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mean systemic filling pressure

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https://www.readbyqxmd.com/read/29127237/metaboreflex-mediated-hemodynamic-abnormalities-in-individuals-with-coronary-artery-disease-without-overt-signs-or-symptoms-of-heart-failure
#1
Sara Magnani, Silvana Roberto, Gianmarco Sainas, Raffaele Milia, Girolamo Palazzolo, Lucia Cugusi, Virginia Pinna, Azzurra Doneddu, Seyed Alireza Hosseini Kakhak, Filippo Tocco, Giuseppe Mercuro, Antonio Crisafulli
This study was devised to investigate the effect of coronary artery disease (CAD) without overt signs of heart failure on the cardiovascular responses to muscle metaboreflex activation. We hypothesized that any CAD-induced pre-clinical systolic and/or diastolic dysfunction could impair hemodynamic response to the metaboreflex test. Twelve males diagnosed with CAD without any sign or symptoms of heart failure and 11 age-matched healthy controls (CTL) participated in the study. Subjects performed a post-exercise muscle ischemia (PEMI) test to activate the metaboreflex...
November 10, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29094424/fetal-sheep-central-hemodynamics-and-cardiac-function-during-ascending-aorta-occlusion
#2
Heikki Huhta, Juulia Junno, Mervi Haapsamo, Tiina Erkinaro, Pasi Ohtonen, Lowell E Davis, A Roger Hohimer, Ganesh Acharya, Juha Rasanen
Fetal aortic isthmus (AoI) allows communication between left (LV) and right (RV) ventricular outputs and represents arterial watershed between the brachiocephalic (brain) and subdiaphragmatic (placenta) circulations. To understand the capability of AoI to maintain the balance between upper and lower body circulations, we performed a complete fetal ascending aorta occlusion in 9 chronically instrumented sheep at near term gestation. We hypothesized that the occlusion would significantly decrease LV output and concomitantly increase RV output in order to maintain adequate systemic cardiac output and perfusion pressure to the fetal brain circulation through retrograde filling of the AoI...
November 2, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29068081/a-new-pressure-guided-management-tool-for-epidural-space-detection-feasibility-assessment-on-a-simulator
#3
Massimiliano Carassiti, Alessia Mattei, Rossella Quarta, Carlo Massaroni, Paola Saccomandi, Marco Tesei, Roberto Setola, Emiliano Schena
The detection of epidural space is usually performed by the technique of loss of resistance (LOR) without technological support, although there are few commercial options. We sought to design and develop a new noninvasive system able to detect the LOR without any changes to the conventional procedure. It allows detecting the LOR by a custom made algorithm. The system provides a visual and acoustic feedback when the LOR is detected. We optimized the detection algorithm and investigated the performance of the system during experiments on a custom simulator...
October 25, 2017: Artificial Organs
https://www.readbyqxmd.com/read/29055384/the-central-nervous-system-pressure-histogram-in-hydrocephalus-and-hydromyelia
#4
H F Williams
This work makes proposals on the relationship between intracranial pressure (ICP) and hydrocephalus that changes over time with the evolution of the disease. This includes the cerebrospinal fluid (CSF) filling mechanism that leads to an increase in mode pressure if excess fluid volume exacerbates the obstructive process. Elevation in mode occurs because pressure in the central nervous system (CNS) represents a state of reduced flow, rather than an abnormality of volume. Diseases that cause elevated mode pressure by means of a primary edema can lead to hydrocephalus if there is sufficient time and obstruction to flow for the filling mechanism to act...
October 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29017460/27-gauge-and-25-gauge-vitrectomy-day-surgery-for-idiopathic-epiretinal-membrane
#5
Saigen Naruse, Hiroyuki Shimada, Ryusaburo Mori
BACKGROUND: This study compared the postoperative outcomes of 27-gauge (G) and 25-G vitrectomy performed for the treatment of idiopathic epiretinal membrane (ERM). METHODS: The study design was single center, retrospective, interventional case series. Two hundred consecutive eyes that underwent primary vitrectomy for ERM (27-G vitrectomy in 100 eyes and 25-G vitrectomy in 100 eyes) were studied for 6 months. In all eyes, scleral tunnels were made using angle incisions, and air or gas exchange was performed...
October 10, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28991824/the-%C3%AE-blocker-esmolol-restores-the-vascular-waterfall-phenomenon-after-acute-endotoxemia
#6
Wei Du, Dawei Liu, Yun Long, Xiaoting Wang
BACKGROUND: A vascular waterfall occurs when the critical closing pressure is greater than the mean systemic filling pressure. Because the waterfall phenomenon likely exists in the microcirculation, β1-receptor blockers such as esmolol could have some effect on microcirculation and vascular waterfall. OBJECTIVES: To determine whether a vascular waterfall exists during septic shock and to assess the effects of vasopressors and β-blockers on vascular waterfall. DESIGN: Sixteen mongrel dogs were mounted with ultrasonic flow probes to measure renal blood flow...
December 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28951467/a-low-pressure-oxygen-storage-system-for-oxygen-supply-in-low-resource-settings
#7
Roger P Rassool, Bryn A Sobott, David J Peake, Bagayana S Mutetire, Peter P Moschovis, Jim Fp Black
BACKGROUND: Widespread access to medical oxygen would reduce global pneumonia mortality. Oxygen concentrators are one proposed solution, but they have limitations, in particular vulnerability to electricity fluctuations and failure during blackouts. The low-pressure oxygen storage system addresses these limitations in low-resource settings. This study reports testing of the system in Melbourne, Australia, and nonclinical field testing in Mbarara, Uganda. METHODS: The system included a power-conditioning unit, a standard oxygen concentrator, and an oxygen store...
September 26, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28912258/frank-starling-mechanism-and-short-term-adjustment-of-cardiac-flow
#8
José Guilherme Chaui-Berlinck, Luiz Henrique Alves Monteiro
The Frank-Starling Law of the heart is a filling-force mechanism (FFm), a positive relationship between the distension of a ventricular chamber and its force of ejection, and such a mechanism is found across all the studied vertebrate lineages. The functioning of the cardiovascular system is usually described by means of the cardiac and vascular functions, the former related to the contractility of the heart and the latter related to the after-load imposed to the ventricle. The crossing of these functions is the so-called operation point, and the FFm is supposed to play a stabilizing role for the short-term variations in the working of the system...
September 14, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28902431/cardiovascular-predictors-of-death-in-patients-with-cirrhosis
#9
Maurizio Cesari, Anna Chiara Frigo, Marta Tonon, Paolo Angeli
Cirrhotic cardiomyopathy is associated with poor outcomes in patients with cirrhosis. We investigated if subclinical cardiac morphologic and functional modifications can influence survival in cirrhotic patients during follow-up. A series of cirrhotic patients without cardiovascular or pulmonary disease underwent standard and tissue Doppler echocardiography to assess left ventricular (LV) geometry, systo/diastolic function and the main haemodynamic parameters. After baseline evaluation 115 cirrhotic patients were followed up for at least 6 years...
September 13, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28852442/cardiovascular-effects-of-nitrergic-system-of-the-pedunculopontine-tegmental-nucleus-in-anesthetized-rats
#10
Mohammad Naser Shafei, Tahereh Nikyar, Mahmoud Hosseini, Saeed Niazmand, Maryam Paseban
OBJECTIVES: Nitric oxide (NO) is an important neurotransmitter in central nervous system involved in central cardiovascular regulation. The presence of NO in the pedunculopontine tegmental (PPT) nucleus has been shown, but its cardiovascular effect has not been determined. In the present study, the cardiovascular effect of NO in the PPT nucleus was evaluated. MATERIALS AND METHODS: After induction of anesthesia, a polyethylene catheter (PE-50) filled with heparinized saline inserted into the femoral artery, and the blood pressure (BP) and heart rate (HR) were continuously recorded...
July 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28719986/three-dimensional-printing-of-surgical-clips-an-in-vitro-pilot-study-and-trial-of-efficacy
#11
Noah E Canvasser, Shuvro De, Ersin Koseoglu, Aaron H Lay, Igor Sorokin, Raul Fernandez, Jeffrey A Cadeddu
INTRODUCTION AND OBJECTIVE: Three-dimensional (3D) printing applications have increased over the past decade. Our objective was to test rapid prototyping of a 3D printed surgical clip for intraoperative use. MATERIALS AND METHODS: Our prototype was modeled after the 10 mm Weck(®) Hem-o-lok(®) polymer clip (Teleflex, Inc., Wayne, PA). A 3D computer-aided design model of the Hem-o-lok clip was reverse engineered using commercial microscopy and printing was done using an Objet Connex500 multijetting system (Stratasys, Eden Prairie, MN)...
August 11, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28702633/a-dft-study-of-h-dissolution-into-the-bulk-of-a-crystalline-ni-111-surface-a-chemical-identifier-for-the-reaction-kinetics
#12
Mahdi Shirazi, Annemie Bogaerts, Erik C Neyts
In this study, we investigated the diffusion of H-atoms to the subsurface and their further diffusion into the bulk of a Ni(111) crystal by means of density functional theory calculations in the context of thermal and plasma-assisted catalysis. The H-atoms at the surface can originate from the dissociative adsorption of H2 or CH4 molecules, determining the surface H-coverage. When a threshold H-coverage is passed, corresponding to 1.00 ML for the crystalline Ni(111) surface, the surface-bound H-atoms start to diffuse to the subsurface...
July 26, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28683486/-role-of-intraoperative-indirect-channelography-in-glaucoma-stent-implantation
#13
Christopher Wirbelauer, Charlotte Nora Mertens
Several glaucoma stents are available to surgically reduce the intraocular pressure in primary open-angle glaucoma (POAG). In comparison to conjunctival opening procedures, the advantages of microinvasive glaucoma surgery (MIGS) are relatively atraumatic ab-interno procedures through a paracentesis, conjunctival sparing for later filtrating surgery, and possible combined cataract surgery. In this overview, the principle of intraoperative indirect channelography as a decision criterion for the individual selection of glaucoma stent implantation is presented...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28669372/observational-study-on-safety-of-prehospital-bls-cpap-in-dyspnea
#14
Novneet Sahu, Patrick Matthews, Kathryn Groner, Mia A Papas, Ross Megargel
Introduction Continuous positive airway pressure (CPAP) improves outcomes in patients with respiratory distress. Additional benefits are seen with CPAP application in the prehospital setting. Theoretical safety concerns regarding Basic Life Support (BLS) providers using CPAP exist. In Delaware's (USA) two-tiered Emergency Medical Service (EMS) system, BLS often arrives before Advanced Life Support (ALS). Hypothesis This study fills a gap in literature by evaluating the safety of CPAP applied by BLS prior to ALS arrival...
July 3, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28629628/left-ventricular-outflow-tract-obstruction-and-its-impact-on-systolic-ventricular-function-and-exercise-capacity-in-adults-with-a-subaortic-right-ventricle
#15
Annina Stauber, Céline Wey, Matthias Greutmann, Daniel Tobler, Kerstin Wustmann, Andreas Wahl, Emanuela R Valsangiacomo Buechel, Matthias Wilhelm, Markus Schwerzmann
BACKGROUND: In biventricular hearts the filling and contractility of one ventricle affects the performance of the other. In this study, we compared right ventricular systolic function and exercise capacity in patients with a subaortic right ventricle (RV) in relation to the presence of a left ventricular outflow tract obstruction (LVOTO). METHODS: Retrospective chart review of adults with congenitally corrected transposition of the great arteries (ccTGA) or with a previous atrial switch procedure for complete TGA (D-TGA)...
June 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28611883/altitude-related-change-in-endotracheal-tube-cuff-pressures-in-helicopter-ems
#16
Stacy N Weisberg, Jonathan C McCall, Joseph Tennyson
INTRODUCTION: Over-inflation of endotracheal tube (ETT) cuffs has the potential to lead to scarring and stenosis of the trachea.1, 2,3, 4 The air inside an ETT cuff is subject to expansion as atmospheric pressure decreases, as happens with an increase in altitude. Emergency medical services helicopters are not pressurized, thereby providing a good environment for studying the effects of altitude changes ETT cuff pressures. This study aims to explore the relationship between altitude and ETT cuff pressures in a helicopter air-medical transport program...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28550170/right-atrial-pressure-and-venous-return-during-cardiopulmonary-bypass
#17
Per W Moller, Bernhard Winkler, Samuel Hurni, Paul Philipp Heinisch, Andreas Bloch, Soren Sondergaard, Stephan M Jakob, Jukka Takala, David Berger
The relevance of right atrial pressure (RAP) as the backpressure for venous return (QVR) and mean systemic filling pressure as upstream pressure is controversial during dynamic changes of circulation. To examine the immediate response of QVR (sum of caval vein flows) to changes in RAP and pump function, we used a closed-chest, central cannulation, heart bypass porcine preparation (n = 10) with venoarterial extracorporeal membrane oxygenation. Mean systemic filling pressure was determined by clamping extracorporeal membrane oxygenation tubing with open or closed arteriovenous shunt at euvolemia, volume expansion (9...
August 1, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28479464/embo-evar-a-technique-to-prevent-type-ii-endoleak-a-single-center-experience
#18
Massimiliano Natrella, Alessandro Rapellino, Federico Navarretta, Gianluca Iob, Massimo Cristoferi, Matteo Castagnola, Gianmarco Lunardi, Luca Duc, Gianluca Fanelli, Andrea Peruzzo Cornetto, Teodoro Meloni, Flavio Peinetti
BACKGROUND: Intraprocedural aneurysm sac embolization (embo-EVAR) during endovascular abdominal aneurysm repair (EVAR) using coils and fibrin glue is a technique for preventing type II endoleak (EII). Our aim is to evaluate feasibility, safety and clinical outcome of this promising approach. MATERIALS AND METHODS: A retrospective clinical case analysis of 72 patients who underwent EVAR during the period 2011-2014. Two groups were compared at 6 and 12 months follow-up with contrast media computed tomography scan and contrast-enhanced ultrasound (CEUS) imaging: consecutively, 36 patients (group A) treated with classic EVAR and 36 patients (group B) treated with embo-EVAR...
October 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28393776/serial-semi-invasive-hemodynamic-assessment-following-pericardiectomy-for-chronic-constrictive-pericarditis
#19
Ujjwal Kumar Chowdhury, Poonam Malhotra Kapoor, Adil Rizvi, Vishwas Malik, Sandeep Seth, Rajiv Narang, Mani Kalaivani, Sarvesh Pal Singh, Sathiya Selvam
OBJECTIVES: This study was designed to prospectively investigate the effects of pericardiectomy via median sternotomy on intra- and postoperative hemodynamics by a new semi-invasive device (Flotrac/VigileoTM monitor) using arterial pressure waveform analysis. PATIENTS AND METHODS: Thirty consecutive patients aged 15 to 55 years (mean+SD, 31.73 + 13.53 years), who had undergone total pericardiectomy via median sternotomy underwent serial hemodynamic evaluation. FlotracTM Sensor - derived stroke volume, stroke volume variation, systemic vascular resistance index (SVRI), cardiac index and right atrial pressure were measured just before and after pericardiectomy, at 12 hours, 24 hours, 48 hours, 72 hours and at discharge postoperatively...
April 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28390451/a-comparative-volumetric-evaluation-of-four-obturating-techniques-in-primary-teeth-using-cone-beam-computed-tomography
#20
Aparna Singh, Nidhi Gupta, Nidhi Agarwal, Dipanshu Kumar, Ashish Anand
PURPOSE: To compare the volume of root canals of primary teeth filled by four different obturating techniques: (1) lentulospiral (LS); (2) insulin syringe (IS); (3) endodontic pressure syringe (EPS); and (4) the NaviTip system (NS) using cone beam computed tomography (CBCT). METHODS: 76 root canals of primary posterior teeth were selected and divided into four groups, according to the obturation technique. Biomechanical preparation of each root canal was completed with a number 30 K-file, and the volumes of the canals were then measured using CBCT...
March 15, 2017: Pediatric Dentistry
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