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pyogenic liver abscess

Coeway Boulder Thng, Yen Pin Tan, Vishal G Shelat
Backgrounds/Aims: Gas-forming pyogenic liver abscess (GFPLA) has an incidence of up to 30% of all pyogenic liver abscesses (PLA). GFPLA has higher mortality compared to non-GFPLA. Mere presence of gas within abscess may not determine clinical outcome. Hence it is important to study biologic characteristics that make GFPLA a distinct clinical entity. The aim of this study was to conduct a world review on GFPLA. Methods: We conducted literature searches in PubMed using the following MeSH terms: "gas forming" AND "Liver abscess, pyogenic", "gas" AND "Liver abscess, pyogenic", "gas" AND "Liver abscess", "gas forming" AND "Liver abscess"...
February 2018: Annals of Hepato-Biliary-Pancreatic Surgery
Kazuhiko Morii, Takeharu Yamamoto, Shinichiro Nakamura, Hiroaki Okushin
Objective An infectious hepatic cyst (IHC) is a hepatic cyst complicated with secondary infection and is generally assumed to be rare. However, we have experienced no small number of patients with IHC in recent clinical practice. We therefore examined the incidence and clinical characteristics of IHC. Methods The medical records of patients with IHC who were hospitalized at our institution between January 2012 and December 2016 were retrospectively reviewed. Their demographic factors, biochemical, bacteriological, imaging, and treatment results were explored and compared with those of patients with pyogenic liver abscess (PLA)...
March 9, 2018: Internal Medicine
Kazuhiko Morii, Shigeyoshi Fujiwara, Shinichiro Nakamura, Hiroaki Okushin
No abstract text is available yet for this article.
March 9, 2018: Internal Medicine
Yen-Chun Peng, Cheng-Li Lin, Fung-Chang Sung
OBJECTIVES: To evaluate the risk of pyogenic liver abscess (PLA) in patients receiving endoscopic sphincterotomy (ES). SETTING: A population-based cohort study using data from Taiwans' National Health Insurance Research Database was conducted. Patients aged 20 or older who had undergone an ES were considered as the ES cohort. The dates for the first hospitalisation of the patients receiving ES were defined as the index dates. PARTICIPANTS: Patients in the ES and non-ES cohorts were selected by 1:1 matching ratio based on a propensity score...
March 3, 2018: BMJ Open
Matias E Czerwonko, Pablo Huespe, Cristina M Elizondo, Juan Pekolj, Adrian Gadano, Laura Barcán, Sung-Ho Hyon, Eduardo de Santibañes, Martín de Santibañes
BACKGROUND: Adult liver recipients (ALR) differ from the general population with pyogenic liver abscess (PLA) as they exhibit: reconstructed biliary anatomy, recurrent hospitalizations, poor clinical condition and are subjected to immunosuppression. The aim of this study was to identify risk factors associated with PLA in ALR and to analyze the management experience of these patients. METHODS: Between 1996 and 2016, 879 adult patients underwent liver transplantation (LT), 26 of whom developed PLA...
February 26, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
Liang Zhang, DaLong Wan, LeLe Zhang, ShiGuo Xu, HaiYang Xie, ShengZhang Lin
RATIONALE: Currently, percutaneous catheter drainage (PCD) is regarded as the first-line treatment modality of pyogenic liver abscess. Severe complications associated with PCD were uncommon. Hepatic rupture is an uncommon but life-threatening liver trauma with high mortality. Its management is challenging because a delay in the diagnosis may lead to fatal hemorrhagic shock. To our knowledge, PCD-associated hepatic rupture has never been reported. PATIENT CONCERNS: We report herein a rare case of PCD-associated hepatic rupture...
January 2018: Medicine (Baltimore)
Shih-Wei Lai, Cheng-Li Lin, Kuan-Fu Liao
BACKGROUND AND AIM: There are no epidemiological studies focusing on the association between oral corticosteroid use and pyogenic liver abscesses. The aim of the study was to assess whether oral corticosteroid use is associated with increased odds of pyogenic liver abscesses in adults in Taiwan. METHODS: This retrospective population-based case-control study was conducted to analyze the database of the Taiwan National Health Insurance Program from 2000 to 2013. Subjects aged 20 to 84 years with their first episode of pyogenic liver abscesses were assigned as the cases (n = 881)...
March 2018: BioMedicine
Kwang Soon Park, Sun Hwa Lee, Seong Jong Yun, Seokyong Ryu, Keon Kim
PURPOSE: The neutrophil-to-lymphocyte ratio (NLR) is an effective predictor of mortality in patients with for various conditions. To date, there are no previous studies on NLR as a prognostic marker for pyogenic liver abscess (PLA), especially on admission to the emergency department (ED). METHODS: From January 2013 to December 2015, 102 patients diagnosed with PLA in the ED were included. Clinico-radiological and laboratory results, including NLR, were evaluated as variables...
February 26, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
Raúl Recio, Patricia Brañas, Fernando Chaves, M Ángeles Orellana
No abstract text is available yet for this article.
March 2018: Journal of Clinical Microbiology
Rebekah M Martin, Michael A Bachman
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae strains into opportunistic, hypervirulent, and multidrug-resistant groups and separates K. pneumoniae from two closely related species, Klebsiella variicola and Klebsiella quasipneumoniae. Some strains of K. pneumoniae act as opportunistic pathogens, infecting critically ill and immunocompromised patients. These K. pneumoniae are a common cause of health-care associated infections including pneumonia, urinary tract infections (UTIs), and bloodstream infections...
2018: Frontiers in Cellular and Infection Microbiology
Lihua Deng, Rong Jia, Wei Li, Qian Xue, Jie Liu, Yide Miao, Jingtong Wang
RATIONALE: Rhabdomyolysis is a well-known syndrome in clinical practice, although rhabdomyolysis caused by a liver abscess is rarely reported and the patient may lack symptoms that are associated with a primary site of infection. Early recognition of this possibility is needed to avoid diagnostic delay and facilitate treatment. We report the case of a 71-year-old woman with a Klebsiella pneumoniae (KP) pyogenic liver abscess who presented with myasthenia and tea-colored urine and also review the 77 reported cases of bacterial rhabdomyolysis...
December 2017: Medicine (Baltimore)
Ting Huang, Xuhao Song, Jie Jing, Kelei Zhao, Yongmei Shen, Xiuyue Zhang, Bisong Yue
BACKGROUND: Trueperella pyogenes is a commensal and opportunistic pathogen that normally causes mastitis, liver abscesses and pneumonia of economically important livestock. To develop efficacious and potent vaccine against T. pyogenes, chimeric gene DNA vaccines were constructed and encapsulated in chitosan nanoparticles (pPCFN-CpG-CS-NPs). RESULTS: The pPCFN-CpG-CS-NPs consists of the plo, cbpA, fimA, and nanH gene of T. pyogenes and CpG ODN1826. It was produced with good morphology, high stability, a mean diameter of 93...
January 29, 2018: Journal of Nanobiotechnology
Kyung Jin Lee, Soo Hyung Ryu
Gas-forming pyogenic liver abscess (GFPLA) is very rare and has a very high mortality in case of rupture into the abdominal cavity, which usually require surgical treatment. We experienced a case of a ruptured GFPLA due to Klebsiella pneumoniae complicated with peritonitis and sepsis in a 68-year-old diabetic woman. Immediate and aggressive medical treatments including intravenous antibiotics, percutaneous drainage, and continuous renal replacement therapy dramatically improved the liver abscess, peritonitis, and metabolic problems...
January 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
Eunae Cho, Sang Woo Park, Chung Hwan Jun, Sang Soo Shin, Eun Kyu Park, Kyo Seon Lee, Seon Young Park, Chang Hwan Park, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
BACKGROUND: Transdiaphragmatic extension of pyogenic liver abscess is the rarest cause of pericarditis and pleural empyema. It is a rapidly progressive and highly lethal infection with mortality rates reaching 100% if left untreated. However, the transmission route, treatment methods and prognosis have not been well studied. CASE PRESENTATION: A 65-year-old male patient presented with a fever, dyspnea, and right upper quadrant abdominal pain. Computed tomography of the chest and abdomen showed huge liver abscess without full liquefaction in the left lobe, large amount of left pleural effusion, and mild pericardial effusion, and the patient was treated with parenteral antibiotics and pigtail insertion at the left pleura...
January 15, 2018: BMC Infectious Diseases
Anne Christine Nordholm, Ruth Ottilia Birgitta Vøgg, Henrik Permin, Terese Katzenstein
BACKGROUND: Eikenella corrodens is one of the HACEK bacteria constituting part of the normal flora of the oropharynx, however, still an uncommon pathogen. We report a case of a large Eikenella corrodens liver abscess with simultaneously endocarditis in a previously healthy male. CASE PRESENTATION: A 49-year-old Danish man was admitted because of one-month malaise, fever, cough and unintentional weight loss. On admission there was elevated white blood cell count and C-reactive protein, as well as affected liver function tests...
January 12, 2018: BMC Infectious Diseases
D Bettinger, D Martin, S Rieg, M Schultheiss, N Buettner, R Thimme, T Boettler
BACKGROUND: Proton pump inhibitors (PPI) are often used in patients with gastro-esophageal reflux and peptic ulcer disease. A higher risk for infectious diseases and for pyogenic liver abscess has been reported in patients with prolonged PPI intake. Although many patients have ongoing PPI treatment after diagnosis of liver abscess, there are no data available that focus on the prognostic impact of PPI treatment in these patients. AIM: To analyse the effect of PPI treatment on mortality in patients with pyogenic liver abscesses...
January 12, 2018: Alimentary Pharmacology & Therapeutics
Marina Gorelik, Braulio Sabates, Adel Elkbuli, Tony Dunne
INTRODUCTION: Small intestine gastrointestinal stromal tumors can infrequently present with intra-abdominal abscess, perforation, obstruction or fistula. Tumor-small intestine fistula is a rare phenomenon and occurs as a result of GISTs' propensity to cause mucosal ulceration. This allows bacteria from the gut to gain access to the systemic circulation and predisposes the patient to bacteremia and pyogenic liver abscess. PRESENTATION OF CASE: We present a case of a 63-year-old female whose initial symptoms included fever, nausea, vomiting and right upper quadrant pain...
December 27, 2017: International Journal of Surgery Case Reports
Sunite A Ganju, Neha Gautam, Garima Sharma
Streptococcus anginosus forms a part of the commensal flora of the oral cavity. However, it can be aggressive and may lead to gastrointestinal and urogenital infections. We present an interesting case and course in a 38-year-old immunocompetent female patient with pyogenic liver abscess due to S. anginosus infection who had multiple carious teeth and underlying pulmonary tuberculosis.
October 2017: Indian Journal of Pathology & Microbiology
Prashanth Rawla, Anantha R Vellipuram, Sathyajit S Bandaru, Jeffrey Pradeep Raj
A collection of dead white blood cells within the liver is called a liver abscess, and pyogenic liver abscess (PLA) is the most common type. PLA is commonly associated with biliary tract infections. However, in this case report, we present a rare cause of Streptococcus anginosus bacteremia and PLA which is associated with a carcinoma of the colon at the splenic flexure. The presentation mimicked a cholecystitis clinically, but the radio-imaging revealed a liver abscess. Blood cultures revealed an uncommon etiological agent, S...
December 2017: Gastroenterology Research
Renato G Bandeira-de-Mello, Gabriel Bondar, Eduardo Schneider, Isabel Cristina Wiener-Stensmann, Juliano Bohrer Gressler, Cleber Rosito Pinto Kruel
Liver abscess due to perforation of the gastrointestinal tract by a foreign body is a rare and possibly fatal event. Diagnosing this pathology is complicated by the lack of specific symptoms and unfamiliarity of ingestion by the patient and low clinical suspicion of this disease. In the case of liver abscess unresponsive to aspiration and administration of antibiotics, this hypothesis must be made, despite its low incidence. This case report describes and illustrates a case of liver abscess secondary to fish bone ingestion with consequent piercing of the lesser gastric curvature, diagnosed by computed tomography and specific anamnesis...
January 2018: Annals of Hepatology
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