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McGill model

N Kriek, J G Groeneweg, D L Stronks, D de Ridder, F J P M Huygen
BACKGROUND: Conventional tonic spinal cord stimulation (SCS) is an effective treatment for patients with therapy-resistant complex regional pain syndrome (CRPS). Although the therapeutic effect of SCS can diminish over time due to tolerance, pain control can be regained by changing the pulse width and the amplitude and/or by increasing the stimulation frequency. This multicentre, double-blind, randomized and placebo-controlled crossover trial was conducted to investigate whether more effective pain reduction is achieved with different frequencies (trial registration, current controlled trials, ISRCTN 36655259)...
October 7, 2016: European Journal of Pain: EJP
Corine M Visscher, Erin A van Wesemael-Suijkerbuijk, Frank Lobbezoo
The aim of this study was to explore the association between the presence of comorbidities and the pain experience in individual patients with temporomandibular disorder (TMD). This clinical trial comprised 112 patients with TMD pain. For all participants the presence of the following comorbid factors was assessed: pain in the neck; somatization; impaired sleep; and depression. Pain experience was evaluated using the McGill Pain Questionnaire (MPQ). For each subject the TMD-pain experience was assessed for three dimensions - sensory, affective, and evaluative - as specified in the MPQ...
October 2016: European Journal of Oral Sciences
Blythe J O'Hara, Joanne Gale, Bronwyn McGill, Adrian Bauman, Lana Hebden, Margaret Allman-Farinelli, Michelle Maxwell, Philayrath Phongsavan
PURPOSE: This study investigated whether participants in a 6-month telephone-based coaching program, who set physical activity, nutrition, and weight loss goals had better outcomes in these domains. DESIGN: Quasi-experimental design. SETTING: The Australian Get Healthy Information and Coaching Service (GHS), a free population-wide telephone health-coaching service that includes goal setting as a key component of its coaching program. PARTICIPANTS: Consenting GHS coaching participants who had completed coaching between February 2009 and December 2012 (n = 4108)...
August 2, 2016: American Journal of Health Promotion: AJHP
Errikos A Koen, Petros D Antonarakos, Labrini T Katranitsa, Kostas E Poulis, Thomas M Apostolou, Evangelos A Christodoulou, Anastasios G Christodoulou
STUDY DESIGN: We followed a longitudinal observational design with 2 assessment points, presurgery and postsurgery, in 83 consecutive patients undergoing single-level lumbar discectomy. OBJECTIVE: Prognostic data can be gathered from commonly used generic outcome measures to identify patients at risk of persistent leg pain-associated chronicity, following lumbar discectomy SUMMARY OF BACKGROUND DATA:: Suboptimal results observed, following open lumbar discectomy, have been connected to the interplay among presurgery pain characteristics, functional and psychosocial adaptations like persistent pain, disability, and depression...
July 19, 2016: Clinical Spine Surgery
Andrew E Lincoln, Gerard A Gioia, Shireen Atabaki, Michael Yochelson, Elizabeth Delasobera, Catherine McGill, Maegan Sady, Jessica Clark, Justin Cooper, Ethan Urbansky
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Wilma M Hopman, Elizabeth G Vandenkerkhof, Meg E Carley, Margaret B Harrison
AIMS: To identify factors associated with longitudinal changes in health-related quality of life in community-dwelling individuals with venous or mixed-venous leg ulcers. BACKGROUND: Most care focuses primarily on healing; this research may additionally lead to strategies to improve quality of life. DESIGN: Data from four studies (2000-2009) were combined (2012) to examine quality of life in community-dwelling individuals referred for care of chronic leg wounds...
June 27, 2016: Journal of Advanced Nursing
M P Vélez, T E Arbuckle, P Monnier, W D Fraser
STUDY QUESTION: Is the female 2th- to 4th-finger ratio (2D:4D) associated with fecundity as measured by time-to-pregnancy (TTP)? SUMMARY ANSWER: Our study does not support an association between female 2D:4D and TTP. WHAT IS KNOWN ALREADY: The 2th- to 4th-finger ratio (2D:4D) has been proposed as a potential indicator of greater androgen exposure during fetal development. Women exposed in utero to unbalanced steroid hormones may have impaired fecundity in the adulthood...
September 2016: Human Reproduction
Rita L McGill, Robin Ruthazer, Klemens B Meyer, Dana C Miskulin, Daniel E Weiner
BACKGROUND AND OBJECTIVES: Use of peripherally inserted central catheters has expanded rapidly, but the consequences for patients who eventually require hemodialysis are undefined. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Our national, population-based analysis included 33,918 adult Medicare beneficiaries from the US Renal Data System who initiated hemodialysis with central venous catheters as their sole vascular access in 2010 and 2011. We used linked Medicare claims to identify peripherally inserted central catheter exposures and evaluate the associations of peripherally inserted central catheter placement with transition to working arteriovenous fistulas or grafts and patient survival using a Cox model with time-dependent variables...
August 8, 2016: Clinical Journal of the American Society of Nephrology: CJASN
Maja Johannsen, Maja O'Connor, Mia Skytte O'Toole, Anders Bonde Jensen, Inger Højris, Robert Zachariae
PURPOSE: To assess the efficacy of mindfulness-based cognitive therapy (MBCT) for late post-treatment pain in women treated for primary breast cancer. METHODS: A randomized wait list-controlled trial was conducted with 129 women treated for breast cancer reporting post-treatment pain (score ≥ 3 on pain intensity or pain burden assessed with 10-point numeric rating scales). Participants were randomly assigned to a manualized 8-week MBCT program or a wait-list control group...
October 1, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
K Rysava, R A R McGill, J Matthiopoulos, J G C Hopcraft
RATIONALE: Nutritional bottlenecks often limit the abundance of animal populations and alter individual behaviours; however, establishing animal condition over extended periods of time using non-invasive techniques has been a major limitation in population ecology. We test if the sequential measurement of δ(15) N values in a continually growing tissue, such as hair, can be used as a natural bio-logger akin to tree rings or ice cores to provide insights into nutritional stress. METHODS: Nitrogen stable isotope ratios were measured by continuous-flow isotope-ratio mass spectrometry (IRMS) from 20 sequential segments along the tail hairs of 15 migratory wildebeest...
July 15, 2016: Rapid Communications in Mass Spectrometry: RCM
Stefan C Dombrowski, Ryan J McGill, Gary L Canivez
Exploratory and confirmatory factor analytic studies were not reported in the Technical Manual for the Woodcock-Johnson, 4th ed. Cognitive (WJ IV Cognitive; Schrank, McGrew, & Mather, 2014b) Instead, the internal structure of the WJ IV Cognitive was extrapolated from analyses based on the full WJ IV test battery (Schrank, McGrew, & Mather, 2014b). Even if the veracity of extrapolating from the WJ IV full battery were accepted, there were shortcomings in the choices of analyses used and only limited information regarding those analyses was presented in the WJ IV Technical Manual (McGrew, Laforte, & Shrank, 2014)...
June 9, 2016: Psychological Assessment
Suhail A R Doi, Luis Furuya-Kanamori, Jessica M Engel, Mohammad H Jamal, Rachel V Stankowski, Jeffrey Barkun, Adedayo A Onitilo
PURPOSE: The McGill Brisbane Symptom Score (MBSS) is a clinical score for pancreatic cancer patients upon initial presentation that takes into account four variables (weight loss, abdominal pain, jaundice, and history of smoking) to stratify them into two MBSS intensity categories. Several studies have suggested that these categories are strongly associated with eventual survival in patients with resectable (rPCa) and unresectable (uPCa) pancreatic cancer. This study aimed to validate the MBSS in a cohort of patients with pancreatic cancer from a single institution...
July 2016: Cancer Causes & Control: CCC
Virginia M Boquiren, Thomas F Hack, Roanne L Thomas, Anna Towers, Winkle B Kwan, Andrea Tilley, Elizabeth Quinlan, Baukje Miedema
Arm morbidity (AM) arising from breast cancer (BC) treatment can detrimentally impact quality of life; often limiting a survivor's ability to participate in valued activities. The present study explored (a) the developmental time course of AM [restricted range of motion (ROM), pain, and arm volume changes], negative affect, and perceived disability in the immediate years post-surgery, and (b) the mediating role of perceived disability on the relationship between AM and negative affect over time. In this 5-year longitudinal study, BC survivors from four Canadian oncology clinics (n = 431) completed five annual clinical assessments, where differences in ROM (shoulder abduction, external rotation) and arm volume between the affected and non-affected arm were measured...
June 2016: Breast Cancer Research and Treatment
Katherine M McKendy, Nancy Posel, David M Fleiszer, Melina C Vassiliou
OBJECTIVE: To determine the feasibility and effectiveness of a learner-created virtual patient (VP) curriculum for postgraduate year 2 surgical residents. DESIGN: Using a social-constructivist model of learning, we designed a learner-created VP curriculum to help postgraduate year 2 residents prepare for their in-training surgical examination. Each resident was assigned to create a VP curriculum based on the learning objectives for this examination, and VP cases were then disseminated to all residents for completion...
July 2016: Journal of Surgical Education
Malvina Klag, Marie-Claire Richer
This paper describes the emergence of an "information brokerage" in the project management office of the McGill University Health Centre (MUHC) in Montreal. This process evolved during unprecedented transformation linked to a redevelopment project. Information brokering became a core function in the MUHC's context of major change. To develop an information brokering model, the paper draws upon the literature on knowledge brokering, applies Daft and Lengel's (1986) seminal framework on information processing in organizations, and builds on the MUHC experience...
2016: Healthcare Quarterly
Karen A Willoughby, Charo Rodríguez, Miriam Boillat, Marion Dove, Peter Nugus, Yvonne Steinert, Leonora Lalla
BACKGROUND: Despite the implementation of longitudinal community-based pre-clerkship courses in several Canadian medical schools, there is a paucity of data assessing students' views regarding their experiences. The present study sought to measure students' perceived effects of the new Longitudinal Family Medicine Experience (LFME) course at McGill University. METHODS: A 34-item questionnaire called the 'LFME Survey (Student Version)' was created, and all first-year medical students completed it online...
May 2016: Education for Primary Care
Katie V Turner, Bryan M Moreton, David A Walsh, Nadina B Lincoln
PURPOSE: To examine the fit between data from the Short Form McGill Pain Questionnaire (SF-MPQ-2) and the Rasch model, and to explore the reliability and internal responsiveness of measures of pain in people with knee osteoarthritis. METHODS: Participants with knee osteoarthritis completed the SF-MPQ-2, Intermittent and Constant Osteoarthritis Pain questionnaire (ICOAP) and painDETECT. Participants were sent the same questionnaires 3 and 6 months later. RESULTS: Fit to the Rasch model was not achieved for the SF-MPQ-2 Total scale...
March 30, 2016: Disability and Rehabilitation
J Y Rosner, M Gupta, M McGill, X Xue, P K Chatterjee, M Yoshida-Hay, W Robeson, C N Metz
OBJECTIVE: Maternal magnesium (Mg) deficiency has been associated with fetal growth restriction. Using a mouse model of maternal Mg deficiency-induced fetal growth restriction, we sought to investigate the effect of Mg deficiency on placental physiology and function. METHODS: In vivo: Pregnant Swiss Webster mice were fed either 100% of the recommended amount of Mg (control) or 10%Mg (Mg-deficient) (8 per group). Dams were euthanized on gestational day 17 and placentas were collected, weighed and assessed for Mg concentrations, as well as nutrient transporter mRNA expression...
March 2016: Placenta
Samantha Hajna, Nancy A Ross, Lawrence Joseph, Sam Harper, Kaberi Dasgupta
INTRODUCTION: There is evidence that greater neighbourhood walkability (i.e., neighbourhoods with more amenities and well-connected streets) is associated with higher levels of total walking in Europe and in Asia, but it remains unclear if this association holds in the Canadian context and in chronic disease populations. We examined the relationships of different walkability measures to biosensor-assessed total walking (i.e., steps/day) in adults with type 2 diabetes living in Montreal (QC, Canada)...
2016: PloS One
Mitchell R McGill, Stefanie Kennon-McGill, Dianne Durham, Hartmut Jaeschke
CONTEXT: Although the liver is the primary target organ in acetaminophen (APAP) toxicity, other organs are affected. Previous data suggested that chronic APAP abuse can be ototoxic and the mechanism involves APAP-induced oxidative stress and reactive metabolite (N-acetyl-p-benzoquinone imine, NAPQI)-induced endoplasmic reticulum stress. However, the effect of a single acute overdose on hearing has not been tested. OBJECTIVES: To determine if a single acute APAP overdose causes hearing damage, and to explore possible mechanisms of APAP ototoxicity...
February 2016: Toxicology Mechanisms and Methods
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