Sabrina J Moyo, Joel Manyahi, Alasdair T M Hubbard, Rachel L Byrne, Nahya Salim Masoud, Said Aboud, Karim Manji, Bjørn Blomberg, Nina Langeland, Adam P Roberts
BACKGROUND: We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es Salaam, Tanzania. METHODS: Antimicrobial susceptibility was determined by disc diffusion E-test and broth microdilution. Genomes were completed using a hybrid assembly of Illumina and Oxford Nanopore Technologies sequencing reads and characterisation of the genetic context of resistance genes, multi-locus sequence types (STs) and phylogenetic analysis was determined bioinformatically...
September 3, 2021: Transactions of the Royal Society of Tropical Medicine and Hygiene