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Cognitive imparement

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https://www.readbyqxmd.com/read/27056855/-cognitive-impairment-in-multiple-sclerosis
#1
REVIEW
Masaaki Niino, Yusei Miyazaki
While cognitive impairment is a major symptom of multiple sclerosis (MS), it is commonly overlooked. This may be explained by the fact that it is difficult to evaluate cognitive function in patients with MS using screening batteries for the detection of dementia such as the mini-mental state examination. Further more, cognitive impairment in MS typically involves domain-specific deficits such as imparement of sustained attention and information processing speed rather than global cognitive decline. Cognitive impairment may influence the daily living and social lines of affected patients...
April 2016: Brain and Nerve, Shinkei Kenkyƫ No Shinpo
https://www.readbyqxmd.com/read/26417823/should-measurement-of-cognition-be-part-of-recovery-programs-for-patients-with-psychotic-illness
#2
Mark Agius, Yuliya Zaytseva
The recovery model of schizophrenia is central to the devlopment of community services for patients with schizophrenia. However often when applying the recovery model of psychosis, often formal identification of cognitive imparements is not carried out, nor are interventions to improve cognitive functioning offered in a targeted way. Here we discuss how these issues relate to each other and argue for the use of cognitive testing in order to elp recovery in schizophrenia.
September 2015: Psychiatria Danubina
https://www.readbyqxmd.com/read/20471701/validity-of-the-telephone-interview-for-cognitive-status-tics-and-modified-tics-ticsm-for-mild-cognitive-imparment-mci-and-dementia-screening
#3
Eun Hyun Seo, Dong Young Lee, Shin Gyeom Kim, Ki Woong Kim, Do Hoon Kim, Bong Jo Kim, Moon-Doo Kim, Seong Yoon Kim, Young Hoon Kim, Jeong-Lan Kim, Jee Wook Kim, Seok Woo Moon, Joon Hyuck Park, Seung-Ho Ryu, Jong Choul Yoon, Nam Jin Lee, Chang Uk Lee, Jin Hyeong Jhoo, Ll Han Choo, Jong Inn Woo
This study aimed to validate the TICS and modified TICS (TICSm) in Korean elderly population and to compare MCI and dementia screening ability between TICS and TICSm. TICS and TICSm were administered to 70 cognitively normal (CN), 75 MCI, and 85 dementia subjects, with mini-mental state examination (MMSE) and other cognitive and functional measures. TICS and TICSm scores were highly correlated with other global cognitive and functional scores. The CN vs. dementia discrimination ability of both instruments was as excellent as that of MMSE (sensitivity/specificity at optimal cutoff: 87...
January 2011: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/16878354/-anticholinergic-medications-can-help-impared-cognitive-performance
#4
Felicitas Witte
No abstract text is available yet for this article.
July 2006: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/9926619/molecular-manipulations-of-extracellular-superoxide-dismutase-functional-importance-for-learning
#5
E D Levin, T C Brady, E C Hochrein, T D Oury, L M Jonsson, S L Marklund, J D Crapo
Extracellular superoxide dismutase (EC-SOD) controls the availability of extracellular superoxide (O2.-), which is important for a variety of physiological pathways, including the primary means of inactivating nitric oxide (NO). The role of EC-SOD in neurobehavioral function has been until now unexplored. In the current studies, the phenotypic expression of genotypic alterations of EC-SOD production in mice were characterized for spatial learning and memory. Dramatic impairments in spatial learning in the win-shift 8-arm radial maze were seen in both EC-SOD knockout mice and EC-SOD overexpressing mice...
September 1998: Behavior Genetics
https://www.readbyqxmd.com/read/8744410/the-older-rabbit-as-an-animal-model-implications-for-alzheimer-s-disease
#6
REVIEW
D S Woodruff-Pak, J Q Trojanowski
Eyeblink classical conditioning (EBCC) is impared in rabbits and humans during normal aging and severely disrupted in Alzheimer's disease (AD) and older Down's Syndrome patients (called DS/AD). To determine if older rabbit brains developed neuropathological evidence of Alzheimer-like pathology to account for impaired EBCC, the cerebellum and hippocampus of behaviorally tested rabbits aged 3 months to 7 years were probed using immunohistochemical techniques. Significant cell loss and gliosis were observed in some brain regions, but there was little or no deposition of beta-amyloid (A beta) or abnormal tau accumulations in telencephalic neurons, even in rabbits over 7 years of age...
March 1996: Neurobiology of Aging
https://www.readbyqxmd.com/read/8041485/nerve-growth-factor-increases-extracellular-acetylcholine-levels-in-the-parietal-cortex-and-hippocampus-of-aged-rats-and-restores-object-recognition
#7
C Scali, F Casamenti, M Pazzagli, L Bartolini, G Pepeu
Male Wistar rats (3- and 20-month-old) were perfused i.c.v. with 1.5 micrograms of either nerve growth factor (NGF) or cytochrome C daily for 14 days. At the end of the infusion, the object-recognition test was carried out and extracellular acetylcholine levels (ACh) were measured in the cortex and hippocampus by transversal microdialysis technique. In 20-month-old control rats, the cortical and hippocampal ACh levels were 35 and 45% lower, respectively, than in 3-month-old rats and the ability to discriminate between a familiar and new object was impared...
March 28, 1994: Neuroscience Letters
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