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https://www.readbyqxmd.com/read/29679630/high-irisin-levels-are-associated-with-better-glycemic-control-and-bone-health-in-children-with-type-1-diabetes
#1
Maria Felicia Faienza, Giacomina Brunetti, Lorenzo Sanesi, Graziana Colaianni, Monica Celi, Laura Piacente, Gabriele D'Amato, Ernestina Schipani, Silvia Colucci, Maria Grano
AIM: Irisin is a new peptide produced mainly by the skeletal muscle playing an important role both in glucose/energy homeostasis and bone metabolism. Childhood type 1 diabetes mellitus (T1DM) is associated with decreased bone mass. We aimed to evaluate irisin levels in TD1M children and their correlation with bone metabolism and glycaemic control. METHODS: Ninety-six T1DM subjects (12.2 ± 4 years), 56 on multiple daily injections (MDI), 40 on continuous subcutaneous insulin infusion (CSII), and 34 controls were included in the study...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29674526/galectin-3-downregulates-antioxidant-peroxiredoxin-4-in-human-cardiac-fibroblasts-a-new-pathway-to-induce-cardiac-damage
#2
Jaime Ibarrola, Vanessa Arrieta, Rafael Sádaba, Ernesto Martínez-Martínez, Amaia García-Peña, Virginia Alvarez, Amaya Fernández-Celis, Alicia Gainza, Enrique Santamaría, Joaquin Fernández-Irigoyen, Victoria Cachofeiro, Guillermo Zalba, Renaud Fay, Patrick Rossignol, Natalia López-Andrés
Galectin-3 (Gal-3) is increased in heart failure (HF) and promotes cardiac fibrosis and inflammation. We investigated whether Gal-3 modulates oxidative stress in human cardiac fibroblasts, in experimental animal models and in human aortic stenosis (AS). Using proteomics and immunodetection approaches, we have identified that Gal-3 down-regulated the anti-oxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. In parallel, Gal-3 increased peroxide, nitrotyrosine, malondialdehyde and N-carboxymethyl-lysine levels and decreased total antioxidant capacity...
April 19, 2018: Clinical Science (1979-)
https://www.readbyqxmd.com/read/29664521/-the-association-between-adiposity-and-diabetes-is-modified-by-physical-activity
#3
Ximena Díaz-Martínez, Fanny Petermann, Carlos Salas Bravo, Alex Garrido-Méndez, María Adela Martínez, Ana María Leiva, Cristian Alvarez, Pedro Valdivia-Moral, María Luisa Zagalaz, Eliana Durán, Ana María Labraña, Felipe Poblete-Valderrama, Carlos Celis-Morales
No abstract text is available yet for this article.
November 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29664498/-hypophosphatemia-in-preterm-infants-a-bimodal-disorder
#4
María Paz Cubillos Celis, Patricia Mena Nannig
New nutritional approaches to treat extreme premature babies have demonstrated relevant eviden ce of metabolic disturbances with early hypophosphatemia, especially in patients with intrauterine growth restriction (IUGR). They have shown late hypophosphatemia, as well, which is characteristic in the metabolic bone disease. A sytematic search of literature describing metabolic disturbances of phosphorus in preterm newborns is presented, related to the use of early parenteral nutrition and also in the context of metabolic bone disease...
February 2018: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29655559/associations-between-bone-and-energy-metabolism-in-cows-fed-diets-differing-in-level-of-dietary-cation-anion-difference-and-supplemented-with-cholecalciferol-or-calcidiol
#5
R M Rodney, N P Martinez, P Celi, E Block, P C Thomson, G Wijffels, D R Fraser, J E P Santos, I J Lean
Bone-derived hormones play an important role in metabolism. This study examined the hypothesis that interactions between bone and energy metabolism, particularly those involving osteocalcin, are present in dairy cattle and have feedback mechanisms over time. Associations between metabolites in blood were examined in 32 Holstein cows blocked by parity and milk yield and randomly allocated to diets containing either 0.27 mg/kg dry matter (DM) calcidiol or cholecalciferol for an anticipated intake of 3 mg/d (120,000 IU/d) at 11 kg of DM, and positive (+130 mEq/kg DM) or negative (-130 mEq/kg DM) dietary cation-anion difference (DCAD) from 252 d of gestation to calving...
April 11, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29649077/circulating-cxcr5-expressing-cd8-t-cells-are-major-producers-of-il-21-and-associate-with-limited-hiv-replication
#6
Federico Perdomo-Celis, Natalia A Taborda, Maria T Rugeles
BACKGROUND: Despite advances made with the highly active anti-retroviral therapy (HAART) in the control of the human immunodeficiency virus 1 (HIV) infection, a cure has not been achieved due to the persistence of viral reservoirs. The major HIV reservoirs remain in the lymphoid follicles due to, among other factors, the partial absence of CD8T-cells in these structures. Recently, lymphoid follicle-confined and circulating CD8T-cells expressing the C-X-C chemokine receptor type 5 (CXCR5) were described, possessing antiviral mechanisms which could help to control HIV replication...
April 10, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29625410/exploring-the-influence-of-diels-alder-linker-length-on-photothermal-molecule-release-from-gold-nanorods
#7
Claudia Vetterlein, Rodrigo Vásquez, Karen Bolaños, Gerardo A Acosta, Fanny Guzman, Fernando Albericio, Freddy Celis, Marcelo Campos, Marcelo J Kogan, Eyleen Araya
We studied the photothermal release of carboxyfluorescein (CF) linked to the gold surface of gold nanorods (GNRs) by two Diels-Alder adducts of different lengths (n = 4 and n = 9). The functionalized GNRs were irradiated with infrared light to produce photothermal release of CF by a retro-Diels-Alder reaction. The adducts were chemisorbed on the GNRs and the functionalized nanoparticles were characterized by UV-vis, DLS, zeta potential and Raman and surface-enhanced Raman spectroscopy (SERS). On the basis of the degree of nanoparticle functionalization and the SERS results, we inferred the orientation of CF on the surface of the gold nanoparticle...
March 19, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29624871/utilization-of-aspirin-and-statin-in-management-of-coronary-artery-disease-in-patients-with-cirrhosis-undergoing-liver-transplant-evaluation
#8
Samarth S Patel, Luis Guzman, Fei-Pi Lin, Taylor Pence, Trevor Reichman, Binu John, Francesco S Celi, Erika Liptrap, Chandra Bhati, Mohammad S Siddiqui
Coronary artery disease (CAD) assessment is vital part of liver transplantation (LT) evaluation as it allows for identification and medical optimization prior to transplantation. Although aspirin and statins are standard of care for CAD, they are not universally used in cirrhosis due to concerns of adverse events. METHODS: Per protocol, coronary angiography was performed as part of LT evaluation in all patients over the age of 50 years or with CAD risk factors even if they were younger than 50...
April 6, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29623666/food-tolerance-and-eating-behavior-after-roux-en-y-gastric-bypass-surgery
#9
Cynthia M de A Godoy, Luana Celi Silva Aprígio, Eudes Paiva de Godoy, Mariana Camara Furtado, Daniel Coelho, Lourdes Bernadete Rocha de Souza, Antònio Manuel Goveial de Oliveira
BACKGROUND: Roux-en-Y gastric bypass (RYGB) surgery often leads to food intolerance, especially protein intake. AIM: This is to investigate the association of food intolerance with protein intake and chewing parameters in patients who underwent RYGB surgery 2 years prior. METHODS: An observational study was carried out in 30 patients aged between 18 and 60 years old with at least a 2-year postoperative period since undergoing RYGB surgery...
April 6, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29610308/increased-autophagy-blocks-her2-mediated-breast-tumorigenesis
#10
Silvia Vega-Rubín-de-Celis, Zhongju Zou, Álvaro F Fernández, Bo Ci, Min Kim, Guanghua Xiao, Yang Xie, Beth Levine
Allelic loss of the autophagy gene, beclin 1/BECN1 , increases the risk of patients developing aggressive, including human epidermal growth factor receptor 2 (HER2)-positive, breast cancers; however, it is not known whether autophagy induction may be beneficial in preventing HER2-positive breast tumor growth. We explored the regulation of autophagy in breast cancer cells by HER2 in vitro and the effects of genetic and pharmacological strategies to increase autophagy on HER2-driven breast cancer growth in vivo...
April 2, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29605330/effects-of-nutrition-on-the-fertility-of-lactating-dairy-cattle
#11
R M Rodney, P Celi, W Scott, K Breinhild, J E P Santos, I J Lean
This meta-analysis of 39 experiments containing 118 treatments explored the effects of diet interventions in early lactation on the proportion of dairy cows pregnant to artificial insemination (AI; pregnancy to AI) and on calving to pregnancy interval. It also identified factors that may explain variation in these responses. The objectives were to identify effects of diet on reproduction, rather than differences between specific dietary interventions. The examination of calving to pregnancy interval used the more traditional method of analyzing differences between a treatment and the reference treatment used for comparison within a given experiment...
March 28, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29602439/foreword
#12
EDITORIAL
Leo Anthony Celi, Rodrigo Deliberato, Susana Vieira
No abstract text is available yet for this article.
May 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29601452/hospital-acquired-infections-in-children-a-latin-american-tertiary-teaching-hospital-5-year-experience
#13
Paula Andrade Alvares, Mariana Volpe Arnoni, Cely Barreto da Silva, Marco Aurélio Palazzi Sáfadi, Marcelo Jenné Mimica
Hospital acquired infections account for high mortality rates and hospital costs. We analyzed pediatric data from a tertiary teaching hospital and found that most of cases occurred in the intensive care unit and had significant association with invasive devices. Bloodstream infections were the main site of infection and Gram-negative bacteria were the predominant etiology.
March 29, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29580529/evaluation-of-the-health-benefits-of-consumption-of-extruded-tannin-sorghum-with-unfermented-probiotic-milk-in-individuals-with-chronic-kidney-disease
#14
Rita de Cássia Stampini Oliveira Lopes, Samara Letícia Silva de Lima, Bárbara Pereira da Silva, Renata Celi Lopes Toledo, Maria Eliza de Castro Moreira, Pamella Cristine Anunciação, Eduardo Henrique Miranda Walter, Carlos Wanderlei Piler Carvalho, Valéria Aparecida Vieira Queiroz, Andréia Queiroz Ribeiro, Hércia Stampini Duarte Martino
This study investigated the chemical and nutritional composition of breakfast cereal based on whole sorghum, and the effect of its association with unfermented probiotic milk on the inflammation and oxidative stress of individuals with chronic kidney disease. Extruded sorghum breakfast meal presented higher carbohydrate concentration (approximately 71%), followed by protein (approximately 11%) and lipid (approximately 0.4%). When compared to extruded maize breakfast meal, it presented higher percentage of dietary fiber (p < 0...
May 2018: Food Research International
https://www.readbyqxmd.com/read/29571366/ecophysiological-and-metabolic-responses-to-interactive-exposure-to-nutrients-and-copper-excess-in-the-brown-macroalga-cystoseira-tamariscifolia
#15
Paula S M Celis-Plá, Murray T Brown, Alex Santillán-Sarmiento, Nathalie Korbee, Claudio A Sáez, Félix L Figueroa
Global scenarios evidence that contamination due to anthropogenic activities occur at different spatial-temporal scales, being important stressors: eutrophication, due to increased nutrient inputs; and metal pollution, mostly derived from industrial activities. In this study, we investigated ecophysiological and metabolic responses to copper and nutrient excess in the brown macroalga Cystoseira tamariscifolia. Whole plants were incubated in an indoor system under control conditions, two levels of nominal copper (0...
March 2018: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29566072/behaviour-during-transportation-predicts-stress-response-and-lower-airway-contamination-in-horses
#16
Barbara Padalino, Sharanne L Raidal, Peter Knight, Pietro Celi, Leo Jeffcott, Gary Muscatello
This study aimed to document the effects of an eight hour journey on behavioural, clinical, haematological, environmental and respiratory parameters, and to identify possible associations between factors. Twelve horses underwent clinical examination, respiratory endoscopy with tracheal wash (TW) aspiration, and collection of venous and arterial blood before (BJ) and after the journey (AJ). TW were submitted for conventional quantitative bacteriological evaluation and genetic microbiome analyses. Behaviour was assessed in stables prior to transportation and throughout the journey...
2018: PloS One
https://www.readbyqxmd.com/read/29565165/effect-of-fish-and-olive-oil-on-mitochondrial-atpase-activity-and-membrane-fluidity-in-patients-with-relapsing-remitting-multiple-sclerosis-treated-with-interferon-beta-1-b
#17
Erandis D Torres-Sánchez, Fermín P Pacheco-Moisés, Miguel A Macias-Islas, Eddic W Morales-Sánchez, Viridiana Ramírez-Ramírez, Alfredo J Celis de la Rosa, Margarita Cid-Hernández, Tanya E Sorto-Gómez, Genaro G Ortiz
BACKGROUND: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system associated with increased oxidative stress (OS) and mitochondrial alterations. Fish oil consumption has neuroprotective, antioxidant and anti-inflammatory effects in patients with relapsing-recurrent MS (RR-MS). OBJECTIVE: To evaluate changes in the hydrolytic activity of ATP synthase and mitochondrial membrane fluidity in patients with RR-MS who receive fish oil or olive oil as a dietary supplement...
January 12, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29560555/correction-to-health-related-information-seeking-behaviors-and-preferences-among-mexican-patients-with-cancer
#18
Enrique Soto-Perez-de-Celis, Viridiana Perez-Montessoro, Patricia Rojo-Castillo, Yanin Chavarri-Guerra
The original version of this article unfortunately contained a mistake. The name of "Viridiana Perez-Montessoro" is now corrected in the author group of this article. The original article has been corrected.
March 21, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29557582/inhalation-therapy-in-the-next-decade-determinants-of-adherence-to-treatment-in-asthma-and-copd
#19
Claudio F Donner, Sandro Amaducci, Elena Bacci, Sandra Baldacci, Maria L Bartoli, Gianfranco M Beghi, Alida Benfante, Sara Brighindi, Lucio Casali, Daniela Castiglia, Mario Cazzola, Alessandro Celi, Silvana Cianchetti, Giorgio Colombo, Claudia Crimi, Federico L Dente, Giuseppe Di Maria, Annalisa Di Maria, Manuela Latorre, Federico Lavorini, Sara Maio, Claudia Mannini, Riccardo Messina, Pier Luigi Paggiaro, Patrizia Pignatti, David Price, Nicola Scichilone, Marzia Simoni, Antonio Spanevello, Martina Stagno d'Alcontres, Shawna Tan, Roberto Torchio, Giovanni Viegi, Dina Visca, Emiel F M Wouters, Shaylynn Yu Hui Xin
Proceedings of the European Seminars in Respiratory Medicine course, Inhalation therapy in the next decade: Determinants of adherence to treatment in asthma and COPD, held in Taormina, Italy, on 3-4 March, 2017.
February 2, 2018: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/29556931/effectiveness-and-security-of-chronic-hepatitis-c-treatment-in-coinfected-patients-in-real-world
#20
Moisés Uriarte-Pinto, Herminia Navarro-Aznarez, Natalia De La Llama-Celis, Piedad Arazo-Garcés, Ana María Martínez-Sapiña, María Reyes Abad-Sazatornil
Background HIV-HCV coinfection produces high morbi-mortality. Direct-acting antivirals (DAAs) have shown high efficacy, although special attention should be paid to the risk of drug interactions. However, due to the lack of representativeness of coinfected patients in clinical trials, it is important to know real-world results. Objective To evaluate DAA treatment effectiveness in coinfected patients. We also analyse safety profile of DAA treatment and drug interactions between HCV and HIV therapy. Setting Descriptive study carried in a tertiary hospital of Spain Method HIV-HCV coinfected patients treated with DAAs between November 2014 and June 2016 were included...
March 20, 2018: International Journal of Clinical Pharmacy
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