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"Clinician Update"

Shinkyoung Kim, Hyeungjune Kim, Dong In Jo, Sang-Jun Na, Yoon-Sik Jo
INTRODUCTION: Although ganglion cysts are common soft tissue tumors, nerve compression syndrome caused by a ganglion cyst in the lower extremities is very rare. Herein, we report a 57-year-old man who presented with hypoesthesia in the sole of his right foot for 6 months. We believe that reporting this rare case will help clinicians update their knowledge on possible causes of the plantar neuropathy, and avoid diagnostic delay. PRESENTATION OF CASE: The patient had pain and numbness in the inner right sole, as well as a tingling and dull sensation...
2018: International Journal of Surgery Case Reports
Costas Tsioufis, Felix Mahfoud, Giuseppe Mancia, Dimitrios Tousoulis
No abstract text is available yet for this article.
2017: Current Vascular Pharmacology
Freja Lærke Sand, Simon Francis Thomsen
Correct and rapid diagnosis of skin tumours often requires biopsy and histopathological examination to differentiate benign lesions such as seborrhoeic keratoses or melanocytic naevi from premalignant and malignant lesions such as malignant melanoma. Particularly, to the untrained eye, any benign skin tumour-pigmented or nonpigmented-is easily mistaken for a malignant lesion. Qualified clinical evaluation is paramount in order to reduce the frequency of unwarranted skin biopsies. Herein, the most common benign, premalignant, and malignant vulvar skin tumours are reviewed...
2017: International Scholarly Research Notices
(no author information available yet)
No abstract text is available yet for this article.
August 2015: Continuum: Lifelong Learning in Neurology
(no author information available yet)
No abstract text is available yet for this article.
August 2015: Continuum: Lifelong Learning in Neurology
(no author information available yet)
No abstract text is available yet for this article.
December 2014: Continuum: Lifelong Learning in Neurology
Nathan Jamieson, Davinder Singh-Grewal
Aims. Kawasaki disease is an acute systemic vasculitis and is the most common cause of acquired heart disease in children in the developed world. This review aims to synthesise recent insights into the disease and provide an update for clinicians on diagnostic and treatment practices. Methods. We conducted a review of the literature exploring epidemiology, aetiology, diagnosis, and management of Kawasaki disease. We searched MEDLINE, Medline In-Process, Embase, Google Scholar, and reference lists of relevant articles...
2013: International Journal of Pediatrics
Brian K Yorkgitis, Amy J Goldberg
No abstract text is available yet for this article.
May 2012: JAAPA: Official Journal of the American Academy of Physician Assistants
Giuseppe Tarantini, Valeria Gasparetto, Massimo Napodano, Chiara Fraccaro, Gino Gerosa, Giambattista Isabella
During trascatheter aortic valve implantation (TAVI) the native valve is not removed but crushed. Thus, a slight prosthesis insufficiency is not uncommon and has been reported in about 70% of patients for both available types of percutaneous valves. However, the definition of clinically "significant" valve regurgitation is not fully established yet. In most cases, aortic insufficiency is mild and clinical acceptable, however, severe insufficiency can occur. Paravalvular insufficiency is usually prevalent, and it may be the consequence of prosthesis/patient mismatch due to an undersizing of the implanted device or to an incomplete expansion of the prosthesis stent frame, or also to incorrect site of prosthesis implantation...
2011: American Journal of Cardiovascular Disease
George V Moukarbel, Deepak L Bhatt
No abstract text is available yet for this article.
January 17, 2012: Circulation
John F Carlquist, Jeffrey L Anderson
No abstract text is available yet for this article.
December 6, 2011: Circulation
Kristel De Keyzer, Steven Van Laecke, Patrick Peeters, Raymond Vanholder
Infection with human cytomegalovirus (CMV) is an important cause of morbidity and mortality in kidney transplant recipients. CMV disease is diagnosed based on the detection of viral replication by phosphoprotein 65 antigenemia or CMV DNA polymerase chain reaction in combination with typical signs and symptoms. Risk factors include CMV-seronegative recipients receiving a CMV-seropositive transplant, older donor age, exposure to cyclosporine and/or antilymphocyte antibody, rejection episodes, and impaired transplant function...
July 2011: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Wilfried Mullens, Wai Hong Wilson Tang
Up to 30% of cardiac resynchronization therapy (CRT) patients are considered to be "nonresponders." While the absolute number might increase because of the increased use of CRT, this proportion remains stable. As a result, there is a pressing need for guidelines for practicing clinicians to maximize the effectiveness of CRT. This clinician update describes easy-to-comprehend cases that might provide a practical insight for cardiologists, as well as for all professionals who take care of patients with heart failure who have undergone CRT...
May 2011: Congestive Heart Failure
C Brock Woodis
Nearly 50 million women each year are projected to reach menopause by 2030. Many of these women will experience vasomotor symptoms such as night sweats and hot flashes as they enter the menopausal transition. Up until the release of the findings of the Women's Health Initiative (WHI) studies, women were frequently prescribed hormone therapy (HT) to alleviate bothersome and sometimes debilitating menopausal symptoms as well as to prevent osteoporosis and coronary heart disease (CHD). Although the WHI studies were the first large, randomized, controlled trials that contradicted what was historically believed about the benefits of HT in postmenopausal women, important limitations including baseline demographics of WHI participants and investigation of only one HT strength/dosage form exist...
December 2010: Journal of Pharmacy Practice
Martin Fassnacht, Rossella Libé, Matthias Kroiss, Bruno Allolio
Adrenocortical carcinoma is a rare heterogeneous neoplasm with an incompletely understood pathogenesis and a poor prognosis. Previous studies have identified overexpression of insulin-like growth factor 2 (IGF-2) and constitutive activation of β-catenin as key factors involved in the development of adrenocortical carcinoma. Most patients present with steroid hormone excess, for example Cushing syndrome or virilization, or abdominal mass effects, but a growing proportion of patients with adrenocortical carcinoma (currently >15%) is initially diagnosed incidentally...
June 2011: Nature Reviews. Endocrinology
Alan C Braverman
No abstract text is available yet for this article.
July 13, 2010: Circulation
Arifaizad Abdullah, Shalimar Abdullah, Nor Hazla Mohd Haflah, Sharaf Ibrahim
Giant cell tumors are commonly found over the flexor tendon sheath of the hand and wrist. However, giant cell tumors in the knee joint are rare, especially in children. We report an interesting case of an 11-year-old girl who presented with a painful lump on her right knee that enlarged over time. Clinically, she had fullness over the anterolateral part of her knee. Magnetic resonance imaging revealed an encapsulated mass inferior to the patella. The tumor measured 3 x 3.5 x 1.5 cm. Histopathological findings confirmed that it was a tenosynovial giant cell tumor...
January 2010: Journal of the Chinese Medical Association: JCMA
Radhakrishnan Ramaraj, Vincent L Sorrell, Frank Marcus, Joseph S Alpert
Cardiomyopathy is a generic term for any heart disease in which the heart muscle is involved and functions abnormally. Recent developments and ongoing research in cardiology have led to descriptions of 3 previously less recognized or incompletely characterized cardiomyopathies. These entities are being increasingly noticed in adult patient populations. Primary care providers and cardiovascular specialists need to be aware of the clinical features of these illnesses and the best strategies for diagnosis and management...
August 2008: American Journal of Medicine
Paul E Szmitko, Subodh Verma
Complications of atherosclerosis remain the leading cause of morbidity and mortality in industrialized countries. Epidemiological studies have repeatedly demonstrated that moderate alcohol intake has a beneficial effect on cardiovascular disease. The purpose of this review is to examine the epidemiological and biological evidence supporting the intake of red wine as a means of reducing atherosclerosis. On the basis of epidemiological studies, moderate intake of alcoholic beverages, including red wine, reduces the risk of cardiovascular, cerebrovascular, and peripheral vascular disease in populations...
May 2005: American Journal of Physiology. Heart and Circulatory Physiology
Joanna J Wykrzykowska, Sekar Kathiresan, Ik-Kyung Jang
Antithrombotic therapy has become the cornerstone of the treatment for atherosclerotic cardiovascular disease. Unfractionated heparin (UFH) has been the thrombin inhibitor of choice for decades. UFH, however, has its deficiencies. To overcome these problems several direct thrombin inhibitors (DTIs) have been developed. These agents are capable of inactivating clot-bound thrombin more efficiently, and provide more predictable and safer anticoagulation in patients with of acute coronary syndromes (ACS). The initial studies of hirudin and bivalirudin in the clinical settings of acute myocardial infarction (AMI), unstable angina (UA) and percutaneous coronary interventions (PCI) conducted in the early 1990s proved to be disappointing...
February 2003: Journal of Thrombosis and Thrombolysis
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