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E I Vanguelova, E Bonifacio, B De Vos, M R Hoosbeek, T W Berger, L Vesterdal, K Armolaitis, L Celi, L Dinca, O J Kjønaas, P Pavlenda, J Pumpanen, Ü Püttsepp, B Reidy, P Simončič, B Tobin, M Zhiyanski
Spatially explicit knowledge of recent and past soil organic carbon (SOC) stocks in forests will improve our understanding of the effect of human- and non-human-induced changes on forest C fluxes. For SOC accounting, a minimum detectable difference must be defined in order to adequately determine temporal changes and spatial differences in SOC. This requires sufficiently detailed data to predict SOC stocks at appropriate scales within the required accuracy so that only significant changes are accounted for...
November 2016: Environmental Monitoring and Assessment
Flávia Morais Gomes Pinto, Camila Quartim de Moraes Bruna, Tamara Carolina Camargo, Maíra Marques, Cely Barretos Silva, Suzete M Sasagawa, Lycia Maria Jenné Mimica, Kazuko Uchikawa Graziano
A high-speed handpiece is used in several dental procedures and the official recommendation for safe decontamination consists of rinsing with water, washing with detergent, mechanical friction, and sterilization; however, many professionals only apply 70% w/v alcohol without also cleaning the tool between patients. We performed an analysis of high-speed handpieces reprocessed only with 70% w/v alcohol and found that the methods used in clinical practice are not safe.
October 18, 2016: American Journal of Infection Control
Cinzia Niolu, Emanuela Bianciardi, Giorgio Di Lorenzo, Sara Nicolai, Monica Celi, Michele Ribolsi, Adalgisa Pietropolli, Carlo Ticconi, Umberto Tarantino, Alberto Siracusano
RIASSUNTO. Introduzione. La depressione maggiore (MD) e l'osteoporosi sono malattie ad alta prevalenza nel genere femminile, associate a morbosità e mortalità. Sebbene alcuni studi abbiano dimostrato un'associazione tra MD, ridotta densità minerale ossea (BMD) e osteoporosi, non sono stati chiariti i meccanismi causali. Lo stile di attaccamento insicuro è stato messo in relazione con la patogenesi e il decorso di malattie croniche come la MD e le malattie cardiovascolari. Obiettivo di questo studio pilota è esplorare la relazione tra MD e BMD...
July 2016: Rivista di Psichiatria
T Cifuentes, J Cayupi, C Celis-Barros, G Zapata-Torres, Rafael Ballesteros, Rafael Ballesteros-Garrido, B Abarca, C Jullian
The inclusion complexation behavior of 3-(2-thienyl)-[1,2,3]triazolo[1,5-a] pyridine (TTP) with native β-cyclodextrin and derivatized cyclodextrins was investigated. Stability constants for complexes with 1 : 1 molar ratios were calculated from phase solubility diagrams. The solubilizing efficiency of the TTP inclusion complex is enhanced in the order of DMβCD > HPβCD > βCD. The TTP-DMβCD inclusion complex was further characterized in solution by means of absorption, fluorescence, 2D NMR and molecular modeling methods...
October 18, 2016: Organic & Biomolecular Chemistry
Clare B O'Donovan, Marianne C Walsh, Hannah Forster, Clara Woolhead, Carlos Celis-Morales, Rosalind Fallaize, Anna L Macready, Cyril F M Marsaux, Santiago Navas-Carretero, Rodrigo San-Cristobal, Silvia Kolossa, Christina Mavrogianni, Christina P Lambrinou, George Moschonis, Magdalena Godlewska, Agnieszka Surwillo, Jildau Bouwman, Keith Grimaldi, Iwona Traczyk, Christian A Drevon, Hannelore Daniel, Yannis Manios, J Alfredo Martinez, Wim H M Saris, Julie A Lovegrove, John C Mathers, Michael J Gibney, Lorraine Brennan, Eileen R Gibney
BACKGROUND: It is hypothesised that individuals with knowledge of their genetic risk are more likely to make health-promoting dietary and lifestyle changes. The present study aims to test this hypothesis using data from the Food4Me study. This was a 6-month Internet-based randomised controlled trial conducted across seven centres in Europe where individuals received either general healthy eating advice or varying levels of personalised nutrition advice. Participants who received genotype-based personalised advice were informed whether they had the risk (CT/TT) (n = 178) or non-risk (CC) (n = 141) alleles of the methylenetetrahydrofolate reductase (MTHFR) gene in relation to cardiovascular health and the importance of a sufficient intake of folate...
2016: Genes & Nutrition
Mike Wu, Marzyeh Ghassemi, Mengling Feng, Leo A Celi, Peter Szolovits, Finale Doshi-Velez
BACKGROUND: The widespread adoption of electronic health records allows us to ask evidence-based questions about the need for and benefits of specific clinical interventions in critical-care settings across large populations. OBJECTIVE: We investigated the prediction of vasopressor administration and weaning in the intensive care unit. Vasopressors are commonly used to control hypotension, and changes in timing and dosage can have a large impact on patient outcomes...
October 5, 2016: Journal of the American Medical Informatics Association: JAMIA
Katherine M Livingstone, Carlos Celis-Morales, Ulrich Hoeller, Christina P Lambrinou, George Moschonis, Anna L Macready, Rosalind Fallaize, Manuela Baur, Franz F Roos, Igor Bendik, Keith Grimaldi, Santiago Navas-Carretero, Rodrigo San-Cristobal, Peter Weber, Christian A Drevon, Yannis Manios, Iwona Traczyk, Eileen R Gibney, Julie A Lovegrove, Wim H Saris, Hannelore Daniel, Mike Gibney, J Alfredo Martinez, Lorraine Brennan, Tom R Hill, John C Mathers
SCOPE: Little is known about diet- and environment-gene interactions on 25-hydroxyvitamin D (25(OH)D concentration. This cross-sectional study aimed to investigate i) predictors of 25(OH)D concentration and relationships with vitamin D genotypes and ii) whether dietary vitamin D intake and sunlight exposure modified these relationships. METHODS AND RESULTS: Participants from the Food4Me study (n = 1312; age 18-79) were genotyped for vitamin D receptor (VDR) and vitamin D binding protein at baseline and a genetic risk score was calculated...
September 28, 2016: Molecular Nutrition & Food Research
B Padalino, S L Raidal, E Hall, P Knight, P Celi, L Jeffcott, G Muscatello
OBJECTIVE: To survey amateur and professional participants on equine transportation management, practices and outcomes in Australia. METHODS: An online survey targeting people who organised horse movements at least monthly was made available to a broad cross-section of amateur and professional equine associations. Respondents were invited to provide demographic details and information relating to their routine transportation management practices and their experiences of issues relating to the transportation of horses...
October 2016: Australian Veterinary Journal
Barret Rush, Kali Romano, Mohammad Ashkanani, Robert C McDermid, Leo Anthony Celi
OBJECTIVE: There have been suggestions that patients with subarachnoid hemorrhage (SAH) have a better outcome when treated in high-volume centers. Much of the published literature on the subject is limited by an inability to control for severity of SAH. METHODS: This is a nationwide retrospective cohort analysis using the Nationwide Inpatient Sample (NIS). The NIS Subarachnoid Severity Scale was used to adjust for severity of SAH in multivariate logistic regression modeling...
September 14, 2016: Journal of Critical Care
Katherine M Livingstone, Carlos Celis-Morales, George D Papandonatos, Bahar Erar, Jose C Florez, Kathleen A Jablonski, Cristina Razquin, Amelia Marti, Yoriko Heianza, Tao Huang, Frank M Sacks, Mathilde Svendstrup, Xuemei Sui, Timothy S Church, Tiina Jääskeläinen, Jaana Lindström, Jaakko Tuomilehto, Matti Uusitupa, Tuomo Rankinen, Wim H M Saris, Torben Hansen, Oluf Pedersen, Arne Astrup, Thorkild I A Sørensen, Lu Qi, George A Bray, Miguel A Martinez-Gonzalez, J Alfredo Martinez, Paul W Franks, Jeanne M McCaffery, Jose Lara, John C Mathers
OBJECTIVE:  To assess the effect of the FTO genotype on weight loss after dietary, physical activity, or drug based interventions in randomised controlled trials. DESIGN:  Systematic review and random effects meta-analysis of individual participant data from randomised controlled trials. DATA SOURCES:  Ovid Medline, Scopus, Embase, and Cochrane from inception to November 2015. ELIGIBILITY CRITERIA FOR STUDY SELECTION:  Randomised controlled trials in overweight or obese adults reporting reduction in body mass index, body weight, or waist circumference by FTO genotype (rs9939609 or a proxy) after dietary, physical activity, or drug based interventions...
2016: BMJ: British Medical Journal
Guilherme Akio Tamura Ozaki, Regina Celi Trindade Camargo, Tatiana Emy Koike, Thiago Alves Garcia, Robson Chacon Castoldi, João Domingos Augusto Dos Santos Pereira, Carlos José Leopoldo Constantino, José Carlos Silva Camargo Filho
Treatment of muscle injuries usually results in the interruption of sports practice; thus, studies aimed at accelerating the return to activity, with proper tissue repair, are important. Therefore, this study aimed to evaluate the effects of photobiomodulation (PBM), associated or not with platelet-rich plasma (PRP), on the treatment of muscle injury. Thirty-five animals were used and divided into five groups (n = 7): control (C), control lesion (CL), lesion treated with low-level laser therapy (LLLT) (LLt), lesion treated with PRP (LP), and lesion treated with both techniques, LLLT and PRP (LLtP)...
September 20, 2016: Lasers in Medical Science
Miguel Germán Borda, Carlos Andrés Celis-Preciado, Mario Ulises Pérez-Zepeda, Julián David Ríos-Zuluaga, Carlos Alberto Cano-Gutiérrez
INTRODUCTION: It has been reported that sarcopenia frequently co-exists with COPD/asthma, and can significantly affect quality of life and the control of chronic diseases. The aim of this study is to describe the association between COPD/asthma and sarcopenia. MATERIAL AND METHODS: Data was used from the SABE-Bogotá study, which included 2,000 older adults aged 60 years or more. It is a cross-probabilistic cluster sample with 81.9% coverage. The dependent variable was COPD/asthma...
September 14, 2016: Revista Española de Geriatría y Gerontología
Charlotte Steenblock, Maria F Rubin de Celis, Andreas Androutsellis-Theotokis, Mariko Sue, Luis F Delgadillo Silva, Graeme Eisenhofer, Cynthia L Andoniadou, Stefan R Bornstein
The adrenal gland is a highly plastic organ with the capacity to adapt the body homeostasis to different physiological needs. The existence of stem-like cells in the adrenal cortex has been revealed in many studies. Recently, we identified and characterized in mice a pool of glia-like multipotent Nestin-expressing progenitor cells, which contributes to the plasticity of the adrenal medulla. In addition, we found that these Nestin progenitors are actively involved in the stress response by giving rise to chromaffin cells...
September 13, 2016: Molecular and Cellular Endocrinology
Trang N Le, Francesco S Celi, Edmond P Wickham
BACKGROUND: Increased thyrotropin (TSH) levels and free triiodothyronine to free thyroxine (fT3:fT4) ratios, even within the euthyroid range, have been associated with cardiometabolic risk factors in adults but are less characterized in youth. This study sought to determine relations between TSH, thyroid hormones, and cardiometabolic risk factors in euthyroid adolescents. METHODS: Data were extracted from the United States National Health and Nutrition Examination Survey, 2007-2010, for univariate and multivariate analyses of TSH, thyroid hormones, body mass index (BMI), blood pressure, lipids, and glucose metabolism...
October 2016: Thyroid: Official Journal of the American Thyroid Association
Josephus G Buijnsters, Menelaos Tsigkourakos, Thomas Hantschel, Francis O V Gomes, Thomas Nuytten, Paola Favia, Hugo Bender, Kai Arstila, Jean-Pierre Celis, Wilfried Vandervorst
B-doped diamond has become the ultimate material for applications in the field of microelectromechanical systems (MEMS), which require both highly wear resistant and electrically conductive diamond films and microstructures. Despite the extensive research of the tribological properties of undoped diamond, to date there is very limited knowledge of the wear properties of highly B-doped diamond. Therefore, in this work a comprehensive investigation of the wear behavior of highly B-doped diamond is presented. Reciprocating sliding tests are performed on micro- and nanocrystalline diamond (MCD, NCD) films with varying B-doping levels and thicknesses...
October 5, 2016: ACS Applied Materials & Interfaces
Francisco Calderón-Celis, Silvia Diez-Fernández, José Manuel Costa-Fernández, Jorge Ruiz Encinar, Juan J Calvete, Alfredo Sanz-Medel
Absolute protein quantification methods based on molecular mass spectrometry usually require stable isotope-labeled analogous standards for each target protein or peptide under study, which in turn must be certified using natural standards. In this work, we report a direct and accurate methodology based on capLC-ICP-QQQ and online isotope dilution analysis for the absolute and sensitive quantification of intact proteins. The combination of the postcolumn addition of (34)S and a generic S-containing internal standard spiked to the sample provides full compound independent detector response and thus protein quantification without the need for specific standards...
October 4, 2016: Analytical Chemistry
Barbara Padalino, Sharanne L Raidal, Evelyn Hall, Peter Knight, Pietro Celi, Leo Jeffcott, Gary Muscatello
An online survey was conducted to determine associations between transport management and transport-related injuries and diseases in horses in Australia. The survey was composed of three sections: respondents' demographic information, transport management strategies or procedures (before, during and after transportation) and transport diseases experienced in the previous two year period. Univariate and multivariate modelling was performed exploring associations between variables (respondents' details and transport management strategies) and the following transport-related diseases as outcomes: traumatic injuries, diarrhoea, heat stroke, muscular problems, laminitis, transport pneumonia and colic...
2016: PloS One
Takumi Kumai, Esteban Celis, Paulo C Rodriguez
No abstract text is available yet for this article.
September 2016: Journal of Leukocyte Biology
Dario Nieri, Tommaso Neri, Silvia Petrini, Barbara Vagaggini, Pierluigi Paggiaro, Alessandro Celi
Cell-derived microparticles are small (0.1-1 μm) vesicles shed by most eukaryotic cells upon activation or during apoptosis. Microparticles carry on their surface, and enclose within their cytoplasm, molecules derived from the parental cell, including proteins, DNA, RNA, microRNA and phospholipids. Microparticles are now considered functional units that represent a disseminated storage pool of bioactive effectors and participate both in the maintenance of homeostasis and in the pathogenesis of diseases. The mechanisms involved in microparticle generation include intracellular calcium mobilisation, cytoskeleton rearrangement, kinase phosphorylation and activation of the nuclear factor-κB...
September 2016: European Respiratory Review: An Official Journal of the European Respiratory Society
B Padalino, S L Raidal, E Hall, P Knight, P Celi, L Jeffcott, G Muscatello
BACKGROUND: Transportation can affect equine health and is a potential source of economic loss to the industry. OBJECTIVES: To identify journey (duration, vehicle, commercial or noncommercial) and horse (sex, age, breed, use, amateur or professional status) characteristics associated with the development of transport-related health problems in horses. STUDY DESIGN: Cross-sectional online survey. METHODS: An online survey was conducted targeting amateur and professional participants in the Australian equine industry; eligible respondents were required to organise horse movements at least monthly...
August 26, 2016: Equine Veterinary Journal
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