keyword
https://read.qxmd.com/read/37296804/forestalling-hungry-bone-syndrome-after-parathyroidectomy-in-patients-with-primary-and-renal-hyperparathyroidism
#21
REVIEW
Mara Carsote, Claudiu Nistor
UNLABELLED: Hungry bone syndrome (HBS), severe hypocalcemia following parathyroidectomy (PTX) due to rapid drop of PTH (parathormone) after a previous long term elevated concentration in primary (PHPT) or renal hyperparathyroidism (RHPT), impairs the outcome of underlying parathyroid disease. OBJECTIVE: overview HBS following PTx according to a dual perspective: pre- and post-operative outcome in PHPT and RHPT. This is a case- and study-based narrative review. INCLUSION CRITERIA: key research words "hungry bone syndrome" and "parathyroidectomy"; PubMed access; in extenso articles; publication timeline from Inception to April 2023...
June 2, 2023: Diagnostics
https://read.qxmd.com/read/37238415/obesity-risk-assessment-for-spanish-speaking-immigrant-families-with-young-children-in-the-united-states-reliability-and-validity-with-nutrient-values
#22
JOURNAL ARTICLE
Marilyn S Townsend, Mical K Shilts, Louise Lanoue, Christiana Drake, L Karina Díaz Rios, Nancy L Keim, Dennis M Styne, Lenna L Ontai
The purpose is to examine validity and reliability for an obesity risk assessment tool developed in Spanish for immigrant families with children, 3-5 years old using an 8-week cross-sectional design with data collected over 1 year at Head Start and Special Supplemental Nutrition Program for Women, Infants and Children [WIC]. Parent/child dyads (206) provided a child obesity risk assessment, three child modified 24 h dietary recalls, three child 36+ h activity logs and one parent food behavior checklist. Main outcome measures were convergent validity with nutrients, cup equivalents, and diet quality and three assessments of reliability that included item difficulty index, item discrimination index, and coefficient of variation...
May 12, 2023: Children
https://read.qxmd.com/read/37200336/association-between-body-mass-index-and-posterior-spine-fusion-among-patients-with-adolescent-idiopathic-scoliosis
#23
JOURNAL ARTICLE
Carrie T Chan
INTRODUCTION: Previous studies have found mixed associations between body mass index (BMI) and adolescent idiopathic scoliosis (AIS) incidence and progression. The aim of this study was to examine the association between BMI and the incidence of posterior spine fusion (PSF) among pediatric patients with AIS. METHODS: This was a retrospective cohort study of patients diagnosed with AIS at a single large tertiary care center between January 1, 2014 and December 31, 2020...
2023: PloS One
https://read.qxmd.com/read/37189944/micronutrient-deficiency-in-children-and-adolescents-with-obesity-a-narrative-review
#24
REVIEW
Valeria Calcaterra, Elvira Verduci, Chiara Milanta, Marta Agostinelli, Carolina Federica Todisco, Federica Bona, Jonabel Dolor, Alice La Mendola, Martina Tosi, Gianvincenzo Zuccotti
Childhood obesity represents a serious public health burden. Despite excessive dietary consumption, children with obesity present high rates of micronutrient deficiencies, such as deficiencies in minerals and specific vitamins; micronutrient deficiencies may have a pathogenic role in obesity-related metabolic comorbidities. In this narrative review, we analyzed the main deficiencies associated with obesity, their clinical consequences, and the evidence about a possible supplementation. Iron; vitamins A, B, C, D, and E; folic acid; zinc; and copper deficiencies represent the most common deficient microelements...
April 7, 2023: Children
https://read.qxmd.com/read/37189890/atherogenic-index-of-plasma-aip-and-its-association-with-fatty-liver-in-obese-adolescents
#25
JOURNAL ARTICLE
Hüseyin Dağ, Fatih İncirkuş, Okan Dikker
BACKGROUND: The atherogenic index of plasma (AIP) is the base-10 logarithmic conversion of the triglyceride to high-density lipoprotein cholesterol ratio [AIP = log10 (triglyceride/HDL cholesterol)]. Some studies have found a link between low serum vitamin D levels, AIP, and fatty liver. This study was conducted to evaluate the relationship between AIP levels, fatty liver, and vitamin D levels in obese adolescents aged 10-17 years. METHODS: This study included 136 adolescents, including 83 obese and 53 healthy controls, in the age range of 10-17 years...
March 29, 2023: Children
https://read.qxmd.com/read/37178775/effects-of-vitamin-d-supplementation-in-obese-and-overweight-children-and-adolescents-a-systematic-review-and-meta-analysis
#26
REVIEW
Antonio Corsello, Marina Macchi, Veronica D'Oria, Chiara Pigazzi, Ilaria Alberti, Giorgio Treglia, Valentina De Cosmi, Alessandra Mazzocchi, Carlo Agostoni, Gregorio Paolo Milani
Due to the lipophilic nature of vitamin D, overweight and obese patients have an increased risk of inadequate circulating 25-hydroxy-vitamin D (25(OH)D) concentrations. Vitamin D deficiency has in turn several consequences especially among children and adolescents. Therefore, a few supplementation strategies of vitamin D for pediatric subjects with an excessive body weight have been proposed, but their efficacy remains controversial. The aim of this systematic review and meta-analysis was to evaluate the effect of vitamin D supplementation in overweight and obese children and adolescents...
June 2023: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://read.qxmd.com/read/37173405/sex-and-obesity-status-modify-the-association-between-vitamin-d-and-eczema-among-adolescents
#27
JOURNAL ARTICLE
Ali H Ziyab, Abdullah Al-Taiar, Reem Al-Sabah, Lemia Shaban, Zainab Almousa, Anwar H AlBaloul, Wilfried Karmaus
BACKGROUND: Epidemiologic studies have reported inconsistent associations between vitamin D and eczema. This study sought to assess whether sex and obesity status could modify the association between vitamin D and eczema. METHODS: A cross-sectional study enrolled 763 adolescents in Kuwait. 25-hydroxyvitamin D (25(OH)D) was measured in venous blood. Current eczema was defined according to clinical history and characteristic morphology and distribution. RESULTS: In sex-stratified analysis, decreased 25(OH)D levels were associated with increased current eczema prevalence among males (adjusted odds ratio (aOR)tertile 1 vs...
May 12, 2023: Pediatric Research
https://read.qxmd.com/read/37154302/the-relationship-between-vitamin-d-deficiency-and-protein-oxidation-among-obese-children
#28
JOURNAL ARTICLE
Ilknur Surucu Kara, Cuma Mertoglu, Gülsah Siranli, Yusuf Kemal Arslan, Gamze Gok, Ozcan Erel
Aim: The aim of the study is to examine the relationship between obesity, Vitamin-D deficiency, and protein oxidation. Methods: Thiol-disulfide homeostasis, Vitamin-D, ischemia modified albumin, insulin, and lipid levels were compared among obese, pre-obese and normal-weight healthy children. Results: A total of 136 children (69 boys and 67 girls) were included in the study. The vitamin-D levels of obese children were lower than those of pre-obese and normal weight (p < 0.05). In the normal weight group, total thiol and native thiol were lower in the pubertal period than in adolescence; were higher in those with sufficient Vitamin-D level than those with insufficient and deficient Vitamin-D (p < 0...
May 8, 2023: Fetal and Pediatric Pathology
https://read.qxmd.com/read/37074225/an-endocrinological-perspective-on-22q11-2-deletion-syndrome-a-single-center-experience
#29
JOURNAL ARTICLE
Yasemin Denkboy Ongen, Sebnem Ozemri Sag, Sehime Gulsun Temel, Erdal Eren
INTRODUCTION: 22q11.2 deletion syndrome (22q11.2 DS) is the most common chromosomal microdeletion disorder. Associated problems with this syndrome may include cardiac abnormalities, immune dysfunction, facial dysmorphism, endocrine, genitourinary and gastrointestinal problems, and developmental delay. This study aims to evaluate and present all endocrinological findings of patients with 22q11.2 DS. MATERIALS AND METHODS: The seventeen participants in this study were all FISH confirmed 22q11...
April 19, 2023: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/37013431/metabolic-associated-fatty-liver-disease-in-children-and-adolescents-mechanisms-of-a-silent-epidemic-and-therapeutic-options
#30
JOURNAL ARTICLE
Antonella Mosca, Luca Della Volpe, Maria Rita Sartorelli, Donatella Comparcola, Silvio Veraldi, Anna Alisi, Giuseppe Maggiore
Non-alcoholic fatty liver disease (NAFLD) is now identified as a hepatic sign of metabolic syndrome and is the most frequent cause of chronic liver disease in all ages. It is assumed that a genetic predisposition associated with epigenetic factors participates in the evolution of this condition. Visceral obesity and insulin resistance (IR) have always been considered the most important causative factors of Metabolic Syndrome (MetS) and NAFLD, but currently, the interaction between genetic heritage and environmental factors is increasingly considered fundamental in the genesis of metabolic disorders associated with NAFLD...
2024: Current Pediatric Reviews
https://read.qxmd.com/read/36919271/dual-burden-of-individual-malnutrition-in-children-1-4%C3%A2-years-findings-from-the-colombian-nutritional-health-survey-ensin-2015
#31
JOURNAL ARTICLE
Adriana N Castillo, Milton F Suarez-Ortegón
BACKGROUND: To date there are no studies with estimation of multiple types of double burden of individual malnutrition (DBIM) and evaluation of associated determinants. OBJECTIVE: To estimate the prevalence and social determinants associated with the double burden of individual malnutrition in children aged 1-4 years. METHODS: A cross-sectional study was conducted using data from Colombian nutritional heath survey ENSIN 2015. Global DBIM was analysed on the basis of excess weight and the presence of one or more micronutrient deficiencies (vitamin A, D, zinc, or iron) and/or stunting...
March 14, 2023: Pediatric Obesity
https://read.qxmd.com/read/36917420/high-levels-of-light-tnfsf14-in-patients-with-prader-willi-syndrome
#32
JOURNAL ARTICLE
M F Faienza, G Brunetti, D Fintini, G Grugni, M G Wasniewska, A Crinò, G D'Amato, L Piacente, A Oranger, M Dicarlo, S Colucci, M Grano
PURPOSE/METHODS: Prader-Willi syndrome (PWS) is a rare genetic disorder displaying different clinical features, including obesity and bone impairment. LIGHT/TNFSF14 is a cytokine produced by immune cells affecting both fat and bone metabolism. The present study aimed to evaluate LIGHT serum levels in 28 children and 52 adult PWS patients compared to age and sex-matched controls, as well as correlations with parameters of bone and fat metabolism. RESULTS: Median serum LIGHT levels were significantly increased in pediatric PWS with respect to controls [255...
March 14, 2023: Journal of Endocrinological Investigation
https://read.qxmd.com/read/36913250/response-to-vitamin-d-replacement-therapy-in-obese-children-and-adolescents-with-vitamin-d-deficiency-a-randomized-controlled-trial
#33
JOURNAL ARTICLE
Sarah Deruyter, Stephanie Van Biervliet, Ann De Guchtenaere
OBJECTIVES: Vitamin D deficiency is common in the pediatric group with obesity and is a risk factor for metabolic syndrome. Supplementation of vitamin D may require higher dosing than in normal-weight children. The aim of our study was to investigate the response of supplementation on vitamin D levels and the metabolic profile in youths with obesity. METHODS: Children and adolescents with obesity (Body mass index >2.3 SDS, age ≤18 years) and hypovitaminosis D (level <20 μg/L) who entered a residential weight-loss program in Belgium, were included during summer...
March 13, 2023: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/36856888/oral-vitamin-d-supplementation-and-body-weight-in-children-and-adolescents-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#34
REVIEW
Sepideh Soltani, Sara Beigrezaei, Shima Abdollahi, Cain C T Clark, Marziyeh Ashoori
UNLABELLED: This study was designed to ascertain whether oral vitamin D supplementation (oral supplementation and fortified foods) is associated with changes in body weight measures in children and adolescents, using a systematic review and meta-analysis of randomized controlled trials (RCTs). PubMed, Scopus, Cochrane, and Web of Science databases were searched from inception to October 28, 2022. The mean difference and corresponding 95% confidence interval (CI) of interested outcomes were pooled using a random-effects model...
May 2023: European Journal of Pediatrics
https://read.qxmd.com/read/36832332/nutritional-aspects-of-juvenile-idiopathic-arthritis-an-a-to-z-for-dietitians
#35
REVIEW
Maria G Grammatikopoulou, Konstantinos Gkiouras, Vasiliki Syrmou, Tonia Vassilakou, Theodora Simopoulou, Chistina G Katsiari, Dimitrios G Goulis, Dimitrios P Bogdanos
Juvenile idiopathic arthritis (JIA) represents a chronic, autoimmune, rheumatic musculoskeletal disease with a diagnosis before 16 years of age. Chronic arthritis is a common manifestation in all JIA subtypes. The nature of JIA, in combination to its therapy often results in the development of nutrition-, gastrointestinal (GI)- or metabolic-related issues. The most-common therapy-related nutritional issues involve methotrexate (MTX) and glucocorticosteroids (GCC) adverse events. MTX is a folic acid antagonist, thus supplementation with folic acid in required for improving GI side effects and correcting low serum levels...
January 23, 2023: Children
https://read.qxmd.com/read/36832311/evaluating-the-arterial-stiffness-as-a-useful-tool-in-the-management-of-obese-children
#36
JOURNAL ARTICLE
Monica Simina Mihuta, Dana Stoian, Andreea Borlea, Cristina Mihaela Roi, Oana-Alexandra Velea-Barta, Ioana Mozos, Corina Paul
Childhood obesity speeds up the development of arterial stiffness and progressively increases the values of arterial pressure. The purpose of this study is to investigate the value of using pulse wave analysis (PWA) to measure arterial stiffness as a sign of vascular wall impairment in obese children. The research was focused on 60 subjects: 33 obese and 27 normal-weight. Ages ranged from 6 to 18 years old. PWA includes parameters such as pulse wave velocity (PWV), augmentation index (AIx), peripheral and central blood pressure (SBP, DBP, cSBP, cDBP), heart rate, and central pulse pressure (cPP)...
January 18, 2023: Children
https://read.qxmd.com/read/36814347/vitamin-d-status-in-healthy-italian-school-age-children-a-single-center-cross-sectional-study
#37
JOURNAL ARTICLE
Tiziana Galeazzi, Sara Quattrini, Dorina Pjetraj, Simona Gatti, Chiara Monachesi, Elisa Franceschini, Luisita Marinelli, Giulia N Catassi, Elena Lionetti, Carlo Catassi
BACKGROUND: Vitamin D is involved in calcium homeostasis and bone metabolism, although its extra-skeletal actions are also well-known. Low serum 25(OH)D levels are common both in adults and children worldwide. METHODS: The purpose of this cross-sectional study was to determine the distribution of 25(OH)D levels in a cohort of healthy Italian school-age children, aged 5-10 years, in relationship to determinants of vitamin D deficiency such as season, BMI, gender, age and ethnicity...
February 22, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/36800541/orthopaedic-diagnoses-in-the-black-pediatric-population
#38
JOURNAL ARTICLE
Carla M Bridges, Rashmi Agarwal, Ellen M Raney
The Black pediatric population is one that has been historically underserved and continues to have unmet needs. Factors including lack of diversity in orthopaedic studies and in historical standards, such as bone age, may inadvertently lead to inferior care. There are certain conditions in this population for which the practicing orthopaedic surgeon should have a higher degree of suspicion, including slipped capital femoral epiphysis, Blount disease, and postaxial polydactyly. Systemic diseases with higher rates in this population have orthopaedic manifestations, including sickle cell disease, vitamin D deficiency, and obesity...
February 16, 2023: Journal of the American Academy of Orthopaedic Surgeons
https://read.qxmd.com/read/36759131/family-physicians-can-should-do-what-where-and-how
#39
EDITORIAL
Marjorie A Bowman, Dean A Seehusen, Christy J W Ledford
This issue's teasers: A broad scope of care by family physicians could be incentivized and has positive outcomes. Family physicians could do more dermoscopy-a mixed specialty group of experts provide information on diagnosis with associated features and proficiency standards for primary care clinicians. Clinicians could trust more, and do less, such as adult measles-mumps-rubella boosters. Family physicians differ from pediatricians on how to deliver vitamin D to newborns. Practice scope varies by location...
February 8, 2023: Journal of the American Board of Family Medicine: JABFM
https://read.qxmd.com/read/36708456/multicentric-italian-case-control-study-on-25oh-vitamin-d-levels-in-children-and-adolescents-with-prader-willi-syndrome
#40
MULTICENTER STUDY
F M Panfili, A Convertino, G Grugni, L Mazzitelli, S Bocchini, A Crinò, G Campana, M Cappa, M Delvecchio, M F Faienza, M R Licenziati, M Mariani, S Osimani, R Pajno, G Patti, I Rutigliano, M Sacco, E Scarano, D Fintini
PURPOSE: 25OHD levels in patients with Prader-Willi Syndrome (PWS), the most frequent cause of genetic obesity with a peculiar fat mass distribution, are still debated. Insulin resistance (IR), Body Mass Index-SDS (BMI-SDS), Growth Hormone Therapy (GHT), and puberty onset seem to interact with 25OHD levels. The objectives of the study are: (1) To analyze 25OHD levels in pediatric PWS patients in comparison with a control group (CNT) (2) To evaluate a possible correlation between BMI-SDS, HOMA-IR, puberty, GHT, and 25OHD levels...
July 2023: Journal of Endocrinological Investigation
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