 healthy male and female volunteers was used as the control group...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28451758/the-evaluation-of-diagnostic-efficiency-for-stromal-herpes-simplex-keratitis-by-the-combination-of-tear-hsv-siga-and-hsv-dna
#14
Jini Qiu, Feifei Huang, Zhujian Wang, Jianjiang Xu, Chaoran Zhang
PURPOSE: To assess the differential diagnostic values for stromal herpes simplex keratitis (HSK) by using tear HSV-sIgA, tear HSV-DNA, and the combination. METHODS: Tear samples for both eyes and the paired serum were collected from 187 stromal HSK and 56 controls. Enzyme-linked immune sorbent assay (ELISA) was used to analyze the tear HSV-sIgA and serum IgG/IgM/IgA. The levels of tear HSV-DNA were measured by polymerase chain reaction (PCR). RESULTS: The positive rates for tear HSV-sIgA and HSV-DNA were 36...
April 27, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28439488/randomized-double-blind-placebo-controlled-parallel-group-study-of-the-effect-of-lactobacillus-paracasei-k71-intake-on-salivary-release-of-secretory-immunoglobulin-a
#15
Yuhi Saito, Mikio Fujii, Toshiyuki Watanabe, Kentaro Maruyama, Yasuyuki Kowatari, Hiromaru Ogata, Takehisa Kumagai
Lactobacillus paracasei K71 was shown to be effective in alleviating the severity of atopic dermatitis in a randomized controlled trial, and a preliminary open-label trial suggested that strain K71 intake enhanced secretory immunoglobulin A (sIgA) release in the saliva. This study investigated the effect of K71 on sIgA release in a randomized, double-blind, placebo-controlled, parallel-group trial. The trial included 62 Japanese subjects aged 20-64 years with relatively low rates of salivary sIgA release. Subjects (n=31 in each group) were randomly given a tablet containing 100 mg (approximately 2 × 10(11) bacteria) of K71 or a placebo tablet daily for 12 weeks...
2017: Bioscience of Microbiota, Food and Health
https://www.readbyqxmd.com/read/28433479/modeling-short-range-substitution-order-and-disorder-in-crystals-application-to-the-ga-si-distribution-in-a-natrolite-zeolite
#16
Sylvian Cadars, Nak Ho Ahn, Kirill Okhotnikov, Jiho Shin, Aurélie Vicente, Suk Bong Hong, Christian Fernandez
Atomic substitutions are a central feature of the physicochemical properties of an increasing number of solid-state materials. The complexity that this chemical disorder locally generates in otherwise crystalline solids poses a major challenge to the understanding of the relationships between the structure and properties of materials at the atomic and molecular level. Strategies designed to efficiently explore the ensemble of local chemical environments present in disordered crystals and predict their signatures in local spectroscopies such as solid-state nuclear magnetic resonance (NMR) are therefore essential...
April 13, 2017: Solid State Nuclear Magnetic Resonance
https://www.readbyqxmd.com/read/28431078/effect-of-threonine-on-secretory-immune-system-using-a-chicken-intestinal-ex%C3%A2-vivo-model-with-lipopolysaccharide-challenge
#17
Q Zhang, X Chen, S D Eicher, K M Ajuwon, T J Applegate
Secretory IgA (sIgA) and its transcytosis receptor, polymeric immunoglobulin receptor (pIgR), along with mucus, form the first lines of intestinal defense. Threonine (Thr) is a major component of intestinal mucins and IgA, which are highly secreted under lipopolysaccharide (LPS) induced inflammation. In the current study, the effect of Thr on the secretory immune system was determined in an ex vivo chicken ileal explant model. Results showed that a 2-hour Thr-deprivation of culture medium induced a compensatory increase in the mRNA expression of interleukin-8 (IL-8), mucin 2 ( ), and IgA during LPS challenge, and this increase was suppressed with Thr addition to the media ( P  ≤ 0...
April 18, 2017: Poultry Science
https://www.readbyqxmd.com/read/28419912/the-mucosal-pellicle-an-underestimated-factor-in-oral-physiology
#18
REVIEW
Christian Hannig, Matthias Hannig, Anna Kensche, Guy Carpenter
Bioadhesion and bio-adsorption of proteins, glycoproteins and other biomolecules are ubiquitous phenomena in the oral cavity. While the protective role of the adsorbed salivary biomolecules on teeth (the acquired enamel pellicle) is well established, it has yet to be defined whether comparable processes occur on the desquamating oral soft tissues. The general term for these layers is pellicle, but due to the different characteristics of the coated surfaces the enamel pellicle and mucosal pellicle are their own entities...
April 8, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28416898/siga-response-and-incidence-of-upper-respiratory-tract-infections-during-intensified-training-in-youth-basketball-players
#19
H Moraes, M S Aoki, C G Freitas, Afs Arruda, G Drago, A Moreira
The aim of the present study was to examine the effect of an intensified training phase followed by a tapering phase on the salivary immunoglobulin A concentration and on the upper respiratory tract infection (URTI) symptoms in young male basketball players. The session rating of perceived exertion method was used to quantify the internal training load, and the Wisconsin Upper Respiratory Symptom Survey-21 questionnaire was used to assess URTI symptoms. The Yo-Yo IR1 test and saliva collection were carried out at the beginning of the study (T1), after the intensified phase (T2), and after tapering (T3)...
March 2017: Biology of Sport
https://www.readbyqxmd.com/read/28407432/diagnosis-of-biofilm-infections-in-cystic-fibrosis-patients
#20
REVIEW
Niels Høiby, Thomas Bjarnsholt, Claus Moser, Peter Østrup Jensen, Mette Kolpen, Tavs Qvist, Kasper Aanaes, Tanja Pressler, Marianne Skov, Oana Ciofu
Chronic Pseudomonas aeruginosa biofilm lung infection in cystic fibrosis patients is the best described biofilm infection in medicine. The initial focus can be the paranasal sinuses and then follows repeated colonization and infection of the lungs by aspiration. The matrix of the biofilms is dominated by alginate and the pathogenesis of tissue damage is immune complex-mediated chronic inflammation dominated by polymorphonuclear leukocytes and their products (DNA, oxygen radicals and proteases). The P. aeruginosa biofilm infection can be diagnosed by microscopy of lung tissue, sputum and mucus from the paranasal sinuses, where aggregates of the bacteria are found surrounded by the abundant alginate matrix...
April 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
keyword
keyword
80930
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"