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https://www.readbyqxmd.com/read/28801574/intestinal-transepithelial-permeability-of-oxytocin-into-the-blood-is-dependent-on-the-receptor-for-advanced-glycation-end-products-in-mice
#1
Haruhiro Higashida, Kazumi Furuhara, Agnes-Mikiko Yamauchi, Kisaburo Deguchi, Ai Harashima, Seiichi Munesue, Olga Lopatina, Maria Gerasimenko, Alla B Salmina, Jia-Sheng Zhang, Hikari Kodama, Hironori Kuroda, Chiharu Tsuji, Satoshi Suto, Hiroshi Yamamoto, Yasuhiko Yamamoto
Plasma oxytocin (OT) originates from secretion from the pituitary gland into the circulation and from absorption of OT in mother's milk into the blood via intestinal permeability. However, the molecular mechanism underlying the absorption of OT remains unclear. Here, we report that plasma OT concentrations increased within 10 min after oral delivery in postnatal day 1-7 mice. However, in Receptors for Advanced Glycation End Products (RAGE) knockout mice after postnatal day 3, an identical OT increase was not observed...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28800162/feeding-imprinting-the-extreme-test-case-of-premature-infants-born-with-very-low-birth-weight
#2
Moriya Suberi, Iris Morag, Tzipora Strauss, Ronny Geva
Feeding imprinting, considered a survival-enabling process, is not well understood. Infants born very preterm, who first feed passively, are an effective model for studying feeding imprinting. Retrospective analysis of neonatal intensive care unit (NICU) records of 255 infants (Mgestational age  = 29.98 ± 1.64) enabled exploring the notion that direct breastfeeding (DBF) during NICU stay leads to consumption of more mother's milk and earlier NICU discharge. Results showed that DBF before the first bottle feeding is related to shorter transition into oral feeding, a younger age of full oral feeding accomplishment and earlier discharge...
August 11, 2017: Child Development
https://www.readbyqxmd.com/read/28799014/breakfast-habits-dairy-product-consumption-physical-activity-and-their-associations-with-body-mass-index-in-children-aged-6-18
#3
Tugba Koca, Mustafa Akcam, Filiz Serdaroglu, Selim Dereci
The purpose of this study was to determine breakfast habits, dairy product consumption, and physical activity and their relations with body mass index (BMI) in schoolchildren and adolescents. This cross-sectional, school-based study was performed with children aged 6-18 years. Height and weight were measured, and a BMI z-score was calculated for each child. Breakfast consumption frequency, intake of milk and other dairy products, physical activity habits, and mothers' employment status were assessed via a self-report questionnaire...
August 11, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28798374/culture-independent-assessment-of-human-milk-microbial-community-in-lactational-mastitis
#4
Shriram H Patel, Yati H Vaidya, Reena J Patel, Ramesh J Pandit, Chaitanya G Joshi, Anju P Kunjadiya
Breastfeeding undoubtedly provides important benefits to the mother-infant dyad and should be encouraged. Mastitis, one of the common but major cause of premature weaning among lactating women, is an inflammation of connective tissue within the mammary gland. This study reports the influence of mastitis on human milk microbiota by utilizing 16 S rRNA gene sequencing approach. We sampled and sequenced microbiome from 50 human milk samples, including 16 subacute mastitis (SAM), 16 acute mastitis (AM) and 18 healthy-controls...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28795377/comparison-of-the-fatty-acid-profile-of-spanish-infant-formulas-and-galician-women-breast-milk
#5
Rocío Barreiro, Patricia Regal, Olga López-Racamonde, Alberto Cepeda, Cristina A Fente
The importance of dietary lipids during childhood is evident, as they are necessary for correct growth and development of the newborn. When breastfeeding is not possible, infant formulas are designed to mimic human milk as much as possible to fulfill infant's requirements. However, the composition of these dairy products is relatively constant, while human milk is not a uniform bio-fluid and changes according to the requirements of the baby. In this study, breast milk samples were donated by 24 Spanish mothers in different lactation stages and different infant formulas were purchased in supermarkets and pharmacies...
August 9, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28794439/maternal-low-intensity-physical-exercise-prevents-obesity-in-offspring-rats-exposed-to-early-overnutrition
#6
Tatiane Aparecida Ribeiro, Laize Peron Tófolo, Isabela Peixoto Martins, Audrei Pavanello, Júlio Cezar de Oliveira, Kelly Valério Prates, Rosiane Aparecida Miranda, Claudinéia Conationi da Silva Franco, Rodrigo Mello Gomes, Flávio Andrade Francisco, Vander Silva Alves, Douglas Lopes de Almeida, Veridiana Mota Moreira, Kesia Palma-Rigo, Elaine Vieira, Gabriel Sergio Fabricio, Marcos Ricardo da Silva Rodrigues, Wilson Rinaldi, Ananda Malta, Paulo Cezar de Freitas Mathias
Low intensity exercise during pregnancy and lactation may create a protective effect against the development of obesity in offspring exposed to overnutrition in early life. To test these hypotheses, pregnant rats were randomly assigned into 2 groups: Sedentary and Exercised, low intensity, on a rodent treadmill at 30% VO2Max /30-minute/session/3x/week throughout pregnancy and the lactation. Male offspring were raised in small litters (SL, 3 pups/dam) and normal litters (NL, 9 pups/dam) as models of early overnutrition and normal feed, respectively...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28791778/redox-properties-of-transitional-milk-from-mothers-of-preterm-infants
#7
Simeon Minić, Miloš Ješić, Dijana Đurović, Srdjan Miletić, Nikoleta Lugonja, Vesna Marinković, Aleksandra Nikolić-Kokić, Snežana Spasić, Miroslav M Vrvić
AIM: There is a discrepancy between the amount of transitional milk produced by mothers of preterm infants and the low capacity of premature infants to consume it. This milk can be used in milk banks, but previous studies found that there are large variations in the level of host-defence proteins in individual samples of milk from mothers of premature infants, which implies that large individual variations in antioxidative defence composition are also possible. METHODS: Milk samples were collected from 20 healthy mothers of preterm infants...
August 9, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28789730/iodine-status-of-postpartum-women-and-their-infants-in-australia-after-the-introduction-of-mandatory-iodine-fortification
#8
Dao Huynh, Dominique Condo, Robert Gibson, Beverly Muhlhausler, Philip Ryan, Sheila Skeaff, Maria Makrides, Shao J Zhou
Mandatory I fortification in bread was introduced in Australia in 2009 in response to the re-emergence of biochemical I deficiency based on median urinary I concentration (UIC)<100 µg/l. Data on the I status of lactating mothers and their infants in Australia are scarce. The primary aim of this study was to assess the I status, determined by UIC and breast milk I concentration (BMIC), of breast-feeding mothers in South Australia and UIC of their infants. The secondary aim was to assess the relationship between the I status of mothers and their infants...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28789728/circadian-feeding-patterns-of-12-month-old-infants
#9
Poh Hui Wee, See Ling Loy, Jia Ying Toh, Elaine Kwang Hsia Tham, Yin Bun Cheung, Keith M Godfrey, Peter D Gluckman, Seang Mei Saw, Yap-Seng Chong, Ngee Lek, Jerry Kok Yen Chan, Daniel Yam Thiam Goh, Mary Foong-Fong Chong, Fabian Yap
Early life nutrition and feeding practices are important modifiable determinants of subsequent obesity, yet little is known about the circadian feeding pattern of 12-month-old infants. We aimed to describe the 24-h feeding patterns of 12-month-old infants and examine their associations with maternal and infant characteristics. Mothers from a prospective birth cohort study (n 431) reported dietary intakes of their 12-month-old infants and respective feeding times using 24-h dietary recall. Based on their feeding times, infants were classified into post-midnight (00...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28783445/donor-milk-or-formula-a-qualitative-study-of-postpartum-mothers-of-healthy-newborns
#10
Laura R Kair, Valerie J Flaherman
BACKGROUND: Many breastfed infants receive supplemental feeds during the birth hospitalization, either by maternal request or due to medical indications. Donor milk from a certified milk bank has become increasingly available and is now used in some settings for term and late preterm infants. No studies have explored maternal opinions about donor milk and formula as options for supplementary feedings. Research aim: This study aimed to explore maternal perceptions about donor milk and formula supplementation and implications for continued breastfeeding...
July 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28783113/-omics-in-human-colostrum-and-mature-milk-looking-to-old-data-with-new-eyes
#11
REVIEW
Flaminia Bardanzellu, Vassilios Fanos, Alessandra Reali
Human Milk (HM) is the best source for newborn nutrition until at least six months; it exerts anti-inflammatory and anti-infective functions, promotes immune system formation and supports organ development. Breastfeeding could also protect from obesity, diabetes and cardiovascular disease. Furthermore, human colostrum (HC) presents a peculiar role in newborn support as a protective effect against allergic and chronic diseases, in addition to long-term metabolic benefits. In this review, we discuss the recent literature regarding "omics" technologies and growth factors (GF) in HC and the effects of pasteurization on its composition...
August 7, 2017: Nutrients
https://www.readbyqxmd.com/read/28780499/how-to-feed-a-baby-recovering-from-necrotising-enterocolitis-when-maternal-milk-is-not-available
#12
REVIEW
Nicholas D Embleton, Stefan P Zalewski
Necrotising enterocolitis (NEC) is a devastating disease with significant mortality and serious adverse outcomes in at least 50% including short gut and poor neurodevelopment. Research and management are complicated by a lack of robust clinical markers, and without histological confirmation, there is a risk of both underdiagnosis and overdiagnosis. Interunit variations in the thresholds for surgical referral, laparotomy and postmortem rates mean the actual incidence is difficult to determine, especially because the histological term 'NEC' is used in practice to describe a heterogeneous clinical syndrome...
August 5, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28777356/health-effects-of-carotenoids-during-pregnancy-and-lactation
#13
REVIEW
Monika A Zielińska, Aleksandra Wesołowska, Beata Pawlus, Jadwiga Hamułka
Adequate nutrition is particularly important during pregnancy since it is needed not only for maintaining the health of the mother, but also determines the course of pregnancy and its outcome, fetus development as well as the child's health after birth and during the later period of life. Data coming from epidemiological and interventions studies support the observation that carotenoids intake provide positive health effects in adults and the elderly population. These health effects are the result of their antioxidant and anti-inflammatory properties...
August 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28772152/long-term-time-trends-in-human-intake-of-pops-in-the-czech-republic-indicate-a-need-for-continuous-monitoring
#14
Katarína Bányiová, Milena Černá, Ondřej Mikeš, Klára Komprdová, Anežka Sharma, Tenzing Gyalpo, Pavel Čupr, Martin Scheringer
Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) from the group of persistent organic pollutants are detected in human tissues years or even decades after their ban. Exposure to PCBs and OCPs can pose risks to human health. In the present study, we calculated the daily intakes of PCBs and OCPs in the Czech population and investigated the long-term trends of human exposure to POPs. Data on POP concentrations from a 16-year period of breast-milk monitoring were used. A toxicokinetic model with consideration of compound-specific elimination half-lives was used to calculate the mothers' daily intake of PCBs and OCPs representing the intake of POPs by all exposure routes...
July 31, 2017: Environment International
https://www.readbyqxmd.com/read/28760422/with-antitransglutaminase-antibodies-in-the-breast-milk-is-breastfeeding-beneficial-or-harmful
#15
Fabiana Zingone, Salvatore Scotto di Santolo, Luigi Cinquanta, Carolina Ciacci
Breast milk is fundamental to induce an appropriate immunotolerance in the newborn. Here, we present the case of a young mother who was diagnosed with celiac disease while breastfeeding. She is dealing with the problem of knowing that celiac disease-specific autoantibodies are present in her breast milk, but not knowing if they are potentially harmful to her baby.
September 2017: Nutrition
https://www.readbyqxmd.com/read/28760341/biological-effects-of-anti-rankl-antibody-administration-in-pregnant-mice-and-their-newborns
#16
Nobuaki Okamatsu, Nobuhiro Sakai, Akiko Karakawa, Naoka Kouyama, Yurie Sato, Katsunori Inagaki, Yuji Kiuchi, Katsuji Oguchi, Takako Negishi-Koga, Masamichi Takami
Denosumab, a fully human monoclonal antibody that neutralizes receptor activator of nuclear factor-κB ligand (RANKL) and blocks osteoclast differentiation, has received approval in Japan for use as an anti-resorptive drug for osteoporosis and skeletal-related events (SREs) in patients with solid cancer. Denosumab is contraindicated during pregnancy, though the effects of blocking RANKL activity on pregnant mothers and their newborns are unclear. We used mice to investigate the effects of an anti-RANKL antibody on maternal and newborn health...
July 29, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28752645/effect-of-pumping-pressure-on-onset-of-lactation-after-caesarean-section-a-randomized-controlled-study
#17
Feng Zhang, Yahui Yang, Ting Bai, Lele Sun, Mingzhu Sun, Xueling Shi, Meng Zhu, Meijuan Ge, Haiou Xia
Caesarean section is associated with weaker newborn suction pressure. This nonblinded, randomized trial explored the effect of suction pressures generating by a breast pump on mothers' onset of lactation and milk supply after caesarean section. A high pressure group (-150 mmHg), a low pressure group (-100 mmHg), and a control group (none) were generated under computer random assignment with concealed allocation in 2 tertiary hospitals. The breast pumping began within 2 hr after caesarean operation (6 times a day and 30 min per time) until onset of lactation...
July 27, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28750427/environmental-risk-factors-for-type-1-diabetes-mellitus-development
#18
Boljat Antonela, Gunjača Ivana, Konstantinović Ivan, Vidan Nikolina, Boraska Perica Vesna, Pehlić Marina, Škrabić Veselin, Zemunik Tatijana
Background Although environmental factors induce development of type 1 diabetes mellitus (T1DM) in genetically susceptible individuals, many of those factors have been uncovered. Therefore, the aim of the present study was to analyze associations of T1DM with a wide range of environmental factors. Material and Methods A case-control study was conducted on 249 diabetic and 255 healthy individuals from the Dalmatian region of South Croatia. Data regarding risk factors during pregnancy and early life period of the child were evaluated...
July 27, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28749825/a-fortified-donor-milk-policy-is-associated-with-improved-in-hospital-head-growth-and-weight-gain-in-very-low-birth-weight-infants
#19
Gemma Ginovart, Ignasi Gich, Antonio Gutiérrez, Sergio Verd
BACKGROUND: Previous research has reported that infants fed donor milk grow slower than those fed formula. However, most of the trials used unfortified donor milk, which limits the ability to generalize the results to current clinical practice. PURPOSE: To evaluate the impact of early human milk feeding (donor milk and/or mother's own milk) with standard fortification on in-hospital growth of very low-birth-weight infants. METHODS: This pre-/postretrospective study included selected newborn infants less than 1500 g admitted to a level IV neonatal intensive care unit before and after the introduction of a policy providing donor milk when mother's own milk was not available in sufficient quantity to meet her infant's need...
August 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28748061/host-molecular-factors-and-viral-genotypes-in-the-mother-to-child-hiv-1-transmission-in-sub-saharan-africa
#20
REVIEW
Linda Chapdeleine M Mouafo, Béatrice Dambaya, Nicole N Ngoufack, Céline N Nkenfou
Maternal viral load and immune status, timing and route of delivery, viral subtype, and host genetics are known to influence the transmission, acquisition and disease progression of human immunodeficiency virus-1 (HIV-1) infection. This review summarizes the findings from published works on host molecular factors and virus genotypes affecting mother to child transmission (MTCT) in Africa and identifies the gaps that need to be addressed in future research. Articles in PubMed, Google and AIDSearch and relevant conference abstracts publications were searched...
June 23, 2017: Journal of Public Health in Africa
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