keyword
https://read.qxmd.com/read/38435879/unveiling-a-rare-side-effect-a-report-of-a-unique-case-of-second-degree-type-2-sinoatrial-node-exit-block-induced-by-adenosine-infusion
#21
Dibyasundar Mahanta, Anup K Budhia, Rama Chandra Barik, Debasish Das, Debasis Acharya
Adenosine is a widely used pharmacologic agent in the field of cardiology, predominantly for the termination of supraventricular tachycardias and diagnostic purposes. Most of the side effects are short-lasting due to its very short half-life. Fatal complications of adenosine are rare but can include ventricular fibrillation, ventricular tachycardia, and asystole. Proper medical supervision and monitoring are crucial to minimize risks. We report a unique case of a second-degree type 2 sinoatrial node exit block following intravenous adenosine administration in a 25-year-old male presenting with palpitations...
January 2024: Curēus
https://read.qxmd.com/read/38434729/case-report-remote-magnetic-navigation-and-accessory-pathways-ablation-in-a-single-ventricle-young-adult-with-complex-corrective-surgeries
#22
Steliana Cosmina Paja, Viviana Gondoș, Silvia Deaconu, Eliza Cinteză, Radu Vătășescu
Supraventricular arrhythmias have become an increasingly significant contributor to the risk of mortality and morbidity in adults with complex congenital heart disease (CHD), especially in light of recent advances in palliative corrective surgeries. Because of their unique characteristics, they demand specific treatment approaches. While pharmaco-logical interventions are an option, they have limited effectiveness and may lead to side effects. Although performing radiofrequency ablation (RFA) can be exceptionally challenging in patients with complex CHD, due to particular vascular access and also modified anatomy, it has paved the way to enhance comprehension of the underlying mechanisms of supraventricular arrhythmias...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38431699/pregnancy-outcomes-in-patients-complicated-with-pre-excitation-syndrome
#23
JOURNAL ARTICLE
Kana Wang, Junguo Xin, Qing Hu, Xiaodong Wang, Haiyan Yu
INTRODUCTION: Pregnant women with pre-excitation syndrome are more likely to develop supraventricular tachycardia (SVT) during pregnancy and delivery, leading to an increased risk of adverse events. METHOD: This was a retrospective study of 309 pregnancies in 280 women (29 women had two pregnancies in this series) with pre-excitation syndrome who delivered at West China Second University Hospital from June 2011 to October 2021. All the 309 pregnant women with pre-excitation syndrome were divided into SVT and non-SVT groups to analyze the cardiac and obstetric complications...
March 2, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38431023/ep-corner-oscillations
#24
JOURNAL ARTICLE
William G Stevenson, Travis D Richardson
No abstract text is available yet for this article.
February 29, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38427036/-historical-developments-in-the-diagnosis-and-treatment-of-pre-excitation-syndromes-wpw
#25
REVIEW
Boris Rudic, Martin Borggrefe
In 1930, Wolff, Parkinson and White described the syndrome that bears their names. The mechanisms of supraventricular tachycardias were analyzed by brilliant electrocardiography interpretation by Pick and Langendorf. Wellens and Durrer using electrophysiologic studies analyzed the tachycardia mechanism invasively. In Germany the group by Seipel and Breithardt as well as Neuss and Schlepper studied the tachycardia mechanisms and response to antiarrhythmic drugs invasively by electrophysiological studies. Following the first successful interruption of an accessory pathway by Sealy in 1967, surgeons and electrophysiologists cooperated in Germany...
March 1, 2024: Herzschrittmachertherapie & Elektrophysiologie
https://read.qxmd.com/read/38425473/high-diagnostic-accuracy-of-long-term-electrocardiogram-interpretation-by-general-practitioners
#26
JOURNAL ARTICLE
Jarle Jortveit, Miroslav Boskovic, Edvard Liljedahl Sandberg, Jonas Vegsundvåg, Sigrun Halvorsen
AIMS: Traditional long-term ECG monitoring systems have primarily been used by cardiologist. New remote and wearable easy-to-use devices have led to increased use of ECG recordings also outside cardiology clinics. The aims of this study were to assess the feasibility and diagnostic accuracy of interpretation of the one-lead ECG recordings from a patch ECG device (ECG247 Smart Heart Sensor system) by general practitioners (GP). METHODS: Norwegian GPs were invited to digitally assess 10 long-term ECG recordings with different arrhythmias performed by the ECG247 Smart Heart Sensor system...
2024: International Journal of Telemedicine and Applications
https://read.qxmd.com/read/38424693/reduced-kinase-function-in-two-ultra-rare-tnni3k-variants-in-families-with-congenital-junctional-ectopic-tachycardia
#27
JOURNAL ARTICLE
Caroline Pham, Tamara T Koopmann, Jeffrey M Vinocur, Nico A Blom, Vivian Nogueira Silbiger, Kirti Mittal, Marianne Bootsma, Kaylin C A Palm, Sally-Ann B Clur, Daniela Q C M Barge-Schaapveld, Robert M Hamilton, Elisabeth M Lodder
Genetic missense variants in TNNI3K, encoding troponin-I interacting kinase, have been associated with dilated cardiomyopathy (DCM) and observed in families with supraventricular tachycardias (SVT). Previously, a family harboring the TNNI3K-c.1615A > G (p.Thr539Ala) variant presented with congenital junctional ectopic tachycardia (CJET), an arrhythmia that arises from the atrioventricular (AV) node and His bundle. However, this was a relatively small four-generational family with limited genetic testing (N = 3)...
February 29, 2024: Clinical Genetics
https://read.qxmd.com/read/38416160/-history-of-surgical-treatment-of-cardiac-arrhythmias-in-germany-surgical-treatment-of-ventricular-tachycardia-and-supraventricular-tachycardia-especially-pre-excitation-syndromes-wpw
#28
REVIEW
Helmut U Klein, Hans-Joachim Trappe, Günter Frank
The history of surgical treatment of ventricular tachycardias (VT) is short, lasting from 1978 until 1993. "Indirect procedures" with infarct scar resection were performed without electrophysiologic studies, whereas "direct procedures" consisted of either complete endocardial incisions ("encircling endocardial ventriculotomy") or large endocardial resections ("endocardial peel-off" technique) after precise epicardial and endocardial mapping procedures. In Germany, the first to report on intra-operative electrophysiologic mapping for VT treatment were Ostermeyer, Breithardt and Seipel in 1979...
February 28, 2024: Herzschrittmachertherapie & Elektrophysiologie
https://read.qxmd.com/read/38416159/-development-of-catheter-ablation-of-supraventricular-tachycardias-with-special-consideration-of-contributions-from-german-engineers-and-electrophysiologists
#29
REVIEW
Gerhard Hindricks, Verena Tscholl, Nikolaos Dagres, Philipp Attanasio, Martin Huemer
The development and clinical implementation of catheter ablation of supraventricular tachycardia is one of the outstanding achievements of modern cardiovascular treatment. Over a period of less than 40 years, a curative and safe treatment strategy for almost all forms of atrial arrhythmias has been developed and implemented. German electrophysiologists and engineers have made a significant contribution to this truly outstanding success story in modern medicine. Their contributions should be appropriately acknowledged because without them, the development of ablation technology and its worldwide dissemination would not have been possible...
February 28, 2024: Herzschrittmachertherapie & Elektrophysiologie
https://read.qxmd.com/read/38413418/incidence-of-fetal-arrhythmia-before-and-during-the-covid-19-pandemic-a-single-center-experience
#30
JOURNAL ARTICLE
Stefani Samples, Sheetal Patel, Simon Lee, Nina Gotteiner, Angira Patel
Fetal arrhythmias are rare and carry significant morbidity and mortality without appropriate treatment. Initial reports exist of fetal arrhythmia in the setting of maternal COVID-19 infection. Our study sought to evaluate incidence of fetal arrhythmia before and during the COVID-19 pandemic at our institution. This retrospective cohort study from a tertiary care fetal cardiac center utilized the institutional REDCap database to search fetal arrhythmia diagnostic codes. Medical records of mother-fetus dyads were reviewed and data were collected on diagnoses, gestational age, treatment regimen, and postnatal outcomes...
February 27, 2024: Pediatric Cardiology
https://read.qxmd.com/read/38411851/cardiotoxicity-after-synthetic-cathinone-use-two-cases-a-case-series-and-scoping-review
#31
REVIEW
K L Groenewegen, F M J Gresnigt, J J Nugteren-van Lonkhuyzen, C den Haan, E J F Franssen, R K Riezebos, D Ohana, D W de Lange
The cardiotoxic effects of synthetic cathinones remain largely unknown. In this study, we present two cases, a case series and a scoping review, to explore synthetic cathinone associated cardiotoxicity. Case 1 involved a 28-year-old male with non-ST-elevation myocardial infarction after ingesting a substance containing 4-methylmethcathinone (4-MMC), 3-methylmethcathinon (3-MMC), and methcathinone. Case 2 involved a 49-year-old male with ventricular fibrillation after 4-methylmethcathinone ingestion, who was diagnosed with severe three-vessel disease...
February 27, 2024: Cardiovascular Toxicology
https://read.qxmd.com/read/38405639/cardiac-arrest-after-adenosine-administration-in-compensatory-tachycardia-a-case-report
#32
Craig R Torres-Ness, Sonia A Desai
Compensatory tachycardia, an increased heart rate responding to stressors, requires careful consideration in treatment. This case report outlines a scenario where emergency medical services (EMS) misinterpreted a patient's electrocardiogram (EKG) as paroxysmal supraventricular tachycardia (PSVT) and administered adenosine, resulting in sudden cardiac arrest. Despite the rarity of deaths post-adenosine, this case highlights the potential risks of its use in inappropriate clinical scenarios. The patient, later diagnosed with a pulmonary embolism, had a compensatory heart rate that was disrupted after adenosine administration...
February 2024: Curēus
https://read.qxmd.com/read/38402192/comparing-the-effects-of-pulsed-and-radiofrequency-catheter-ablation-on-quality-of-life-anxiety-and-depression-of-patients-with-paroxysmal-supraventricular-tachycardia-a-single-center-randomized-single-blind-standard-controlled-trial
#33
RANDOMIZED CONTROLLED TRIAL
Ying Du, Shanshan Ma, Pan Yue, Ying Xu, Ya Wen, Mingzhu Ji, Lingxiao He, Dengbin Liao
BACKGROUND: Radiofrequency catheter ablation (RFCA) may lead to decreased quality of life (QOL) and increased anxiety and depression in patients with paroxysmal supraventricular tachycardia (PSVT), possibly due to the lack of selectivity of the ablation tissue and the long ablation time. In recent years, pulsed field ablation (PFA) has been used for the first time in China to treat PSVT patients because of its ability to ablate abnormal tissue sites in a precise and transient manner. This study was conducted to compare the effects of PFA and RFCA on QOL and psychological symptoms of PSVT patients...
February 24, 2024: Trials
https://read.qxmd.com/read/38399480/a-comprehensive-physiologically-based-pharmacokinetic-model-of-nadolol-in-adults-with-renal-disease-and-pediatrics-with-supraventricular-tachycardia
#34
JOURNAL ARTICLE
Samia Kalsoom, Muhammad Fawad Rasool, Imran Imran, Hamid Saeed, Tanveer Ahmad, Faleh Alqahtani
Nadolol is a long-acting non-selective β-adrenergic antagonist that helps treat angina and hypertension. The current study aimed to develop and validate the physiologically based pharmacokinetic model (PBPK) of nadolol in healthy adults, renal-compromised, and pediatric populations. A comprehensive PBPK model was established by utilizing a PK-Sim simulator. After establishing and validating the model in healthy adults, pathophysiological changes i.e., blood flow, hematocrit, and GFR that occur in renal failure were incorporated in the developed model, and the drug exposure was assessed through Box plots...
February 19, 2024: Pharmaceuticals
https://read.qxmd.com/read/38398488/do-implantable-cardioverter-defibrillators-prevent-sudden-cardiac-death-in-end-stage-renal-disease-patients-on-dialysis
#35
REVIEW
Beata Franczyk, Jacek Rysz, Robert Olszewski, Anna Gluba-Sagr
Chronic kidney disease patients appear to be predisposed to heart rhythm disorders, including atrial fibrillation/atrial flutter, ventricular arrhythmias, and supraventricular tachycardias, which increase the risk of sudden cardiac death. The pathophysiological factors underlying arrhythmia and sudden cardiac death in patients with end-stage renal disease are unique and include timing and frequency of dialysis and dialysate composition, vulnerable myocardium, and acute proarrhythmic factors triggering asystole...
February 19, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38392248/cardiovascular-complications-in-patients-with-heart-failure-and-covid-19-cardio-covid-19-20-registry
#36
JOURNAL ARTICLE
Mario Speranza, Juan D López-López, Pedro Schwartzmann, Igor Morr, María Juliana Rodríguez-González, Andrés Buitrago, Freddy Pow-Chon-Long, Luiz Carlos Passos, Víctor Rossel, Eduardo Roque Perna, Manuela Escalante, Alexander Romero, Andrea Alejandra Arteaga-Tobar, Daniel Quesada, Walter Alarco, Juan Esteban Gómez-Mesa
Since early 2020, different studies have shown an increased prevalence of COVID-19 and poorer prognosis in older adults with cardiovascular comorbidities. This study aimed to assess the impact of heart failure (HF) on cardiovascular complications, intensive care unit (ICU) admissions, and in-hospital mortality in patients hospitalized with COVID-19. The CARDIO COVID 19-20 registry includes 3260 hospitalized patients with a COVID-19 serological diagnosis between May 2020 and June 2021 from Latin American countries...
January 23, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38385329/plain-language-summary-of-the-safety-and-effectiveness-of-etripamil-for-atrioventricular-nodal-dependent-supraventricular-tachycardia-the-rapid-study
#37
REVIEW
James E Ip, Bruce S Stambler, David B Bharucha, Annette Green
WHAT IS THIS SUMMARY ABOUT?: This is a plain language summary of a clinical research study called RAPID. The study looked at the potential for how safe and effective etripamil was at stopping an episode of rapid heartbeats in people with atrioventricularnodal-dependent supraventricular tachycardia (AV-node-dependent SVT). An episode is used to describe the period of time when a person experiences an abnormally very fast heartbeat. This was done by comparing an investigational drug called etripamil with a placebo, each administered via a rapidly acting nasal spray...
February 22, 2024: Future Cardiology
https://read.qxmd.com/read/38384108/the-impact-of-supraventricular-arrhythmias-on-the-outcomes-of-guideline-compliant-implantable-cardioverter-defibrillator-programming
#38
JOURNAL ARTICLE
Padoemwut Teerawongsakul, Teetouch Ananwattanasuk, Ronpichai Chokesuwattanaskul, Muazzum Shah, Sangeeta Lathkar-Pradhan, Waseem Barham, Hakan Oral, Ranjan K Thakur, Krit Jongnarangsin, Tanyanan Tanawuttiwat
INTRODUCTION: Several implantable cardioverter defibrillators (ICD) programming strategies are applied to minimize ICD therapy, especially unnecessary therapies from supraventricular arrhythmias (SVA). However, it remains unknown whether these optimal programming recommendations only benefit those with SVAs or have any detrimental effects from delayed therapy on those without SVAs. This study aims to assess the impact of SVA on the outcomes of ICD programming based on 2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement and 2019 focused update on optimal ICD programming and testing guidelines...
February 21, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38383981/prior-history-of-atrial-fibrillation-and-arrhythmic-outcomes-data-from-the-wearit-ii-prospective-registry
#39
JOURNAL ARTICLE
Ido Goldenberg, Arwa Younis, Scott McNitt, Helmut Klein, Ilan Goldenberg, Valentina Kutyifa
INTRODUCTION: Wearable cardioverter defibrillator (WCD) is utilized in patients with assumed but not yet confirmed risk for sudden cardiac death (SCD). Many of these patients also present with atrial fibrillation (AF). However, the rate of WCD-detected ventricular or atrial arrhythmia events in this specific high-risk cohort is not well understood. METHODS: In WEARIT-II, the cumulative probability of any sustained or nonsustained VT/VF (WCD-treated and nontreated), and atrial/supraventricular arrhythmias during WCD use was assessed using the Kaplan-Meier method by prior AF, with comparisons by the log-rank test...
February 21, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38372622/the-outcomes-of-patients-with-septic-shock-treated-with-propafenone-compared-to-amiodarone-for-supraventricular-arrhythmias-are-related-to-end-systolic-left-atrial-volume
#40
JOURNAL ARTICLE
P Waldauf, M Porizka, J Horejsek, M Otahal, E Svobodova, I Jurisinova, M Maly, T Brozek, J Rulisek, P Trachta, T Tencer, A Krajcova, F Duska, M Balik
BACKGROUND: A recently published trial has shown no differences in outcomes between patients with new-onset supraventricular arrhythmia (SVA) in septic shock treated with either propafenone or amiodarone. However, these outcome data have not been evaluated in relation to the presence or absence of a dilated left atrium (LA). METHODS: Patients with SVA and a left ventricular ejection fraction ≥35% were randomized to receive intravenous propafenone (70mg bolus followed by 400-840mg/24h) or amiodarone (300mg bolus followed by 600-1800mg/24h)...
February 19, 2024: European Heart Journal. Acute Cardiovascular Care
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