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McGill model

Rita L McGill, Robin Ruthazer, Eduardo Lacson, Klemens B Meyer, Dana C Miskulin, Daniel E Weiner
Introduction Central venous catheters (CVC) increase risks associated with hemodialysis (HD), but may be necessary until an arteriovenous fistula (AVF) or graft (AVG) is achieved. The impact of vascular imaging on achievement of working AVF and AVG has not been firmly established. Methods Retrospective cohort of patients initiating HD with CVC in 2010-2011, classified by exposure to venography or Doppler vein mapping, and followed through December 31, 2012. Standard and time-dependent Cox models were used to determine hazard ratios (HRs) of death, working AVF, and any AVF or AVG...
November 20, 2016: Hemodialysis International
Ryan J McGill, Stefan C Dombrowski
The present study examined the factor structure of the Wide Range Assessment of Memory and Learning-Second Edition (WRAML2) core battery with participants from the normative sample aged 9 to 90 years (n = 880) using higher order exploratory and confirmatory factor analytic techniques that were not reported in the in the WRAML2 Administration and Technical Manual Exploratory factor analysis results suggested only one factor, whereas confirmatory factor analysis results favored the three factors posited by the test authors...
November 19, 2016: Assessment
Mark Vellend, Maria Dornelas, Lander Baeten, Robin Beauséjour, Carissa D Brown, Pieter De Frenne, Sarah C Elmendorf, Nicholas J Gotelli, Faye Moyes, Isla H Myers-Smith, Anne E Magurran, Brian J McGill, Hideyasu Shimadzu, Caya Sievers
We present new data and analyses revealing fundamental flaws in a critique of two recent meta-analyses of local-scale temporal biodiversity change. First, the conclusion that short-term time series lead to biased estimates of long-term change was based on two errors in the simulations used to support it. Second, the conclusion of negative relationships between temporal biodiversity change and study duration was entirely dependent on unrealistic model assumptions, the use of a subset of data, and inclusion of one outlier data point in one study...
November 19, 2016: Ecology
Francesca Adler-Baeder, Chelsea Garneau, Brian Vaughn, Julianne McGill, Kate Taylor Harcourt, Scott Ketring, Thomas Smith
Although suggestions are that benefits of relationship and marriage education (RME) participation extend from the interparental relationship with parenting and child outcomes, few evaluation studies of RME test these assumptions and the relationship among changes in these areas. This quasi-experimental study focuses on a parallel process growth model that tests a spillover hypothesis of program effects and finds, in a sample of low-income minority mothers with a child attending a Head Start program, that increases in mother reports of coparenting agreement for RME participants predict decreases in their reports of punitive parenting behaviors...
November 14, 2016: Family Process
Michaël Maes, Mitchell R McGill, Tereza Cristina da Silva, Chloé Abels, Margitta Lebofsky, James L Weemhoff, Taynã Tiburcio, Isabel Veloso Alves Pereira, Joost Willebrords, Sara Crespo Yanguas, Anwar Farhood, Alain Beschin, Jo A Van Ginderachter, Silvia Penuela, Hartmut Jaeschke, Bruno Cogliati, Mathieu Vinken
Pannexins constitute a relatively new family of transmembrane proteins that form channels linking the cytoplasmic compartment with the extracellular environment. The presence of pannexin1 in the liver has been documented previously, where it underlies inflammatory responses, such as those occurring upon ischemia-reperfusion injury. In the present study, we investigated whether pannexin1 plays a role in acute drug-induced liver toxicity. Hepatic expression of pannexin1 was characterized in a mouse model of acetaminophen-induced hepatotoxicity...
November 8, 2016: Archives of Toxicology
Woung-Ru Tang, Chen-Yi Kao
OBJECTIVE: The spiritual well-being of terminally ill cancer patients is an important indicator of the quality of their lives and of the quality of hospice care, but no validated tools are available for assessing this indicator in Taiwan. METHOD: The present cross-sectional study validated the Spiritual Well-Being Scale-Mandarin version (SWBS-M) by testing its psychometric properties in 243 cancer patients from five teaching hospitals throughout Taiwan. Construct validity was tested by factor analysis and hypothesis testing...
November 4, 2016: Palliative & Supportive Care
Brian C Callaghan, Rong Xia, Evan Reynolds, Mousumi Banerjee, Amy E Rothberg, Charles F Burant, Emily Villegas-Umana, Rodica Pop-Busui, Eva L Feldman
Importance: Past studies have shown an association between metabolic syndrome and polyneuropathy, but the precise components that drive this association remain unclear. Objectives: To determine the prevalence of polyneuropathy stratified by glycemic status in well-characterized obese and lean participants and investigate the association of specific components of metabolic syndrome with polyneuropathy. Design, Setting, and Participants: We performed a cross-sectional, observational study from November 1, 2010, to December 31, 2014, in obese participants (body mass index [calculated as weight in kilograms divided by height in meters squared] of 35 or more with no comorbid conditions or 32 or more with at least 1 comorbid condition) from a weight management program and lean controls from a research website...
October 31, 2016: JAMA Neurology
Toby Dylan Hocking, Patricia Goerner-Potvin, Andreanne Morin, Xiaojian Shao, Tomi Pastinen, Guillaume Bourque
MOTIVATION: Many peak detection algorithms have been proposed for ChIP-seq data analysis, but it is not obvious which algorithm and what parameters are optimal for any given data set. In contrast, regions with and without obvious peaks can be easily labeled by visual inspection of aligned read counts in a genome browser. We propose a supervised machine learning approach for ChIP-seq data analysis, using labels that encode qualitative judgments about which genomic regions contain or do not contain peaks...
October 24, 2016: Bioinformatics
N Kriek, J G Groeneweg, D L Stronks, D de Ridder, F J P M Huygen
BACKGROUND: Conventional tonic spinal cord stimulation (SCS) is an effective treatment for patients with therapy-resistant complex regional pain syndrome (CRPS). Although the therapeutic effect of SCS can diminish over time due to tolerance, pain control can be regained by changing the pulse width and the amplitude and/or by increasing the stimulation frequency. This multicentre, double-blind, randomized and placebo-controlled crossover trial was conducted to investigate whether more effective pain reduction is achieved with different frequencies (trial registration, current controlled trials, ISRCTN 36655259)...
October 7, 2016: European Journal of Pain: EJP
Corine M Visscher, Erin A van Wesemael-Suijkerbuijk, Frank Lobbezoo
The aim of this study was to explore the association between the presence of comorbidities and the pain experience in individual patients with temporomandibular disorder (TMD). This clinical trial comprised 112 patients with TMD pain. For all participants the presence of the following comorbid factors was assessed: pain in the neck; somatization; impaired sleep; and depression. Pain experience was evaluated using the McGill Pain Questionnaire (MPQ). For each subject the TMD-pain experience was assessed for three dimensions - sensory, affective, and evaluative - as specified in the MPQ...
October 2016: European Journal of Oral Sciences
Blythe J O'Hara, Joanne Gale, Bronwyn McGill, Adrian Bauman, Lana Hebden, Margaret Allman-Farinelli, Michelle Maxwell, Philayrath Phongsavan
PURPOSE: This study investigated whether participants in a 6-month telephone-based coaching program, who set physical activity, nutrition, and weight loss goals had better outcomes in these domains. DESIGN: Quasi-experimental design. SETTING: The Australian Get Healthy Information and Coaching Service (GHS), a free population-wide telephone health-coaching service that includes goal setting as a key component of its coaching program. PARTICIPANTS: Consenting GHS coaching participants who had completed coaching between February 2009 and December 2012 (n = 4108)...
August 2, 2016: American Journal of Health Promotion: AJHP
Errikos A Koen, Petros D Antonarakos, Labrini T Katranitsa, Kostas E Poulis, Thomas M Apostolou, Evangelos A Christodoulou, Anastasios G Christodoulou
STUDY DESIGN: We followed a longitudinal observational design with 2 assessment points, presurgery and postsurgery, in 83 consecutive patients undergoing single-level lumbar discectomy. OBJECTIVE: Prognostic data can be gathered from commonly used generic outcome measures to identify patients at risk of persistent leg pain-associated chronicity, following lumbar discectomy SUMMARY OF BACKGROUND DATA:: Suboptimal results observed, following open lumbar discectomy, have been connected to the interplay among presurgery pain characteristics, functional and psychosocial adaptations like persistent pain, disability, and depression...
July 19, 2016: Clinical Spine Surgery
Andrew E Lincoln, Gerard A Gioia, Shireen Atabaki, Michael Yochelson, Elizabeth Delasobera, Catherine McGill, Maegan Sady, Jessica Clark, Justin Cooper, Ethan Urbansky
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Wilma M Hopman, Elizabeth G Vandenkerkhof, Meg E Carley, Margaret B Harrison
AIMS: To identify factors associated with longitudinal changes in health-related quality of life in community-dwelling individuals with venous or mixed-venous leg ulcers. BACKGROUND: Most care focuses primarily on healing; this research may additionally lead to strategies to improve quality of life. DESIGN: Data from four studies (2000-2009) were combined (2012) to examine quality of life in community-dwelling individuals referred for care of chronic leg wounds...
June 27, 2016: Journal of Advanced Nursing
M P Vélez, T E Arbuckle, P Monnier, W D Fraser
STUDY QUESTION: Is the female 2th- to 4th-finger ratio (2D:4D) associated with fecundity as measured by time-to-pregnancy (TTP)? SUMMARY ANSWER: Our study does not support an association between female 2D:4D and TTP. WHAT IS KNOWN ALREADY: The 2th- to 4th-finger ratio (2D:4D) has been proposed as a potential indicator of greater androgen exposure during fetal development. Women exposed in utero to unbalanced steroid hormones may have impaired fecundity in the adulthood...
September 2016: Human Reproduction
Rita L McGill, Robin Ruthazer, Klemens B Meyer, Dana C Miskulin, Daniel E Weiner
BACKGROUND AND OBJECTIVES: Use of peripherally inserted central catheters has expanded rapidly, but the consequences for patients who eventually require hemodialysis are undefined. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Our national, population-based analysis included 33,918 adult Medicare beneficiaries from the US Renal Data System who initiated hemodialysis with central venous catheters as their sole vascular access in 2010 and 2011. We used linked Medicare claims to identify peripherally inserted central catheter exposures and evaluate the associations of peripherally inserted central catheter placement with transition to working arteriovenous fistulas or grafts and patient survival using a Cox model with time-dependent variables...
August 8, 2016: Clinical Journal of the American Society of Nephrology: CJASN
Maja Johannsen, Maja O'Connor, Mia Skytte O'Toole, Anders Bonde Jensen, Inger Højris, Robert Zachariae
PURPOSE: To assess the efficacy of mindfulness-based cognitive therapy (MBCT) for late post-treatment pain in women treated for primary breast cancer. METHODS: A randomized wait list-controlled trial was conducted with 129 women treated for breast cancer reporting post-treatment pain (score ≥ 3 on pain intensity or pain burden assessed with 10-point numeric rating scales). Participants were randomly assigned to a manualized 8-week MBCT program or a wait-list control group...
October 1, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
K Rysava, R A R McGill, J Matthiopoulos, J G C Hopcraft
RATIONALE: Nutritional bottlenecks often limit the abundance of animal populations and alter individual behaviours; however, establishing animal condition over extended periods of time using non-invasive techniques has been a major limitation in population ecology. We test if the sequential measurement of δ(15) N values in a continually growing tissue, such as hair, can be used as a natural bio-logger akin to tree rings or ice cores to provide insights into nutritional stress. METHODS: Nitrogen stable isotope ratios were measured by continuous-flow isotope-ratio mass spectrometry (IRMS) from 20 sequential segments along the tail hairs of 15 migratory wildebeest...
July 15, 2016: Rapid Communications in Mass Spectrometry: RCM
Stefan C Dombrowski, Ryan J McGill, Gary L Canivez
Exploratory and confirmatory factor analytic studies were not reported in the Technical Manual for the Woodcock-Johnson, 4th ed. Cognitive (WJ IV Cognitive; Schrank, McGrew, & Mather, 2014b) Instead, the internal structure of the WJ IV Cognitive was extrapolated from analyses based on the full WJ IV test battery (Schrank, McGrew, & Mather, 2014b). Even if the veracity of extrapolating from the WJ IV full battery were accepted, there were shortcomings in the choices of analyses used and only limited information regarding those analyses was presented in the WJ IV Technical Manual (McGrew, Laforte, & Shrank, 2014)...
June 9, 2016: Psychological Assessment
Suhail A R Doi, Luis Furuya-Kanamori, Jessica M Engel, Mohammad H Jamal, Rachel V Stankowski, Jeffrey Barkun, Adedayo A Onitilo
PURPOSE: The McGill Brisbane Symptom Score (MBSS) is a clinical score for pancreatic cancer patients upon initial presentation that takes into account four variables (weight loss, abdominal pain, jaundice, and history of smoking) to stratify them into two MBSS intensity categories. Several studies have suggested that these categories are strongly associated with eventual survival in patients with resectable (rPCa) and unresectable (uPCa) pancreatic cancer. This study aimed to validate the MBSS in a cohort of patients with pancreatic cancer from a single institution...
July 2016: Cancer Causes & Control: CCC
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