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https://www.readbyqxmd.com/read/28331629/congenital-diaphragmatic-hernia-a-review
#1
REVIEW
Praveen Kumar Chandrasekharan, Munmun Rawat, Rajeshwari Madappa, David H Rothstein, Satyan Lakshminrusimha
Congenital Diaphragmatic hernia (CDH) is a condition characterized by a defect in the diaphragm leading to protrusion of abdominal contents into the thoracic cavity interfering with normal development of the lungs. The defect may range from a small aperture in the posterior muscle rim to complete absence of diaphragm. The pathophysiology of CDH is a combination of lung hypoplasia and immaturity associated with persistent pulmonary hypertension of newborn (PPHN) and cardiac dysfunction. Prenatal assessment of lung to head ratio (LHR) and position of the liver by ultrasound are used to diagnose and predict outcomes...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28330440/prevalence-and-predictors-of-intra-abdominal-hypertension-and-compartment-syndrome-in-surgical-patients-in-critical-care-units-at-kenyatta-national-hospital
#2
A Muturi, P Ndaguatha, Daniel Ojuka, A Kibet
BACKGROUND: Intra-abdominal hypertension (IAH) affects almost every organ sytem.If it is not detected early and corrected, mortality would be high. The prevalence of IAH and abdominal compartment syndrome (ACS) at Kenyatta National Hospital (KNH) critical care units is not known. The aim of this sudy was to determine the prevalence and factors associated with development of IAH/ACS among critically ill surgical patients. METHODS: This was a cross sectional descriptive study involving surgical patients in critical care units at KNH, carried out from March 2015 to October 2015...
March 23, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28327105/association-of-physical-activity-on-body-composition-cardiometabolic-risk-factors-and-prevalence-of-cardiovascular-disease-in-the-korean-population-from-the-fifth-korea-national-health-and-nutrition-examination-survey-2008-2011
#3
Gwang-Sil Kim, Eui Im, Ji-Hyuck Rhee
BACKGROUND: Data regarding associations among physical activity (PA) level, body composition, and prevalence of cardiovascular diseases in Asian populations are rare. METHODS: The International Physical Activity Questionnaire (IPAQ) was utilized to estimate PA levels and analyze the association of PA level with various body composition parameters and the prevalence of cardiovascular diseases by using data from the Korean National Health and Nutrition Examination Survey from 2008 to 2011...
March 21, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28322173/thyroid-hormones-metabolic-syndrome-and-its-components
#4
Alessandro P Delitala, Giuseppe Fanciulli, Giovanni M Pes, Margherita Maioli, Giuseppe Delitala
Metabolic syndrome is a clustering of various metabolic parameters, which included diabetes, low high-density lipoprotein cholesterol, elevated triglycerides, abdominal obesity, and hypertension. It has merged as a worldwide epidemic and a major public health care concern. However, due to the different criteria used for the assessment, the frequency of metabolic syndrome in the general population is variable but it more common in the older people. Metabolic syndrome is closely linked to cardiovascular risk and increases cardiovascular outcomes and all-cause mortality...
March 20, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28322017/elevated-high-sensitivity-c-reactive-protein-increases-the-risk-of-microalbuminuria-in-subjects-with-cardiovascular-disease-risk-factors
#5
Shi-Kun Yang, Jun Liu, Bin Yi, Juan Mao, Xian-Ming Zhang, Yan Liu, Dan-Dan Lei, Ming Gui, Hao Zhang
Microalbuminuria is an early biomarker of kidney injury, the aim of this study was to investigate the impact of high sensitivity C-reactive protein (hs-CRP) on microalbuminuria in adults with cardiovascular disease (CVD) risk factors. A total of 5667 subjects who voluntarily attended annual health screenings in the Third Xiangya Hospital of Central South University were included in the study. Logistic regression was used to determine the validity of hs-CRP to predict the presence of microalbuminuria. In the unadjusted regression analysis, male gender (OR 2...
March 20, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28321802/sepsis-risk-factors-in-infants-with-congenital-diaphragmatic-hernia
#6
Michaël Levy, Nolwenn Le Sache, Mostafa Mokhtari, Guy Fagherazzi, Gaelle Cuzon, Benjamin Bueno, Virginie Fouquet, Alexandra Benachi, Sergio Eleni Dit Trolli, Pierre Tissieres
BACKGROUND: Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly and remains among the most challenging ICU-managed disease. Beside severe pulmonary hypertension, lung hypoplasia and major abdominal surgery, infective complications remain major determinants of outcome. However, the specific incidence of sepsis as well as associated risk factors is unknown. METHODS: This prospective, 4-year observational study took place in the pediatric intensive care and neonatal medicine department of the Paris South University Hospitals (Le Kremlin-Bicêtre, France), CDH national referral center and involved 62 neonates with CDH...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28316855/central-nervous-system-involvement-in-henoch-schonlein-purpura-in-children-and-adolescents
#7
Iliyana H Pacheva, Ivan S Ivanov, Krastina Stefanova, Elena Chepisheva, Lyubov Chochkova, Dafina Grozeva, Angelina Stoyanova, Stojan Milenkov, Penka Stefanova, Anna Petrova
Central nervous system (CNS) involvement in Henoch-Schonlein purpura (HSP) is rare but poses diagnostic difficulties. The aim of the study was to establish the frequency of CNS involvement in HSP, to analyze its clinical characteristics and do a literature review. Medical files of patients with HSP admitted at the Department of Pediatrics, Plovdiv, were studied retrospectively for a five-year period (2009-2013). Diagnosis was based on the American College of Rheumatology criteria. Out of 112 children with HSP 1 case (0...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28302476/the-protective-effects-of-diabetes-mellitus-on-post-evar-aaa-growth-and-reinterventions
#8
Chien Yi M Png, Rami O Tadros, Ming Kang, William E Beckerman, Melissa L Tardiff, Ageliki G Vouyouka, Michael L Marin, Peter L Faries
INTRODUCTION AND OBJECTIVE: This study aims to investigate the effect of diabetes on post-endovascular aneurysm repairs (EVAR) of abdominal aortic aneurysms (AAA). METHODS: 1479 consecutive patients who underwent AAA EVAR were reviewed. The cohorts were divided based on their diabetes status and compared. Preoperative demographic and comorbidity data were analyzed using t-test and Chi-squared test while post-EVAR outcomes were analyzed using Probit multivariate model, followed by Kaplan Meier survival curve and Cox regression...
March 13, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28298537/obesity-mediates-the-association-between-mediterranean-diet-consumption-and-insulin-resistance-and-inflammation-in-us-adults
#9
Yong-Moon Park, Jiajia Zhang, Susan E Steck, Teresa T Fung, Linda J Hazlett, Kyungdo Han, Seung-Hyun Ko, Anwar T Merchant
Background: The inverse association between Mediterranean diet (Med-diet) consumption and insulin resistance or inflammatory markers is well known. However, the extent to which obesity may act directly on or mediate this association is unclear.Objective: We aimed to investigate whether the associations between Med-diet consumption and markers of insulin resistance and inflammation are mediated by body mass index (BMI) or waist circumference (WC) in a representative US population.Methods: We used cross-sectional data from 4700 adults aged 20-90 y without any previous diagnosis of cancer, cardiovascular disease, diabetes, or hypertension based on the NHANES III, 1988-1994...
March 15, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28298219/sedentary-behaviours-during-pregnancy-a-systematic-review
#10
Caterina Fazzi, David H Saunders, Kathryn Linton, Jane E Norman, Rebecca M Reynolds
BACKGROUND: In the general population, at least 50% of time awake is spent in sedentary behaviours. Sedentary behaviours are activities that expend less energy than 1.5 metabolic equivalents, such as sitting. The amount of time spent in sedentary behaviours is a risk factor for diseases such as type 2 diabetes, cardiovascular disease, and death from all causes. Even individuals meeting physical activity guidelines are at a higher risk of premature death and adverse metabolic outcomes if they sit for extended intervals...
March 16, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28287603/shunt-surgery-right-heart-catheterization-and-vascular-morphometry-in-a-rat-model-for-flow-induced-pulmonary-arterial-hypertension
#11
Diederik E van der Feen, Michel Weij, Annemieke Smit-van Oosten, Lysanne M Jorna, Quint A J Hagdorn, Beatrijs Bartelds, Rolf M F Berger
In this protocol, PAH is induced by combining a 60 mg/kg monocrotalin (MCT) injection with increased pulmonary blood flow through an aorto-caval shunt (MCT+Flow). The shunt is created by inserting an 18-G needle from the abdominal aorta into the adjacent caval vein. Increased pulmonary flow has been demonstrated as an essential trigger for a severe form of PAH with distinct phases of disease progression, characterized by early medial hypertrophy followed by neointimal lesions and the progressive occlusion of the small pulmonary vessels...
February 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28285957/comparison-of-renal-outcomes-in-patients-treated-by-zenith-%C3%A2-fenestrated-and-zenith-%C3%A2-abdominal-aortic-aneurysm-stent-grafts-in-us-prospective-pivotal-trials
#12
L R de Souza, G S Oderich, M A Farber, S Haulon, P V Banga, A H Pereira, P Gloviczki, S C Textor, F Jia
OBJECTIVE/BACKGROUND: Fenestrated endovascular repair (FEVAR) has been used to treat complex abdominal aortic aneurysms (AAAs). The risk of renal function deterioration compared with infrarenal endovascular aortic repair (EVAR) has not been determined. METHODS: Patients with preserved renal function (estimated glomerular filtration rate [eGFR] > 45 mL/minute) enrolled in two prospective, non-randomised studies evaluating Zenith fenestrated and AAA stent grafts were matched (1:2) by propensity scores for age, sex, hypertension, diabetes, and pre-operative eGFR...
March 10, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28285309/elevated-serum-uric-acid-level-predicts-rapid-decline-in-kidney-function
#13
Masanari Kuwabara, Petter Bjornstad, Ichiro Hisatome, Koichiro Niwa, Carlos A Roncal-Jimenez, Ana Andres-Hernando, Thomas Jensen, Tamara Milagres, Yuka Sato, Gabriela Garcia, Minoru Ohno, Miguel A Lanaspa, Richard J Johnson
BACKGROUND: While elevated serum uric acid level (SUA) is a recognized risk factor for chronic kidney disease, it remains unclear whether change in SUA is independently associated with change in estimated glomerular filtration rate (eGFR) over time. Accordingly, we examined the longitudinal associations between change in SUA and change in eGFR over 5 years in a general Japanese population. METHODS: This was a large, single-center, retrospective 5-year cohort study at St...
March 11, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28285211/ovarian-serous-cystadenoma-with-ectopic-adrenal-tissue-in-a-65-year-old-patient-a-case-report
#14
Çağdaş Şahin, Enes Taylan, Ali Akdemir, Osman Zekioglu, Parvane Seyidova, Ahmet Mete Ergenoglu
INTRODUCTION: Ectopic adrenal tissue is a very rare entity in adult females, especially in the ovary, and is generally diagnosed incidentally during surgery. Although it can present at various sites during childhood, it becomes atrophic by adulthood due to normally functioning adrenal glands. Patients are predominantly asymptomatic; however, in some cases endocrine symptoms such as hypertension and fasciotruncal obesity due to hormonal activity can be seen or neoplastic transformation can appear...
February 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28285092/visceral-to-subcutaneous-fat-ratio-is-independently-related-to-small-and-large-cerebrovascular-lesions-even-in-healthy-subjects
#15
Satoshi Higuchi, Yusuke Kabeya, Kiyoe Kato
BACKGROUND AND AIMS: The severity of obesity is evaluated by visceral-to-subcutaneous fat ratio (VS ratio), which may be useful for predicting atherosclerosis. However, it is unclear how VS ratio affects different types of cerebrovascular lesions. This study was conducted to evaluate the clinical impact of visceral fat accumulation on the cerebrovascular lesions. METHODS: This cross-sectional study included 980 apparently healthy Japanese adults who underwent a health check-up program focused toward atherosclerosis, between 2011 and 2014...
March 2, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28283270/relationship-between-diffuse-idiopathic-skeletal-hyperostosis-abdominal-aortic-calcification-and-associated-metabolic-disorders-data-from-the-camargo-cohort
#16
Emilio Pariente-Rodrigo, Giusi Alessia Sgaramella, José Manuel Olmos-Martínez, Stefanie Francesca Pini-Valdivieso, Rosa Landeras-Alvaro, José Luis Hernández-Hernández
BACKGROUND AND OBJECTIVE: Diffuse idiopathic skeletal hyperostosis (DISH) and abdominal aortic calcification (AAC) are related to an increased cardiovascular risk. The aim of this study was to analyse a possible relationship between both entities and also the association between metabolic disorders and DISH. PATIENTS AND METHOD: Analytic cross-sectional study in a population-based cohort. DISH (with Resnick-Niwayama criteria) and AAC (with AAC-24 scale) were assessed on plain x-ray images...
March 7, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28282819/management-of-mixed-type-congenital-mesoblastic-nephroma-case-series-and-review-of-the-literature
#17
J Daniel, A Ruzic, J Dalland, V Miller, M Hanna
Congenital mesoblastic nephroma (CMN) is the most common renal tumor of infancy; however, it occurs infrequently with an incidence of 1 : 125,000. The cellular and classical variants are the most common subtypes of tumors, with a mixed variant occurring infrequently. We describe two cases of mixed variant CMN, which presented within days of each other differing in their clinical behavior. The first case followed a typical course, previously described in the literature, while the other deviated significantly...
March 4, 2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28282682/-angioneurotic-edema-as-a-differential-diagnosis-of%C3%A2-recurrent-abdominal-pain
#18
Claudia Schadow, Cora Wex, Christian Wybranski, Thomas Kalinski, Christian Schulz, Frank Meyer
History and admission findings A 46-year-old woman was admitted because of recurrent postprandial vomiting including weight loss of 30 kg within the last 5 - 6 months. The physical investigation was indicative of preileus. Investigations CT scan revealed an unclear thickening of the jejunum. Treatment and course Explorative laparotomy was performed because of the considerable degree of suffering and a tendency of worsening. Intraoperatively, the preoperatively observed thickening was confirmed at 3 subsequent segments of the jejunum (3 cm long each) prompting to segmental resection of the jejunum...
March 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28282605/variations-of-renal-tissue-oxygenation-during-abdominal-compartment-syndrome-and-sepsis
#19
Stavros Kalfadis, Vaia Nalbanti, Orestis Ioannidis, George Porfiriou, Dimitrios Botsios, Konstantinos Tsalis
PURPOSE: This experimental study was designed to evaluate the renal tissue oxygenation under the coexistence of abdominal compartment syndrome and sepsis. MATERIAL AND METHODS: Fourteen non-breed dogs were divided into two groups: the control group (8) and the study group (6). Sepsis was established with intravenous endotoxin infusion at 100μg/kg for over 30min. Insufflation of CO2 in the peritoneal cavity was used for the increase in intra-abdominal pressure (IAP)...
March 7, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28282272/role-of-serum-soluble-cd163-in-the-diagnosis-risk-of-bleeding-and-prognosis-of-gastro-esophageal-varices-in-cirrhotic-patients
#20
Rabab Fouad, Iman Hamza, Marwa Khairy, Marwa Elsharkawy, Amal A Helmy
Research is continuous for noninvasive tools for the prediction of portal hypertension than upper gastrointestinal endoscopy. Serum sCD163 correlates with hepatic venous pressure gradient, aiding in the prediction of portal hypertension. We aimed at investigating the role of sCD163 in the prediction of the presence and size of varices as well as a stratification tool for surveillance or prophylaxis by assessment of prognosis and risk of bleeding. Two hundred forty-three cirrhotic patients were divided into 3 groups: group I: no varices, group II: small-sized varices, and group III: medium-sized and large-sized varices...
March 2017: Journal of Interferon & Cytokine Research
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