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https://www.readbyqxmd.com/read/28269226/a-morphological-approach-to-detect-respiratory-phases-of-seismocardiogram
#1
N Alamdari, K Tavakolian, V Zakeri, R Fazel-Rezai, A Akhbardeh
This paper presents a new approach to identify the respiratory phases of heart cycles from acceleration signals (i.e., seismocardiogram) recorded from the sternum, in back to front direction. The acceleration signals were recorded simultaneously with a single lead electrocardiogram (ECG), and the respiratory signal (using a chest band strain gauge) from 20 healthy subjects. Two accelerometer-derived respiration (ADR) signals were computed by computing the lower and upper envelope of the accelerometer signal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227456/a-morphological-approach-to-detect-respiratory-phases-of-seismocardiogram
#2
N Alamdari, K Tavakolian, V Zakeri, R Fazel-Rezai, A Akhbardeh, N Alamdari, K Tavakolian, V Zakeri, R Fazel-Rezai, A Akhbardeh, V Zakeri, N Alamdari, K Tavakolian, R Fazel-Rezai, A Akhbardeh
This paper presents a new approach to identify the respiratory phases of heart cycles from acceleration signals (i.e., seismocardiogram) recorded from the sternum, in back to front direction. The acceleration signals were recorded simultaneously with a single lead electrocardiogram (ECG), and the respiratory signal (using a chest band strain gauge) from 20 healthy subjects. Two accelerometer-derived respiration (ADR) signals were computed by computing the lower and upper envelope of the accelerometer signal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28198909/luminescent-ybvo4-by-atomic-layer-deposition
#3
Michael Getz, Per-Anders Hansen, Mohammed A K Ahmed, Helmer Fjellvåg, Ola Nilsen
UV to visible and near-infrared converting thin films of YbVO4 have been deposited by atomic layer deposition, using the precursor combinations Yb(thd)3 (thd = 2,2,6,6-tetramethyl-3,5-heptanedione) and O3, and VO(thd)2 and O3 at a deposition temperature of 240 °C, followed by post deposition annealing at 400-1000 °C. The UV absorption and the visible and near-infrared emission have been investigated in detail. The structure, thickness and composition of the deposited films have been studied by X-ray diffraction, ellipsometry, and X-ray fluorescence, respectively...
February 15, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28192436/an-improved-synchronous-reference-frame-current-control-strategy-for-a-photovoltaic-grid-connected-inverter-under-unbalanced-and-nonlinear-load-conditions
#4
Amirreza Naderipour, Abdullah Asuhaimi Mohd Zin, Mohd Hafiz Bin Habibuddin, Mohammad Reza Miveh, Josep M Guerrero
In recent years, renewable energy sources have been considered the most encouraging resources for grid and off-grid power generation. This paper presents an improved current control strategy for a three-phase photovoltaic grid-connected inverter (GCI) under unbalanced and nonlinear load conditions. It is challenging to suppress the harmonic content in the output current below a pre-set value in the GCI. It is also difficult to compensate for unbalanced loads even when the grid is under disruption due to total harmonic distortion (THD) and unbalanced loads...
2017: PloS One
https://www.readbyqxmd.com/read/28000010/two-cases-demonstrating-thalidomide-s-efficacy-in-refractory-lupus-nephritis
#5
REVIEW
Rita Raturi, Avani A Patel, John D Carter
Renal involvement in systemic lupus erythematosus (SLE) is common and has been associated with an increased risk of mortality [1]. Early diagnosis is imperative to control proteinuria and prevent the progression to end-stage renal disease. Standard induction therapies include cyclophosphamide (CYC) and mycophenolate mofetil (MMF); however, it has been estimated that approximately 30% of patients are refractory to these standard treatments after 1 year [2]. We present two cases of patients diagnosed with lupus nephritis (LN) who demonstrated persistent proteinuria while on standard treatments that markedly improved after addition of thalidomide (THD)...
March 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/27977169/modulating-single-molecule-magnetic-behavior-of-a-dinuclear-erbium-iii-complex-by-solvent-exchange
#6
Jing-Yuan Ge, Long Cui, Jing Li, Fei Yu, You Song, Yi-Quan Zhang, Jing-Lin Zuo, Mohamedally Kurmoo
[Er2(thd)4Pc]·2C6H6 (1) (Hthd = 2,2,6,6-tetramethylheptanedione), obtained as green crystals from the reaction of [Er(thd)3]·2H2O with lithium phthalocyanine, Li2Pc, is a stable dinuclear complex with two Er(III) centers. Its lattice benzene solvent can be exchanged by soaking the crystals in dichloromethane to give [Er2(thd)4Pc]·2CH2Cl2 (2). The magnetic susceptibility data suggest different coupling interactions for the two complexes. While 1 exhibits fast relaxation and an estimated energy barrier of Ea = 2...
January 3, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/27915573/solid-dispersions-enhance-solubility-dissolution-and-permeability-of-thalidomide
#7
Silvana A Barea, Cristiane B Mattos, Ariadne C C Cruz, Vitor C Chaves, Rafael N Pereira, Claudia M O Simões, Jadel M Kratz, Letícia S Koester
Thalidomide (THD) is a BCS class II drug with renewed and growing therapeutic applicability. Along with the low aqueous solubility, additional poor biopharmaceutical properties of the drug, i.e. chemical instability, high crystallinity, and polymorphism, lead to a slow and variable oral absorption. In this view, we developed solid dispersions (SDs) containing THD dispersed in different self-emulsifying carriers aiming at an enhanced absorption profile for the drug. THD was dispersed in lauroyl macrogol-32 glycerides (Gelucire(®) 44/14) and α-tocopherol polyethylene glycol succinate (Kolliphor(®) TPGS), in the presence or absence of the precipitation inhibitor polyvinylpyrrolidone K30 (PVP K30), by means of the solvent method...
March 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/27901073/thd-module-extractor-an-application-for-cen-module-extraction-and-interesting-gene-identification-for-alzheimer-s-disease
#8
Tulika Kakati, Hirak Kashyap, Dhruba K Bhattacharyya
There exist many tools and methods for construction of co-expression network from gene expression data and for extraction of densely connected gene modules. In this paper, a method is introduced to construct co-expression network and to extract co-expressed modules having high biological significance. The proposed method has been validated on several well known microarray datasets extracted from a diverse set of species, using statistical measures, such as p and q values. The modules obtained in these studies are found to be biologically significant based on Gene Ontology enrichment analysis, pathway analysis, and KEGG enrichment analysis...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27888438/transanal-hemorrhoidal-dearterialization-with-mucopexy-versus-open-hemorrhoidectomy-in-the-treatment-of-hemorrhoids-a-meta-analysis-of-randomized-control-trials
#9
L Xu, H Chen, G Lin, Q Ge, H Qi, X He
BACKGROUND: The aim of this study was to analyse the outcomes of transanal hemorrhoidal dearterialization with mucopexy (THDm) versus open hemorrhoidectomy (OH) in the management of hemorrhoids. METHODS: Randomized controlled trials in English were found by searching PubMed, Web of science, EMBASE, and the Cochrane Library database. Trials that compared THDm with OH were identified. Data were extracted independently for each study, and a meta-analysis was performed using fixed and random effects models...
December 2016: Techniques in Coloproctology
https://www.readbyqxmd.com/read/27860474/-phenolic-compounds-in-leaves-insertions-of-mentha-%C3%A3-villosa-huds-cv-sne%C3%A5-n%C3%A3
#10
Daniela Tekeľová, Silvia Bittner Fialová, Jaroslav Tóth, Szilvia Czigle
Lamiaceae plants mostly accumulate active ingredients in their leaves. The subfamily Nepetoideae, including the genus Mentha L., is characterized by the presence of essential oil and antioxidant phenolics, chiefly hydroxycinnamic acids with predominance of rosmarinic acid, and flavonoids. Mentha × piperita and M. spicata are the most broadly used mints in both medicine and industry, while M. x villosa is less known in our country. Herbal drugs in the form of leaves are usually analysed unpartitioned, while single leaves insertions have only been studied occasionally...
2016: Ceská a Slovenská Farmacie
https://www.readbyqxmd.com/read/27813396/stapled-anopexy-versus-transanal-hemorrhoidal-dearterialization-for-hemorrhoidal-disease-a-three-year-follow-up-from-a-randomized-study
#11
Marco Venturi, Giovanni Salamina, Contardo Vergani
BACKGROUND: This randomized study compared the medium-term results of stapled anopexy (SA) and transanal hemorrhoidal dearterialization with anopexy (THD) in 4 homogeneous groups of patients, 2 with third- and 2 with fourth-degree hemorrhoids. METHODS: Forty patients with third-degree and 30 with fourth-degree hemorrhoids were randomly submitted to SA (N.=20+15) and THD (N.=20+15), respectively. Clinical controls were done every 6 months from 1 to 42 months after the operation, with incidence of recurrent hemorrhoids as primary outcome measure...
December 2016: Minerva Chirurgica
https://www.readbyqxmd.com/read/27803165/g%C3%AE-13-switch-region-2-relieves-talin-autoinhibition-to-activate-%C3%AE-iib%C3%AE-3-integrin
#12
James Schiemer, Andrew Bohm, Li Lin, Glenn Merrill-Skoloff, Robert Flaumenhaft, Jin-Sheng Huang, Guy C Le Breton, Athar H Chishti
Integrins function as bi-directional signaling transducers that regulate cell-cell and cell-matrix signals across the membrane. A key modulator of integrin activation is talin, a large cytoskeletal protein that exists in an autoinhibited state in quiescent cells. Talin is a large 235-kDa protein composed of an N-terminal 45-kDa FERM (4.1, ezrin-, radixin-, and moesin-related protein) domain, also known as the talin head domain, and a series of helical bundles known as the rod domain. The talin head domain consists of four distinct lobes designated as F0-F3...
December 23, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27771095/transanal-hemorrhoid-dearterialization-is-a-safe-and-effective-outpatient-procedure-for-the-treatment-of-hemorrhoidal-disease
#13
Zoran Bjelanovic, Miroljub Draskovic, Milic Veljovic, Ivan Lekovic, Menelaos Karanikolas, Dusica Stamenkovic
INTRODUCTION: This prospective, observational study evaluated transanal dearterialization (THD) efficacy and safety in grade 2-4 hemorrhoids (HD). METHODS: THD was performed under sedation-locoregional anesthesia in 402 outpatients. Patients had follow-up evaluation 3 days, 2 weeks, 1, 6 and 12 months postoperatively. Postoperative complications and recurrence of symptoms at 12 months were analyzed. The relationship between the learning curve and the number of postoperative complications was studied...
December 2016: Cirugía Española
https://www.readbyqxmd.com/read/27687850/helicobacter-pylori-dna-isolation-in-the-stool-an-essential-pre-requisite-for-bacterial-noninvasive-molecular-analysis
#14
Floriana Giorgio, Enzo Ierardi, Claudia Sorrentino, Mariabeatrice Principi, Michele Barone, Giuseppe Losurdo, Andrea Iannone, Antonio Giangaspero, Rosa Monno, Alfredo Di Leo
PURPOSE: Real-time polymerase chain reaction (RT-PCR) is a widely used technique for bacterial and viral infection diagnosis. Herein, we report our preliminary experience in retrieving H. pylori genetic sequences in stools and analyzing genotypic clarithromycin resistance by RT-PCR (noninvasive), with the aim of comparing this procedure with that performed on biopsy samples (invasive). MATERIALS AND METHODS: After 'in vitro' demonstration of H. pylori DNA detection from pure and stool-mixed bacteria, 52 consecutive patients at the first diagnosis of infection were investigated...
December 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27661139/mapping-the-mmpi-2-rf-substantive-scales-onto-internalizing-externalizing-and-thought-dysfunction-dimensions-in-a-forensic-inpatient-setting
#15
Isabella E Romero, Nasreen Toorabally, Danielle Burchett, Anthony M Tarescavage, David M Glassmire
Contemporary models of psychopathology-encompassing internalizing, externalizing, and thought dysfunction factors-have gained significant support. Although research indicates the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008 /2011) measures these domains of psychopathology, this study addresses extant limitations in MMPI-2-RF diagnostic validity research by examining associations between all MMPI-2-RF substantive scales and broad dichotomous indicators of internalizing, externalizing, and thought dysfunction diagnoses in a sample of 1,110 forensic inpatients...
September 23, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27610920/affordable-headphones-for-accessible-screening-audiometry-an-evaluation-of-the-sennheiser-hd202-ii-supra-aural-headphone
#16
Mathieu Van der Aerschot, De Wet Swanepoel, Faheema Mahomed-Asmail, Herman Carel Myburgh, Robert Henry Eikelboom
OBJECTIVE: Evaluation of the Sennheiser HD 202 II supra-aural headphones as an alternative headphone to enable more affordable hearing screening. DESIGN: Study 1 measured the equivalent threshold sound pressure levels (ETSPL) of the Sennheiser HD 202 II. Study 2 evaluated the attenuation of the headphones. Study 3 determined headphone characteristics by analyzing the total harmonic distortion (THD), frequency response and force of the headband. STUDY SAMPLE: Twenty-five participants were included in study 1 and 15 in study 2 with ages ranging between 18 and 25...
November 2016: International Journal of Audiology
https://www.readbyqxmd.com/read/27601250/doppler-guided-transanal-hemorrhoidal-dearterialization-dg-thd-versus-stapled-hemorrhoidopexy-sh-in-the-treatment-of-third-degree-hemorrhoids-clinical-results-at-short-and-long-term-follow-up
#17
S Leardi, B Pessia, M Mascio, F Piccione, M Schietroma, R Pietroletti
INTRODUCTION: The stapled hemorrhoidopexy (SH) and the Doppler-guided transanal hemorrhoidal dearterialization (DG-THD) are minimally invasive procedures for the surgical treatment of hemorrhoids. This study aims to verify the efficacy of the DG-THD versus the SH in the treatment of third-degree hemorrhoids. METHOD: One hundred consecutive patients were causally allocated to either procedure, obtaining two groups of 50 pts. A clinical examination was performed at 3, 7, 15, and 30 days after the operation...
November 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27548281/phosphatidylinositol-4-5-bisphosphate-modulates-the-affinity-of-talin-1-for-phospholipid-bilayers-and-activates-its-autoinhibited-form
#18
Xin Ye, Mark A McLean, Stephen G Sligar
Integrins are vital transmembrane receptors that mediate cell-cell and cell-extracellular matrix interactions and signaling. Talin is a 270 kDa protein and is considered a key regulator of integrin activity. The interaction between talin and integrin is commonly regarded as the final step of inside-out activation. In the cytosol, talin adopts an autoinhibited conformation, in which the C-terminal rod domain binds the N-terminal head domain, preventing the interactions of the head domain with the membrane surface and the integrin cytoplasmic domain...
September 13, 2016: Biochemistry
https://www.readbyqxmd.com/read/27531763/-effect-of-interferon-combined-with-thalidomid-on-hel-cell-apoptosis-and-jak2v617f-mutation-gene-expression
#19
Xiao-Xie Wu, Lian-Guo Xue, Li-Dong Zhao, Ying Wang, Zhi-Mei Cai
OBJECTIVE: To investigate the effects of interferon-α2b combined with thalidomid(THD) on the proliferation and apoptosis of HEL cells, and expression of JAK2V617F-mutated gene. METHODS: The cell survival rates were assayed by CCK-8 after HEL cells were treated by interferon-α2b, thalidomid and thalidomid combined with interferon-α2b for 24, 48 and 72 hours, while the apoptosis and expression of JAK2V617F mutation gene were detected by flow cytometry and fluorescence quantitative PCR respectively after treatmemt for 48 hours...
August 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/27508112/the-production-of-s-equol-from-daidzein-is-associated-with-a-cluster-of-three-genes-in-eggerthella-sp-yy7918
#20
Yuika Kawada, Shinichiro Yokoyama, Emiko Yanase, Toshio Niwa, Tohru Suzuki
Daidzein (DZN) is converted to equol (EQL) by intestinal bacteria. We previously reported that Eggerthella sp. YY7918, which is found in human feces, is an EQL-producing bacterium and analyzed its whole genomic sequence. We found three coding sequences (CDSs) in this bacterium that showed 99% similarity to the EQL-producing enzymes of Lactococcus sp. 20-92. These identified CDSs were designated eqlA, eqlB, and eqlC and thought to encode daidzein reductase (DZNR), dihydrodaidzein reductase (DHDR), and tetrahydrodaidzein reductase (THDR), respectively...
2016: Bioscience of Microbiota, Food and Health
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