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https://www.readbyqxmd.com/read/27912038/high-levels-of-chemokine-c-c-motif-ligand-20-in-human-milk-and-its-production-by-oral-keratinocytes
#1
Alan G Lourenço, Marilena C Komesu, Geraldo Duarte, Luiz A Del Ciampo, Marisa M Mussi-Pinhata, Aparecida Y Yamamoto
BACKGROUND: Chemokine C-C motif ligand 20 (CCL20) is implicated in the formation and function of mucosal lymphoid tissues. Although CCL20 is secreted by many normal human tissues, no studies have evaluated the presence of CCL20 in human milk or its production by oral keratinocytes stimulated by human milk. OBJECTIVE: To evaluate the presence of CCL20 in breast milk and verify CCL20 secretion in vitro by oral keratinocytes stimulated with human and bovine milk, as well as its possible association with breast milk lactoferrin levels...
December 2, 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/27909996/modelling-the-cost-effectiveness-of-human-milk-and-breastfeeding-in-preterm-infants-in-the-united-kingdom
#2
James Mahon, Lindsay Claxton, Hannah Wood
OBJECTIVES: To estimate the cost savings and health benefits in the UK NHS that could be achieved if human milk usage in the NICU was increased. METHODS: A systematic review established the disease areas with the strong sources of evidence of the short, medium and long-term benefits of human milk for preterm infants as opposed to the use of formula milk. The analysis assessed the economic impact of reducing rates of necrotising enterocolitis, sepsis, sudden infant death syndrome, leukaemia, otitis media, obesity and neurodevelopmental impairment...
December 2016: Health Economics Review
https://www.readbyqxmd.com/read/27906557/barriers-to-human-milk-feeding-at-discharge-of-very-low-birth-weight-infants-maternal-goal-setting-as-a-key-social-factor
#3
Erin Fleurant, Michael Schoeny, Rebecca Hoban, Ifeyinwa V Asiodu, Brittany Riley, Paula P Meier, Harold Bigger, Aloka L Patel
BACKGROUND: While black mothers initiate human milk (HM) provision at lower rates than non-black mothers in the United States, some neonatal intensive care units (NICUs) report similar initiation rates regardless of race/ethnicity for mothers of very-low-birth-weight (VLBW) infants. However, racial disparity frequently becomes evident in the proportion of black infants who continue to receive HM feedings at NICU discharge. Since social factors have been associated with differences in HM provision for term infants, we sought to identify differences in social factors associated with HM feeding at discharge based on race/ethnicity...
December 1, 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/27904644/ambient-temperature-affects-postnatal-litter-size-reduction-in-golden-hamsters
#4
Sarah A Ohrnberger, Raquel Monclús, Heiko G Rödel, Teresa G Valencak
BACKGROUND: To better understand how different ambient temperatures during lactation affect survival of young, we studied patterns of losses of pups in golden hamsters (Mesocricetus auratus) at different ambient temperatures in the laboratory, mimicking temperature conditions in natural habitats. Golden hamsters produce large litters of more than 10 young but are also known to wean fewer pups at the end of lactation than they give birth to. We wanted to know whether temperature affects litter size reductions and whether the underlying causes of pup loss were related to maternal food (gross energy) intake and reproductive performance, such as litter growth...
2016: Frontiers in Zoology
https://www.readbyqxmd.com/read/27903517/branched-chain-fatty-acid-composition-of-human-milk-and-the-impact-of-maternal-diet-the-global-exploration-of-human-milk-gehm-study
#5
Kelly A Dingess, Christina J Valentine, Nicholas J Ollberding, Barbara S Davidson, Jessica G Woo, Suzanne Summer, Yongmei M Peng, M Lourdes Guerrero, Guillermo M Ruiz-Palacios, Rinat R Ran-Ressler, Robert J McMahon, J Thomas Brenna, Ardythe L Morrow
BACKGROUND: An understudied component of the diet, branched-chain fatty acids (BCFAs) are distinctive saturated fatty acids that may have an important influence on health. Human-milk fatty acid composition is known to differ worldwide, but comparative data are lacking on BCFAs. OBJECTIVE: We tested the hypotheses that concentrations of BCFAs in human milk differ between populations and are associated with maternal diet. DESIGN: We surveyed the BCFA composition of samples collected as part of a standardized, prospective study of human-milk composition...
November 30, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27903233/evaluation-of-structure-chaperone-activity-and-allergenicity-of-reduced-glycated-adduct-of-bovine-%C3%AE-casein
#6
Reza Yousefi, Leila Ferdowsi, Zohreh Tavaf, Tanaz Sadeghian, Ali Mohammad Tamaddon, Mozhgan Moghtaderi, Zahra Pourpak
Milk has a potent reducing environment with an important quantity of sugar levels. In the current study β-casein was glycated in the presence of D-glucose and sodium cyanoborohydride as a reducing agent. Then, the reduced glucitol adduct of β-casein was used for the structural and functional analyses using different spectroscopic techniques. The results of fluorescence and far ultraviolet circular dichroism assessments suggest important structural alteration upon non-enzymatic glycation of β-casein. In addition, the chaperone activity, micellization properties and antioxidant activity of this protein were altered upon glucose modification...
November 21, 2016: Protein and Peptide Letters
https://www.readbyqxmd.com/read/27902504/a-password-protected-web-site-for-mothers-expressing-milk-for-their-preterm-infants
#7
MaryAnn Blatz, Donna Dowling, Patricia W Underwood, Amy Bieda, Gregory Graham
BACKGROUND: Research has demonstrated that breast milk significantly decreases morbidities that impact length of stay for preterm infants, but there is a need to test interventions to improve breastfeeding outcomes. Since many Americans are using technologies such as the Intranet and smartphones to find health information and manage health, a Web site was developed for mothers who provide breast milk for their preterm hospitalized infants. PURPOSE: This study examined the efficacy of a Web site for mothers to educate them about breast milk expression and assist them in monitoring their breast milk supply...
November 29, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27901335/the-role-of-natural-galactagogues-during-breast-feeding-focus-on-a-galega-officinalis-based-food-supplement
#8
Silvia Salatino, Luca Giacomelli, Ilaria Carnevali, Erika Giacomelli
Maternal milk is the optimal food for newborns. To this end, a number of interventions are used to enhance milk production. However, pharmacological interventions may be associated with a perceived risk of adverse effects and therefore many mothers prefer to rely on natural herbal remedies. Several herbal remedies have been traditionally used to this purpose. However, the level of evidence supporting their use is mixed. Among different currently-employed natural remedies, Galega officinalis has emerged to be one of those sustained by the strongest evidence...
November 30, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27900667/should-domperidone-be-used-as-a-galactagogue-possible-safety-implications-for-mother-and-child
#9
Luc M Hondeghem, Noël H Logghe
Domperidone has been used as a galactagogue; however, solid evidence from an adequate sized randomized clinical trial is missing. Optimal dosage, start of treatment, length of treatment and scope of patients who can benefit also remain unknown. Although milk obtained after domperidone administration has not been shown to have untoward effects on newborns, no sufficiently large randomized clinical trial has been done to establish safety. Domperidone has repeatedly been shown to produce sudden cardiac death, starting at 30 mg/day...
November 29, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27898903/intestinal-lactose-and-mineral-concentration-affect-the-microbial-ecophysiology-along-the-gastrointestinal-tract-of-formula-fed-neonatal-piglets
#10
R Pieper, W Vahjen, J Zentek
Hyperprolificacy in modern pig breeds has led to increased use of artificial rearing and formula feeding of neonatal piglets, which may change their intestinal bacterial ecophysiology. Here, newborn piglets ( = 8 per group) were fed a bovine milk-based formula (FO) or allowed to suckle their mothers (sow milk [SM]) for 2 wk, and digesta samples from the stomach, jejunum, and colon were subsequently analyzed for enzyme activities, bacterial metabolites, and 16S rRNA transcripts of bacterial groups by quantitative real-time PCR...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27897979/breastmilk-production-in-the-first-4-weeks-after-birth-of-term-infants
#11
Jacqueline C Kent, Hazel Gardner, Donna T Geddes
Breastmilk provides the ideal nutrition for the infant, and exclusive breastfeeding is recommended for the first 6 months. Adequate milk production by the mother is therefore critical, and early milk production has been shown to significantly affect milk production during established lactation. Previous studies indicate that milk production should reach the lower limit of normal for established lactation (440 mL per day) by day 11 after birth. We have used test-weighing of term infants before and after each breastfeed over 24 h to measure milk production in the first 4 weeks of lactation in mothers with and without perceived breastfeeding problems to provide information on how often milk production is inadequate...
November 25, 2016: Nutrients
https://www.readbyqxmd.com/read/27891832/cortisol-in-human-milk-predicts-child-bmi
#12
Jennifer Hahn-Holbrook, Tran Bao Le, Anna Chung, Elysia Poggi Davis, Laura M Glynn
OBJECTIVE: Breastfeeding has been linked to lower rates of childhood obesity. Human milk contains cortisol, known to regulate glucose storage and metabolism. The aim of this study was to to test the hypothesis that early exposure to cortisol in human breast milk helps to modulate infant body mass index (BMI) trajectories over the first 2 years of life. METHODS: Growth curve modeling was used to examine whether infant exposure to cortisol in human milk at 3 months predicted changes in child body mass index percentile (BMIP) at 6, 12, and 24 months of age in 51 breastfeeding mother-child pairs...
December 2016: Obesity
https://www.readbyqxmd.com/read/27890414/developmental-neurotoxicants-in-human-milk-comparison-of-levels-and-intakes-in-three-european-countries
#13
Eliška Čechová, Martin Scheringer, Marta Seifertová, Ondřej Mikeš, Kristýna Kroupová, Jan Kuta, Joan Forns, Merete Eggesbø, Ilona Quaak, Marijke de Cock, Margot van de Bor, Henrieta Patayová, Ľubica Palkovičová Murínová, Anton Kočan
Developmental neurotoxicants (DNTs), such as methylmercury (MeHg), polychlorinated biphenyls (PCBs) and selected organochlorine pesticides (OCPs), have gained increasing interest recently due to their possible relation to developmental disorders in children, which are increasing worldwide. We analyzed levels of 14 developmental neurotoxicants in human milk samples from Slovakia (n=37), the Netherlands (n=120) and Norway (n=388). Positive identification for most target analytes was >95% in all samples. In all three countries MeHg was measured for the first time in mother milk...
November 24, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27889334/leukocytes-in-expressed-breast-milk-of-asthmatic-mothers
#14
D-L Dixon, K D Forsyth
OBJECTIVE: Infants are born immunologically immature. However, breastfeeding mothers retain an immunological link to their infants. While it is generally accepted that infants are at an immunological advantage when compared with formula-fed infants, the benefit of long-term exclusive breastfeeding by atopic mothers remains controversial. Inconsistency in the conferral of benefit may be due to differences in the immunological constituents passed to the recipient infant. The aim of this investigation was to examine the profile of human milk cells and cytokines from asthmatic compared to non-asthmatic mothers...
November 23, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27888022/intentions-and-barriers-toward-breastfeeding-among-jordanian-mothers-a-cross-sectional-descriptive-study-using-quantitative-method
#15
Ahmad Yahya Al-Sagarat, Ghada Yaghmour, Lorna Moxham
PROBLEM/BACKGROUND: Breastfeeding is very important for both mother and infant. Within Jordanian hospitals, intentions and barriers to breastfeeding have not been addressed effectively during preparing policies in routine antenatal care or in maternal and child health care. AIM: To identify the intentions and barriers toward breastfeeding among Jordanian mothers with a specific focus on women from low income circumstances. METHODS: A cross-sectional descriptive study using quantitative methods was adopted in this study...
November 22, 2016: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/27883236/long-term-reduction-in-food-allergy-susceptibility-in-mice-by-combining-breastfeeding-induced-tolerance-and-tgf-%C3%AE-enriched-formula-after-weaning
#16
Akila Rekima, Patricia Macchiaverni, Mathilde Turfkruyer, Sebastien Holvoet, Lénaïck Dupuis, Nour Baiz, Isabella Annesi-Maesano, Annick Mercenier, Sophie Nutten, Valérie Verhasselt
BACKGROUND: Oral tolerance induction in early life is a promising approach for food allergy prevention. Its success requires the identification of factors necessary for its persistence. OBJECTIVES: We aimed to assess in mice duration of allergy prevention by breastfeeding-induced oral tolerance and whether oral TGF-β supplementation after weaning would prolong it. METHODS: We quantified ovalbumin (OVA) and OVA specific immunoglobulins levels by ELISA in milk from the EDEN birth cohort...
November 24, 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27881729/brazilian-immigrant-mothers-beliefs-and-practices-related-to-infant-feeding-a-qualitative-study
#17
Ana Cristina Lindsay, Sherrie F Wallington, Mary L Greaney, Maria Helena Hasselman, Marcia Maria Tavares Machado, Raquel S Mezzavilla
BACKGROUND: Exclusive breastfeeding for the first 6 months of life and timely introduction of appropriate solid foods are important determinants of weight status in infancy and later life stages. Disparities in obesity rates among young children suggest that maternal feeding practices during the first 2 years of life may contribute to these disparities. Brazilians are a growing immigrant group in the United States, yet little research has focused on parental beliefs and behaviors affecting the health of Brazilian immigrant children in the United States...
November 23, 2016: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/27876761/early-infant-adipose-deposition-is-positively-associated-with-the-n-6-to-n-3-fatty-acid-ratio-in-human-milk-independent-of-maternal-bmi
#18
M C Rudolph, B E Young, D J Lemas, C E Palmer, T L Hernandez, L A Barbour, J E Friedman, N F Krebs, P S MacLean
BACKGROUND/OBJECTIVES: Excessive infant weight gain in the first 6-months of life is a powerful predictor of childhood obesity and related health risks. In mice, omega-6 fatty acids (FA) serve as potent ligands driving adipogenesis during early development. The ratio of omega-6 relative to omega-3 (n-6/n-3) FA in human milk (HM) has increased 3-fold over the last 30 years, but the impact of this shift on infant adipose development remains undetermined. This study investigated how maternal obesity and maternal dietary FA (as reflected in maternal red blood cells (RBC) composition) influenced HM n-6 and n-3 FAs, and whether the HM n-6/n-3 ratio was associated with changes in infant adipose deposition between 2-weeks and 4-months postpartum...
November 23, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27875035/mothers-experience-of-not-breastfeeding-in-a-breastfeeding-culture
#19
Ingjerd Hvatum, Kari Glavin
AIM AND OBJECTIVES: To describe women's experience of not breastfeeding in a breastfeeding culture. BACKGROUND: Breastfeeding represents a fundamental cultural value in Norway and many other countries, and a mother may often have intense emotions about breastfeeding her child. Political and health authorities in many countries have given high priority to encouraging breastfeeding among mothers. However, breastfeeding can be challenging and sometimes affects mothers' mental health and the joy of interaction...
November 22, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27871690/the-relation-between-breast-milk-sodium-to-potassium-ratio-and-maternal-report-of-a-milk-supply-concern
#20
Masahiko Murase, Erin A Wagner, Caroline J Chantry, Kathryn G Dewey, Laurie A Nommsen-Rivers
We report that, among exclusively breastfeeding mothers at day 7 postpartum, those with milk supply concerns were significantly more likely to exhibit biochemical evidence of less progress toward mature lactation (elevated ratio of breast milk sodium to potassium concentration). Furthermore, an elevated ratio of breast milk sodium to potassium concentration was predictive of early weaning.
November 18, 2016: Journal of Pediatrics
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