Marica Franzago, Paola Borrelli, Pierluigi Cavallo, Luciano Di Tizio, Diego Gazzolo, Marta Di Nicola, Liborio Stuppia, Ester Vitacolonna
Obesity and overweight are common and complex conditions influenced by multiple genetic and environmental factors. Several genetic variants located in the genes involved in clock systems and fat taste perception can affect metabolic health. In particular, the polymorphisms in CLOCK and BMAL1 genes were reported to be significantly related to cardiovascular disease, metabolic syndrome, sleep reduction, and evening preference. Moreover, genetic variants in the CD36 gene have been shown to be involved in lipid metabolism, regulation of fat intake, and body weight regulation...
March 29, 2024: International Journal of Molecular Sciences