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https://www.readbyqxmd.com/read/27894451/eczema-and-urticaria-as-manifestations-of-undiagnosed-and-rare-diseases
#1
REVIEW
Molly J Youssef, Yvonne E Chiu
Eczema and urticaria are common disorders encountered in pediatric patients, but they may occasionally be the presenting complaint in a child with an underlying rare disease. Immunodeficiency syndromes should be suspected when eczema is associated with neonatal onset, recurrent infections, chronic lymphadenopathy, or failure to thrive. Nutritional deficiencies and mycosis fungoides are in the differential diagnosis for a child with a recalcitrant eczematous eruption. Autoinflammatory syndromes should be suspected in a child with chronic urticaria, fever, and other systemic signs of inflammation...
February 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/27803824/successful-treatment-of-disseminated-bacillus-calmette-gu%C3%A3-rin-disease-in-an-hiv-infected-child-with-a-linezolid-containing-regimen
#2
Srđan Roglić, Drusia Dickson, Branko Miše, Klaudija Višković, Vera Katalinić-Janković, George Rutherford, Josip Begovac
Upon HIV infection diagnosis, an 8-month-old boy was transferred for evaluation of worsening respiratory distress requiring mechanical ventilation. Pneumocystis jirovecii pneumonia (PCP) was diagnosed; the boy also had a nonhealing ulcer at the site of vaccination with Statens Serum Institut (Danish strain) Bacillus Calmette-Guérin (BCG) vaccine and associated axillary lymphadenopathy. PCP treatment resulted in weaning from mechanical ventilation. Antimycobacterial treatment was immediately attempted but was discontinued because of hepatotoxicity...
2016: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/27749663/clinical-and-epidemiologic-features-of-visceral-leishmaniasis-in-children-in-southwestern-china-a-retrospective-analysis-from-2001-to-2015
#3
Ruixue Miao, Zhiling Wang, Qin Guo, Yang Wen, Qiong Liao, Yu Zhu, Min Shu, Chaomin Wan
BACKGROUND: Visceral Leishmaniasis (VL) is a life-threatening parasitic infection transmitted by phlebotomine sandflies. We undertook this study to analyze the clinical features of pediatric VL in a population of Chinese children. METHODS: A retrospective study was performed with pediatric patients (≤14years) diagnosed with VL based on bone-marrow biopsy, serology and diagnosis based on clinical manifestation and the improvement after the experimental drug when negative bone marrow and serology results were shown...
September 30, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27717995/juvenile-myelomonocytic-leukemia-presenting-as-bilateral-breast-masses
#4
Michele N Edison, M Cody O'Dell, Haley P Letter, Kurt Scherer, Jennifer L Williams
An 8-year-old girl presented with bilateral breast masses and was subsequently diagnosed with juvenile myelomonocytic leukemia. Juvenile myelomonocytic leukemia is a rare myelodysplastic syndrome that typically presents in boys younger than 3 years of age with splenomegaly, lymphadenopathy and skin findings. Bilateral breast masses in a child are rare and, as such, present a diagnostic dilemma due to the relative paucity of cases in the literature. We present a case of granulocytic sarcoma of the breasts in a patient with juvenile myelomonocytic leukemia...
October 7, 2016: Pediatric Radiology
https://www.readbyqxmd.com/read/27660720/coexistence-of-a-ghon-complex-pott-s-disease-and-hip-arthritis-in-a-child
#5
Ozgul Yigit, Meltem Erol, Ozlem Bostan Gayret, Isıl Ustun, Selami Ulas
INTRODUCTION: Tuberculosis remains a major public health problem in developing countries. Diagnosing extrapulmonary tuberculosis can be difficult, as it requires a higher index of suspicion than primary tuberculosis. Extrapulmonary tuberculosis may mimic malignancies and many other diseases, so it should be included in the differential diagnosis. Here, we present a case of extrapulmonary tuberculosis associated with Pott's disease and hip arthritis in a patient who recovered after 12 months of antituberculosis therapy...
July 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27652300/impact-and-safety-of-endoscopic-ultrasound-guided-fine-needle-aspiration-on-patients-with-cirrhosis-and-pyrexia-of-unknown-origin-in-india
#6
Narendra Choudhary, Rinkesh Kumar Bansal, Rajesh Puri, Rajiv Ranjan Singh, Mukesh Nasa, Vinit Shah, Haimanti Sarin, Mridula Guleria, Sanjiv Saigal, Neeraj Saraf, Randhir Sud, Arvinder S Soin
BACKGROUND AND AIMS: Etiologic diagnosis of pyrexia of unknown origin is important in patients with cirrhosis for optimal management and to prevent flare up of infectious disease after liver transplantation. However, there is very limited literature available on this subject. The present study aimed to examine the safety and impact of endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) in patients with cirrhosis. METHODS: The study was conducted between January 2014 and January 2016 at a tertiary care center...
September 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27650624/rapid-diagnosis-of-mycobacterium-genavense-disseminated-infection-by-the-microseq-500-a-case-report-in-a-two-year-old-hiv-negative-child
#7
Marco Arosio, Maurizio Ruggeri, Sabrina Buoro, Anna Locatelli, Gaia Ortalli, Lorenzo D'Antiga, Claudio Farina
This paper evaluates the capability of MicroSeq 500 instrument to improve the diagnosis of Mycobacterium genavense The strain was isolated from a two year old child admitted to our hospital for hepatosplenomegaly and massive abdominal lymphadenopathies. DNA was extracted from a lymph node and examined by amplifying 500 bp at the 5' end of 16S rRNA gene using MicroSeq 500 16S rDNA Bacterial Identification PCR kit. Sequencing reactions were performed with MicroSeq 500 16S rDNA Bacterial Identification Sequencing kit (Applied Biosystems, USA)...
September 2016: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/27649674/disseminated-bacille-calmette-gu%C3%A3-rin-disease-in-saudi-children-clinical-profile-microbiology-immunology-evaluation-and-outcome
#8
E Bukhari, F Alaklobi, H Bakheet, A Alrabiaah, F Alotibi, F Aljobair, M Alshamrani, E Alaki, F Alnahdi, A Alodyani, F Alzamil
OBJECTIVE: The bacille Calmette Guérin (BCG) vaccine is administered worldwide to prevent tuberculosis. Although, Post BCG vaccination complications like disseminated BCG infections are rare and immunocompromised children are at high risk of developing BCG-related complications including BCG-lymphadenitis and other disseminated diseases. PATIENTS AND METHODS: This was a prospective study of children who developed disseminated BCG after vaccination who were admitted in three tertiary care hospital in Riyadh, Saudi Arabia, in the year 2015...
September 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27598022/role-of-whole-body-mr-with-dwibs-in-child-s-bartonellosis
#9
E Rossi, A Perrone, D Narese, M Cangelosi, S Sollai, A Semeraro, M Mortilla, C Defilippi
Cat-scratch disease (CSD) is a zoonosis in children, result of infection by Bartonella henselae, a gram-negative bacillus. Infection is generally characterized by regional and self-limited lymphadenopathy after exposure to a scratch or bite from a cat. Rarely, B. henselae is cause of fever of unknown origin (FUO), with dissemination to various organs, most often involving the reticuloendothelial system (liver, spleen, bone marrow), mimicking an inflammatory rather than a lymphoproliferative disease. Whole-body Magnetic Resonance Imaging (WBMRI), in association with diffusion-weighted imaging (DWIBS), allows a comprehensive evaluation of pediatric patients, without the risks inherent to ionizing radiation...
July 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27579193/autoimmune-lymphoproliferative-syndrome-a-rare-cause-of-disappearing-hdl-syndrome
#10
Swetha Sriram, Avni Y Joshi, Vilmarie Rodriguez, Seema Kumar
The term disappearing HDL syndrome refers to development of severe high density lipoprotein cholesterol (HDL-C) deficiency in noncritically ill patients with previously normal HDL-C and triglyceride levels. Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of the immune system due to an inability to regulate lymphocyte homeostasis resulting in lymphadenopathy and hepatosplenomegaly. We describe a 17-year-old boy who was evaluated in the lipid clinic for history of undetectable or low HDL-C and low density lipoprotein cholesterol (LDL-C) levels...
2016: Case Reports in Immunology
https://www.readbyqxmd.com/read/27560476/cutaneous-tuberculosis-occurring-after-a-skin-cut-in-a-child
#11
Gulsen Akkoc, Eda Kepenekli Kadayifci, Ayse Karaaslan, Serkan Atici, Nurhayat Yakut, Sevilya Ocal Demir, Gamze Akbas, Leyla Zeliha Cinel, Ahmet Soysal, Mustafa Bakir
BACKGROUND: Tuberculosis is a common problem in Turkey, and cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis. Herein, the authors describe a case of cutaneous tuberculosis (lupus vulgaris) occurring after contact with a sheep. CASE: A 15-year-old boy was admitted to Marmara University School of Medicine Pendik Training and Research Hospital (Istanbul, Turkey) with delayed wound healing on the left index finger and left axillary lymphadenopathy...
August 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/27540457/streptococcal-pharyngitis-in-a-two-month-old-infant-a-case-report
#12
Mohammad Reza Sharif, Marzieh Aalinezhad, Seyyed Mohammad Sajad Sajadian, Mostafa Haji Rezaei
INTRODUCTION: Group A β-hemolytic Streptococcus is the most common cause of bacterial pharyngitis among 5 - 15-year-old children, but it is uncommon in children less than three years old and rarely happens in infants less than one year old. CASE PRESENTATION: The patient was a 62-day-old female infant who presented with fever and poor feeding since two days before admission. At the time of admission, the patient was febrile and ill. Upon examination, a rectal temperature of 38...
May 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27477178/trichotillomania-bizzare-patern-of-hair-loss-at-11-year-old-girl
#13
Jana Zímová, Pavlína Zímová
Trichotillomania (TTM) is defined by the Diagnostics and Statistic Manual of Mental Disorders, 4th edition (DMS-IV) as hair loss from a patient`s repetitive self-pulling of hair. The disorder is included under anxiety disorders because it shares some obsessive-compulsive features. Patients have the tendency towards feelings of unattractiveness, body dissatisfaction, and low self-esteem (1,2). It is a major psychiatric problem, but many patients with this disorder first present to a dermatologist. An 11-year-old girl came to our department with a 2-month history of diffuse hair loss on the frontoparietal and parietotemporal area (Figure 1)...
June 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27442634/soft-tissue-rosai-dorfman-disease-in-child-a-case-report-and-literature-review
#14
Yunlan Xu, Bingqiang Han, Jie Yang, Jing Ma, Ji Chen, Zhigang Wang
BACKGROUND: Rosai-Dorfman disease was commonly characterized as massive, painless, bilateral, symmetric cervical lymphadenopathy, with fever, leukocytosis, and elevated sedimentation rate. However, soft tissue Rosai-Dorfman disease (STRDD) is a rare benign tumor. METHODS: We hereby present 1 case of a 17-month-old girl, an isolated subcutaneous mass was detected on her right forearm, and no signs of pain, swelling, or erythema were observed at the site. RESULTS: The patient underwent an excisional biopsy for the mass...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27408344/atypical-presentation-of-acute-lymphoblastic-leukemia-in-a-7-year-old-child
#15
C G Delhi Kumar, Niranjan Biswal, Smita Kayal
Seven year child, who had intussusception 4 month before, readmitted for fever and walking difficulty. On examination, child had mild pallor and kyphosis of the spine but no organomegaly, lymphadenopathy or bone pain . Further evaluation revealed hypercalcemia, diffuse osteoporosis with vertebral fracture. Peripheral smear showed no blasts or pancytopenia. Bone marrow aspiration turned out to be a pre B cell ALL. This child had many atypical presentations like intussusception, osteoporosis, vertebral collapse and hypercalcemia without any classical features of ALL...
June 2016: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/27397873/probable-griseofulvin-induced-drug-reaction-with-eosinophilia-and-systemic-symptoms-in-a-child
#16
Robert J Smith, Markus D Boos, Patrick McMahon
A 9-year-old boy presented with fever, rash, anterior cervical lymphadenopathy, high liver enzymes, atypical lymphocytosis, and eosinophilia (drug reaction with eosinophilia and systemic symptoms [DRESS]). His history was notable for having taken griseofulvin for 3 weeks prior to onset of these findings. He improved after treatment with oral prednisone. We present a rare case of probable DRESS secondary to griseofulvin.
September 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27368445/pediatric-lymphedema-caused-by-diffuse-cervical-lymphadenopathy-a-case-report-and-review-of-the-literature
#17
Sarah A Gitomer, Carla M Giannoni, Karina T Cañadas
Pediatric head and neck lymphedema is rare and there have not been any reported cases in children. Here we discuss severe, diffuse head and neck lymphedema in a child caused by compression of the internal jugular veins by lymphadenopathy from Kawasaki's disease. With steroid and intravenous immunoglobulin treatment, the lymphadenopathy improved and facial edema slowly resolved. In review of the literature, complications of head and neck lymphedema including airway obstruction and blindness are discussed. This case highlights the importance of the pediatric otolaryngologist considering lymphedema as a cause for facial swelling and monitoring for complications of lymphedema...
August 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27352842/clinico%C3%A2-%C3%A2-laboratory-profile-of-scrub-typhus-an-emerging-rickettsiosis-in-india
#18
Dinesh Kumar Narayanasamy, Arul Kumaran Arunagirinathan, Revathi Krishna Kumar, V D Raghavendran
OBJECTIVE: To study the clinical and laboratory profile of pediatric scrub typhus in rural south India. METHODS: This is a descriptive study of the clinical and laboratory features of 117 children with IgM ELISA proven scrub typhus out of 448 children, who were admitted in the Pediatric ward of a tertiary care hospital, during the study period of November 2014 through March 2015. RESULTS: Fever was present in all 117 children, with mean duration of fever at admission as 9 d...
November 2016: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/27304887/papulonecrotic-tuberculid-a-rare-skin-manifestation-in-a-child-with-mesenteric-tuberculous-lymphadenopathy
#19
Soo Hyeon Bae, Sook Jung Yun, Jee-Bum Lee, Seong-Jin Kim, Seung-Chul Lee, Young Ho Won
is missing (Short communication).
June 15, 2016: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/27156800/-cutaneous-leishmaniasis-due-to-leishmania-infantum-associated-with-hiv
#20
B-A Diatta, M Diallo, S Diadie, B Faye, M Ndiaye, H Hakim, S Diallo, B Seck, S-O Niang, A Kane, M-T Dieng
BACKGROUND: In Senegal, reported cases of cutaneous leishmaniasis are often due to Leishmania major. Immunosuppression related to HIV infection contributes to the emergence of leishmaniasis in humans and to cutaneous localization of viscerotropic species. We report the first observed case in Senegal of opportunistic cutaneous leishmaniasis due to Leishmania infantum associated with HIV. PATIENTS AND METHODS: A 5-year-old boy presented crusted ulcerative lesions of the scalp and left forearm, together with axillary and cervical lymphadenopathy present for two months...
May 3, 2016: Annales de Dermatologie et de Vénéréologie
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